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Selective Modulation of Osteoclast Function by <i>Bothrops moojeni</i> Venom and Its Fractions: Implications for Therapeutic Targeting in Bone Diseases
Published 2025-03-01“…It influences vital cellular signaling pathways, notably through FNIP1 and FNIP2, essential for OC differentiation and function. This suggests a more targeted therapeutic approach with potentially fewer off-target effects. …”
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4003
A Virtual Reality Force Control Training System on Brain Activation: Functional Near-Infrared Spectroscopy (fNIRS) Study
Published 2025-07-01“…The addition of a force control component to the hand tracking of these systems could make them even more effective at improving or restoring hand function, as the majority of activities of daily living require a degree of force control. …”
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4004
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4005
Evaluating the role of AI-simulated patients compared with peer-to-peer learning models in the enhancement of medical education: is it beyond theoretical functionality?
Published 2025-06-01“…Compared with peer-to-peer learning, SIMPAT was perceived as more time-efficient, because, traditionally, one peer within a pair had to be the ‘patient actor’. …”
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4006
Development and evaluation of folic acid conjugated curcumin-loaded functionalized multiwalled carbon nanotubes for enhanced efficacy in ovarian cancer treatment
Published 2025-04-01“…A dispersion study revealed the presence of functional groups on the outermost surface of both the functionalized MWCNT as well as formulations increased their resilience via converting the hydrophobic MWCNT surface to hydrophilic property. …”
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4007
A Coupling Electromechanical Inhomogeneous Cell-Based Smoothed Finite Element Method for Dynamic Analysis of Functionally Graded Piezoelectric Beams
Published 2019-01-01“…To accurately simulate the continuous property change of functionally graded piezoelectric materials (FGPMs) and overcome the overstiffness of the finite element method (FEM), we present an electromechanical inhomogeneous cell-based smoothed FEM (ISFEM) of FGPMs. …”
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4008
The zeros of az2J″ν(z)+bzJ′ν(z)+cJν(z) as functions of order
Published 1992-01-01“…The present paper, by using a different kind of analysis, re-obtains these conclusions as a special case of a more general result concerning the positive zeros of the function az2J″ν(z)+bzJ′ν(z)+cJν(z). …”
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4009
Study of the Functional State of the Proximal Renal Tubules in Patients with Asymptomatic Chronic Heart Failure in Dyslipidemia and its Correction with Simvastatin Treatment
Published 2020-12-01“…The main group included patients with a total serum cholesterol level of more than 6.0 mmol/l, a BMI level of more than 30 kg/m2, and who had not previously taken statins. …”
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4010
Proteins derived from Bombyx batryticatus utilizing variable ultrasound powers: Evaluation of structural attributes, functional characteristics, and antioxidant capacities
Published 2025-08-01“…The current investigation evaluated the impact of diverse ultrasound power levels (0, 120, 200, 320, 400, and 520 W) on the structural, functional, and antioxidant potentials of proteins derived from Bombyx batryticatus (PBB). …”
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4011
Midpoint-type integral inequalities for (s, m)-convex functions in the third sense involving Caputo fractional derivatives and Caputo–Fabrizio integrals
Published 2024-12-01“…This article utilized [Formula: see text]-convex function in the third sense to generalized midpoint-type integral inequalities which give more sharp inequalities.…”
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4012
The N-Terminal GYPSY Motif Is Required for Pilin-Specific Sortase SrtC1 Functionality in Lactobacillus rhamnosus Strain GG.
Published 2016-01-01“…Substitutions of some of the GYPSY residues, and more specifically the proline residue, were found to have a direct impact on the degree of piliation of Lb. rhamnosus GG. …”
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4013
Acoustic modelling of surface sources. Part II. Piston model, asymmetrical function of vibration velocity, discretizing error, axisymmetrical problem
Published 2014-01-01“…Its variation, as a function of vibration velocity or position of the vibrating surface in the baffle or nondimensional wave number, is more regular than the variation of uniform distance.…”
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The pancreatic tumor microenvironment of treatment-naïve patients causes a functional shift in γδ T cells, impairing their anti-tumoral defense
Published 2025-12-01“…Circulating Vδ1 T cells exhibit a terminal effector memory phenotype (TEMRA) more than Vδ2 T cells. Interestingly, Vδ1 and Vδ2 T cells appear to be more prevalent at different stages of tumor development. …”
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4016
Automated extraction of functional biomarkers of verbal and ambulatory ability from multi-institutional clinical notes using large language models
Published 2025-04-01“…Future studies are needed to extend this methodology to additional populations and to demonstrate more granular functional data classification.…”
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4017
Association of over-the-counter mouthwash use with markers of nitric oxide metabolism, inflammation, and endothelial function—a cross-sectional study
Published 2025-01-01“…Robust Gamma regression with log-link function, Spearman correlations and partial correlations adjusted for covariates were used for the analysis.ResultsUsing OTC mouthwash twice a day or more was significantly associated with lower serum nitrite levels compared to less frequent use (β = −0.357, 95% CI: −0.650, −0.064), but not with other markers of inflammation and endothelial function. …”
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Clinical and functional evaluation of intramyocardial implantation of autologous bone marrow cells treated with erythropoietinduring the CAD surgery (6-month results)
Published 2019-01-01“…Six months after the operation, there was a more pronounced decrease in angina pectoris (CCS) in the main group compared to the control group, also we revealed a 6-minute walk test scores improvement. …”
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4019
Subjective Evaluation of Three Headphone-Based Virtual Sound Source Positioning Methods Including Differential Head-Related Transfer Function
Published 2016-03-01“…This paper analyses the performance of Differential Head-Related Transfer Function (DHRTF), an alternative transfer function for headphone-based virtual sound source positioning within a horizontal plane. …”
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Stochastic Fracture Analysis Using Scaled Boundary Finite Element Methods Accelerated by Proper Orthogonal Decomposition and Radial Basis Functions
Published 2021-01-01“…It is also found that the larger the scale of the problem, the more advantageous the proposed method is.…”
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