Antioxidant functionalized double-net/TA dynamic hydrogel promotes cartilage regeneration through stabilization of chondrocyte phenotype by Xu Wu, Honglei Wang, Chenlong Li, Yaying Zhu, Qixuan Wang, Tianyu Zhang, Yaoyao Fu, Aijuan He

“…The DN-TA hydrogel effectively preserved the chondrocyte phenotype by activating HIF-1 signaling pathway and reducing ROS (reactive oxygen species).Furthermore, after 8/12 weeks of subcutaneous implantation, the DN-TA scaffold significantly enhanced in vivo cartilage regeneration, as evidenced by increased extracellular matrix deposition and more mature cartilage formation. Collectively, our study demonstrates that reducing aerobic metabolism helps stabilize the chondrocyte phenotype and promotes functional cartilage regeneration. …”
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A longitudinal panel study exploring associations of urinary phthalate metabolites mixture with renal function in Chinese children by Yudan Zheng, Lei Zhao, Yuming Zheng, Wenya Bai, Xuefeng Lai, Liangle Yang, Xiaomin Zhang, Miao Liu

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Auricular acupoint therapy for functional gastrointestinal disorders: a systematic review and meta-analysis of randomized clinical trials by Meng-Yuan Shen, Ze-Jiong Li, Shu-Han Wang, Tian-Chen Lin, Qin-Yi Lou, Shan Liu, Dan-Dan Feng, Dong-Dong Yang, Chen-Juan Wang, Zhe-Kai Ying, Rong Zhou, Jian-Nong Wu

“…IntroductionThis study aims to conduct a systematic review and meta-analysis of randomized controlled trials to evaluate the efficacy and safety of auricular acupoint therapy (AAT) for functional gastrointestinal disorders (FGIDs).MethodsWe conducted a thorough search across eight databases, including PubMed, EMBASE, Web of Science, the Cochrane Library, CNKI, Wanfang, VIP, and CBM. …”
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Myocardial impairment in rheumatoid arthritis patients with normal left ventricular function: findings from speckle tracking echocardiography by Rim Dhahri, Mahfoudhi Houaida, Ismail Dergaa, Lobna Ben Ammar, Halil İbrahim Ceylan, Youssef Ben Abderrazek, Insaf Fenniche, Sarra Chenik, Wafa Fehri, Raul Ioan Muntean, Imène Gharsallah

“…Traditional echocardiogram frequently overlooks early myocardial failure, necessitating more sensitive imaging modalities, such as speckle tracking echocardiography (STE), to effectively diagnose subclinical left ventricular systolic dysfunction (LVSD). …”
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Metagenomic Analysis Identifies Sex‐Related Gut Microbial Functions and Bacterial Taxa Associated With Skeletal Muscle Mass by Hang A. Park, Joohon Sung, Yoosoo Chang, Seungho Ryu, Kyung Jae Yoon, Hyung‐Lae Kim, Han‐Na Kim

“…ABSTRACT Background This study aimed to explore the association between gut microbiota functional profiles and skeletal muscle mass, focusing on sex‐specific differences in a population under 65 years of age. …”
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Effects of Physical Exercise Breaks on Executive Function in a Simulated Classroom Setting: Uncovering a Window into the Brain by Qian Yu, Zhihao Zhang, Sebastian Ludyga, Kirk I. Erickson, Boris Cheval, Meijun Hou, Dominika M. Pindus, Charles H. Hillman, Arthur F. Kramer, Ryan S. Falck, Teresa Liu‐Ambrose, Jin Kuang, Sean P. Mullen, Keita Kamijo, Toru Ishihara, David A. Raichlen, Matthew Heath, David Moreau, André O. Werneck, Fabian Herold, Liye Zou

“…MIC and VIC conditions produced pre‐to‐post‐intervention increases in CRAE and CRVE (β = 4.46, 6.34), frontal activation, and resting‐state and task‐state causal density (β = 0.37, 0.06) (ps < 0.05) compared to SIT; VIC was more beneficial for executive function and neurobiological parameters. …”
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Volume contracted state, mortality and functional outcomes in patients with acute ischaemic stroke due to large vessel occlusion by Risheng Xu, Max Wintermark, Gregory W Albers, Jeremy J Heit, Adam A Dmytriw, Adrien Guenego, Yasmin Aziz, Kambiz Nael, Benjamin Pulli, Victor Urrutia, Dhairya A Lakhani, Tobias D Faizy, Argye Hillis, Vivek Yedavalli, Dylan Wolman, Licia P Luna, Elisabeth B Marsh, Hamza Adel Salim, Janet Mei, Vaibhav Vagal, Aakanksha Sriwastwa, Raf Llinas, Hanzhang Lu, Mona N Bahouth

“…Age and initial stroke severity were more strongly associated with long-term functional outcomes.Conclusions VCS is associated with higher odds of 90-day mortality in patients with LVO-AIS but not with unfavourable functional outcomes. …”
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Pragmatic questionnaire-based evaluation of auditory function in individuals with major neurocognitive disorders and hearing loss in diverse contexts by Panagiotis Alexopoulos, Panagiotis Alexopoulos, Panagiotis Alexopoulos, Panagiotis Alexopoulos, Antonios Alexandros Demertzis, Panagiotis Biris, Polychronis Economou, Eric Frison, Piers Dawes, Iracema Leroi

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A functionally tunable magnetic nanochains platform for N-glycoproteomic analysis of extracellular vesicles from ultratrace biofluids by Mingyang Li, Xiaorong Song, Haixia Tu, Jie Sun, Yuanyuan Deng, Bing Wang, Yuhan Cai, Yulian Wang, Bin Li, Yue Wang, Xiangzheng Zhang, Dong Wei, Xiaoyu Yang, Yueshuai Guo, Xiang Li, Jie Gu, Jie Ni, Yifan Zhou, Zhongze Gu, Zhuoying Xie, Yan Li, Xuejiang Guo

“…The streamlined EVGpro platform identified up to 17 times more EV glycoproteins than ultracentrifugation across seven biofluids, profiling 398 EV glycoproteins from just 1 μL tear. …”
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Impact of COVID-19 on functional, cognitive, neuropsychiatric, and health-related outcomes in patients with dementia: A systematic review by Lucia Crivelli, Andrea Winkler, Greta Keller, Simone Beretta, Ismael Luis Calandri, Wouter De Groote, Arianna Fornari, Jennifer Frontera, Miia Kivipelto, Ana Sabsil Lopez-Rocha, Francesca Mangialasche, Daniel Munblit, Katie Palmer, Alla Guekht, Ricardo Allegri

“…Background: This systematic review analyzes the impact of COVID-19 on dementia patients' functional, cognitive, neuropsychiatric, and health related outcomes. …”
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Multimodal Fusion Framework for Urban functional zone change detection using Remote Sensing and Social Sensing Data by B. Fang, B. Fang, B. Fang, B. Fang, X. Chen, X. Chen, X. Chen, X. Chen, H. Chen, H. Chen, Z. Xiang, Z. Xiang, B. Hu, B. Hu, Z. Hu, Z. Hu, Z. Hu, Z. Hu, W. Tu, W. Tu, W. Tu, W. Tu

“…For the RS-branch, RS imagery provides detailed spatial information about urban transformations; for the MP-branch, MP data as a typical social sensing data captures temporal patterns in human mobility, offering insights into functional shifts in urban spaces. By fusing these two complementary modalities, our approach allows for a more nuanced detection of urban functional zone changes. …”
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Human hair follicle-derived mesenchymal stem cells improve ovarian function in cyclophosphamide-induced POF mice by Jinhua Mo, Hong Hu, Pengdong Li, Yang Ye, Wanle Chen, Lei Chen, Jing Qiao, Xiaoying Zhao, Qiuxia Yan, Cairong Chen

“…Furthermore, those effects was more significant in P–H group than in P–U group (p < 0.05). …”
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Resistance and Impact Training During Weight Loss Improves Physical Function and Body Composition in Older Adults With Obesity by Jakub Mesinovic, Anoohya Gandham, Mavil May Cervo, Paul Jansons, Costas Glavas, Michael Braude, Juan Pena Rodriguez, Barbora De Courten, Ayse Zengin, Belinda R. Beck, Peter R. Ebeling, David Scott

“…Changes in physical function (primary outcome: gait speed) and body composition were compared between groups. …”
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Effect of rituximab on the manifestations of activity and pulmonary function in patients with systemic sclerosis: one-year follow-up evaluation by L. P. Ananyeva, O. A. Koneva, O. V. Desinova, L. A. Garzanova, S. I. Glukhova, M. N. Starovoitova, O. B. Ovsyannikova, A. V. Volkov, A. P. Aleksankin, E. L. Nasonov

“…We were the first to show the association of positive changes in the measures of pulmonary function tests with the dose of RTM.…”
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Perioperative, Oncological, and Functional Outcomes of New Multiport Robotic Platforms in Urology: A Systematic Review and Meta-analysis by Giuseppe Reitano, Arianna Tumminello, Umar Ghaffar, Giorgio Saggionetto, Alessandra Taverna, Francesco Mangiacavallo, Mohamed E. Ahmed, Spyridon P. Basourakos, Filippo Carletti, Davide Minardi, Massimo Iafrate, Alessandro Morlacco, Giovanni Betto, R. Jeffrey Karnes, Fabrizio Dal Moro, Fabio Zattoni, Giacomo Novara

“…Background and objective: Robot-assisted surgery (RAS) has steadily become more prevalent in urology. The Da Vinci multiport surgical robot (DVM-SR) continues to lead the field. …”
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Positive Properties of Green’s Function for Fractional Dirichlet Boundary Value Problem with a Perturbation Term and Its Applications by Yongqing Wang

“…The existence of positive solutions is determined under a more general condition, <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><mi mathvariant="script">F</mi><mo>(</mo><mi>ξ</mi><mo>,</mo><mi mathvariant="normal">x</mi><mo>)</mo><mo>≥</mo><mo>−</mo><mi mathvariant="normal">b</mi><mo>(</mo><mi>ξ</mi><mo>)</mo><mi mathvariant="normal">x</mi><mo>−</mo><mi mathvariant="normal">e</mi><mo>(</mo><mi>ξ</mi><mo>)</mo></mrow></semantics></math></inline-formula>, where <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><mi mathvariant="normal">b</mi><mrow><mo>(</mo><mi>ξ</mi><mo>)</mo></mrow><mo>,</mo><mi mathvariant="normal">e</mi><mrow><mo>(</mo><mi>ξ</mi><mo>)</mo></mrow><mo>∈</mo><msup><mi>L</mi><mn>1</mn></msup><mrow><mo>[</mo><mn>0</mn><mo>,</mo><mn>1</mn><mo>]</mo></mrow></mrow></semantics></math></inline-formula> are non-negative functions. …”
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PO20 | Impact of endovascular treatment on functional outcome in ischemic stroke: a real-world retrospective study

“…This study evaluated clinical and procedural predictors of functional outcomes at discharge and 90 days in patients with LVO IS treated with MT, with or without IVT, in a real-world setting. …”
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Assessment of photoreceptor recovery and visual function utilizing adaptive optics and microperimetry in patients with surgically closed macular holes by Yuanyuan Liu, Xueli Yang, Wei Zhou, Jinguo Yu, Song Chen, Tiangeng He, Caiyun You, Xiangda Meng, Mengyu Liao, Yi Lei, Hua Yan

“…Background: This study investigated the association between photoreceptor structural restoration and visual function outcomes in patients undergoing surgery for closed macular holes (MHs). …”
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Neurodevelopmental Tics with Co-Morbid Functional Tic-like Behaviors: Diagnostic Challenges of a Complex Tourette Syndrome Phenotype by Andrea Eugenio Cavanna, Virginia Caimi, Elisa Capriolo, Matteo Marinoni, Gabriele Arienti, Anna Riva, Renata Nacinovich, Stefano Seri

“…<b>Results</b>: Complex vocal tics (<i>p</i> < 0.001), including coprolalia (<i>p</i> = 0.002), and self-injurious behaviors (<i>p</i> < 0.001), often as part of tic attacks (<i>p</i> < 0.001), were confirmed to be more commonly reported by the group of patients with TS + FTBs, who were also more likely to present with anxiety (<i>p</i> < 0.001) and other functional neurological symptoms (<i>p</i> < 0.001) compared to patients with TS. …”
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Efficient estimation in ZIP models with applications to count data by Nurul N. Mohamad, Ibrahim Mohamed, Ng Kok-Haur, Mohd S. Yahya

“…Results show that the estimators derived from QEF method, which uses information from combined estimating functions, is more informative than linear estimating functions (LEF) method that only uses information from component estimating functions. …”
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