Formulation-Dependent Extrudability of Highly Filled Alginate System for Vaginal Drug Delivery by Arianna Chiappa, Alice Fusari, Marco Uboldi, Fabiana Cavarzan, Paola Petrini, Lucia Zema, Alice Melocchi, Francesco Briatico Vangosa

“…In the absence of solid MTZ, the precursor solutions showed a slightly shear thinning behavior, more accentuated with the increase in ALG concentration. …”
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Development of a clinical decision support tool for Primary care Management of lower Urinary tract Symptoms in men: the PriMUS study by Adrian Edwards, Ridhi Agarwal, Janine Bates, Alison Bray, Sarah Milosevic, Emma Thomas-Jones, Michael Drinnan, Marcus Drake, Peter Michell, Bethan Pell, Haroon Ahmed, Natalie Joseph-Williams, Kerenza Hood, Yemisi Takwoingi, Chris Harding

“…Our findings emphasise the importance of LUTS being managed in primary care where possible, as in addition to cost savings and reduced waiting times, this is a more accessible option for patients, who tend to be more comfortable and confident being treated by familiar clinicians or in more familiar environments. …”
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Effective One-Component Organocatalysts for Eco-Friendly Production of Cyclic Carbonates by Enrique Francés-Poveda, Marta Navarro, Monserrat Beroíza-Duhart, Genesys L. Mahecha, Julio I. Urzúa, María Luisa Valenzuela, Felipe de la Cruz-Martínez, Oscar A. Douglas-Gallardo, Francisca Werlinger, Agustín Lara-Sánchez, Javier Martínez

“…Remarkably, this organocatalyst also facilitated the synthesis of five internal cyclic carbonates and a carvone-derived exo-cyclic carbonate, which was obtained for the first time without the use of a metal catalyst, under more demanding conditions. A mechanistic proposal was developed through a combination of ¹H-NMR studies and density functional theory (DFT) simulations. …”
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Unravelling the prognostic and operative role of intratumoural microbiota in non‐small cell lung cancer: Insights from 16S rRNA and RNA sequencing by Fuling Mao, Zixuan Hu, Ruifeng Shi, Hongbing Zhang, Zihe Zhang, Yongwen Li, Xuanguang Li, Penghu Gao, Jinhui Li, Minghui Liu, Hongyu Liu, Jun Chen

“…Intriguingly, a protective microbial cluster was identified encompassing nine genera associated with delayed disease recurrence, with functional analyses suggested that these microbiota predominantly exerted metabolism‐related functions. …”
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Correspondence of MRI and nTMS With EDSS in Multiple Sclerosis: Longitudinal Follow‐Up Study by Antonia Bralić, Sanda Pavelin, Nikolina Pleić, Joško Šoda, Krešimir Dolić, Anita Markotić, Ana Ćurković Katić, Angela Mastelić, Nikolina Režić Mužinić, Jasna Duranović, Zlatko Kljajić, Ivona Stipica Safić, Zoran Đogaš, Maja Rogić Vidaković

“…EDSS scoring included evaluation of the EDSS general score, EDSS functional pyramidal score, and EDSS functional pyramidal score for each extremity. …”
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Characterization of intrahepatic B cells in acute-on-chronic liver failure by Yudong Zhao, Wei He, Chenchen Wang, Nana Cui, Changjie Yang, Zhengrui You, Bisheng Shi, Lei Xia, Xiaosong Chen

“…Flow cytometry was used to characterize the phenotypic and functional alterations in intrahepatic and circulating B-cell populations from ACLF, cirrhosis, and healthy controls. …”
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Unique target binding by the C-terminal region of FHR1 provides a new perception of aHUS pathology by Luce Perie, Selina Stippa, Christoph Saffer, Christoph Saffer, Andrea Hartmann, Mathias Mörgelin, Svante L. H. Zipfel, Marc Thilo Figge, Marc Thilo Figge, Thorsten Wiech, Christine Skerka, Peter F. Zipfel, Peter F. Zipfel

“…By contrast, SCR5, the most C-terminal domain, was more relevant for C3b/C3d contact. Notably, wild-type FHR1LA selected C3d, while pathogenic aHUS-associated alterations FHR1SV selected C3b. …”
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Alzheimer’s Disease: Understanding Motor Impairments by Jesús Andrade-Guerrero, Humberto Martínez-Orozco, Marcos M. Villegas-Rojas, Alberto Santiago-Balmaseda, Karen M. Delgado-Minjares, Isaac Pérez-Segura, Mauricio T. Baéz-Cortés, Miguel A. Del Toro-Colin, Magdalena Guerra-Crespo, Oscar Arias-Carrión, Sofía Diaz-Cintra, Luis O. Soto-Rojas

“…Addressing motor symptoms alongside cognitive decline may enhance patient functionality, improve quality of life, and support more comprehensive disease management strategies.…”
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The multifaceted role of the inferior colliculus in sensory prediction, reward processing, and decision-making by Xinyu Du, Haoxuan Xu, Peirun Song, Yuying Zhai, Hangting Ye, Xuehui Bao, Qianyue Huang, Hisashi Tanigawa, Zhiyi Tu, Pei Chen, Xuan Zhao, Josef P Rauschecker, Xiongjie Yu

“…This research highlights a more complex role for the IC than traditionally understood, showcasing its integral role in cognitive and sensory processing and emphasizing its importance in integrated brain functions.…”
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Locking compression plate as a sequential external fixator following the distraction phase for the treatment of tibial bone defects caused by fracture-related infection: experience... by Xiriaili Kadier, Kai Liu, Aierbanjiang Shali, Yimurang Hamiti, Sulong Wang, Xin Yang, Alimu Keremu, Aihemaitijiang Yusufu

“…At the final follow-up, bone and functional outcomes were evaluated using the ASAMI criteria. …”
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Effectiveness of Digital Health Interventions for Chronic Obstructive Pulmonary Disease: Systematic Review and Meta-Analysis by Miaoqing Zhuang, Intan Idiana Hassan, Wan Muhamad Amir W Ahmad, Azidah Abdul Kadir, Xiaodong Liu, Furong Li, Yinuo Gao, Yang Guan, Shuting Song

“…Outcomes included quality of life, self-efficacy, functional status, and health care use. …”
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Evaluating Degenerative Lumbar Disease with Markerless 3D Motion Capture: Reliability and Validity in Sit-to-Stand Test by Yi-Ting Huang, Szu-Hua Chen, Chao-Ying Chen, Shiu-Min Wang, Pei-Yuan Wu, Dar-Ming Lai, Wei-Li Hsu

“…Markerless motion capture offers a portable alternative, yet its functional assessment applications in DLD remain underexplored. …”
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Programas de intervención física en mujeres mayores a través del método Pilates: Una revisión sistemática (Physical intervention programs in older women trough the Pilates method:... by Virginia Tejada Medina, Carlos Díaz Caro, Cristian González García, Pedro Jesús Ruiz Montero

“…The proportion of people over 60 has increased more rapidly than any other age group. This fact directly influences health and functional capacity, = gender being a transversal determinant of active aging that reflects enormous disadvantages in older women. …”
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U.S. UNIVERSITY WEBSITES AS SPECIFIC MULTIMODAL TEXTS by Svitlana V. Fedorenko, Kateryna B. Sheremeta

“…It also employed the system functional (drawing on the provisions of linguistic metafunctions, and focusing on the categories of the grammar of visual design) and the socio-semiotic (grounding on the interrelationship of modes, their compatibility and social needs for which they serve, making meanings) approaches. …”
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A Longitudinal Study of the Bidirectional Temporal Dynamics Between Body Mass Index and Biological Aging by Peggy Ler, Jonathan K. L. Mak, Chandra A. Reynolds, Alexander Ploner, Nancy L. Pedersen, Juulia Jylhävä, Anna K. Dahl Aslan, Deborah Finkel, Ida K. Karlsson

“…FI measured physiological aging, while FAI assessed functional aging through a composite score of functional abilities. …”
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Effects of intravenous immunoglobulin on the negatively transformed subpopulations of neutrophilic granulocytes in newborns with congenital pneumonia and neonatal sepsis by I. V. Nesterova, S. V. Kovaleva, G. A. Chudilova, L. V. Lomtatidze, T. V. Smerchinskaya, V. N. Chapurina

“…The aim of our study was to assess the effects of intravenous immunoglobulin (IVIG) injections on the negatively transformed subpopulations of neutrophilic granulocytes (NG) СD64-CD16+СD32+СD11b+, СD64+CD16+СD32+СD11b+ and evaluation of their functional activity in newborns with CP and NS. We have observed 38 full-term newborn patients. …”
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Knowledge graph and bibliometric analysis of inflammatory indicators in ovarian cancer by Liyan Zhang, Linlin Guo, Haiyan Wang, Huan Yang, Jiarui Dong

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Comparison of therapeutic effects of 0.05% Cyclosporine A versus 0.1% Fluorometholone in Chinese patients with mild dry eye unresponsive to artificial tears: a randomized control s... by Huijuan Gao, Lu Zhao, Aoxue Du, Xia Zhang, Mengdi Chai, Lin Liu, Emmanuel Eric Pazo, Ruihua Wei

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Gradient hydrogels based on photo-initiated polymerization-induced self-assembly by Yingchu Zhou, Ziqi Liu, Yi Zeng, Li Luo, Jie Chen, Diyuan Zheng, Zhao Wu, Chao Lang

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Calcium Release-Activated Calcium Modulator ORAI1-Sensitive Serine Dehydratase Regulates Fatty Acid-Induced CD4⁺ Th17/Treg Imbalance in Dairy Cows by Bingbing Zhang, Jingjing Wang, Ming Li, Jianan Wen, Juan J. Loor, Shuang Wang, Ziwei Ji, Xinquan Lv, Guihua Wang, Cheng Xia, Wei Yang, Chuang Xu

“…High concentrations of free fatty acids (FFAs) caused by negative energy balance render the cow more prone to inflammatory diseases in part due to an imbalance in the types of immune cells and their specific functions. …”
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