Cbf11 and Mga2 function together to activate transcription of lipid metabolism genes and promote mitotic fidelity in fission yeast. by Anna Marešová, Michaela Grulyová, Miluše Hradilová, Viacheslav Zemlianski, Jarmila Princová, Martin Převorovský

“…Despite sharing a common set of target genes, little was known about their functional relationship. This study reveals that Cbf11 and Mga2 function together in the same regulatory pathway, critical for both lipid metabolism and mitotic fidelity. …”
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Fibrinolytic Activity and Platelet Function in Subjects with Obstructive Sleep Apnoea and a Patent Foramen Ovale: Is There an Option for Prevention of Ischaemic Stroke? by Monica Reggiani, Vesa Karttunen, Ulla Wartiovaara-Kautto, Asko Riutta, Shinichiro Uchiyama, Matti Hillbom

“…We hypothesize that subjects having both OSA and PFO may develop a more severe prothrombotic state during sleep than those having either OSA or PFO alone.…”
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Delineating the functional activity of antibodies with cross-reactivity to SARS-CoV-2, SARS-CoV-1 and related sarbecoviruses. by Felicitas Ruiz, William B Foreman, Michelle Lilly, Viren A Baharani, Delphine M Depierreux, Vrasha Chohan, Ashley L Taylor, Jamie Guenthoer, Duncan Ralph, Frederick A Matsen Iv, Helen Y Chu, Paul D Bieniasz, Marceline Côté, Tyler N Starr, Julie Overbaugh

“…C68.61, which targets a conserved RBD class 5 epitope, did not select for escape variants of SARS-CoV-2 or SARS-CoV-1 in culture nor have predicted escape variants among circulating SARS-CoV-2 strains, suggesting this epitope is functionally constrained. We identified 11 additional SARS-CoV-2/SARS-CoV-1 cross-reactive antibodies that target the more sequence conserved class 4 and class 5 epitopes within RBD that show activity against a subset of diverse sarbecoviruses with one antibody binding every single sarbecovirus RBD tested. …”
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Cognitive function changes during a course of electroconvulsive therapy in patients with various psychiatric illnesses: A prospective observational study by Harita Patel, Parth Patel, Roshani Patel, Nilesh Kanaujiya, Kalpesh Chandrani, Yogesh Murugan

“…After the third ECT session, there was a significant improvement in the naming domain (P = 0.003) and a trend towards improvement in overall cognitive function (P = 0.075). Patients with schizophrenia and bipolar disorder showed more significant improvements in cognitive function compared to those with other diagnoses. …”
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The extended role of carrion: Insect consumption and hair taking at fox carcasses by Daniel Redondo-Gómez, José M. Gil-Sánchez, Moisés Gonzálvez, Carlos Martínez-Carrasco, Esther Sebastián-González, Lidia Rosell, Pablo Jiménez-Nájar, José A. Sánchez-Zapata, Daniel Martín-Vega, Marcos Moleón

“…Scavenging has been profusely studied in the last decades. However, carrion is more than a direct source of food for scavengers and decomposers, as it may provide many non-scavenging ecological functions. …”
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Agricultural Output and Economic Growth Nexus: A VECM Approach on Bangladesh by Zobayer Ahmed, Mohammad Mizanur Rahman, Masud Pervez, Muhammad Salah Uddin

“…The research applies the impulse response function and variance decomposition where in both cases, the result implies that the agricultural output is much more significant on economic growth than industrial output, meaning that to be a sustainable economy, the agriculture sector cannot be ignored. …”
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Towards delineating functions within the fasciola secreted cathepsin l protease family by integrating in vivo based sub-proteomics and phylogenetics. by Russell M Morphew, Hazel A Wright, E James Lacourse, Joanne Porter, John Barrett, Debra J Woods, Peter M Brophy

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Spatiotemporal effects of landscape structure on the trade-offs and synergies among ecosystem service functions in Yangtze River Economic Belt, China by Yao Yao, Yuanyuan Yang

“…Abstract Effective landscape management is vital for maximizing the availability of ecosystem service functions (ESF). However, how landscape pattern simultaneously affects multiple ESF across time and space, specifically regarding changes in their relationships, has not been comprehensively evaluated. …”
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Role of receptor activity modifying protein 1 in function of the calcium sensing receptor in the human TT thyroid carcinoma cell line. by Aditya J Desai, David J Roberts, Gareth O Richards, Timothy M Skerry

“…Furthermore, we show that normal RAMP1 function is required for intracellular responses to ligands. …”
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Effectiveness of Computerized and Traditional Cognitive Interventions in improving the Cognitive Functions of Iranian Older Adults: A Systematic Review and Meta-Analysis by Fateme Gheysari, Mehrdad Mazaheri

“…The present study aims to review the studies on the effect of computerized and traditional cognitive interventions on the cognitive functions of healthy older adults, those with mild cognitive impairment, or Alzheimer’s disease in Iran. …”
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Results of functioning of the Federal databank of radiation doses to the population of the Russian Federation due to natural sources of ionizing radiation in 2022–2024 by T. A. Kormanovskaya

“…The paper presents results of analysis of data accumulated during 2022–2024 in the Federal databank of radiation doses to the public from exposure to natural and technologically enhanced background radiation, which functions within the framework of the Unified State System for Monitoring and Accounting for Individual Doses of Radiation to the Citizens. …”
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Multimorbidity combinations and their association with functional disabilities among Indian older adults: evidence from Longitudinal Ageing Study in India (LASI) by Laxmi Kant Dwivedi, Manish Kumar, Neha Kumari, Srei Chanda

“…The estimated PAFs of the group 1 (hypertension and HDS), group 3 (hypertension and arthritis) and group 4 (arthritis and HDS) for ADL-IADL disability were 22.5% (19.2–25.5), 21.6% (18.7–24.4) and 23.5% (20.6–26.3), respectively.Conclusion The findings from this study underscore the importance of addressing the morbidity combinations which are more disabling than the others in older adults. Understanding the somatic and psychological relevance of the morbidities in functional health is necessary and can help reduce disabilities among older adults.…”
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Soil Bacteria in Archaeology: What Could Rank Abundance Functions Tell Us About Ancient Human Impacts on Microbial Communities? by J. Michael Köhler, Linda Ehrhardt, P. Mike Günther, Jialan Cao

“…Here, the formation of characteristic rank order functions of bacterial abundance is investigated by modelling the dynamics of soil bacterial communities, assuming a succession of different bacterial populations that grow rapidly and decay more slowly. …”
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Functional differences between PD-1+ and PD-1- CD4+ effector T cells in healthy donors and patients with glioblastoma multiforme. by Brittany A Goods, Amanda L Hernandez, Daniel E Lowther, Liliana E Lucca, Benjamin A Lerner, Murat Gunel, Khadir Raddassi, Vlad Coric, David A Hafler, J Christopher Love

“…Enrichment of these gene sets in tumor suggests a more metabolically active cell state with signaling through other co-receptors. …”
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A percolation theory analysis of continuous functional paths in protein sequence space affirms previous insights on the optimization of proteins for adaptability. by Brian J Miller

“…Natural selection could direct a mutating coding region in DNA along a continuous functional path (CFP), so a new protein could arise far more easily than if a coding region were randomly mutating without any constraints. …”
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Functional Studies on the <i>LiAG1</i> Gene of <i>Lilium</i> ‘Ice Pink Queen’ in Flower Development by Lili Xue, Jingqi Dai, Ruyu Fu, Nana Wu, Jiaxuan Yu, Jie Dong, Tao Yang, Jinping Fan

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Enhancing Global Cognition and Executive Functions Through Water-Based Exercise in Mild Cognitive Impairment: A Randomized Controlled Trial by Sutaya Meekum, Kornanong Yuenyongchaiwat, Nongnuch Luangpon, Piyapa Keawutan, Patcharee Kooncumchoo

“…These findings suggest that water-based exercise combined with cognitive training enhances cognitive functions more effectively than exercise alone in older adults with MCI.…”
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Luteolin, a common flavone in vegetables, acts as a hormetin possessing neurotrophic function: signaling mediated by inducing mitochondrial stress by Alex Xiong Gao, Tracy Chenxi Xia, Maggie Suisui Guo, Gary Kawing Yuen, Kevin Qiyun Wu, Tina Tingxia Dong, Karl Wah-Keung Tsim

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Short- and long-term effects of microwave ablation and radiofrequency ablation on nodule volume and thyroid function in patients with benign thyroid nodules by HAN Xiaojun, GUO Daoning, WANG Ning

“…"<b>Objective</b> To explore the short- and long-term effects of microwave ablation (MWA) and radiofrequency ablation (RFA) on thyroid nodule volume and thyroid function in patients with benign thyroid nodules (BTN). …”
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Density functional calculations of La(H2O)103+ and Mg(H2O)62+ adsorption on kaolinite surfaces by ZHANG Xuyong, MAO Song, KE Baolin, ZHANG Tiebin, ZHANG Dongmei, WU Fang

“…By drawing on the density functional theory, our calculations show the stable configurations of La3+ and Mg2+ hydrated ions are La(H2O)103+ and Mg(H2O)62+. …”
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