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  1. 33561
  2. 33562
  3. 33563

    Impaired mucosal IgA response in patients with severe COVID-19 by Melyssa Yaugel-Novoa, Blandine Noailly, Fabienne Jospin, Andrés Pizzorno, Aurélien Traversier, Bruno Pozzetto, Louis Waeckel, Stéphanie Longet, Sylvie Pillet, Elisabeth Botelho-Nevers, Manuel Rosa-Calatrava, Thomas Bourlet, Stéphane Paul

    Published 2024-12-01
    “…We found that the early systemic IgA response strongly induced in patients with severe disease did not block IgG neutralization functions and activated FcRs more effectively than IgG. …”
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  4. 33564
  5. 33565
  6. 33566
  7. 33567

    Unveiling the Therapeutic Potential: Targeting Fibroblast-like Synoviocytes in Rheumatoid Arthritis by Siran Yue, Junyu Fan, Duoli Xie, Chunhao Cao, Zhuqian Wang, Jie Huang, Fang Qiu, Xu Yang, Dongyi He, Aiping Lu, Chao Liang

    Published 2025-01-01
    “…A deeper understanding of the molecular and functional heterogeneity of FLS may pave the way for more effective and precise therapeutic interventions in RA.…”
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  8. 33568
  9. 33569
  10. 33570

    Systematic metabolic engineering enables highly efficient production of vitamin A in Saccharomyces cerevisiae by Yi Shi, Shuhuan Lu, Xiao Zhou, Xinhui Wang, Chenglong Zhang, Nan Wu, Tianyu Dong, Shilong Xing, Ying Wang, Wenhai Xiao, Mingdong Yao

    Published 2025-03-01
    “…Vitamin A is a micronutrient critical for versatile biological functions and has been widely used in the food, cosmetics, pharmaceutical, and nutraceutical industries. …”
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  11. 33571

    Climate science for 2050 by Guy Brasseur, Guy Brasseur, Detlef Stammer, Pierre Friedlingstein, Pierre Friedlingstein, Gabriele Hegerl, Tiffany Shaw, Kevin Trenberth, Kevin Trenberth, Jadwiga Richter, Carolina Vera, André Berger, Helen Cleugh, Steve Easterbrook, Paul Edwards, Daniela Jacob, Michael Mann, Valérie Masson-Delmotte, Gavin Schmidt, Mary Scholes, Thomas Stocker, Martin Visbeck, Guoxiong Wu

    Published 2025-05-01
    “…Knowledge of the functioning of the climate system, including the physical, dynamical and biogeochemical feedback processes expected to occur in response to anthropogenic climate forcing, has increased substantially over recent decades. …”
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  12. 33572

    Seasonal Influenza Vaccination Programs in the Americas: A Platform for Sustainable Life-Course Immunization and Its Role for Pandemic Preparedness and Response by Francisco Nogareda, Margherita Ghiselli, Martha Velandia-González, Bremen de Mucio, Jorge Jara, Paula Couto, Angel Rodriguez, Marc Rondy, Andrea Vicari, Murat Hakan Ozturk, Shoshanna Goldin, Alba Vilajeliu, Eva Leidman, Jaymin Patel, Julie Carlton, Ashley L. Fowlkes, Eduardo Azziz-Baumgartner, Daniel Salas Peraza, Alba Maria Ropero

    Published 2024-12-01
    “…Overall, countries with existing seasonal influenza vaccination programs were better prepared and rolled out the delivery of COVID-19 vaccines more quickly and effectively compared to other countries where the influenza vaccination platform was weak or non-existent. …”
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  13. 33573
  14. 33574

    Comparative transcriptome profiling and co-expression network analysis reveals important genes regulating maize response to Southern corn rust by Jialong Liu, Kailai Wang, Nan Wang, Yuan Zhong, Xiuzhen Zhai, Yinsuo Jia, Zhiying Chu, Qing Miao, Hao Su, Mengyun Kou, Huijun Duan, Xiaocui Yan

    Published 2025-07-01
    “…This study used six maize inbred lines (DTMA-45, DTMA-50, R99, N110, P767 and 15B020F3) as materials to systematically explore the response mechanism of maize to southern corn rust through phenotype identification, transcriptome sequencing, functional enrichment analysis, gene co-expression network analysis, and quantitative RT-PCR experiments. …”
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  15. 33575

    ROS-responsive drug delivery system with enhanced anti-angiogenic and anti-inflammatory properties for neovascular age-related macular degeneration therapy by Jiayi Zuo, Yining Pan, Yuanli Wang, Wei Wang, Haojie Zhang, Si Zhang, Youru Wu, Jiangfan Chen, Qingqing Yao

    Published 2025-06-01
    “…Therefore, combinational therapeutics with anti-angiogenic, reactive oxygen species (ROS)-scavenging and anti-inflammatory functions will broaden therapeutic effects and reduce side effects. …”
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  16. 33576

    Genetic association of the kynurenine pathway to suicidal behavior by Rabah Tamimou, Christine Montout, Thibault Mura, Ismael Conejero, Alexandre Evrard, Philippe Courtet, Pablo Bonilla-Escribano, Carlos Riaza, Concepción Vaquero-Lorenzo, Enrique Baca-Garcia, Fabrice Jollant, Serge Lumbroso, Kevin Mouzat, Jorge Lopez-Castroman

    Published 2024-12-01
    “…To explore this possibility, we hypothesized that these genetic variations would occur more frequently in patients with a history of suicidal behavior compared to non-suicidal individuals. …”
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  17. 33577
  18. 33578

    Transcriptome-wide dynamics of m6A methylation in ISKNV and Siniperca chuatsi cells infected with ISKNV by Qijin Miao, Jing Jiang, Siyou Huang, Jie Gao, Qingqing Liu, Rui Zheng, Yiling Kang, Changjun Guo, Jianguo He, Junfeng Xie

    Published 2025-01-01
    “…The findings revealed that the m6A methylation peaks were located mainly in coding sequences (CDSs), with more than 90% of the transcripts containing 1–5 m6A peaks. …”
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  19. 33579

    Deciphering the mechanisms for preferential tolerance of Escherichia coli BL21 to Cd(II) over Cu(II) and Ni(II): A combined physiological, biochemical, and multiomics perspective by Jackson Nkoh Nkoh, Ting Ye, Chenjing Shang, Chunyuan Li, Jianguang Tu, Sihui Li, Zuping Wu, Pengyu Chen, Quaid Hussain, Seraphine Nkie Esemu

    Published 2025-06-01
    “…Environmental pollution severely affects ecological functions/health, and nondegradable pollutants such as heavy metals (HMs) cause significant damage to living organisms. …”
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  20. 33580

    Understanding the Broad-line Region of Active Galactic Nuclei with Photoionization. I. The Moderate-accretion Regime by Qiaoya Wu, Yue Shen, Hengxiao Guo, Scott F. Anderson, W. N. Brandt, Catherine J. Grier, Patrick B. Hall, Luis C. Ho, Yasaman Homayouni, Keith Horne, Jennifer I-Hsiu Li, Donald P. Schneider

    Published 2025-01-01
    “…Here we perform a detailed photoionization investigation of expected broad-line properties as functions of accretion parameters using AGN continuum models from qsosed . …”
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