Brief Video-Delivered Intervention to Reduce Anxiety and Improve Functioning in Older Veterans: Pilot Randomized Controlled Trial by Christine E Gould, Chalise Carlson, Julie L Wetherell, Mary K Goldstein, Lauren Anker, Sherry A Beaudreau

“…Measures of anxiety, depression, and functioning were obtained at baseline, week 4 (end of treatment), week 8, and week 12. …”
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Genomic ncRNAs regulating mitochondrial function in neurodegeneration: a neglected clue in the complex etiopathogenesis of multiple sclerosis by Nima Sanadgol, Mahedeh Samadi, Clara Voelz, Roghayeh Khalseh, Javad Amini, Cordian Beyer, Markus Kipp, Tim Clarner

“…Recent interest has surged around the role of inflammatory non-coding RNAs (ncRNAs) in mitochondrial function, particularly in the context of neurodegenerative diseases (NDs), where neuroinflammation is a hallmark feature. …”
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Blocking NKG2A in Echinococcus multilocularis infection partially relieves impairment of NK cell function of the host by Ayinuer Aierken, Aili Aierken, Kalibixiati Aimulajiang, Abuduaini Abulizi, Zhongdian Yuan, Chang Liu, Dalong Zhu, Hanyue Zhao, Tuerganaili Aji

“…Conclusion Our results demonstrate the involvement of NKG2A in impaired NK cell function during E. multilocularis infection in both humans and mice, suggesting that targeting NKG2A through blockade has the potential to restore NK cell function against this infection.…”
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Attributable risk factors for asymptomatic malaria and anaemia and their association with cognitive and psychomotor functions in schoolchildren of north-eastern Tanzania. by Geofrey Makenga, Vito Baraka, Filbert Francis, Daniel T R Minja, Samwel Gesase, Edna Kyaruzi, George Mtove, Swabra Nakato, Rashid Madebe, Sif R Søeborg, Kathrine H Langhoff, Helle S Hansson, Michael Alifrangis, John P A Lusingu, Jean-Pierre Van Geertruyden

“…In Africa, children aged 5 to 15 years (school age) comprises more than 50% (>339 million) of the under 19 years population, and are highly burdened by malaria and anaemia that impair cognitive development. …”
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Pain- and depression-related regional homogeneity changes in ankylosing spondylitis: a functional magnetic resonance imaging study by Kelei Hua, Peijun Wang, Bin Xia, Haiying Wang, Haiying Wang, Tianyue Wang, Jin Fang, Yi Yin, Yike Tu, Yike Tu, Guihua Jiang, Guihua Jiang

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Effect of dapagliflozin on the structural and functional properties of arterial vessels in patients with type 2 diabetes mellitus in combination with obesity by О. А. Soloviuk, R. L. Kulynych

“…However, the possible significance of dapagliflozin in the reversal of structural and functional changes in the arteries in patients with type 2 DM and obesity has not been studied enough. …”
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The relationship between cognitive function and neuropsychiatric disorders with quantitative electroencephalogram (qEEG) on long COVID syndrome patients by Yetty Ramli, Pukovisa Prawiroharjo, Winnugroho Wiratman, Eric Tenda, Nurhadi Ibrahim, Damar Susilaradeya, Abdi Reza, Jennifer Agatha, Rejoel Siagian, Hazrina Fauhan, Florencia Evelyn, Yoshikazu Ugawa, Prasandhya Yusuf

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Assessment of the Abnormalities in Chest Computed Tomography and Pulmonary Function Test in Convalescents Six Months After COVID-19 by Katarzyna Guziejko, Anna Moniuszko-Malinowska, Robert Flisiak, Piotr Czupryna, Sebastian Sołomacha, Paweł Sowa, Marlena Dubatówka, Magda Łapińska, Łukasz Kiszkiel, Łukasz Szczerbiński, Piotr Paweł Laskowski, Maciej Alimowski, Gabriela Trojan, Karol Adam Kamiński

“…The goal was to support more individualized pulmonary management of post-COVID-19 sequelae. …”
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Association of body composition and physical activity with pain and function in knee osteoarthritis patients: a cross-sectional study by Hongbo Chen, Dan li, Shaomei Shang, Wen Zeng, Mengqi Wang, Beibei Tong, Peiyuan Liu, Cui Wang

“…More skeletal muscle mass was associated with the improvement of objective function.…”
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Changing grizzly bear space use and functional connectivity in response to human disturbance in the southern Canadian Rocky Mountains by Eric C. Palm, Clayton D. Apps, Tal Avgar, Melanie Dickie, Bruce N. McLellan, Joseph M. Northrup, Michael A. Sawaya, Julie W. Turner, Jesse Whittington, Erin L. Landguth, Katherine A. Zeller, Clayton T. Lamb

“…Females generally avoided moving through towns in spring and summer, while males were more likely to do so. Additional footprints of proposed mines and expanded human settlements in a potential future scenario were predicted to further decrease functional connectivity for grizzly bears on top of prior connectivity losses from existing human disturbance. …”
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Characterization and functional evaluation of JS207, a novel bispecific antibody against human PD-1 and VEGFA by Shihua Lin, Min Hong, Jing Zhang, Wenting Zhao, Ke Li, Chun Wu, Qiuyun Yang, Yi Xiao, Lanqing Huang, Jing Wang, Aijuan Jia, Xujia Wang, Sheng Yao

“…While combining PD-1 and VEGF inhibition has shown promise in enhancing antitumor responses, co-administration of two or more monoclonal antibodies face several challenges, including distinct pharmacokinetics, complex dosing, and toxicity. …”
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Pharmacological CLK inhibition disrupts SR protein function and RNA splicing blocking cell growth and migration in TNBC by Nasi Liu, Jurjun J. S. van der Velde, Sherien Ramdjielal, Esmee Koedoot, Nila K. van Overbeek, Daisy Batenburg, Alfred C. O. Vertegaal, Bob van de Water, Sylvia E. Le Dévédec

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Novel Structure–Function Models for Estimating Retinal Ganglion Cell Count Using Pattern Electroretinography in Glaucoma Suspects by Andrew Tirsi, Isabella Tello, Timothy Foster, Rushil Kumbhani, Nicholas Leung, Samuel Potash, Derek Orshan, Celso Tello

“…The combined structure–function index (CSFI), which uses visual field and optical coherence tomography (OCT) data to estimate RGC counts, may be of limited utility in GSs. …”
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THE INFLUENCE OF HEART RATE VARIABILITY ON CLINICAL COURSE OF CHRONIC HEART FAILURE AND RENAL FUNCTION IN ATRIAL FIBRILLATION PATIENTS by E. A. Polyanskaya, S. V. Mironova, N. A. Koziolova

“…Evaluation of structural and functional condition of the left ventricle (LV) and kidneys in permanent atrial fibrillation patients (AF) with ischemic chronic heart failure (CHF) according to mean 24 hour heart rate and heart rate variability.Material and methods. …”
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Emission pattern and anti-insect function of indole from tea plant (Camellia sinensis) attacked by tea geometrids by Jianlong Li, Guotai Jian, Jiajia Qian, Jinghua Xue, Chengshun Liu, Yongxia Jia, Bo Zhou, Jinchi Tang, Jie Yang, Lanting Zeng

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Reduction of inflammatory biomarkers underlies extracellular vesicle mediated functional recovery in an aged monkey model of cortical injury by Ryan P. McCann, Bethany Bowley, Monica Pessina, Qiong Yang, Hongqi Xin, Sarah A. DeVries, Mingjin Wang, Yi Zhang, Michael Chopp, Zhenggang Zhang, Douglas L. Rosene, Douglas L. Rosene, Ella Zeldich, Ella Zeldich, Maria Medalla, Maria Medalla, Tara L. Moore, Tara L. Moore

“…Downregulation of inflammatory markers in plasma and brain tissue were positively correlated with improved functional recovery. These data suggest that MSC-EVs facilitate recovery of function after brain injury, in part, via sustained suppression of both peripheral and central pro-inflammatory signaling across recovery.…”
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Single-chain variable fragment affinity tuning can optimize anti-AML CAR-NK cell functionality by Marianna Zahurak, Ravi Varadhan, Ilias Christodoulou, Ruyan Rahnama, Jun Choe, Huilin Yang, Monika Kizerwetter, Christian Guaraca, Natalie Jordan Holl, Stamatia C Vorri, Megan Zinsky, Danielle G Jones, Nikol Garcia Espinoza, Yun-Huai Kuo, Jamie B. Spangler, Challice L. Bonifant

“…Affinity-based differences in functional activation and antitumor activity are dependent on time course and are scFv/epitope specific.…”
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Morphological, functional and biochemical differences in cardiac adaptation to endurance exercise among male and female amateur marathon runners by Zofia Lasocka-Koriat, Zofia Lasocka-Koriat, Zuzanna Lewicka-Potocka, Zuzanna Lewicka-Potocka, Anna Kaleta-Duss, Nikola Bulman, Ewelina Marciniak, Leszek Kalinowski, Leszek Kalinowski, Ewa Lewicka, Alicja Dąbrowska-Kugacka

“…Less-trained marathoners with lower VO2max values after the race showed higher levels of Gal-3 post-run (r = −0.29; p < 0.05).ConclusionMarathon running induces transient cardiac remodelling, more pronounced in male than female athletes. Structural and functional changes assessed by echocardiography correspond with biochemical alterations. …”
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Functional immune reconstitution after allogeneic hematopoietic stem cell transplantation in myeloablative and non-myeloablative conditioned patients by Patrick Terrence Brooks, Lia Minculescu, Rebecca Svanberg Teglgaard, Hans Jakob Hartling, Jose Antonio Salado-Jimena, Lone Smidstrup Friis, Brian Kornblit, Ida Schjødt, Søren Lykke Petersen, Niels Smedegaard Andersen, Susanne Dam Nielsen, Jens Lundgren, Hanne Vibeke Marquart, Lars Klingen Gjaerde, Henrik Sengeløv, Sisse Rye Ostrowski

“…A secondary study amongst MA conditioned patients further revealed that those who received fludarabine and treosulfan (n = 35) had higher T cell concentration and stimulated immune function compared to patients receiving more intense MA regimens (n = 15). …”
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Functional recovery following hospitalisation of patients diagnosed with COVID-19: a protocol for a longitudinal cohort study by Julie C Reid, Maureen Markle-Reid, Ameen Patel, Andrew P Costa, Maura Marcucci, MyLinh Duong, Connie Schumacher, Aaron Jones, Mats Junek, Marla K Beauchamp, Parminder Raina, Lauren E Griffith, Sophie Corriveau, Shariq Haider, Terence Ho, Rebecca Kruisselbrink, Hope Morrison, Natya Raghavan, Leslie Martin, Carla Girolametto

“…However, there is limited evidence on the trajectory of functional recovery in those hospitalised with COVID-19. …”
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