Tratamiento quirúrgico de fractura subcapital de cadera no desplazada: Femoral Neck System vs. tornillos canulados. Estudio comparativo by P. Lalueza-Andreu, Á. Martínez-García, P. Checa-Betegón, J. García-Coiradas, J.A. Valle-Cruz, F. Marco-Martínez

“…These results suggest that the FNS could be considered a safer and more effective option compared to cannulated screws.…”
Get full text

O jogo como sistema de avaliação no idoso institucionalizado – um estudo piloto (El juego como sistema de evaluación en ancianos institucionalizados - estudio piloto) (Game perfo... by Marlene Rosa, Raquel Marinho, Sara Gordo, Ricardo Pocinho

“…Conclusion: Our results suggest that the Jogo das Mãos TATI can be used to assess motor coordination and executive functions in institutionalized older adults. Further studies are needed to replicate the results in larger and more heterogeneous samples. …”
Get full text

[Translated article] Surgical treatment of non-displaced subcapital hip fracture: Femoral Neck System vs. cannulated screws. Comparative study by P. Lalueza-Andreu, Á. Martínez-García, P. Checa-Betegón, J. García-Coiradas, J.A. Valle-Cruz, F. Marco-Martínez

“…These results suggest that the FNS could be considered a safer and more effective option compared to cannulated screws. …”
Get full text

Performance of the Surface Water and Ocean Topography (SWOT) Mission for Monitoring Small Lakes in West Africa by Felix Girard, Laurent Kergoat, Ibrahim Mainassara, Maxime Wubda, Edwige Dayangnewende Nikiema, Amadou Abdourhamane Toure, Julien Renou, Maxime Vayre, Nicolas Taburet, Nicolas Picot, Manuela Grippa

“…The volume variability and the hydrological functioning of the thousands of lakes in the Sahelian region are poorly known. …”
Get full text

Genome-Wide Identification and Evolutionary Analysis of m6A-Related Gene Family in Poplar Nanlin895 by Zeyu Li, Rongxia Liu, Mingqiang Zhu, Jinye Zhang, Zhoujin Li, Kaixin Huang, Zehua Ren, Yan Zhao, Keming Luo, Qin Song

“…Purifying selection pressures were observed on all duplicated gene pairs, suggesting their essential roles in functional differentiation. Phylogenetic analysis revealed that writers, erasers, and readers are categorized into six, four, and two groups, respectively, with these genes being more conserved among dicotyledonous plants. …”
Get full text

Multicentre pragmatic embedded stepped wedge cluster randomised trial comparing glucose 5% with sodium chloride 0.9% as the default drug diluent in the ICU: the sweet-water trial p... by Alexander Zarbock, Kai-Uwe Eckardt, Claudia Spies, Felix Balzer, Martin Witzenrath, Philipp Enghard, Björn Tampe, Oliver Hunsicker, Steffen Weber-Carstens, Bjoern Weiss, Jens Nee, Christian Strauss, Heiko Schenk, Jan-Hendrik Bernhard Hardenberg, Ricarda Merle Hinz, Mareen Pigorsch, Alexander Uhrig, Holger Müller-Redetzky, Tim Schroeder, Ulrike Trost, Daniel Zickler, Rainer Borgstedt, Mariam Abu-Tair, Uta Hildebrand, Dario von Wedel

“…Hypernatraemia adversely affects various physiological functions and is associated with delirium, prolonged length of stay and increased ICU and post-discharge mortality. …”
Get full text

Anti‐seasonal flooding drives substantial alterations in riparian plant diversity and niche characteristics in a unique hydro‐fluctuation zone by Ye Liu, Xiaodie Duan, Xiaoling Li, Wenxiong Yi, Gong Chen, Jin Yang, Danli Deng, Xiaojuan Guo, Zhengjian Yang, Guiyun Huang, Meixiang Hu, Chen Ye

“…The results showed anti‐seasonal flooding precipitated the gradual disappearance of the original diverse niches, resulting in the reduction of plant species richness and functional diversity and more obvious competition among plant species with similar resource requirements. …”
Get full text

MicroRNA-665 and its potential role in drug response and survival outcomes in multiple myeloma: a preliminary study by Rui Bergantim, Rui Bergantim, Rui Bergantim, Rui Bergantim, Sara Peixoto da Silva, Sara Peixoto da Silva, Sara Peixoto da Silva, Vanessa Pinto, Vanessa Pinto, Joana M. Pereira, Joana M. Pereira, Diana Sousa, Diana Sousa, Diana Sousa, Fernanda Trigo, Rune Matthiesen, José E. Guimarães, José E. Guimarães, José E. Guimarães, José E. Guimarães, José E. Guimarães, M. Helena Vasconcelos, M. Helena Vasconcelos, M. Helena Vasconcelos

“…In silico analysis for target-prediction and gene ontology (GO) enrichment was performed to explore the potential biological and functional role of the identified miRNAs.ResultsNGS profiling revealed several miRNAs differently expressed between treatment-refractory and sensitive patients, as well as between PB and BM. …”
Get full text

Right-restricting measures implemented by Public Health Surveillance services during the COVID-19 pandemic: a systematic review protocol by Tiago Correia, Marcelo Dayrell Vivas, Larissa Bragagnolo, Igor Antônio Lourenço da Silva, Fernando Tureck, Reinaldo Santos, Samara Kielmann, Debora do Carmo, Camila Avarca, Franciele da Silva, Mariana Paes, Luis Fernando Nogueira Tofani, Arthur Chioro

“…The results will be presented in one or more articles to be submitted to scientific journals and may also be presented at scientific conferences and to public policy makers.PROSPERO registration number This systematic review protocol was registered with the International Prospective Register of Systematic Reviews (PROSPERO) on 20 November 2024 (registration number CRD42024613039).…”
Get full text

An optimized integrin α6-targeted peptide capable of delivering toxins for melanoma treatment by Zheng Zhao, Zi-Qian Li, Ying-Bin Huang, Meng-meng Liu, Fei Cao, Guo-Long Bu, Peng-Fei Xu, Qi Fang, Zhu-Long Hu, Di Wu, Guo-Kai Feng, Xue-Kui Liu

“…Methods We developed a new combination strategy for the synthesis of penetrating peptides functionalized with targeting of integrin α6. The linear peptide S5 was multimerized with 4 copies in linear sequential order spaced by GSG between each copy to yield the 4S5 peptide. …”
Get full text

Abstract 049: Effect of the ICA Lesion Severity in Outcomes after Endovascular Treatment of Acute Tandem LVO by Milagros Galecio Castillo, Mudassir Farooqui, Ameer Hassan, Mouhammad Jumaa, Afshin Divani, Marc Ribo, Michael Abraham, Nils Petersen, Johanna Fifi, Waldo Guerrero, Amer Malik, James Siegler, Thanh Nguyen, Sunil Sheth, Albert Yoo, Guillermo Linares, Nazli Janjua, Darko Quispe‐Orozco, Wondwossen Tekle, Syed Zaidi, Asad Ikram, Marta Olivé‐Gadea, Abid Qureshi, Alex Devarajan, Linda Zhang, Mohamad Abdalkader, Cynthia Zevallos, Sergio Salazar Marioni, Jazba Sooomro, Weston Gordon, Charoskhon Turabova, Juan Vivanco‐Suarez, Aaron Rodriguez‐Calienes, Maxim Mokin, Dileep Yavagal, Santiago Ortiz‐Gutierrez

“…Clinical outcomes, including functional independence, hemorrhagic events, and procedural time metrics including puncture to reperfusion time were assessed. …”
Get full text

Unveiling conserved HIV-1 open reading frames encoding T cell antigens using ribosome profiling by Lisa Bertrand, Annika Nelde, Bertha Cecilia Ramirez, Isabelle Hatin, Hugo Arbes, Pauline François, Stéphane Demais, Emmanuel Labaronne, Didier Decimo, Laura Guiguettaz, Sylvie Grégoire, Anne Bet, Guillaume Beauclair, Antoine Gross, Maja C. Ziegler, Mathias Pereira, Raphaël Jeger-Madiot, Yann Verdier, Joelle Vinh, Sylvain Cardinaud, Stéphanie Graff-Dubois, Audrey Esclatine, Cécile Gouttefangeas, Marcus Altfeld, Laurent Hocqueloux, Assia Samri, Brigitte Autran, Olivier Lambotte, Hans-Georg Rammensee, Emiliano P. Ricci, Juliane Walz, Olivier Namy, Arnaud Moris

“…In the blood of people living with HIV, ARF-derived peptides elicit potent poly-functional T cell responses mediated by both CD4+ and CD8+ T cells. …”
Get full text

The Structural Model of Happiness Based on Mindfulness with Mediator Role of Emotional Intelligence, Self-Compassion and Resilience by Mohammad Reza Tamannai far, Faezeh Taraffo

“…In fact, mindfulness is associated with higher positive affect, lower negative affect, and higher life satisfaction (Brown & Ryan, 2003).In explaining the results of the conceptual model test of the current research, it can be said that some preliminary evidence suggests that higher levels of mindfulness are associated with more adaptive emotional functioning, operationalized as emotional intelligence. …”
Get full text

Novel trispecific killer engager targeting B7-H3 enhances natural killer cell antitumor activity against head and neck cancer by Jeffrey S Miller, Martin Felices, Peter Hinderlie, James Lim, Naomi Fujioka, Shee Kwan Phung, Yvette Soignier, Joshua T Walker, Melissa A Geller, Madison Shackelford, Carly Selleck, Philippa R Kennedy, Mihir Shetty, Melissa J Khaw, Paolo P Provenzano, Nicholas A Zorko, Laura E Bendzick, Riley C Lyons, Elise L Femino, Terran Stenger, Tumpa Dasgupta, Laura E Kotz, Eng Hock Lee, Quynhanh Lu, Zachary B Davis, John E Wagner, Margaret L MacMillan

“…Furthermore, patients with Fanconi anemia (FA) have a genetic predisposition with a 500-fold to 700-fold higher incidence of HNSCC. Thus, novel and more efficacious therapies are needed. As current immunotherapies often fail due to suppressive elements in the tumor microenvironment (TME), we developed a trispecific killer engager (TriKE) to direct multiple signals to natural killer (NK) cells to overcome the hypoxic TME. …”
Get full text

A highly conserved sRNA downregulates multiple genes, including a σ54 transcriptional activator, in the virulence mode of Bordetella pertussis by Minji Sim, Jeffers Nguyen, Karolína Škopová, Kyungyoon Yoo, Chin-Hsien Tai, Leslie Knipling, Qing Chen, David Kim, Summer Nolan, Rawan Elaksher, Nadim Majdalani, Hernan Lorenzi, Scott Stibitz, Kyung Moon, Deborah M. Hinton

“…We show that transcription from a σA-dependent promoter yields a long form of 190 nucleotides (nt) that is processed by RNase E to generate a shorter, more stable form (BpsA-S) of 67 nt. The transcript also encodes a small protein of 32 amino acids. …”
Get full text

Genome-Wide Association Study of Brown Rice Weight Identifies an RNA-Binding Protein Antagonistically Regulating Grain Weight and Panicle Number by Lin Zhou, Hong Jiang, Long Huang, Ziang Li, Zhonghao Yao, Linhan Li, Kangwei Ji, Yijie Li, Haijuan Tang, Jinping Cheng, Yongmei Bao, Ji Huang, Hongsheng Zhang, Sunlu Chen

“…Notably, compared with GW, brown rice weight (BRW) provides a more direct metric associated with actual grain yield potential. …”
Get full text

Effects of increasing levels of dietary cation–anion difference on growth performance, nutrient digestibility, rumen fermentation, and rumen microbiota in fattening Hu sheep by Yu Wang, Wenjin Zheng, Hongwei Duan, Jiazhi Luo, Yuyang Yin, Junshi Shen, Shengyong Mao, Weiyun Zhu, Zhongtang Yu

“…The dietary cation–anion difference (DCAD) has the potential to influence the physiological functions of animals. Nonetheless, there is a notable scarcity of research in the field of ruminant science regarding its effects on fattening sheep, particularly with respect to the rumen microbiota. …”
Get full text

Identifying Heat Adaptability QTLs and Candidate Genes for Grain Appearance Quality at the Flowering Stage in Rice by Lei Chen, Weiwei Chen, Jin Li, Yu Wei, Dongjin Qing, Juan Huang, Xinghai Yang, Maoyan Tang, Zhanying Zhang, Jianping Yu, Guofu Deng, Gaoxing Dai, Chao Chen, Tianfeng Liang, Yinghua Pan

“…Haplotype analysis indicated that Hap1 is the superior haplotype, and pyramiding more than two superior alleles improved rice grain appearance quality (longer GL, wider GW, and lower GC) in high-temperature environments. …”
Get full text

Study of the effect of human placenta hydrolysate in a new model of metabolic-associated fatty liver disease with iron overload by T. E. Bogacheva, O. A. Gromova, I. Yu. Torshin, V. I. Demidov, A. G. Kalacheva, A. A. Garanin, I. V. Gogoleva, L. E. Fedotova, O. A. Limanova, А. N. Mnatsakanyan, N. Yu. Zhidomorov, T. R. Grishina

“…The model was used to test the effectiveness of using standardized HPH and to characterize complex changes in more than 20 biomarkers of liver and kidney functions, hematopoiesis, inflammation, and thrombus formation.Results. …”
Get full text

Home Respiratory Therapies in Patients With Obstructive Sleep Apnea: A Value-based Care Model in Spain by Irene Cano-Pumarega, Candela Caballero-Eraso, Valentín Cabriada, Mar Mosteiro, Juan Fernando Masa, Ferran Barbé

Get full text