The CD4/CD8 ratio is associated with T lymphocyte functions in long-term virally suppressed patients with HIV by Qing Xiao, Fengting Yu, Liting Yan, Xiaojie Lao, Xuelei Liang, Hongxin Zhao, Liuyue Zhai, Zailin Yang, Xiaomei Zhang, Yao Liu, Fujie Zhang

“…Additionally, the ELR group had more inflammatory markers in CD4+ T cells. Correlation analysis revealed that the CD4/CD8 ratio was associated with multiple T cell functions, and its correlation coefficient with mitochondrial function was higher than that of CD4+ T cell count. …”
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Influence of environmental exposures on T follicular helper cell function and implications on immunity: a comparison of Bangladeshi and American children by Dana M. Van Fossen, Hyunjae Cho, Lisa E. Wagar, Jennie Z. Ma, Julie Parsonnet, Rashidul Haque, Mark M. Davis, William A. Petri

“…ABSTRACT T follicular helper (Tfh) cells are crucial for B cell activation and subsequent antibody production. This functionality is influenced by surface markers such as CD40L, a costimulatory factor which promotes B cell activation, and CD57, which is a well-known marker of senescence. …”
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Sex-Specific Changes in Cardiac Function and Electrophysiology During Progression of Adenine-Induced Chronic Kidney Disease in Mice by Valentina Dargam, Anet Sanchez, Aashiya Kolengaden, Yency Perez, Rebekah Arias, Ana M. Valentin Cabrera, Daniel Chaparro, Christopher Tarafa, Alexandra Coba, Nathan Yapaolo, Perony da Silva Nogueira, Emily A. Todd, Monique M. Williams, Lina A. Shehadeh, Joshua D. Hutcheson

“…Adenine-treated males showed more severe CKD than females. Cardiac physiology was evaluated using electrocardiogram (ECG) and echocardiogram markers. …”
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Assessment of lower urinary tract symptoms 6 weeks after delivery and the relationship of pelvic floor muscle function by Lei Zhang, Xiaoxiao Wang, Xinnan Hou, Xinrong Zhuang, Yu Wang, Xiaoqing Wang, Ye Lu

“…The relationship between the emergence of LUTS and the decline of pelvic muscle function after childbirth remains uncertain.Study designThis observational study was carried out at the Peking University First Hospital over a time span of 2019–2022. …”
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L‐Aspartic Acid with Dual Functions: An Eco‐Friendly and Affordable Choice to Accelerate High Salinity Brine Utilization by Suning Mao, Zhen Yu, Jie Chen, Yizhe Shen, Minjie Li, Chen Sun, Xiaoqing Lin, Bin Yang, Tong Chen, Qunxing Huang, Xiaodong Li, Jianhua Yan

“…Abstract L‐Aspartic acid (L‐Asp) poses a dual function, which can affect the evaporation and crystallization process of the high‐salinity brine by altering the physical or chemical properties of the salts. …”
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Functional conduction system mapping in sheep reveals Purkinje spikes in the free wall of the right ventricular outflow tract by Michiel Blok, Michiel Blok, Bram L. den Ouden, Bram L. den Ouden, Marion Kuiper, Daan R. M. G. Ophelders, Daan R. M. G. Ophelders, Monique R. M. Jongbloed, Monique R. M. Jongbloed, Stef Zeemering, Bjarke Jensen, Arne van Hunnik, Bastiaan J. Boukens, Bastiaan J. Boukens

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Enhancing cognitive function through blood flow restriction: An effective resistance exercise modality for middle-aged women by Dohyeon Lee, Kyeongho Byun, Sewon Lee

“…Purpose: Cognitive decline progresses more rapidly in women than in men, with a higher prevalence of neurodegenerative diseases observed in females. …”
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Short-term clinical and functional outcomes of distal biceps tendon fixation: all-suture vs. titanium anchors by Felix Hochberger, MD, Julian Hess, MD, Christian Konrads, MD, Tizian Heinz, MD, Ella Segatz, Maximilian Rudert, MD, Kilian List, MD

“…HOs were significantly more prevalent in the TA group (37.5% vs. 17.2%, P < .05). …”
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Functional Monitoring of Patients With Knee Osteoarthritis Based on Multidimensional Wearable Plantar Pressure Features: Cross-Sectional Study by Junan Xie, Shilin Li, Zhen Song, Lin Shu, Qing Zeng, Guozhi Huang, Yihuan Lin

“…Future work is needed to further explore and investigate the relationship between gait characteristics and functional status with more functional tests and in larger sample cohorts.…”
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Enhancing bioactive profiles of elderberry juice through yeast fermentation: a pathway to low-sugar functional beverages by Amir Shazad, Ali Zein Alabiden Tlais, Davide Gottardi, Pasquale Filannino, Francesca Patrignani, Rosalba Lanciotti, Marco Gobbetti, Raffaella Di Cagno

“…In response to the growing need for functional beverages, this study aimed to harness yeast metabolism to optimize elderberry juice fermentation, targeting sugar reduction and enrichment of bioactive compounds with enhanced functional properties. …”
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Evaluation of anatomical and functional success in canalicular laceration repair using anterior segment optical coherence tomography and dacryoscintigraphy by Çisil Erkan Pota, Özge Ekin Geçer Şerifoğlu, Aslı Çetinkaya Yaprak, Hatice Deniz İlhan, Adil Boz

“…Purpose: To assess the anatomical and functional outcomes in patients who underwent surgery for canalicular laceration and did not experience significant epiphora, and to compare these outcomes with contralateral uninjured eye. …”
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Latent Cytomegalovirus Infection Is Associated With Impaired Left Ventricular Function After ST‐Segment–Elevation Myocardial Infarction by Luke Spray, Alasdair McIntosh, Peter J. McCartney, Peter W. Macfarlane, Annette Maznyczka, Paul Welsh, Colin Berry, Ioakim Spyridopoulos

“…Conclusions Patients who are cytomegalovirus‐positive with STEMI have impaired reperfusion, reduced left ventricular function, and less improvement in health‐related quality of life over 3 months.…”
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Rehabilitation Impact of Vivifrail Exercise Program Type C on the Cognitive Function of Pre-Frail Elderly People in the Community by Sri Soenarti, Dwi Indriani Lestari, Muhammad Barlian Nugroho, Harien Lestari, Tita Hariyanti

“…However, its impact on cognitive function in pre-frail elderly people had not been well studied. …”
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Novel functional eQTL-SNPs associated with susceptibility to occupational pulmonary fibrosis: A multi-stage study by Rui Zhao, Xiaobo Tao, Wendi Zhang, Siqi Li, Shenxuan Zhou, Anhui Ning, Zhenyu Li, Minjie Chu, Wei Wang, Junhong Jiang

“…Aim: Identifying the common functional single-nucleotide polymorphisms (SNPs) that can both affect the susceptibility to idiopathic pulmonary fibrosis (IPF) and silicosis. …”
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Longitudinal trajectories of cognitive, functional, and neuropsychiatric decline in Alzheimer’s disease during COVID-19 lockdown in South Korea by Hahyun Lee, Soojin Shin, Gieun Nam, Seyul Kwak, Yoon Soo Cho, Eunji Hwang, Sohee Oh, So Yoon Kim, So Young Yoo, Jun-Young Lee

“…Significant trajectories of decline in cognitive function and functional abilities were observed over time, with more pronounced declines in higher AD severity groups. …”
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Transposon-sequencing across multiple Mycobacterium abscessus isolates reveals significant functional genomic diversity among strains by Chidiebere Akusobi, Sanjeevani Choudhery, Bouchra S. Benghomari, Ian D. Wolf, Shreya Singhvi, Thomas R. Ioerger, Eric J. Rubin

“…Given the growing public health threat of Mab infections, understanding the functional genomic differences among Mab clinical isolates can provide more insight into how its genetic diversity influences gene essentiality, clinically relevant phenotypes, and importantly, potential drug targets. …”
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Association between insecticide exposomics and cognitive function in older adults: an observational study based on NHANES 2011–2014 by Mengfan Zhang, Xiaofang Guo, Yuanjun Chen, Xinghua Liu, Xingdong Lin

“…While our findings offer preliminary evidence, more robust studies are necessary to confirm causality and guide preventive measures.…”
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From Halos to Galaxies. VI. Improved Halo Mass Estimation for SDSS Groups and Measurement of the Halo Mass Function by Dingyi Zhao, Yingjie Peng, Yipeng Jing, Xiaohu Yang, Luis C. Ho, Alvio Renzini, Anna R. Gallazzi, Cheqiu Lyu, Roberto Maiolino, Jing Dou, Zeyu Gao, Qiusheng Gu, Filippo Mannucci, Houjun Mo, Bitao Wang, Enci Wang, Kai Wang, Yu-Chen Wang, Bingxiao Xu, Feng Yuan, Xingye Zhu

“…These new halo mass estimates enable more accurate investigation of the galaxy–halo connection and the role of halos in galaxy evolution.…”
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Functional Trait Responses of <i>Brasenia schreberi</i> to Water and Soil Conditions Reveal Its Endangered Status by Jingyu Yao, Zhenya Liu, Junbao Yu, Yun Zhang, Rui Xu, Jiahua Li, Yang Xu, Mei Sun

“…By measuring the key functional traits of <i>B. schreberi</i> and detecting the water and soil parameters at the collecting sites, the responses of these functional traits to the water and soil conditions have been investigated. …”
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Hip disarticulation for non-salvageable primary malignant sarcoma of femur: What were the oncological &amp; functional outcomes? by Vikas Warikoo, Jebin Aron, Abhijeet Ashok Salunke, Nandlal Bharwani, Dhruv Patel, Anish Chowdhury, Arunsrinivas Muralidharan, Ajinkya Pawar, Vivek Bande, Shashank Pandya

“…To employ emerging technology to enhance the quality of life and prosthetic limb, more research and study must be done.…”
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