Metabolomics and network pharmacology–guided analysis of TNF-α expression by Argemone mexicana (Linn) targeting NF-kB the signalling pathway in cancer cell lines by Sunanda Kulshrestha, Anjana Goel, Subhadip Banerjee, Rohit Sharma, Mohammad Rashid Khan, Kow-Tong Chen, Kow-Tong Chen

“…Network pharmacology analysis used Binding DB, STRING, DAVID, and KEGG for data mining to evaluate predicted compounds using functional annotation analysis. Cytoscape 3.2.1 created “neighbourhood approach” and networks. …”
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Urban Hierarchy Migration Model and Impact Mechanism of Graduates Admitted to the Guangdong Provincial Civil Service Examination by Wu Jinghao, Liu Ye, Tang Honglin

“…Personal attributes and job requirements have a relatively significant impact; the better the personal attributes and the higher the job requirements, the more likely they are to migrate up the urban hierarchy. …”
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Enhanced Teleoperation of Robotic Arms Through Master-Slave Configuration With Multithreading by Ahmad Faiz Fawzan Ahmad Zainudin, Mohd Hairi Mohd Zaman, Mohd Faisal Ibrahim, Mohd Asyraf Zulkifley, M. Marzuki Mustafa

“…Moreover, the dissimilarities in design, functionality, and control mechanisms between the master device and the slave robot arm introduce additional layers of complexity, making the operation and synchronization of the system more challenging. …”
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Complicações em reconstrução de mama com retalho pediculado do músculo reto abdominal transverso Complications in breast reconstruction using a transverse rectus abdominis myocutan... by Carolina Garzon Paredes, Salustiano Gomes de Pinho Pessoa, Dayanne Nogueira de Amorim, Diego Tomaz Teles Peixoto, Jéssica Silveira Araújo

“…Although reconstruction using the TRAM flap is the most widely used technique that yields the best aesthetic and functional results, it is associated with certain complications. …”
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Chronic stress is associated with altered gut microbiota profile and relevant metabolites in adolescents by Li Ying, Wang Yuhao, He Yafang, Lan Jiao, Dang Lina, Song Qinze, Yang Chenghai, Zhao Shaoxiong, Gu Yuexi, Shen Mingwang, Cai Zelin, Wang Chuangchuang, Guo Zihan, Liu Xin, Ma Lu, Zhang Lei

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Integrated single-cell analysis reveals distinct epigenetic-regulated cancer cell states and a heterogeneity-guided core signature in tamoxifen-resistant breast cancer by Kun Fang, Aigbe G. Ohihoin, Tianxiang Liu, Lavanya Choppavarapu, Bakhtiyor Nosirov, Qianben Wang, Xue-Zhong Yu, Sailaja Kamaraju, Gustavo Leone, Victor X. Jin

“…Methods In this study, we conducted an integrated analysis combining scRNA-seq and scATAC-seq on more than 80,000 breast tissue cells from two normal tissues (NTs), three primary tumors (PTs), and three tamoxifen-treated recurrent tumors (RTs). …”
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Spatial Correlates of Dementia and Disability After Intracerebral Hemorrhage by Yutong Chen, Cyprien A. Rivier, Samantha A. Mora, Victor Torres Lopez, Sam Payabvash, Kevin Sheth, Andreas Harloff, Guido J. Falcone, Jonathan Rosand, Ernst Mayerhofer, Christopher D. Anderson

“…These insights have the potential to enhance clinical prognostic models for patients with ICH, facilitating more precise predictions of outcomes based on hemorrhage location.…”
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Investigation and analysis on the status quo of nurses' knowledge of urinary incontinence and their training needs in the region (上海市某区域护士尿失禁知识认知现状与培训需求的调查分析)... by YUAN Hongyan (袁红艳), XU Fanglei (许方蕾), TANG Ailing (汤爱玲), GE Yan (葛颜), DONG Li (董里)

“…Nurses in level II hospitals (29. 82%) preferred to strengthen training on functional exercise, such as rehabilitation and guidance of pelvic floor muscles. …”
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Biomarkers and Mental Disorders: A Relevance Analysis Using a Random Forest Algorithm by Joice M. A. Rodolpho, Krissia F. Godoy, Bruna D. L. Fragelli, Jaqueline Bianchi, Fernanda O. Duarte, Luciana Camillo, Gustavo B. Silva, Paulo H. M. Andrade, Juliana A. Prado, Carlos Speglich, Fernanda F. Anibal

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Benefícios da atenção domiciliar ao idoso portador de dano crônico: revisão sistemática da literatura [Benefits of home care to the elderly with chronic diseases: systematic litera... by Carolina Baltar Day, Lisiane Paskulin

“…All studies compared home care with other attention. There were more male in the studies samples and Heart Failure as basis disease. …”
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Identification and verification of biomarkers associated with neutrophils in acute myocardial infarction: integrated analysis of bulk RNA-seq, expression quantitative trait loci, a... by Guoqing Liu, Xiangwen Lv, Jiahui Qin, Xingqing Long, Miaomiao Zhu, Chuwen Fu, Jian Xie, Peichun He

“…Genes with correlation coefficients >0.7 with neutrophils were selected, and their representativeness was confirmed by functional enrichment analysis. Weighted gene co-expression network analysis (WGCNA) was performed to screen for AMI-related modular genes. …”
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Building Energy Optimization Using an Improved Exponential Distribution Optimizer Based on Golden Sine Strategy Minimizing Energy Consumption Under Uncertainty by Mohammad Ali Karbasforoushha, Mohammad Khajehzadeh, Suraparb Keawsawasvong, Lapyote Prasittisopin, Thira Jearsiripongkul

“…Therefore, while the stochastic model offers a more realistic system design, it also highlights the challenge of managing uncertainty in building energy optimization.…”
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Long-term Results of Treatment of Patients with Non-proliferative Diabetic Retinopathy Angioprotectors by I. V. Vorobyeva

“…Modern diagnostics, including the definition of the ophthalmological examination: visual acuity, central retinal thickness, macular light sensitivity as well as the definition and stabilization of important biochemical indicator of blood glycated hemoglobin (HbA1C) will not prevent the development of more severe stages of DR. In patients with type 2 diabetes without signs of diabetic retinopathy (DR0), while maintaining high visual acuity and normal retinal thickness showed a significant and meaningful reduction in the light sensitivity of the retina of the macula, which allows to start treatment with redox Doxi-Hem® at the preclinical stage (DR0).…”
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Naimat Khana: The Narrative of Human's Mythological and Surreal Structure by Suryya Siddique

“…What makes <em>Nimatkhana</em> remarkable is its dualistic nature - it functions simultaneously as mythological allegory and psychological mirror, reflecting both our transcendental history and primal human truths. …”
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Putting measurement-based care into action: a multi-method study of the benefits of integrating routine client feedback in coordinated specialty care programs for early psychosis by Piper Meyer-Kalos, Grace Owens, Melissa Fisher, Lionel Wininger, Anne Williams-Wengerd, Kimberleigh Breen, Josephine Pita Abate, Ariel Currie, Nathan Olinger, Sophia Vinogradov

“…The feedback report group engaged in significantly more sessions of Supported Employment and Education (SEE), case management, and peer support, and fewer medication visits over the first 6 months of treatment. …”
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The role of ultra-high field MRI and image processing in the presurgical workup in MRI-negative focal epilepsy: A validated 7T MRI case study by Daniel Uher, Gerhard S. Drenthen, Christianne M. Hoeberigs, Rick H.G.J. van Lanen, Albert J. Colon, Roy A.M. Haast, Vivianne H.J.M. van Kranen-Mastenbroek, Guido Widman, Paul A.M. Hofman, Louis G. Wagner, Jan C. Beckervordersandforth, Jacobus F.A. Jansen, Olaf E.M.G. Schijns, Walter H. Backes

“…However, abnormalities were more conspicuous on 7 T. Resting-state functional MRI metrics, particularly regional homogeneity and fractional amplitude of low-frequency fluctuations, demonstrated significantly increased values in both a MAP18-defined region of interest and the entire resected area compared to a healthy control group (p < 0.05). …”
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Immune correlates of early clearance of Mycobacterium tuberculosis among tuberculosis household contacts in Indonesia by Todia P. Setiabudiawan, Lika Apriani, Ayesha J. Verrall, Fitria Utami, Marion Schneider, Agnes R. Indrati, Pauline P. Halim, Paulina Kaplonek, Hadar Malca, Jessica Shih-Lu Lee, Simone J. C. F. M. Moorlag, L. Charlotte J. de Bree, Vera P. Mourits, Leo A. B. Joosten, Mihai G. Netea, Bachti Alisjahbana, Ryan P. McNamara, Galit Alter, Arjan van Laarhoven, James E. Ussher, Katrina Sharples, Valerie A. C. M. Koeken, Philip C. Hill, Reinout van Crevel

“…Neither circulating concentrations of Mtb-specific antibodies nor functional antibody activity associated with IGRA status at baseline or follow-up. …”
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CRISPR/Cas9 a genomic engineering technology for treatment in ALS mouse models by Hamid Khan, Hammad Riaz, Adeel Ahmed, Mubin Mustafa Kiyani, Sahibzada Muhammad Jawad, Syed Shahab Ud Din Shah, Turki Abualait, Fawaz Al-hussain, Hong-Tao Li, Shahid Bashir

“…Nearly 20 gene mutations are associated with ALS, with SOD1, FUS, TARDBP, and C9orf72 mutations being more common. Ninety percent of ALS cases are related to sporadic ALS, while the remaining 10 % are associated with familial ALS. …”
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Uncharted territory: the arrival of Psychoda albipennis (Zetterstedt, 1850) (Diptera: Psychodidae) in Maritime Antarctica by Jordan Hernandez-Martelo, Jordan Hernandez-Martelo, Jordan Hernandez-Martelo, Jordan Hernandez-Martelo, Tamara Contador, Tamara Contador, Tamara Contador, Sanghee Kim, Carla Salina, Claudia S. Maturana, Claudia S. Maturana, Manuel Suazo, Peter Convey, Peter Convey, Peter Convey, Peter Convey, Peter Convey, Hugo A. Benítez, Hugo A. Benítez, Hugo A. Benítez

“…While it is unclear if P. albipennis is capable of long-distance dispersal, adult psychodid flies are known to travel more than 90 m from their emergence sites, and up to 1.5 km with wind assistance. …”
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Epigenome profiling reveals distinctive regulatory features and cis-regulatory elements in pepper by Hongji Yang, Guorong Yu, Zhidong Lv, Tonghui Li, Xi Wang, Ying Fu, Zhangsheng Zhu, Guangjun Guo, Hang He, Ming Wang, Guochen Qin, Feng Liu, Zhenhui Zhong, Yan Xue

“…While the large and complex genome of pepper severely hampered the understanding of its functional genome, it also indicates a rich yet unexplored reservoir of regulatory elements (REs). …”
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