Regulating periodontal disease with smart stimuli-responsive systems: Antimicrobial activity, immunomodulation, periodontium regeneration by Guang-Liang Su, Yu-Jun Peng, Hong-Ze Ruan, Juan Cheng, Tian Deng, Yu-Feng Zhang

“…In recent years, intelligent biomaterials with stimuli-responsive characteristics have garnered more attention due to their unique advantages. These materials can respond to specific physiological signals or external stimuli, enabling precise release of functional agents. …”
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Decoding chromosomal instability insights in CRC by integrating omics and patient-derived organoids by Federica Papaccio, Manuel Cabeza-Segura, Blanca García-Micó, Francisco Gimeno-Valiente, Sheila Zúñiga-Trejos, Valentina Gambardella, María Fernanda Gutiérrez‐Bravo, Carolina Martinez‐Ciarpaglini, Pilar Rentero‐Garrido, Tania Fleitas, Susana Roselló, Juan Antonio Carbonell-Asins, Marisol Huerta, David Moro-Valdezate, Desamparados Roda, Noelia Tarazona, Manuel M. Sánchez del Pino, Andrés Cervantes, Josefa Castillo

“…We integrated the RNA-seq and mass spectrometry-based proteomics data from PDOs in a functional interaction network to identify the significantly dysregulated processes in CIN. …”
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Thinking- Skins by Jens Böke

“…In the sense of an internet of façade functions, the automated adaptive façade functions ventilation, sun protection as well as heating and cooling are implemented in decentrally organized modules. …”
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Strategies for specific multimodal imaging of cancer-associated fibroblasts and applications in theranostics of cancer by Li Wen, Chengxue He, Yanhui Guo, Nina Zhou, Xiangxi Meng, Yuwen Chen, Cheng Ma, Hua Zhu, Zhi Yang, Lei Xia

“…At present, small-molecule radiotracer targeting FAP with high specificity exhibit limited functionality, which hinders the integration of theranostics as well as multifunctionality. …”
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The neuropeptide sulfakinin is a peripheral regulator of insect behavioral switch between mating and foraging by Hong-Fei Li, Bao Dong, Yuan-Yuan Peng, Hao-Yue Luo, Xiao-Lan Ou, Zheng-Lin Ren, Yoonseong Park, Jin-Jun Wang, Hong-Bo Jiang

“…Here, we show that the behavioral switch between foraging and reproduction is associated with changes in antennal sensitivity. Starved flies became more sensitive to food odors while suppressing their response to opposite-sex pheromones. …”
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Host Cell Signalling and Leishmania Mechanisms of Evasion by Marina Tiemi Shio, Kasra Hassani, Amandine Isnard, Benjamin Ralph, Irazu Contreras, Maria Adelaida Gomez, Issa Abu-Dayyeh, Martin Olivier

“…Collectively, a better understanding of the evasion mechanisms utilized by Leishmania parasite could help to develop more efficient antileishmanial therapies in the near future.…”
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Enhanced B cell electroporation efficiency via inhibition of DNA-induced apoptosis and pyroptosis with pan-caspase inhibitor by Gui-Lin Yang, Deng-Gao Wang, Xiang Zhao, De-Long Hao, Zhu-Qin Zhang, De-Pei Liu

“…B cells have immense potential as gene therapy carriers because of their ability to secrete therapeutic proteins and mediate immunological memory and tolerogenic functions. However, efficient gene delivery into primary B cells remains a challenge, as DNA electroporation frequently induces significant cell death. …”
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Integrating Tumor Hypoxic Sensing and Photothermal Therapy Using a Miniaturized Fiber‐Optic Theranostic Probe by Fangzhou Jin, Zhiyuan Xu, Wei Wang, Zhongyuan Cheng, Yang Wu, Zesen Li, Enlai Song, Xu Yue, Yong Kang Zhang, Wei Li, Youzhen Feng, Donglin Cao, Dongmei Zhang, Minfeng Chen, Xiangran Cai, Yang Ran, Bai‐Ou Guan

“…Herein, an integrated fiber‐optic theranostic (iFOT) probe is developed that merges tumor microenvironment sensing and photothermal therapy by functionalizing the fiber with graphene/gold nanostar hybrid materials and hypoxic‐responsive fluorophores. …”
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Exploring ribosome biogenesis in lung adenocarcinoma to advance prognostic methods and immunotherapy strategies by Zipei Song, Yuheng Wang, Miaolin Zhu, Pengpeng Zhang, Zhihua Li, Xin Geng, Xincen Cao, Jianan Zheng, Jianwei Tang, Liang Chen

“…The low-RBS group exhibited a tumor microenvironment (TME) more favorable for efficient immune monitoring and reaction, higher responsiveness to immunotherapy, and a better prognosis. …”
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Shotgun metagenomic sequencing reveals the influence of artisanal dairy environments on the microbiomes, quality, and safety of Idiazabal, a raw ewe milk PDO cheese by Gorka Santamarina-García, Min Yap, Fiona Crispie, Gustavo Amores, Cathy Lordan, Mailo Virto, Paul D. Cotter

“…Results The results revealed diverse microbial ecosystems across sample types, comprising more than 1300 bacterial genera and 3400 species. …”
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COVID-19 Pandemic Response Capacity Status of West Africa by Virgil Kuassi Lokossou, Basil Benduri Kaburi, Delia Akosua Bandoh, Edgard Marius Ouendo, Aboubacar Ouédraogo, Franklin Aseidu-Bekoe, Samuel Kaba Akoriyea, Issiaka Sombié, Donmozoun Télesphore Somé, Ermel Amewsue Johnson, Ernest Kenu

“…All (100%) of the 15 states had functional incident management systems; rapid response teams; and at least two of the three tiers of field epidemiology workforce. …”
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Structure-dependent degradation of milk oligosaccharides by newly isolated intestinal commensal bacterial strains from suckling piglets and rabbits by Mathilde Rumeau, Sead Chadi, Frederic Pepke, Martin Beaumont, Cláudia M. Vicente, Agathe Juppeau, Céline Vandecasteele, Laurent Cauquil, Géraldine Pascal, Philippe Langella, Christelle Knudsen, Sylvie Combes, Rebeca Martín

“…This study aims to investigate in vitro the functional relationship between the structural variability of milk oligosaccharides and the metabolic capacities of newly intestinal commensal bacteria isolated from suckling rabbits and piglets. …”
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Identification of anoikis-related molecular patterns and the novel risk model to predict prognosis, tumor microenvironment infiltration and immunotherapy response in bladder cancer by Luochen Zhu, Feng Xiao, Yi Hou, Shenjun Huang, Yanyan Xu, Xiaohong Guo, Xinwei Dong, Chunlu Xu, Xiaolei Zhang, Haijuan Gu

“…In addition, representative genes were evaluated using immunohistochemistry in clinical specimens, and in BLCA cell lines, functional experiments were performed to determine the biological behavior of hub gene PLOD1.ResultTwo definite anoikis subgroups were identified. …”
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Comparative analysis of milk production, composition, and plasma metabolomics across various dairy goat breeds in Yunnan Province, China by Xun Xiang, Hua Chang, Samiullah Khan, Ibrar Muhammad Khan, Feiyan Zhu, Linfu Yang, Gang Duan, Jiming Li, Nourhan Nassar, Feiyan Dai, Huaming Mao

“…A total of 17 metabolites, including 12 metabolic pathways and 7 functional classifications, were investigated using the KEGG platform. …”
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Rheumatoid arthritis and psoriatic arthritis: is the disease impact different? A large matching study at diagnosis and after 1 year of treatment by Annette H M van der Helm-van Mil, Pascal H P de Jong, Sytske Anne Bergstra, Elise van Mulligen, Ilja Tchetverikov, Jolanda J Luime, Marijn Vis, Marc R Kok, Maikel van Oosterhout, Jos H van der Kaap, Selinde V J Snoeck Henkemans, Anne-Fleur van den Biggelaar

“…This difference still existed after 1 year of treatment (3.88 (95% CI 1.90 to 5.86)). PsA-EAC patients had more activity limitations after 1 year of treatment compared with RA-EAC patients (−0.30 (95% CI −0.50 to −0.10)). …”
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Genome-Wide Association Study for Weight-Related Traits in <i>Scylla paramamosain</i> Using Whole-Genome Resequencing by Lin Chen, Yaodong Zhang, Peitan Jia, Siyi Zhou, Qionghui Qin, Weiren Zhang, Kewei Huang, Xiaopeng Wang, Haihui Ye

“…Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) analyses indicated that shared functional terms/pathways among the five traits were mainly related to metabolism, development, and immunity. …”
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CLINICAL AND LABORATORY CHARACTERISTICS OF PATIENTS WITH ISCHEMIC HEART DISEASE RESISTANT TO ACETYLSALICYLIC ACID IN PERIOPERATIVE PERIOD OF CORONARY ARTERY BYPASS GRAFT: RESULTS O... by Yu. I. Grinshtein, A. A. Kosinova, I. Yu. Grinshtein, A. V. Kovalev, V. G. Sukhovol'skiy, A. A. Savchenko

“…Patients (n=60) with stable angina III-IV functional class, undergoing CABG, were included into the study. …”
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Amniotic fluid-derived stem cells: potential factories of natural and mimetic strategies for congenital malformations by Cristiane S. R. Fonteles, Julia Enterria-Rosales, Ying Lin, John W. Steele, Ramiro A. Villarreal-Leal, Jing Xiao, Daniel I. Idowu, Beck Burgelin, Bogdan J. Wlodarczyk, Richard H. Finnell, Bruna Corradetti

“…The possibility to exploit both formulations as mRNA-therapeutics was explored by evaluating cell uptake in two different cell types(fibroblasts, and macrophages) and mRNA functionality overtime in an in vitro experimental setting as well as in an ex vivo, whole embryo culture using pregnant C57BL6 dams. …”
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Biventricular electromechanical dysfunction and molecular remodeling in a rat model of advanced pulmonary arterial hypertension by Francesco Paolo Lo Muzio, Alessia Caputo, Rosario Statello, Mirko Hu, Roberta Maestri, Giovanna Pelà, Aderville Cabassi, Margherita Burattini, Giacomo Rozzi, Silvia Berrettoni, Barbara Montanini, Stefano Rossi, Lorenzo Fassina, Giovanni Battista Luciani, Gianluigi Condorelli, Michele Miragoli

“…Methods In this study, we investigate the late-stage effects of PAH on both electrical and mechanical functions, as well as their coupling, in each ventricle using the monocrotaline-treated rat model. …”
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CONTENT OF URANIUM ISOTOPES IN THE GROUNDWATER SUPPLIES USED FOR POPULATION OF LENINGRAD REGION AND ST-PETERSBURG by M. V. Kaduka, L. N. Basalaeva, T. A. Bekyasheva, S. A. Ivanov, N. V. Salazkina, V. V. Stupina, A. N. Kaduka

“…The study was focused on the water of functioning and exploratory groundwater supplies concerning the safety of water consumption taken into account radiation and chemical index. …”
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