Membran Alginat Padina sp. - Polietilen Glikol (AP-PEG): Preparasi, Karakterisasi dan Aplikasinya sebagai Enkapsulan by Herlina Herlina, Aswin Falahudin, Irfan Gustian, Agus Martono H. Putranto, Morina Adfa, Salprima Yudha S

“…This is based on the need for new materials with more favorable characteristics and can be used in specific applications. …”
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Single-cell transcriptome analysis reveals the malignant characteristics of tumour cells and the immunosuppressive landscape in HER2-positive inflammatory breast cancer by Juan Huang, Yongwei Zhu, Wenjing Zeng, Yulong Zhang, Weizhi Xia, Fan Xia, Liyu Liu, Kuansong Wang, Yidi Guan, Taohong Shen, Bingjian Jiang, Lunquan Sun, Ayong Cao, Shouman Wang, Zhi Li

“…By performing a cellular interaction analysis, we revealed that PTN molecules were significantly overexpressed in HER2 + IBC tumour cells and that the cellular interactions mediated by these molecules were strongly correlated with the functional polarisation of the cellular components in the TME. …”
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DEFORMATION OF THE MELODRAMA GENRE IN UKRAINIAN POSTMODERN LITERATURE: IREN ROZDOBUDKO AND NATALIA HURNYTSKA by Olha O. Lilik, Olena V. Sazonova

“…Accordingly, the heroine of the novel by Irene Rozdobudko appears more diverse, while the interests of the heroine of the novel by N. …”
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Comprehensive evaluation of coding region point mutations in microsatellite‐unstable colorectal cancer by Johanna Kondelin, Kari Salokas, Lilli Saarinen, Kristian Ovaska, Heli Rauanheimo, Roosa‐Maria Plaketti, Jiri Hamberg, Xiaonan Liu, Leena Yadav, Alexandra E Gylfe, Tatiana Cajuso, Ulrika A Hänninen, Kimmo Palin, Heikki Ristolainen, Riku Katainen, Eevi Kaasinen, Tomas Tanskanen, Mervi Aavikko, Minna Taipale, Jussi Taipale, Laura Renkonen‐Sinisalo, Anna Lepistö, Selja Koskensalo, Jan Böhm, Jukka‐Pekka Mecklin, Halit Ongen, Emmanouil T Dermitzakis, Outi Kilpivaara, Pia Vahteristo, Mikko Turunen, Sampsa Hautaniemi, Sari Tuupanen, Auli Karhu, Niko Välimäki, Markku Varjosalo, Esa Pitkänen, Lauri A Aaltonen

“…MSI colorectal cancers (CRCs), however, also contain more point mutations than microsatellite‐stable (MSS) tumors, yet they have not been as comprehensively studied. …”
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High-affinity agonists reveal recognition motifs for the MRGPRD GPCR by Chunyu Wang, Yongfeng Liu, Marion Lanier, Adam Yeager, Isha Singh, Ryan H. Gumpper, Brian E. Krumm, Chelsea DeLeon, Shicheng Zhang, Marcus Boehm, Richard Pittner, Alain Baron, Lisa Dvorak, Corinne Bacon, Brian K. Shoichet, Esther Martinborough, Jonathan F. Fay, Can Cao, Bryan L. Roth

“…The most potent small-molecule agonist of MRGPRD reported so far is β-alanine, with an affinity in the micromole range, which largely restricts its functional study. Here, we report two MRGPRD agonists, EP-2825 and EP-3945, that are approximately 100-fold more potent than β-alanine and determine the structures of MRGPRD-Gq in complex with EP-2825 and EP-3945, respectively. …”
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Lilac (Syringa oblata) genome provides insights into its evolution and molecular mechanism of petal color change by Bo Ma, Jing Wu, Tian-Le Shi, Yun-Yao Yang, Wen-Bo Wang, Yi Zheng, Shu-Chai Su, Yun-Cong Yao, Wen-Bo Xue, Ilga Porth, Yousry A. El-Kassaby, Ping-Sheng Leng, Zeng-Hui Hu, Jian-Feng Mao

“…Our results provide a foundation for functional study and molecular breeding in lilac.…”
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Plasticity enhancement in metallic glasses via aging-assisted ultrasonic vibrations by Jianyu Chen, Shuai Ren, Zhe Chen, Jie Dong, Zhichao Lu, Jiahua Zhu, Lixing Zhu, Yangguang Zhan, Xingran Zhao, Wenxue Wang, Shenghao Zeng, Jing Xiao, Sajad Sohrabi, Xiong Liang, Ke Yang, Dong Ma, Jiang Ma

“…This intriguing plasticity enhancement results from a UV-induced higher-energy state, as evidenced by structural enthalpy recovery, boson peak restoration, and a more disordered structure revealed by the pair distribution functions. …”
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Enhancing <i>Bacillus thuringiensis</i> Performance: Fertilizer-Driven Improvements in Biofilm Formation, UV Protection, and Pest Control Efficacy by Fan Zhao, Yufei Mao, Jiahong Yang, Sheng Yang, Xiong Guan, Zixuan Wang, Tianpei Huang

“…Bacterial biofilms provide protection for Bt, enhancing its survival and functionality in the environment. However, the mechanisms by which fertilizers regulate the characteristics of microbial pesticides and enhance biofilm formation are not well understood. …”
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Long-term Metformin Alters Gut Microbiota and Serum Metabolome in Coronary Artery Disease Patients After Percutaneous Coronary Intervention to Improve 5-year Prognoses: A Multi-omi... by Ruilin Zhou, Qingyang Wu, Hao Qian, Liang Wang, Guangcheng Liu, Bin Zhang, Wei Wu, Shuyang Zhang

“…Metformin tended to have more positive effects on the commensal flora and metabolic profiles, which may explain its beneficial effects on cardiovascular health. …”
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Initial experience of laparoendoscopic single-site radical prostatectomy with a novel purpose-built robotic system by Zheng Wang, Chao Zhang, Chengwu Xiao, Yang Wang, Yu Fang, Baohua Zhu, Shouyan Tang, Xiaofeng Wu, Hong Xu, Yi Zhou, Lingfen Wu, Zhenjie Wu, Bo Yang, Yi He, Yi Liu, Linhui Wang

“…The demographic and baseline data, surgical, oncological, and functional outcomes as well as follow-up data were recorded. …”
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Diversity and Distribution of Fungi in the Marine Sediments of Zhanjiang Bay, China by Menghan Gao, Bihong Liu, Jianming Li, Yunyan Deng, Yulei Zhang, Ning Zhang, Feng Li, Changling Li, Xianghu Huang, Zhangxi Hu

“…Additionally, the FUNGuild database was employed to assess the potential functional traits of fungi. A total of 1242 ASV sequences, affiliated to 144 genera and five phyla, were identified. …”
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Bioremediation of malachite green dye using Sargassum wightii seaweed and its biological and physicochemical characterization by Kaliaperumal Kumaravel, Aboobacker Janeeba, Dhanapal Vigneshpriya, Gayathri Abinaya, Subramanian Kumaran, Suresh Arumugam, Elumalai Sanniyasi, Sampath Shobana, Devanesan Sandhanasamy, AlSalhi Mohamad S., Asaithambi Perumal

“…Degradation of such dyes using a biological treatment like microbe and plant-based remediation is an eco-friendly approach and more feasible than the physical and chemical treatment processes. …”
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Clinical and Ultrasound Evaluation of Hemiplegic Shoulder Pain in Stroke Patients: A Longitudinal Observational Study Starting in the First Hours After Stroke by Filippo Cotellessa, William Campanella, Luca Puce, Maria Cesarina May, Marta Ponzano, Riccardo Picasso, Matteo Mordeglia, Davide Subbrero, Ester Cecchella, Laura Mori, Davide Sassos, Massimo Del Sette, Matteo Formica, Carlo Trompetto

“…Ultrasound findings at T2 revealed that adhesive capsulitis and glenohumeral subluxation were significantly more frequent in HSP patients (<i>p</i> < 0.05). …”
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New insights into the evolution analysis of trihelix gene family in eggplant (Solanum melongena L.) and expression analysis under abiotic stress by Yanhong Lan, Fangyi Gong, Chun Li, Feng Xia, Yifan Li, Xiaojun Liu, Duchen Liu, Genyun Liang, Chao Fang, Peng Cai

“…In order to comprehensively investigate the functions of trihliex genes in eggplant development and the abiotic stress response, we conducted an extensive analysis of the trihliex gene family in the eggplant genome. …”
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Ruminococcus gnavus and Biofilm Markers in Feces From Primary Bile Acid Diarrhea Patients Indicate New Disease Mechanisms and Potential for Diagnostic Testing by Evette B.M. Hillman, Danielle Carson, Julian R.F. Walters, Martin Fritzsche, Ryan Mate, Katie E. Chappell, Elena Chekmeneva, Maria Gomez Romero, Stephen J. Lewis, Sjoerd Rijpkema, Elizabeth M.H. Wellington, Ramesh Arasaradnam, Gregory C.A. Amos

“…Bile acidtransforming genes (baiA, baiB, hdhA) were more abundant in BAD samples (P ≤ .0012). Most fecal bile acids, including iso-bile acids and intermediates, were higher in BAD. …”
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Design and methods of an adaptive trial to test comparative effectiveness of readmission reduction approaches following infection and sepsis hospitalizations (ACCOMPLISH) by Kristin Mayes, Victor B. Talisa, Adelina Malito, Florian B. Mayr, Kelly Williams, Kalpana Char, Richard Wadas, Elizabeth Lorenzi, Kert Viele, Rana Awdish, Derek C. Angus, Chung-Chou Ho Chang, Sachin Yende

“…Secondary endpoints, such as functional status and health-related quality of life, will be measured at baseline and 90 days. …”
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Direct-fed microbials optimize ruminal fermentation, microbial ecosystem and milk quality to enhance the lactation performance of Sanhe dairy cows by Aoyu Jiang, Zixin Liu, Ziyan Yang, Shizhe Zhang, Jian Wu, Chuanshe Zhou, Zhiliang Tan

“…In predictive analysis of microbial functional genes, the treatment group was enriched with more genes encoding hemicellulose-degrading enzymes such as GH10, GH30, and GH67, while the relative abundance of genes encoding enzymes that metabolize ammonia was increased. …”
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Enhanced fetal hemoglobin production via dual-beneficial mutation editing of the HBG promoter in hematopoietic stem and progenitor cells for β-hemoglobinopathies by Prathibha Babu Chandraprabha, Manoj Kumar K. Azhagiri, Vigneshwaran Venkatesan, Wendy Magis, Kirti Prasad, Sevanthy Suresh, Aswin Anand Pai, Srujan Marepally, Alok Srivastava, Kumarasamypet Murugesan Mohankumar, David I. K. Martin, Saravanabhavan Thangavel

“…To recapitulate this natural phenomenon, the most coveted gene therapy approach is to edit the regulatory sequences of HBG1/G2 to reactivate them. By editing more than one regulatory sequence in the HBG promoter, the production of fetal hemoglobin (HbF) can be significantly increased. …”
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Single-nucleus RNA sequencing reveals the specific molecular signatures of myeloid cells responding to brain injury after microglial replacement by Xiao-Yi Xiong, Xiao-Yi Xiong, Xiao-Yi Xiong, Haicheng Yuan, Ying Mu, Yi He, Fang Xie, Xiao-Shuang Feng, Jia-Xin Xie, Xin-Ru Pan, Yu-Fei Wang, Jian Gong, Xiaoming Zheng, Peng-Fei Wang

“…Both MG and Mo/MΦ experience modification of immune responses after microglial repopulation, with more prominent changes in MG. Gene Ontology (GO) analysis showed that one term directly related to the “immune response” was shared between upregulated genes in Rep-MG and Rep-Mo/MΦ, while the other terms related to immune functions and other biofunctions were different between Rep-MG and Rep-Mo/MΦ, indicative of significantly different immune responses to brain injury between MG and MΦ. …”
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Anatomical Variants in Pancreatic Irrigation and Their Clinical Considerations for the Pancreatic Approach and Surrounding Structures: A Systematic Review with Meta-Analysis by Juan José Valenzuela-Fuenzalida, Camila Ignacia Núñez-Castro, Valeria Belén Morán-Durán, Pablo Nova-Baeza, Mathias Orellana-Donoso, Alejandra Suazo-Santibáñez, Alvaro Becerra-Farfan, Gustavo Oyanedel-Amaro, Alejandro Bruna-Mejias, Guinevere Granite, Daniel Casanova-Martinez, Juan Sanchis-Gimeno

“…To enhance outcomes, it is recommended to develop more accurate imaging tools for pre-surgical analysis, necessitating ongoing research in this area.…”
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