PI3Kδ activation, IL-6 overexpression, and CD37 loss cause resistance to naratuximab emtansine in lymphomas by Alberto J. Arribas, Sara Napoli, Eugenio Gaudio, Charles Herbaux, Eleonora Cannas, Chiara Tarantelli, Roberta Bordone-Pittau, Luciano Cascione, Nicolas Munz, Luca Aresu, Jacopo Sgrignani, Andrea Rinaldi, Ivo Kwee, Davide Rossi, Andrea Cavalli, Emanuele Zucca, Georg Stussi, Anastasios Stathis, Callum Sloss, Matthew S. Davids, Francesco Bertoni

“…The activity, primarily cytotoxic, was more potent in B- than T-cell lymphoma cell lines. …”
Get full text

Thrombectomy in patients with basilar artery thrombosis by G. R. Ramazanov, E. A. Kovaleva, E. V. Klychnikova, L. S. Kokov, H. V. Korigova, R. Sh. Muslimov, M. V. Parkhomenko, S. S. Petrikov, V. N. Stepanov

“…In randomized trials, it was found that RT, whether it is sTLT, TE or a combination of these techniques, despite the best degree of functional recovery in patients by day 90 from the onset of the disease, does not lead to a statistically significant decrease in mortality. …”
Get full text

Effectiveness of Group Problem Management Plus, a brief psychological intervention for adults affected by humanitarian disasters in Nepal: A cluster randomized controlled trial. by Mark J D Jordans, Brandon A Kohrt, Manaswi Sangraula, Elizabeth L Turner, Xueqi Wang, Pragya Shrestha, Renasha Ghimire, Edith Van't Hof, Richard A Bryant, Katie S Dawson, Kedar Marahatta, Nagendra P Luitel, Mark van Ommeren

“…Group PM+ was not associated with lower PTSD symptoms or functional impairment. Use of psychosocial skills at midline was estimated to explain 31% of the PM+ effect on endline GHQ-12 scores. …”
Get full text

A Sociological Study of Monetary Attitudes among Citizens of Tehran by Nahid Abdoli, Asadollah Babaiefard

“…Currently, the cultural and social functions of money—understood as a "fait social total"—are undergoing significant changes. …”
Get full text

Environmental Filtering Effect Drives the Plant Species Distribution in Alpine Grasslands on the Qinghai‐Tibetan Plateau by Yikang Cheng, Ding Li, Nadia I. Maaroufi, Jianling You, Wen Zhou, Wensheng Liu, Danhui Qi, Xiang Liu, Yuguo Wang, Xiaoyun Pan, Wenju Zhang, Ji Yang, Shurong Zhou, Zhiping Song

“…In this study, a total of 27 study sites were established along a north–south transect and a west–east transect across the eastern QTP; the two furthest sites were more than 1000 km apart. We analyzed the taxonomic, functional, and phylogenetic diversity and structure of these communities to elucidate the relative importance of dispersal limitation and environmental filtering effects that shape plant distributions at the regional (i.e., encompassing all sites) and the transect scales. …”
Get full text

Hard rock aquifer architecture and water circulation levels in the Strengbach critical zone observatory (France) by Chabaux, François, Négrel, Philippe, Gal, Frederick, Viville, Daniel, Ranchoux, Coralie, Van der Woerd, Jérome, Delay, Frederick, Ackerer, Julien, Aquilina, Luc, Diraison, Marc, Masson, Frédéric, Mériaux, Anne-Sophie, Labasque, Thierry, Lucas, Yann, Pezard, Philippe Adrien, Reuschlé, Thierry, Schmitt, Anne-Désirée, Stille, Peter, Wyns, Robert, Lerouge, Catherine, Dezayes, Chrystel

“…In contrast, the south-facing and more easterly slope shows a mobile saprolite horizon with limited vertical extension (${\approx }$2–3 m thick). …”
Get full text

Thinning intensity influences the C:N:P stoichiometry in forest ecosystems: A global synthesis by Chongwei Fan, Guiyao Zhou, Hongyang Chen, Zhenggang Du, Ruiqiang Liu, Yanghui He, Changjiang Huang, Shuying Qiu, Yimin Zhu, Jie Li, Xuhui Zhou

“…Future forest management could implement an appropriate forest thinning intensity to ensure ecosystem functionality and maintain the balance and stability of ecosystem elements.…”
Get full text

Comprehensive analysis of exosome-related gene signature in multiple myeloma prognosis and immune microenvironment evaluation by Dong Zheng, Bingxin Zhang, Quanqiang Wang, Sisi Zheng, Yibo Xia, Ziwei Zheng, Zhili Lin, Shuxia Zhu, Xinyi Zhang, Luning Cui, Hansen Ying, Tianyu Zhang, Shujuan Zhou, Zixing Chen, Enqing Lan, Yu Zhang, Xuanru Lin, Jingjing Chen, Honglan Qian, Xudong Hu, Yan Zhuang, Zuoting Xie, Xiangjing Zhou, Zhouxiang Jin, Songfu Jiang, Yongyong Ma

“…Therefore, we aim to establish a more accurate model to evaluate the prognosis of MM patients based on the exosome-related genes. …”
Get full text

Carbon dioxide flush as a soil health indicator in contrasting edaphoclimatic conditions by Lucila Bassi, Cecilia Crespo, Gisela Vanesa García, Walter Daniel Carciochi, Nahuel Ignacio Reussi Calvo, Pablo Barbieri, Hernán René Sainz Rozas, Nicolás Wyngaard

“…The FCO2 effectively differentiated soybean monoculture from more diverse cropping systems, particularly in the 0–5  cm soil layer. …”
Get full text

Clinical and cost-effectiveness of first contact physiotherapy for musculoskeletal disorders in primary care: the FRONTIER, mixed method realist evaluation by Nicola E Walsh, Alice Berry, Serena Halls, Rachel Thomas, Hannah Stott, Cathy Liddiard, Zoe Anchors, Fiona Cramp, Margaret E Cupples, Peter Williams, Heather Gage, Dan Jackson, Paula Kersten, Dave Foster, Justin Jagosh

“…There was no evidence to determine whether the model was more clinically efficacious or cost-effective than GP-led models of care. …”
Get full text

Histone deacetylases facilitate Th17-cell differentiation and pathogenicity in autoimmune uveitis via CDK6/ID2 axis by Chun Zhang, Xiuxing Liu, Chenyang Gu, Yuhan Su, Jianjie Lv, Yidan Liu, Yuehan Gao, Hui Chen, Nanwei Xu, Jing Xiao, Zhuping Xu, Wenru Su

“…However, underlying pathogenesis of AU required to develop more efficient therapy remain unclear. Methods: We isolated peripheral blood mononuclear cells (PBMCs) from AU patients and performed single-cell RNA sequencing (scRNA-seq). …”
Get full text

Safety and Efficacy in the Transcortical and Transsylvian Approach in Insular High-Grade Gliomas: A Comparative Series of 58 Patients by Alberto Morello, Francesca Rizzo, Andrea Gatto, Flavio Panico, Andrea Bianconi, Giulia Chiari, Daniele Armocida, Stefania Greco Crasto, Antonio Melcarne, Francesco Zenga, Roberta Rudà, Giovanni Morana, Diego Garbossa, Fabio Cofano

“…There are two main surgical approaches to address the complex vascular network and functional areas around the insula: the transsylvian approach and the transcortical approach. …”
Get full text

Intrinsic capacity in patients with dementia with Lewy bodies compared with those with Alzheimer’s disease: A cross-sectional study by Marie Collin, Justine Bonnet-Chateau, Victor Gilles, Sophie Dautricourt, Thomas Gilbert, Zaza Makaroff, Marie-Hélène Coste, Virginie Dauphinot, Antoine Garnier-Crussard

“…As IC decline is associated with the risk of frailty, functional decline and disability and is potentially reversible after targeted interventions, a monitoring and specific management of IC decline in patients with DLB could promote healthy aging in this population. …”
Get full text

Some epidemiological indicators and results of surgical treatment of children with unstable and complicated spine injuries using different models of medical care based on the examp... by I.V. Basankin, S.V. Vissarionov, A.A. Gyulzatyan, A.A. Afaunov, K.K. Takhmazyan, V.K. Shapovalov, L.A. Tarasenko, A.M. Efremov, A.V. Sobolev, A.A. Danileichenko

“…In total, the number of children and adolescents hospitalized for surgical treatment in the periods under review increased more than 4-fold (by 332.0 %), and the number of complicated spinal injuries increased less than 2-fold (86.7 %). …”
Get full text

Association between care complexity individual factors and older inpatients with COVID-19: a cross-sectional study by Jordi Adamuz, Jordi Adamuz, Jordi Adamuz, Julia González-Vaca, Julia González-Vaca, Maribel González-Samartino, Maribel González-Samartino, Maribel González-Samartino, María-Magdalena López-Jiménez, María-Magdalena López-Jiménez, María-Magdalena López-Jiménez, Andrea Urbina, Andrea Urbina, Andrea Urbina, Oliver Polushkina-Merchanskaya, Sergio Alonso-Fernández, Sergio Alonso-Fernández, Silvia Esteban-Sepúlveda, Silvia Esteban-Sepúlveda, Sergio Barrientos-Trigo, Maria-Eulàlia Juvé-Udina, Maria-Eulàlia Juvé-Udina

“…The analysis shows that middle-old (75–84 years) patients were associated with chronic disease, position impairment, urinary or fecal incontinence, anatomical and functional disorders, vascular fragility, involuntary movements, fear or anxiety and mental status impairments. …”
Get full text

Handling of missing component information for common composite score outcomes used in axial spondyloarthritis research when complete-case analysis is unbiased by Christos Polysopoulos, Stylianos Georgiadis, Lykke Midtbøll Ørnbjerg, Almut Scherer, Daniela Di Giuseppe, Merete Lund Hetland, Michael John Nissen, Gareth T. Jones, Bente Glintborg, Anne Gitte Loft, Johan Karlsson Wallman, Karel Pavelka, Jakub Závada, Ayten Yazici, Maria José Santos, Adrian Ciurea, Burkhard Möller, Brigitte Michelsen, Pawel Mielnik, Johanna Huhtakangas, Heikki Relas, Katja Perdan Pirkmajer, Ziga Rotar, Ross MacDonald, Bjorn Gudbjornsson, Irene van der Horst-Bruinsma, Marleen van de Sande, Myriam Riek

“…When a complete-case (CC) analysis of composite scores is unbiased, preferable approaches of dealing with missing component information should also be unbiased and provide a more precise estimate. We assessed the performance of several methods compared to CC analysis in estimating the means of common composite scores used in axial spondyloarthritis research. …”
Get full text

Vitamin D receptor genetic variations in association to the susceptibility to prostate cancer: a case-control study in a Moroccan population by Kawtar Nabil, Abdelilah Laraqui, Ikram Tiabi, Kaoutar Anouar Tadlaoui, Mohammed Mrabti, Ahmed Ameur, Khalid Ennibi, Mustapha Benhessou, Moulay Mustapha Ennaji

“…Aim: It has been shown that the vitamin D receptor (VDR) gene and its biological functions can be affected by genetic alterations in the VDR gene. …”
Get full text

Influences of electrode density on intracranial seizure localisation: a single-blinded randomised crossover studyResearch in context by Ebenezer O. Chinedu-Eneh, Sharon Chiang, John P. Andrews, Ehsan Tadayon, Joline M. Fan, Paul A. Garcia, Ernesto Gonzalez-Giraldo, Manu Hegde, Patrick Hullett, Vikram R. Rao, Robert C. Knowlton, Edward F. Chang, Jonathan K. Kleen

“…While further studies assessing surgical outcomes in more patients are needed, these results suggest higher densities of electrodes on already-implanted hardware may reveal sub-centimetre extensions and clearer functional contiguity of the SOZ(s) for better appraisals of pathophysiological margins in epilepsy surgery. …”
Get full text

全球教師社群研究之趨勢分析 Analysis of Trends in Global Teacher Community Research by 謝傳崇 Chuan-Chung Hsieh, 宋雨柔 Yurou Song, 沈芷嫣 Jr-Yan Shen, 江宛霖 Wan-Lin Chiang, 古耘睿 Yun-Ruei Ku

“…The findings aim to provide a more comprehensive theoretical framework and practical insights for future studies and educational practices. …”
Get full text

中學生成長型思維與學習投入之關係： 以後設認知與羞愧感為中介變項 A Study on the Impact of Growth Mindset on Learning Engagement Among Junior and Senior High School Students: Exploring the Mediating Roles of Metac... by 王佳琪 Chia-Chi Wang, 孫國瑋 Guo-Wei Sun

“…Students with high levels of metacognition focus more on the learning process, perceiving it as part of strategic execution and outcome evaluation, which increases their willingness to engage in learning (Brock & Hundley, 2017). …”
Get full text