A risk prediction model for poor joint function recovery after ankle fracture surgery based on interpretable machine learning by Congyang Li, Chenggang Wang, Jiru Zhang, Wenjun Zheng, Jing Shi, Li Li, Xuezhi Shi

“…SHAP analysis showed that functional exercise compliance, combined ligament injury, and open fracture accounted for the largest proportion of SHAP values and were the most important influencing factors.ConclusionThrough evaluation and comparison of the developed models, the lasso-stacking model demonstrated the best performance and is more suitable for predicting joint function recovery after ankle surgery. …”
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The principle of direct and negative feedback regulation of endocrine functions and the possibility of using polarization biomedical optic methods in the diagnosis of nodular goite... by Yu.Ye. Rohovyi, O.V. Bilookyi, O.H. Ushenko, V.V. Bilookyi

“…Violation of the principles of direct and ne­gative feedback regulation of endocrine functions leads to nodular goiter. The structure and quantitative changes of thyroid gland can be assessed more informatively and accurately by polarization biomedi­cal optics. …”
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The Effects of Indirect and Direct Modulation of Endocannabinoid System Function on Anxiety-Related Behavior in Mice Assessed in the Elevated Plus Maze Test by Marta Kruk-Slomka, Agnieszka Dzik, Grazyna Biala

“…In particular, the pharmacological indirect manipulation of ECS functions is able to elicit promising anxiolytic effects. …”
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Predictors of chronic pain and level of physical function in total knee arthroplasty: a protocol for a systematic review and meta-analysis by Jens Ivar Brox, Christopher James Rose, Anners Lerdal, Øystein Skare, Unni Olsen, Maren Falch Lindberg, Eva Marie-Louise Denison, Caryl Lynn Gay, Arild Aamodt, Ove Furnes, Kathryn A Lee

“…There is a need to review more current literature with updated methodology that addresses the limitations of earlier systematic reviews and meta-analyses. …”
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Magnaporthe Rab5 homologs show distinct functions in nerve growth factor (NGF)-mediated neurite outgrowth and cell differentiation by Yao-yao QI, Zhi-min LIANG, Jie ZHOU, Zong-hua WANG, Guo-dong LU, Guang-pu LI

“…It was reported that endogenous Rab5 function may need to be suppressed during NGF-induced neurite outgrowth and cell differentiation. …”
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Effects of individualized resistance training prescription with heart rate variability on muscle strength, muscle size and functional performance in older women by Diego Bittencourt, Ramon Martins de Oliveira, Deivid Gomes da Silva, João Guilherme Almeida Bergamasco, Marcelo de Castro Cesar, Daniela Godoi Jacomassi, Júlio Benvenutti Bueno de Camargo, J. Derek Kingsley, Cleiton Augusto Libardi

“…IntroductionThis study aimed to investigate whether individualizing autonomic recovery periods between resistance training (RT) sessions (IND) using heart rate variability (HRV), measured by the root mean square of successive R-R interval differences (RMSSD), would lead to greater and more consistent improvements in muscle strength, muscle mass, and functional performance in older women compared to a fixed recovery protocol (FIX).MethodsTwenty-one older women (age 66.0 ± 5.0 years old) were randomized into two different protocols (IND: n = 11; FIX: n = 10) and completed 7 weeks of RT. …”
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Exploring Floristic Diversity, Propagation Patterns, and Plant Functions in Domestic Gardens across Urban Planning Gradient in Lubumbashi, DR Congo by Yannick Useni Sikuzani, Bernard Kisangani Kalonda, Médard Mpanda Mukenza, Jonas Yona Mleci, Alex Mpibwe Kalenga, François Malaisse, Jan Bogaert

“…Rectangular gardens dominate in unplanned areas, while planned neighborhoods feature more intentional landscaping elements, such as flowerbeds and hedges. …”
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Tofacitinib downregulates JAK1 and JAK3 on human intestinal monocytes and macrophages without affecting dendritic cells phenotype or function by Elisa Arribas-Rodríguez, Ángel De Prado, Beatriz de Andrés, Benito Velayos, Jesús Barrio, Alejandro Romero, Francisco Javier García-Alonso, Álvaro Martín-Muñoz, José A. Garrote, Eduardo Arranz, Luis Fernández-Salazar, David Bernardo

“…Tofacitinib did not modulate the phenotype or function of human intestinal cDC. Conclussion: Tofacitinib does not modulate the phenotype and function of human intestinal cDC in UC. …”
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Comparative Effects of Hold Relax Technique and Mulligan Mobilization on Pain, Range of Motion and Function in Post Operative Knee Joint -RCT by Inbesat Fatima, Nosheen Manzoor, Aisha Waseem, Hina Manzoor

“…Many treatment techniques have been used to treat the pain, knee stiffness and functional mobility. Mulligan’s mobilization and hold relax technique was also used to treat pain, increase range of motion and functional mobility of knee joint. …”
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Relationships among cortical activation, cognition, and blood biomarkers in two types of dementia determined using functional near-infrared spectroscopy by Nairong Ruan, Nairong Ruan, Ming Liang, Ming Liang, Yuehong Liu, Xi Mei, Chengying Zheng

“…Brain function was assessed using a verbal fluency task (VFT). …”
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Solving the shortest path Problem in an interval-valued Neutrosophic Pythagorean environment using an enhanced A* search algorithm by Prasanta Kumar Raut, Sakya Singh Satapathy, Siva Prasad Behera, Said Broumi, Ajay Kumar Sahoo

“…These sets provide a more flexible way to capture uncertainty by allowing the values of nodes in the graph to vary within certain intervals rather than having fixed values. …”
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Yeast as a model system to study metabolic impact of selenium compounds by Enrique Herrero, Ralf Erik Wellinger

“…Inorganic Se forms such as selenate or selenite (the two more abundant forms in nature) can be toxic in Saccharomyces cerevisiae cells, which constitute an adequate model to study such toxicity at the molecular level and the functions participating in protection against Se compounds. …”
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The Influence of Acute Stress on Brain Dynamics During Task Switching Activities by Chin-Teng Lin, Jung-Tai King, Jhe-Wei Fan, Abhishek Appaji, Mukesh Prasad

“…One possible explanation for these results may be that the participants changed their strategy in relation to executive functions during stressful conditions by paying more attention which resulted in a higher working memory capacity which enhanced performance during the task switching.…”
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The Cognitive Correlates of Obsessive-Compulsive Disorder: The Predictive Role of Looming Maladaptive Style, Executive Function, Thought-Action Fusion and Metacognition by Maryam Koosheshi, Rahim Yousefi, Ladan Vaghef

“…Literature indicates that individuals with high cognitive threat magnification are more susceptible to anxiety in stressful life events compared to those without this predisposition. …”
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Additive manufacturing toward 2D and 3D freeform lattices with conforming compliant bi-/multi-stable tiles by Gershon Elber

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Method of thromboembolism prediction in advanced atherosclerosis by A. V. Bykov

“…Due to difficulties of separating more heterogeneous groups with a small sample, RP was synthesized according to the atherosclerosis severity classification using SC technology. …”
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Comparative Genomic Analysis of COMT Family Genes in Three <i>Vitis</i> Species Reveals Evolutionary Relationships and Functional Divergence by Yashi Liu, Zhiyuan Bian, Shan Jiang, Xiao Wang, Lin Jiao, Yun Shao, Chengmei Ma, Mingyu Chu

“…To further investigate the function of COMT in grapevine, a total of 124 <i>COMT</i> family genes were identified from three <i>Vitis</i> species in this study, namely Pinot noir (<i>Vitis vinifera</i> L.), <i>Vitis amurensis</i>, and <i>Vitis riparia</i>. …”
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Variability in grain, flour, functional properties and protein profiling in newly developed wheat genotypes grown in temperate climate of Western Himalayas by Taha Mukhtar, Abida Jabeen, Syed Zameer Hussain, Raashid Ahmad Siddiqi, Shabir H. Wani, Anju Mahendru-Singh, Tawheed Amin, Quraazah A. Amin, Mohmad Sayeed Bhat

“…These wheat genotypes were studied for their functional, structural and protein profiling characteristics as per the approved AACC and AOAC standard methods of analysis.ResultsThe various physical parameters varied significantly (p ≤ 0.05) between wheat genotypes. …”
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SARS-CoV-2 nsp13, nsp14, nsp15 and orf6 function as potent interferon antagonists by Chun-Kit Yuen, Joy-Yan Lam, Wan-Man Wong, Long-Fung Mak, Xiaohui Wang, Hin Chu, Jian-Piao Cai, Dong-Yan Jin, Kelvin Kai-Wang To, Jasper Fuk-Woo Chan, Kwok-Yung Yuen, Kin-Hang Kok

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Improved functional outcomes and cost benefits of door-to-needle time under 30 min in acute ischemic stroke: an observational study by Jia Dong James Wang, Ying-Qiu Dong, Joshua Y. P. Yeo, Kevin Soon Hwee Teo, Shiyang Ng, Mingxue Jing, Bernard P. L. Chan, Leonard L. L. Yeo, Magdalene L. J. Chia, Louis Widjaja, Lily Y. H. Wong, Pamela Lim, Shikha Kumari, Diarmuid Murphy, Hock-Luen Teoh, Benjamin Y. Q. Tan

“…They also experienced 4-day shorter length of stay (LoS) until rehabilitation (p = 0.005) and 22.7% reduction in total hospitalization costs (p = 0.004).ConclusionsThis study suggests that DTN time of ≤ 30 min is associated with improved functional outcomes and significant cost benefits, supporting consideration of this more aggressive target for acute stroke units. …”
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