Assessing the prognostic and therapeutic value of cuproptosis-related genes in colon adenocarcinoma patients by Zhanhui Ye, Yixian Song, Mengqing Zhu, Fuying Zheng, Wenjie Qin, Wenjie Qin, Xue Li, Pei Wang, Zihua Li, Kequan Chen, Aimin Li

“…Using the Weighted Gene Co-expression Network Analysis (WGCNA) method, we identified the gene module most strongly linked to cuproptosis and conducted functional enrichment analysis to explore the roles of genes within this module in COAD tumorigenesis. …”
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Dip-coating of nylon/chitosan/hydroxyapatite/TiO2 biocoatings to improve durability of metallic prostheses by César A. García-Pérez, Carmina Menchaca-Campos, Jorge Arturo Sandoval-Espino, E. Eduardo Antunez, Alejandro Flores Nicolás, Mayra Alejandra Santillán-Urquiza, Jorge Uruchurtu

“…Results confirmed surface modification due to the interaction between Ti and the biocoating, leading to the formation of a more stable passive layer compared to uncoated Ti. …”
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A non-invasive method for screening mitochondrial diabetes by Hangyu Fang, Hangyu Fang, Xiaoe Li, Shuping Wang, Mei Zhang, Victor Wei Zhang, Chao Xu, Chao Xu, Chao Xu, Chao Xu, Chao Xu, Chao Xu, Chao Xu

“…BackgroundMitochondrial diabetes mellitus (MDM) is a special type of diabetes resulting from functional defects in mitochondria. Its incidence rate is low, and it can often be misdiagnosed as either type 1 or type 2 diabetes in clinical settings. …”
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Can routinely collected primary healthcare data be used to assess Aboriginal children's health and wellbeing longitudinally? A retrospective analysis of electronic medical records... by Catherine Lloyd-Johnsen, John Boffa, Vahab Baghbanian, Rachel Walpole, Shuaijun Guo, Sandra Eades, Anita D'Aprano, Sharon Goldfeld

“…However, crucial data on risk factors, maternal health, and family functioning were either not collected by the service, not provided to the service from external sources, or stored in inaccessible free-text fields. …”
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Evaluating the Effectiveness of Targeted Interventions on the Quality of Life for Patients with Ischemic Stroke by Sultanah Al Harbi, Mohammed Al Ghetami, Mohamed Ahmed, Mohammed Al Althobaiti, Ahmed Newera, Hadeel Al Talhi, Fatmah Alzobidi, Frenk Lee Baldovino, Kamille Bianca Raviz, Leo Medalla, Andyson Mocorro

“…Addressing these challenges necessitates a comprehensive approach that prioritizes improving functional abilities, fostering independence, and enhancing overall well-being of stroke survivors. …”
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Study on Plant Morphological Traits and Production Characteristics of Super High-Yielding Soybean by Xue AO, Ming-hui ZHAO, Qian ZHU, Jie LI, Hui-jun ZHANG, Hai-ying WANG, Cui-mei YU, Chun-hong LI, Xing-dong YAO, Fu-ti XIE, Xiao-ri HAN

“…In summary, super high-yielding soybean cultivars have several main features: suitable plant height, high pod density, good leaf structure with strong functionality, and slow leaf senescence at the late reproductive stage, which is conducive to the accumulation of dry matter and improved yield.…”
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The EIF4EBP1 gene encoding 4EBP1 is transcriptionally upregulated by MYC and linked to shorter survival in medulloblastoma by Laura Hruby, Katerina Schaal, Alberto Delaidelli, Daniel Picard, Christopher Dunham, Oksana Lewandowska, Tobias Reiff, Magalie Larcher, Celio Pouponnot, Poul HB Sorensen, Barak Rotblat, Guido Reifenberger, Marc Remke, Gabriel Leprivier

“…Immunohistochemical evaluation of 4EBP1 protein expression in MB tissues confirmed that high levels of 4EBP1 are associated with poor outcome. Functional analyses revealed that MYC directly regulates EIF4EBP1 promoter activity, providing a mechanism for increased EIF4EBP1 mRNA levels in Group 3 MBs. …”
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Impact of Ovarian Suspensory Ligament Rupture on Surgical Stress in Elective Ovariohysterectomy in Bitches by Pauline Silva dos Santos, Victor Mendes de Oliveira, Keli Cristina Corbellini Oltramari, Vitória Santos Guimarães, Sarah Fernandes, Carla Eduarda dos Santos Ferreira, Agatha Costa Malinski, Vinícius Cardoso de Oliveira, Jéssica Corrêa, Izabelle Moutinho, Dalila Moter Benvegnú, Camila Dalmolin, Gabrielle Coelho Freitas, Fabíola Dalmolin

“…Overall, OSL rupture appears to elicit a slightly more intense surgical stress response than the non-rupture technique.…”
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A fusion ORF3a-E subgenomic RNA involved in SARS-CoV-2 infection efficacy by influencing cellular protein synthesis by Yifan Zhang, Jing Li, Xinglong Zhang, Xin Zhang, Jiali Li, Heng Li, Heng Li, Heng Li, Xin Zhao, Xin Zhao, Xin Zhao, Zihan Zhang, Yingyan Li, Keqi Chen, Shasha Peng, Haijing Shi, Haijing Shi, Haijing Shi, Longding Liu, Longding Liu, Longding Liu

“…Subgenomic RNAs (sgRNAs) are discontinuous transcription products of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that are involved in viral gene expression and replication, but their exact functions are still being studied. Here, we report the identification of a nested ORF3a-sgRNA, the fusion ORF3a-E-sgRNA, which is involved in the infection process of SARS-CoV-2. …”
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Identification of stemness subtypes and prognostic modeling in thyroid cancer: the critical role of DPYSL3 in tumor progression and immune microenvironment by Jialong Yu, Wei Luo, Guangwei Xu, Mei Tao, Yuqi Wang, Qiman Dong, Linfei Hu, Xiukun Hou, Jingzhu Zhao, Dapeng Li, Songfeng Wei, Xianhui Ruan, Xiangqian Zheng

“…This model revealed that patients in the high-risk group had lower progression-free survival (PFS) but may benefit more from immune checkpoint blockade therapy, as indicated by TIME analysis. …”
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Unveiling Electron‐Phonon and Electron‐Magnon Interactions in the Weak Itinerant Ferromagnet LaCo2P2 by D. Yu. Usachov, K. Ali, G. Poelchen, M. Mende, S. Schulz, M. Peters, K. Bokai, I. Yu. Sklyadneva, V. Stolyarov, E. V. Chulkov, K. Kliemt, S. Paischer, P. A. Buczek, R. Heid, F. Hempel, M. Ruesing, A. Ernst, C. Krellner, S. V. Eremeev, D. V. Vyalikh

“…Abstract Studying and understanding many‐body interactions, particularly electron‐boson interactions, is essential for a deeper elucidation of fundamental physical phenomena and the development of novel material functionalities. Here, this aspect is explored in the weak itinerant ferromagnet LaCo2P2 by means of momentum‐resolved photoelectron spectroscopy (ARPES) and first‐principles calculations. …”
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Identification of the Cold-Related Genes COLD11 and OsCTS11 via BSA-seq and Fine Mapping at the Rice Seedling Stage by Bian Wu, Minghui Fu, Jinghua Du, Mengjing Wang, Siyue Zhang, Sanhe Li, Junxiao Chen, Wenjun Zha, Changyan Li, Kai Liu, Huashan Xu, Huiying Wang, Shaojie Shi, Yan Wu, Peide Li, Aiqing You, Lei Zhou

“…According to the reported functional variation of COLD11, Nipponbare (TCG + 3GCG)×2 presented more GCG repeats in the 1st exon than WD16343 (TCG + 3GCG), partially explaining the difference in cold tolerance between the parents. …”
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Novel photodynamic therapy using two-dimensional NiPS3 nanosheets that target hypoxic microenvironments for precise cancer treatment by Wu Zongze, Liu Quan, Wageh Swelm, Sun Zhe, Al-Hartomy Omar A., Al-Sehemi Abdullah G., Yan Lesen, Chen Jiaojuan, Zhang Wenjian, Yang Jilin, Zhang Han, Liu Liping

“…Modified with triphenylphosphine (TPP) and based on density functional theory (DFT) calculations and experimental data, the NiPS3@TPP nano-system underwent targeted action toward mitochondria. …”
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Expert consensus on the technical specifications of the in vitro skin penetration test of cosmetic product by Franz diffusion cell by Bingwen Liang, Liling Zhou, Chuanbin Wu, Liang Fang, Lisheng Wang, Lihua Peng, Peng Shu, Lifeng Tang, Yu Bei, Xiaodong Cui, Xiaojia Chen, Yuan Gao, Chong Han, Yan Jia, Huaqing Lin, Yifang Li, Ying Liu, Yiguang Li, Zhiwei Li, Zixiu Liu, Shaohua Ren, Jun Shi, Wanyang Sun, Lijuan Tian, Qun Wang, Yuan Wang, Yuehong Xu, Ming Zeng, Quangang Zhu, Shu Zhang, Yifan Zhang, Qi Xiang

“…Materials and Methods: To standardize the in vitro diffusion cell test technique for transdermal penetration of functional cosmetic ingredients, the Transdermal Drug Delivery Professional Committee of the World Federation of Societies of Traditional Chinese Medicine has organized many discussions among experts. …”
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Rehabilitation effect on psycho-emotional well-being in women with surgically treated vulvar cancer: a randomised controlled trial by Blinov V. Dmitry, Antonina G. Solopova, Elena V. Gameeva, Nazim G. Badalov, Vsevolod N. Galkin, Mikhail A. Eremushkin, Alexandra M. Stepanova, Alexander E. Ivanov, Olga S. Gridasova

“…Surgical treatment of vulvar cancer (VC) entails mental and somatic disturbances due to pain, body image changes, and sexual dysfunction, which are closely associated with impaired social functioning and reduced overall quality of life. However, the results evaluating the impact of rehabilitation programmes on various components of quality of life in these patients remain limited. …”
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Clinical, electromyographic, and biophysical characterization of the rare Nav1.4 channel mutation SCN4A L1436P by François Charles Wang, François Charles Wang, Olivier Bouquiaux, Olivier Bouquiaux, Isabelle Lievens, Bernard Lakaye, Laura Vandries, Margaux Poleur, Samira Abdou Ide, Nurcan Inci, Vincent Seutin

“…Our experimental data indicates a relatively milder biophysical phenotype for L1436P as compared to R1448H, which becomes more pronounced at lower temperatures, consistent with the clinical phenotype of a majority of patients.…”
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Chemical magnetic field-assisted batch polishing method of 316L stainless steel by Fukang Yin, Chenchun Shi, Zikang Huang, Ke Wu, Jinbang Li, Chunjin Wang

“…This work is capable of providing valuable reference undoubtedly for batch precision polishing of 316L stainless steel and other significant functional materials.…”
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Efficacy and safety of combination therapy with lenvatinib and pembrolizumab in elderly patients with advanced endometrial cancer by M. V. Volkonskiy, A. A. Akopyan, T. A. Zhelezkova, R. S. Zhikhorev, E. P. Krasnorutskaya, N. R. Abidova, T. A. Makarkina, M. O. Skorina, V. M. Filippova, I. A. Luev, Yu. V. Vasilyeva, G. D. Malina, L. P. Veshkina, B. L. Nersesyan

“…Additional studies are required to evaluate the efficacy and safety of the combination therapy of lenvatinib and pembrolizumab in patients with a more severe functional status.…”
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Lanthanide bioadsorption by the extremophile Exiguobacterium sp.: utilizing microbial extracellular polysaccharides for high-value element recovery by Karem Gallardo, Génesis Serrano, Rodrigo Castillo, Sebastián Michea, Julio I. Urzúa, Dayana Arias, Francisco Remonsellez, Francisco Remonsellez

“…ATR-FTIR analysis identified hydroxyl and carbonyl groups as key functional groups involved in metal binding, with notable spectral changes after REE exposure. …”
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Chronic Tic Disorders in Youth: Clinical Phenotypes and Response to Pharmacological Treatment with Aripiprazole by Francesca Falcone, Stefano Berloffa, Gianluca Sesso, Antonio Narzisi, Elena Valente, Valentina Viglione, Gabriele Masi, Annarita Milone, Pamela Fantozzi

“…Conclusions: Comorbid neurodevelopmental disorders, such as ADHD or ASD, result in worse emotional and behavioral functioning in patients with tic disorders. ADHD–ASD interaction may be linked to more internalizing symptoms and autistic behaviors. …”
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