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2941
Artificial Intelligence as Assessment Tool in Occupational Therapy: A Scoping Review
Published 2025-04-01“…Occupational therapy (OT) is vital in improving functional outcomes and aiding recovery for individuals with long-term disabilities, particularly those resulting from neurological diseases. …”
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2942
ROS‐Driven Nanoventilator for MRSA‐Induced Acute Lung Injury Treatment via In Situ Oxygen Supply, Anti‐Inflammation and Immunomodulation
Published 2025-05-01“…This nanocapsule can effectively improve the stability and loading rate of enzymes, and enhance their enzyme cascade efficiency, thereby efficiently consuming •O2− and H2O2 to generate O2 in situ and reducing ROS level. More interestingly, in situ O2 supply can effectively relieve lung hypoxia to reduce HIF‐1α expression and balance the number of M1/M2 macrophages to reduce the levels of TNF‐α, IL‐1β and IL‐6, thereby alleviating the inflammatory response. …”
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2943
Sugarcane Straw Hemicellulose Extraction by Autohydrolysis for Cosmetic Applications
Published 2025-03-01“…Sugarcane is a popular crop whose cultivation generates a wide range of by-products. The aim was to optimize the hydrothermal extraction of hemicellulose from sugarcane straw using response-surface methods with a two-factor composite design and to assess its functional qualities. …”
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2944
Regulatory role of MicroRNA164 in heat and salinity stress responses via candidate target genes during seed germination in petunia
Published 2025-05-01“…This study explores its role in regulating stress responses in petunia by generating MIR164 overexpression (MIR164-ox) and miR164 suppression (miR164-STTM) lines. …”
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2945
Advances in enhancing hydrodeoxygenation selectivity of lignin-derived oxygenates: From synthetic strategies to fundamental techniques
Published 2025-02-01“…Thus, the goal is to selectively remove oxygen-containing functional groups while preserving the benzene ring structure. …”
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2946
Design, Fabrication, and Performance Evaluation of a Food Solar Dryer
Published 2024-11-01“…With a one-year payback period, an economic attribute of 3.26, and a life cycle benefit of BDT 310,651 (USD 2597.68), economics show the dryer’s feasibility. The solar dryer functioned faster than direct sun drying due to its significantly higher heat generation. …”
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2947
DNA metabarcoding of benthic algae and associated eukaryotes from Lake Baikal in the face of rapid environmental changes
Published 2022-03-01“…About 15 thousand reads of the 18S rRNA marker were obtained by applying NGS (next-generation sequencing). The species of algae dominating in the number of reads, as well as the difficult-to-identify taxa (Stramenopiles, Alveolata, Euglenozoa, Chromista, Rhizaria, Amoebozoa, etc.), which play an important role in the functioning and formation of the structure of algal communities, were revealed. …”
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2948
Modulating the serine metabolism in human differentiated astrocytes: an integrated multi omics approach
Published 2025-07-01“…IntroductionAstrocytes are the major source of L-serine (L-Ser) in the brain: the glycolytic intermediate D-3-phosphoglycerate is converted into L-Ser through the phosphorylated pathway (PP) made up of three enzymes, phosphoglycerate dehydrogenase (PHGDH), phosphoserine aminotransferase (PSAT) and phosphoserine phosphatase (PSP), recently proposed to generate a metabolic assembly named serinosome. In the central nervous system, L-Ser is used for a number of functions, including the synthesis of glycine (Gly) and D-serine (D-Ser), the two key NMDAR co-agonists.MethodsHere, we used iPSC-derived human astrocytes as a cellular model to evaluate the impact on cell metabolism of the overexpression of each of the three enzymes of the PP as GFP-tagged proteins.ResultsThe subcellular cytosolic localization of PP enzymes remains unchanged compared to endogenous proteins, while the complex formation is increased in all cases. …”
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2949
Deciphering the role of dietary modifications and gut dysbiosis in Non-Alcoholic Fatty Liver Disease
Published 2025-06-01“…Approximately one-third of the total population is affected by NAFLD. The more aggressive form of NAFLD, non-alcoholic steatohepatitis (NASH) could progress to liver failure, fibrosis, cirrhosis, hepatocellular carcinoma and even death. …”
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2950
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2951
Antibody–Drug Conjugates (ADCs): current and future biopharmaceuticals
Published 2025-04-01“…How can ADCs be designed to be safer and more efficient? What is the future development direction of ADCs? …”
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2952
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2953
TGFβ-specific T cells induced by a TGFβ-derived immune modulatory vaccine both directly and indirectly modulate the phenotype of tumor-associated macrophages and fibroblasts
Published 2024-02-01“…Reducing immunosuppression and immune exclusion in pancreatic tumors by targeting TAMs and CAFs with the TGFβ-based immune modulatory vaccine emerges as an innovative strategy for the generation of a more favorable environment for immune-based therapies, such as immune checkpoint inhibitors.…”
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2954
Agrobiological features of the new naked oat variety Baget
Published 2018-04-01“…Naked oat variety Baget was created by method of individual selection from cross population ОА 503/1 (Canada) * Tumensky golozerny (Russia) with following control of trait in further generations. The variety is intended for production of food grain (children, diet, functional, and gluten-free nutrition) as well as for grain forage. …”
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2955
Application Models and Innovative Approaches of Smart Libraries from the Perspective of MR Technology
Published 2024-09-01“…The mixed reality (MR) Technology is a new intelligent technology that integrates the advantages of augmented reality (AR) and virtual reality (VR), makes virtual objects coexist in the physical world, and integrates the functions of human perception, computer processing and environmental input. …”
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2956
Descriptive epidemiology of gynecologic and breast cancers between 1988 and 2018 in Burkina Faso, West Africa
Published 2024-07-01“…However, there are no data on its full extent in Burkina Faso given the lack of functioning national registry of cancer. This study aims to determine the incidence of gynecologic and breast cancers. …”
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2957
Linear Active Disturbance Rejection Control-Based Voltage Controller for Buck and Boost DC/DC Converters in DC Distribution Grids
Published 2025-01-01“…In addition, the physical significance of the converter’s states allows the integration of additional control functions, relying on the electrical quantities of the converter, for the enhancement of the performance of the voltage controller. …”
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2958
Mental health disorders among children with special health needs: A population-based cohort study using linked administrative data from Manitoba, Canada.
Published 2025-01-01“…<h4>Objective</h4>An estimated 15-22% of Canadian kindergarten-age children have a special health need (SHN), defined as a clinical diagnosis, a functional need requiring special accommodation at school, or a health condition leading to increased needs. …”
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2959
Research progress on high-entropy alloys for extreme loading environments
Published 2024-10-01“…Additionally,tailored optimization approaches should be implemented for distinct advantageous systems and phase structures,particularly those capable of activating dislocation movements,twinning,phase transformations and incorporating novel processing methodologies such as additive manufacturing. Finally,conducting more realistic simulation experiments that closely replicate extreme environments along with generating relevant engineering data are vital steps toward accelerating the practical application of HEAs in challenging settings.…”
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2960
Digital Twin-Based Technical Research on Comprehensive Gear Fault Diagnosis and Structural Performance Evaluation
Published 2025-04-01“…Taking the QPZZ-ii gearbox test bed as the physical entity, the research establishes a five-layer architecture: functional service layer, software support layer, model integration layer, data-driven layer, and digital twin layer, forming a closed-loop feedback mechanism. …”
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