PPIH Expression Correlates with Tumor Aggressiveness and Immune Dysregulation in Hepatocellular Carcinoma by Bei J, Sun Z, Fu R, Huang X, Huang J, Luo Y, Li Y, Chen Y, Wei Z

“…Immune infiltration was analyzed via CIBERSORT and ssGSEA, while DNA methylation and somatic mutation analyses were performed using MExpress and “maftools”, respectively, alongside in vitro and in vivo experiments to assess PPIH’s functional roles.Results: Our findings indicated that PPIH is significantly upregulated in various cancer types, correlating with poor patient prognosis, increased somatic mutations, and altered gene methylation patterns. …”
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Clinicо-morphological diagnostics and surgical treatment of paraduodenal pancreatitis by V. H. Yareshko, V. O. Tumanskyi, Yu. O. Mikheiev, O. M. Kiosov, A. O. Steshenko, N. O. Yareshko, A. V. Kanaki

“…In the long-term period, there was an improvement in the condition of 2 patients with stabilization of weight and an improvement in the functional state according to the scales of the SF-36 and EORTIC questionnaires. …”
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Penerapan Metode K-Means Clustering dan Simple Moving Average untuk Memprediksi Jenis Penyakit di Provinsi Jawa Timur by Shynta Ayu Dwi Darmawan, Karmilasari

“…The results of this study have practical implications for improving the effectiveness of disease management in East Java Province by more accurately identifying regional priorities and making better decisions based on data. …”
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PULMONARY-RENAL SYNDROME: DIFFICULTIES OF DIFFERENTIAL DIAGNOSIS by D. Yu. Andriyashkina, N. A. Demidova, N. A. Shostak, N. A. Tutaev, A. D. Ershov, D. K. Dudin

“…Chronic heart failure 2А, functional class IV. Mixed anemia (iron-deficient, chronic disease), severe. …”
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ROLE OF CYTOXIC T-LYMPHOCYTES IN THE PATHOGENESIS OF PRETERM BIRTH by N. R. Radzhabova, N. Yu. Sotnikova, A. V. Kudryashova, N. Yu. Borzova, A. I. Malyshkina

“…The increase in CD8+Tn levels is more pronounced in the subgroup of women with a favorable pregnancy outcome. …”
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RETRACTED ARTICLE: Dclk1, a tumor stem cell marker, regulates pro-survival signaling and self-renewal of intestinal tumor cells by Parthasarathy Chandrakesan, Jiannan Yao, Dongfeng Qu, Randal May, Nathaniel Weygant, Yang Ge, Naushad Ali, Sripathi M. Sureban, Modhi Gude, Kenneth Vega, Eddie Bannerman-Menson, Lijun Xia, Michael Bronze, Guangyu An, Courtney W. Houchen

“…Abstract Background More than 80% of intestinal neoplasia is associated with the adenomatous polyposis coli (APC) mutation. …”
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Sistem Monitoring Trafo Distribusi PT.PLN (Persero) berbasis IoT by Budi Eko Prasetyo, Widhy Hayuhardhika Nugraha Putra, Dahnial Syauqy, Adhitya Bhawiyuga, Sigi Syah Wibowo, Ferdian Ronilaya, Indrazno Siradjuddin, Supriatna Adhisuwignjo

“…The DTMS is built to provide early warning functionality to the transformer parameter anomalies such as overload, overvoltage and blackout events. …”
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Individualized frequency and montage tACS to engage theta-gamma coupling and enhance working memory in mild cognitive impairment by Mina Mirjalili, Mina Mirjalili, Iryna S. Palamarchuk, Iryna S. Palamarchuk, Heather Brooks, Heather Brooks, Reza Zomorrodi, Reza Zomorrodi, Ashley Melichercik, Wei Wang, Wei Wang, Sean M. Nestor, Sean M. Nestor, Daniel M. Blumberger, Daniel M. Blumberger, Daniel M. Blumberger, Abhishek Datta, Christopher Bowie, Christopher Bowie, Bernadette Mdawar, Bernadette Mdawar, Kullervo Hynynen, Kullervo Hynynen, Sanjeev Kumar, Sanjeev Kumar, Sanjeev Kumar, Sanjeev Kumar, Tarek K. Rajji, Tarek K. Rajji, Tarek K. Rajji, Tarek K. Rajji

“…Enhancing executive functions in patients with MCI could optimize cognitive compensatory mechanisms and slow cognitive decline. …”
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UFMylation safeguards human hepatocyte differentiation and liver homeostasis by regulating ribosome dissociation by Shuchun Yang, Li Wang, Ran Gao, Yanchang Li, Duo Zhang, Chenxi Wang, Guang Liu, Jie Na, Ping Xu, Xiaoyue Wang, Yuyan Jia, Yue Huang

“…Additionally, we discover that mice with the Rpl26 c.395A>G (p.K132R) mutation are more susceptible to steatosis induced by a high-fat diet. …”
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Near-infrared light-induced photothermal and immunotherapy system for lung cancer bone metastasis treatment with simultaneous bone repair by Guoqing Zhong, Yali Miao, Jielong Zhou, Yijie He, Wenjie Yang, Chongquan Huang, Yunhui Zhang, Jin Xiao, Bingqing Bai, Jiaqi Zhou, Renshan Li, Tiantian Wei, Yu Zhang, Shi Cheng

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Disruption of glutamine transport uncouples the NUPR1 stress-adaptation program and induces prostate cancer radiosensitivity by Uğur Kahya, Vasyl Lukiyanchuk, Ielizaveta Gorodetska, Matthias M. Weigel, Ayşe Sedef Köseer, Berke Alkan, Dragana Savic, Annett Linge, Steffen Löck, Mirko Peitzsch, Ira-Ida Skvortsova, Mechthild Krause, Anna Dubrovska

“…The key parameters of mitochondrial functions were measured by Seahorse analysis. Analysis of the general oxidative stress level and mitochondrial superoxide detection were conducted using flow cytometry. γH2A.X foci analysis was used to assess the DNA double strand break. …”
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Sulfur-rich deposits associated with the deep submarine volcano Fani Maoré support broad microbial sulfur cycling communities by Stéven Yvenou, Mélanie Le Moigne, Olivier Rouxel, Johanne Aubé, Blandine Trouche, Cécile Cathalot, Emmanuel Rinnert, Xavier Philippon, Sandrine Chéron, Audrey Boissier, Vivien Guyader, Yoan Germain, Anne Godfroy, Erwan G. Roussel, Karine Alain

“…Genome-resolved metagenomics, culture-based functional approaches, geochemical and mineralogical analyses were combined to characterize the geological and physico-chemical constraints of the environment surrounding the yellow deposit part of this hotspot volcano and the composition and functions of its microbial community. …”
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Characterization of FosA13, a novel fosfomycin glutathione transferase identified in a Morganella morganii isolate from poultry by Runzhi Zhang, Runzhi Zhang, Yan Yu, Yan Yu, Lulu Huang, Susu Chen, Ruxi Hu, Xiuxiu Wang, Dawei Huang, Chunhan Song, Junwan Lu, Qiyu Bao, Qiyu Bao, Qiyu Bao, Qiyu Bao, Yunliang Hu, Pengfei Jiang, Wei Pan

“…This protein shares the highest aa identity of 55.6% with the functionally characterized protein FosA and has all the essential functional residues of FosA proteins. …”
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Strategy for Construction and Improvement of 4R Resilience Evaluation Model for Coastal Cities by Qixiang QIN, Weiping ZHANG, Yasen YIN

“…The reasons leading to the aforesaid results are mainly summarized in the following three aspects. 1) Due to dense population and land shortage, city samples with high development intensity pay more attention to spatial redundancy and resource acquisition during disasters, and their urban core functional areas have achieved full coverage of public services and emergency service facilities to a large extent through encrypted road networks, mixed land use, vertical functional layout and other ways. …”
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The Efficiency of Complex Differential Treatment of the Patients with Systemic Lupus Erythematous Considering the Features of Bone Tissue Structure Remodeling by Abrahamovych U., Tsyhanyk L., Abrahamovych O., Farmaha M., Romaniuk O.

“…This allows us to define 4 groups of patients: І (16 patients, 28.07 %) – with low content of vitamin D (<30.0 ng/l), preserved osteoblast and osteoclast functions, ІІ (4 patients, 7.02 %) – with the lack of vitamin D (<30.0 ng/l), with preserved osteoblast and osteoclast functions; ІІІ (16 patients, 28.07 %) – with the lack of vitamin D (<30.0 ng/l), with a weakened osteoblast and osteoclast functions; ІУ (19 patients, 33.33 %) – with the lack of vitamin D (<30.0 ng/l), with a weakened osteoblast and osteoclast functions. …”
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Altitudinal patterns of bacterial communities across soil layers in the alpine meadows of the Qinghai-Tibet Plateau by Zhiyuan Chen, Yeteng Xu, Xinyue Wang, Tong Ma, Yang Liu, Xiang Qin, Wei Zhang, Tuo Chen, Guangxiu Liu, Binglin Zhang

“…Microorganisms in the soils of alpine meadows on the Qinghai-Tibet Plateau are pivotal in sustaining ecosystem functionality and stability. The community structure and functional composition of these microbes exhibit pronounced altitudinal variations; however, specific distribution patterns across different soil layers remain inadequately elucidated within alpine meadow ecosystems. …”
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Exploring the role of hyperreflective walls as a biomarker for the management of cystoid macular edema by Zhang-Rong Yang, Chang Li, Dong-Jun Xing, Gao-Xu Wei, Ce-Ce Zhao, Miao Zhou, Xiao-Han Ma, Yi Zhao, Shu Yang, Rong-Guo Yu, Zhi-Qing Li

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CAR-T cells and TRUCKs that recognize an EBNA-3C-derived epitope presented on HLA-B*35 control Epstein-Barr virus-associated lymphoproliferation by Michael Hudecek, Anna Christina Dragon, Katharina Zimmermann, Thomas Nerreter, Deborah Sandfort, Julia Lahrberg, Stephan Klöß, Christina Kloth, Caroline Mangare, Agnes Bonifacius, Sabine Tischer-Zimmermann, Rainer Blasczyk, Britta Maecker-Kolhoff, Barbara Uchanska-Ziegler, Hinrich Abken, Axel Schambach, Britta Eiz-Vesper

“…TÜ165 TRUCKs equipped with inducible IL-12 expression responded even more effectively and released IL-12 recruited additional immune cells which are generally missing in proximity of lymphoproliferation in immunocompromised PTLD patients. …”
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Repurposing FDA-Approved Agents to Develop a Prototype <i>Helicobacter pylori</i> Shikimate Kinase (HPSK) Inhibitor: A Computational Approach Using Virtual Screening, MM-GBSA Calcu... by Abdulaziz H. Al Khzem, Tagyedeen H. Shoaib, Rua M. Mukhtar, Mansour S. Alturki, Mohamed S. Gomaa, Dania Hussein, Nada Tawfeeq, Mohsina Bano, Mohammad Sarafroz, Raghad Alzahrani, Hanin Alghamdi, Thankhoe A. Rants’o

“…All three drug candidates displayed lower HLG values than shikimate, suggesting higher reactivity and more efficient electronic transitions than the reference ligand. …”
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Treatment of acute intracerebral haemorrhage with a Chinese herbal formula (Shengdi Dahuang Decoction): a multicentre, double-blind, randomised, placebo-controlled trial by Feng Wang, Shan Jiang, Tingting Li, Yan Han, Xiaoyu Zhou, Xiaofei Yu, Haiyan Tang, Fan Gong, Dezhi Liu, Zongqi Zhang, Zhihuan Sun, Jingyan Xiang, Yongmei Guo, Mingzhe Wang, Weidong Pan, Jingsi Zhang, Jihan Huang

“…The incidence of adverse events between the two groups did not differ significantly (p&gt;0.05).Conclusions In patients with acute ICH, incorporating SDD as a supplementary intervention alongside guideline-directed treatments may help enhance 90-day functional outcomes; however, more clinical trials are required to further prove its efficacy.Trial registration number NCT04200781.…”
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