ER-PM membrane contact site regulation by yeast ORPs and membrane stress pathways. by Evan Quon, Aleksa Nenadic, Mohammad F Zaman, Jesper Johansen, Christopher T Beh

“…In response to the inactivation of all Osh proteins, the yeast E-Syt (extended-synaptotagmin) homologue Tcb3p is post-transcriptionally upregulated thereby generating additional Tcb3p-dependent ER-PM MCSs for recruiting more cortical ER to the PM. …”
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A Fast Recognition Method for Space Targets in ISAR Images Based on Local and Global Structural Fusion Features with Lower Dimensions by Hong Yang, Yasheng Zhang, Wenzhe Ding

“…This method performs the trace transformation along the longest axis of the ISAR image to generate the global trace feature of the space target ISAR image. …”
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SlidingConv: Domain-Specific Description of Sliding Discrete Cosine Transform Convolution for Halide by Yamato Kanetaka, Hiroyasu Takagi, Yoshihiro Maeda, Norishige Fukushima

“…The experimental results showed that SlidingConv is faster than the hand-tuned CPU code and 1/1900 of the hand-tuned code length, running more efficiently than de facto libraries like OpenCV. …”
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Acid ceramidase-1 (ASAH1/aCDase) an important for anticancer drug discovery: a review by Seemarani M. Pawar, Trupti Chitre, Prasad Dandawate

“…Sphingolipids are major structural components of cell membranes, playing key roles in maintaining structural integrity, fluidity, and barrier function. Sphingolipids are diverse and involved in regulating growth, the cell cycle, cell motility, adhesion, migration, and more by influencing cell signaling functions. …”
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Age-Specific Physiological Adjustments of <i>Spirodela polyrhiza</i> to Sulfur Deficiency by Vesna Peršić, Anja Melnjak, Lucija Domjan, Günther Zellnig, Jasenka Antunović Dunić

“…Under S deficit, mother fronds relied on stored reserves to maintain functional PSII but accumulated reduced PQ pools, slowing electron flow beyond PSII. …”
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Multiple Rows Mixers and Hsilu by Xiaobin Yu, Meicheng Liu

“…This approach can automatically generate linear layers that meet the requirements of a given branch number. …”
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Sensitivity analysis of reliability constrained, eco optimal solar, wind, hydrogen storage based islanded power system by Nishant Thakkar, Priyanka Paliwal, Deepa Kaliyaperumal, V. Ravikumar Pandi, Narayan Prasad Gupta, Marco Merlo

“…Abstract The global energy expansion strategy has incorporated islanded renewable energy-based power generation systems to electrify remote communities. …”
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Multidimensional Fragility Analysis for a NEES Frame Structure by Integrating a New Energy Damage Index: Cumulative Plastic Strain by Qiang Wang, Ziyan Wu

“…Results show that (1) CPS damage index can fully consider the cumulative effect of damage under earthquakes, which makes up for the deficiency of the interstory drift damage index in this aspect, (2) the multidimensional fragility framework can deal with the PLS correlation and EDP correlation simultaneously, which will generate a more precise seismic damage assessment result, and (3) multidimensional fragility is sensitive to PLS threshold values and PLS correlation parameters.…”
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Nb-FAR-1: A key developmental protein affects lipid droplet accumulation and cuticle formation in Nippostrongylus brasiliensis. by Wenmin Qi, Fei Shen, Chuyue Wang, Juan Wen, Xi Pan, Zhongying Zhao, Lihua Xiao, Yaoyu Feng, Dongjuan Yuan

“…Fatty acid and retinol binding proteins (FARs) are lipid-binding protein that may be associated with modulating nematode pathogenicity to their hosts. However, the functional mechanism of FARs remains elusive. We attempt to study the function of a certain FAR that may be important in the development of Nippostrongylus brasiliensis. …”
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Genetic heterogeneity of congenital cerebral palsy and the concept of the neurotropic genome by P. L. Sokolov, N. V. Chebanenko, A. G. Prityko, P. A. Romanov

“…Background. Currently, more than 500 genes are known, in one degree or another associated with the development of the phenotype of congenital cerebral palsy (CP). …”
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Optimization of a Navigation System for Autonomous Charging of Intelligent Vehicles Based on the Bidirectional A* Algorithm and YOLOv11n Model by Shengkun Liao, Lei Zhang, Yunli He, Junhui Zhang, Jinxu Sun

“…The system utilizes the improved bidirectional A* algorithm to generate collision-free paths from the starting point to the charging area, dynamically adjusting the heuristic function by combining node–target distance and search iterations to optimize bidirectional search weights, pruning expanded nodes via a greedy strategy and smoothing paths into cubic Bézier curves for practical vehicle motion. …”
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A novel lightweight hybrid cryptographic framework for secure smart card operations by Kranthi Kumar Singamaneni

“…In this article, we propose a novel hybrid crypto standard to enhance the security and privacy of the transactions using smart cards, to achieve this we integrate Elliptic Curve Cryptography Curve25519 to generate secure keys, SPECK block cipher for lightweight encipherment with a powerful hash function for message authentication and integrity checks called PHOTON. …”
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Security-Constrained Multi-Stage Robust Dynamic Economic Dispatch with Bulk Storage by Li Dai, Renshi Ye, Dahai You, Xianggen Yin

“…The master problem determines the generator output and storage charge and discharge, and the sub-problem determines the total generation and storage reserve capacity to cover all the generator N-1 contingencies. …”
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Refinement of Recloser Operation and Safety Enhancement in Distribution Systems: A Study Based on Real Data by Geonho Kim, Tae-Hwan Kim, Jun-Hyeok Kim

“…First, an analysis of reclosure counts revealed that over 73% of faults were cleared after the first reclosure, and when the second reclosure was included, more than 90% were successfully restored. This finding suggests that reducing the number of reclosures from the standard three to one or two would not significantly impact fault restoration performance while simultaneously reducing arc generation, thereby improving safety. …”
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Proteomic Analysis of Extracellular Vesicles Identifies CDCP1 as Critical Metastasis‐Related Glycoprotein in Lung Cancer by Lu Zhang, Yan Wu, Suntao Li, Miao Guo, Jiaqi Zhao, Chengxi Cao, Yan Zhang, Hua Xiao

“…Compared to 95C EVs, 23 glycoproteins were significantly upregulated more than 20‐fold in 95D EVs, including CDCP1, TNC, NCAM2, and ITGA4. …”
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Quantifying the Impact of Comorbidities on Outcomes Following Surgery for Osteoporotic Vertebral Compression Fractures by Anmol Gupta, Thomas Cha, Joseph Schwab, Harold Fogel, Daniel Tobert, Afshin E. Razi, Carl Paulino, Christopher M. Bono, Stuart Hershman

“…Introduction Studies have shown that osteoporotic patients are more likely to have medical or surgical complications postoperatively. …”
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Cytotoxic Effects of ZnO and Ag Nanoparticles Synthesized in Microalgae Extracts on PC12 Cells by Giacomo Fais, Agnieszka Sidorowicz, Giovanni Perra, Debora Dessì, Francesco Loy, Nicola Lai, Paolo Follesa, Roberto Orrù, Giacomo Cao, Alessandro Concas

“…This study emphasizes the crucial role of the synthesis environment and bioactive compounds from <i>C. vulgaris</i> in modulating nanoparticle surface chemistry, ROS generation, and cytotoxicity. The results provide valuable insights for designing safer and more effective nanomaterials for biomedical applications, especially for targeting tumor-like cells, by exploring the relationships between nanoparticle size, polarity, capping agents, and nanocomposite structures.…”
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Artificial intelligence analysis of thermal energy for convectively heated ternary nanofluid flow in radiated channel considering viscous dissipations aspects by Hamid Qureshi, Amjad Ali Pasha, Muhammad Asif Zahoor Raja, Zahoor Shah, Salem Algarni, Talal Alqahtani, Waqar Azeem Khan, Moinul Haq

“…This research works to establish the convective heat transfer coefficient (CHTC) of new improved ternary hybrid functionalized nanofluids with CuO, Fe2O3, and SiO2 nanoparticles in polymeric fluid. …”
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Structure-dependent degradation of milk oligosaccharides by newly isolated intestinal commensal bacterial strains from suckling piglets and rabbits by Mathilde Rumeau, Sead Chadi, Frederic Pepke, Martin Beaumont, Cláudia M. Vicente, Agathe Juppeau, Céline Vandecasteele, Laurent Cauquil, Géraldine Pascal, Philippe Langella, Christelle Knudsen, Sylvie Combes, Rebeca Martín

“…Milk oligosaccharide fermentation generated a more diverse metabolome compared to glucose. …”
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Amniotic fluid-derived stem cells: potential factories of natural and mimetic strategies for congenital malformations by Cristiane S. R. Fonteles, Julia Enterria-Rosales, Ying Lin, John W. Steele, Ramiro A. Villarreal-Leal, Jing Xiao, Daniel I. Idowu, Beck Burgelin, Bogdan J. Wlodarczyk, Richard H. Finnell, Bruna Corradetti

“…The possibility to exploit both formulations as mRNA-therapeutics was explored by evaluating cell uptake in two different cell types(fibroblasts, and macrophages) and mRNA functionality overtime in an in vitro experimental setting as well as in an ex vivo, whole embryo culture using pregnant C57BL6 dams. …”
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