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3461
Real meat shows good performance in maintaining colonic barrier function at a recommended amount of intake in mice
Published 2025-01-01“…Abstract This study aimed to investigate the effects and underlying mechanisms of real meat and plant‐based meat analogs on intestinal barrier function. Methods including PacBio sequencing, HPLC, histological observation, western blotting, and RT‐qPCR were jointly applied. …”
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3462
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The dynamics of microbial community structure and metabolic function in different parts of cigar tobacco leaves during air-curing
Published 2024-12-01“…Microbial community diversity analysis indicated that species richness and diversity were significantly higher during the fresh leaf and withering periods. Functional prediction based on PICRUSt2 suggested that the microbial communities in the middle leaves exhibited higher abundances of metabolic pathways related to carbohydrates and amino acids than those in the upper leaves, potentially leading to the formation of more flavor compounds. …”
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3464
Wound repair and immune function in the Pseudomonas infected CF lung: before and after highly effective modulator therapy
Published 2025-04-01“…With the approval of highly effective modulator therapies like elexacaftor/tezacaftor/ivacaftor (ETI), pwCF eligible for ETI have seen drastic improvements in lung function and clinical outcomes, including an increased life expectancy. …”
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3465
Complex interplay between gene deletions and the environment uncovers cellular roles for genes of unknown function in Escherichia coli
Published 2025-07-01“…In a subsequent step, we used this cross-condition data set to identify five genes of unknown function (yibN, yaaY, yfaQ, ybiJ, and yijD), of which the deletion displayed either nutrient-independent phenotypic deviations or phenotypic similarities to genes of known function. …”
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3466
Efficacy of elongated needles for motor and balance function after a stroke: a systematic review and meta-analysis
Published 2025-05-01“…Furthermore, elongated needles, whether applied alone or in combination with other therapies, significantly improved the motor function of limbs in patients (SMD = 1.21, P < 0.00001, I2 = 92%, 95% CI = 0.63–1.79). …”
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3467
Novel role of microphthalmia-associated transcription factor in modulating the differentiation and immunosuppressive functions of myeloid-derived suppressor cells
Published 2023-01-01“…Furthermore, IHC staining of human tumor tissues revealed that MITF+ MO-MDSCs are more frequently observed in tumor tissues than in tumor-free draining lymph nodes obtained from patients with cancer.Conclusions Our results indicate that MITF regulates the differentiation and function of MDSCs and can be a novel therapeutic target for modulating MDSC activity in immunosuppressive TMEs.…”
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3468
Preoperative renal functional reserve as a predictor of acute kidney injury in young adults with congenital heart disease
Published 2025-07-01“…Abstract Due to advances in medical and surgical care, there are more adults than children living with congenital heart disease (CHD). …”
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3469
Effects of Long-Term Heavy Metal Exposure on the Species Diversity, Functional Diversity, and Network Structure of Oral Mycobiome
Published 2025-03-01“…Simultaneously, the functional annotation of fungi was performed using FUNGuild, and co-occurrence networks were constructed to analyze the interactions of different functional fungi. …”
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MRI-based analysis of the microstructure of the thalamus and hypothalamus and functional connectivity between cortical networks in episodic cluster headache
Published 2025-01-01“…Results Patients with CH had less FC between the salience network (SN) and left executive control network (ECN) than HCs, but more FC between the default mode network and right ECN. …”
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3474
Situating the salience and parietal memory networks in the context of multiple parallel distributed networks using precision functional mapping
Published 2025-01-01“…Summary: Brain networks serving higher cognitive functions are widely distributed across frontal and posterior association zones. …”
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3475
Effects of hemodilution on coagulation function during prolonged hypotensive resuscitation in a porcine model of severe hemorrhagic shock
Published 2023-12-01“…Background Although hemorrhage remains the leading cause of survivable death in casualties, modern conflicts are becoming more austere limiting available resources to include resuscitation products. …”
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3476
FEATURES OF WRITTEN LANGUAGE COMMUNICATION BY MEANS OF THE UKRAINIAN LANGUAGE (on the example of official-business, epistolary and conversational-functional styles)
Published 2021-06-01“…The article analyzes the main types of oral and written communication on the material of different functional styles of the Ukrainian language. The research methodology consists of both the main methods of functional stylistics and its partial and concrete-practical methods, namely: functional, complex, semantic, comparative methods, multifaceted analysis and the method of direct observation. …”
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3477
IL-1R8 silencing improves the anti-tumor function of freshly isolated human NK cells
Published 2022-03-01“…Furthermore, upon IL-15 activation, the majority of genes involved in NK cell function were upregulated in IL-1R8-siRNA—compared with control—siRNA-transfected NK cells. …”
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Seasonal effects of plant functional groups on molecular biogeochemistry of dissolved organic matter in porewater of a poor fen
Published 2025-04-01“…Studies in which vascular plant functional groups (PFGs) in peatlands have been manipulated to mimic the potential effects of a warming climate on DOM are scarce. …”
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3479
The effects of frailty, mental health, and cardiac function on quality of life in patients undergoing transcatheter aortic valve replacement
Published 2025-07-01“…However, the relationships between frailty, mental health, cardiac function, and QoL in patients after TAVR have not been well-studied. …”
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Effects of childhood trauma on sustained attention in major depressive disorder: the mediating role of brain activity and functional connectivity
Published 2024-12-01“…Abstract Background Sustained attention deficits were reported more significant in patients with major depressive disorder (MDD) than in healthy controls (HCs), and are pivotal in both the development and aggravation of depression. …”
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