Cardiomyocyte specific CD38 deletion protects heart from acute myocardial infarction by activating Sirt3 signaling pathway by Ke Wen, Ya-Ting Zhang, Qi-Hang Zhao, Qian Li, Jia-Le Zhao, Qi Ding, Yun-Fei Xiao, Xiao-Hui Guan, Mei-Xiu Jiang, Yi-Song Qian, Xiao-Li Tian, Ling-Fang Wang, Ke-Yu Deng, Hong-Bo Xin

“…Consistently, knockdown of CD38 protected hypoxia-induced apoptosis in cardiomyocytes by increasing the ratio of Bcl2/Bax expression and decreasing cleaved caspase-3. More importantly, 3-TYP, a Sirt3 inhibitor, significantly increased hypoxia-induced apoptosis in CD38-deficient primary cardiomyocytes. …”
Get full text

From Chains to Arrays: Substrate-Mediated Self-Assembly of Diboron Molecules by Xiaoyu Hao, Huixia Yang, Mengmeng Niu, Tingting Wang, Hongyan Ji, Iulia Emilia Brumboiu, Cesare Grazioli, Ambra Guarnaccio, Albano Cossaro, Yan Li, Jingsi Qiao, Quanzhen Zhang, Liwei Liu, Teng Zhang, Yeliang Wang

“…Notably, the B-B bond in the molecular arrays on BLG is distinctly pronounced, reflecting a more refined molecular resolution with distinct electronic states than that on Au(111). …”
Get full text

Adverse Events and Immune Response in Psoriasis Patients Receiving Interleukin-17 Inhibitors by Christopher Willy Schwarz, Charlotte Näslund-Koch, Claus Zachariae, Jakob Benedict Seidelin, Susanne Dam Nielsen, Sisse Rye Ostrowski, Karen Marie Thyssen Astvad, Inger Brock, Lars Iversen, Mads Kirchheiner Rasmussen, Nikolai Loft, Lone Skov

“…This study aimed to identify predictive markers for these adverse events and to describe the functional immune response in patients treated with interleukin-17 inhibitors using a whole-blood stimulation system (TruCulture®). …”
Get full text

Increased Chemokine Production is a Hallmark of Rhesus Macaque Natural Killer Cells Mediating Robust Anti-HIV Envelope-Specific Antibody-Dependent Cell-Mediated Cytotoxicity by Junsuke Nohara, Tyler Evangelous, Madison Berry, Whitney Beck, Sarah Mudrak, Shalini Jha, R. Keith Reeves, Kevin J. Wiehe, Justin Pollara, Georgia Tomaras, Todd Bradley, Guido Ferrari

“…Currently, the heterogeneities of the functional subset of rhesus macaque natural killer (RMNK) cells are under-characterized.  …”
Get full text

Utilization of Response Surface Methodology in Optimization of Polysaccharides Extraction from Vietnamese Red Ganoderma lucidum by Ultrasound-Assisted Enzymatic Method and Examinat... by Dat Tran Do, Dang Hoang Lam, Tai Nguyen, Tran Thi Phuong Mai, Le Thao My Phan, Hoai Thanh Vuong, Duc Viet Nguyen, Ngo Thi Thuy Linh, Minh Nam Hoang, Thanh Phong Mai, Huu Hieu Nguyen

“…The Fourier-transform infrared spectroscopy was also used to identify the functional groups in the extracts. The molecular weights of polysaccharides were determined by gel permeation chromatography. …”
Get full text

Inactivation of antibiotic resistant bacteria by nitrogen-doped carbon quantum dots through spontaneous generation of intracellular and extracellular reactive oxygen species by Weibo Xia, Zixia Wu, Bingying Hou, Zhang Cheng, Dechuang Bi, Luya Chen, Wei Chen, Heyang Yuan, Leo H. Koole, Lei Qi

“…In in vivo studies, the N-CQDs were more efficient in treating drug-resistant bacterial keratitis and reducing corneal damage compared to the common antibiotic levofloxacin. …”
Get full text

Deciphering the role of traditional flipping crafts in medium-temperature Daqu fermentation: Microbial succession and metabolic phenotypes by Zhang Wen, Yu-Hua Wei, Da-Yong Han, Liang Song, Hai-Yan Zhu, Liang-Chen Guo, Shen-Xi Chen, Bin Lin, Chao-Jiu He, Zheng-Xiang Guo, Pei-Jie Han, Feng-Yan Bai

“…Co-occurrence network analysis revealed that the microbial community in FD was simpler yet more stable compared to that in NFD. Microbial succession in MTD was primarily driven by interspecies interactions and environmental factors. …”
Get full text

Factors affecting the design of the management dashboard framework with an emphasis on the components of human resources productivity by Hassan Barmaki, Farshad Faezy Razi, Ehtesham Rashidi

“…It collects information gathered from all departments of the organization, which contains various sources related to various business functions. This information is combined and replicated by providing a user interface in the form of graphs, reports, visual indicators and alerting mechanisms. …”
Get full text

Special Issue on Contemporary Research Studies in Operations Research, Business Analytics, and Business Intelligence by Viswanath Kumar Ganesan, S. Vinodh, Malolan Sundararaman, M. Vimala Rani, M. Mathirajan

“…These involve utilizing information technology and analytics more effectively, innovating manufacturing and service support systems, and employing novel problem-solving methods. …”
Get full text

Downscaling of Soil Moisture Map using Sentinel Radar Satellite Images and Distribution Analysis in the West of Iran by Seyed Hossein Mirmosavi, kohzad Raispour, Muhammad Kamangar

“…In this study, soil moisture microscaling based on the work of Pasoli (2015) and Jennifer (2016) with the functions available in the Google Earth Engine system was obtained. …”
Get full text

Breakfast skipping and depressive symptoms in an epidemiological youth sample in Hong Kong: the mediating role of reduced attentional control by Stephanie Ming Yin Wong, Olivia Choi, Yi Nam Suen, Christy Lai Ming Hui, Edwin Ho Ming Lee, Sherry Kit Wa Chan, Sherry Kit Wa Chan, Eric Yu Hai Chen, Eric Yu Hai Chen, Eric Yu Hai Chen

“…Participants were asked about their general breakfast consumption habits, impulsivity (overall and its subdomains, using the Barratt Impulsiveness Scale–11), depressive symptoms (Patient Health Questionnaire–9), anxiety symptoms (Generalized Anxiety Disorder Scale–7), and functioning (reduced and lost productivity due to mental health problems, and the observer-rated Social and Occupational Functioning Assessment Scale). …”
Get full text

Mitochondria dysfunction, a potential cytoprotection target against ischemia-reperfusion injury in a mouse stroke model by Elodie Ong, Paul Clottes, Christelle Leon, Hala Guedouari, Noelle Gallo-Bona, Megane Lo Grasso, Lucas Motter, Radu Bolbos, Michel Ovize, Norbert Nighogossian, Marlene Wiart, Melanie Paillard

“…More than 50 ​% of patients undergoing mechanical thrombectomy (MT) for ischemic stroke have a poor functional outcome despite timely and successful angiographic reperfusion, highlighting the need for adjunctive treatments to reperfusion therapy. …”
Get full text

Daily carbon dioxide fluxes in Arctic tundra and forest-tundra ecosystems in response to temperature and precipitation extremes by Elizaveta Gorbarenko, Daria Gushchina, Maria Tarasova, Irina Zheleznova, Ekaterina Emelianova, Ravil Gibadullin, Alexander Osipov, Alexander Olchev

“…The development and functioning of landscapes in different regions of the world, especially at polar latitudes, may be significantly affected by the increased frequency of extreme weather events associated with modern climate change. …”
Get full text

Neurovascular coupling of inhibitory control in late-onset depression: a simultaneous EEG-fMRI study by Elena Bondi, Alessandro Pigoni, Adele Ferro, Maria Pia Marra, Guido Nosari, Giandomenico Schiena, Fabio M. Triulzi, Anna M. Bianchi, Paolo Brambilla, Eleonora Maggioni

“…Depression is a leading cause of disability that exerts an impact on neurocognitive functions. Individuals with major depressive disorder (MDD) have shown alterations of processes underlying response inhibition, which is the cognitive process that permits the suppression of habitual or natural behavioural responses to stimuli to select a more appropriate response that is coherent with the goal; these alterations have been correlated with cognitive deficits, especially in older adults. …”
Get full text

Protein Kinase-Major Sperm Protein (PK-MSP) Genes Mediate Recognition of the Fungal Necrotrophic Effector SnTox3 to Cause Septoria nodorum Blotch in Wheat by Zengcui Zhang, Katherine L. D. Running, Sudeshi Seneviratne, Amanda R. Peters Haugrud, Agnes Szabo-Hever, Gurminder Singh, Kateřina Holušová, István Molnár, Jaroslav Doležel, Timothy L. Friesen, Justin D. Faris

“…DNA sequence divergence of Snn3-B1 and Snn3-B2 and differences in transcriptional expression patterns and three-dimensional protein conformation were associated with a more severe programmed cell death response conferred by Snn3-B2 compared with Snn3-B1. …”
Get full text

Bridging the 3D geometrical organisation of white matter pathways across anatomical length scales and species by Hans Martin Kjer, Mariam Andersson, Yi He, Alexandra Pacureanu, Alessandro Daducci, Marco Pizzolato, Tim Salditt, Anna-Lena Robisch, Marina Eckermann, Mareike Töpperwien, Anders Bjorholm Dahl, Maria Louise Elkjær, Zsolt Illes, Maurice Ptito, Vedrana Andersen Dahl, Tim B Dyrby

Get full text

Stratification system with dual human endogenous retroviruses for predicting immunotherapy efficacy in metastatic clear-cell renal cell carcinoma by Li Xu, Stephane Oudard, Catherine Sautes-Fridman, Xiaoping Su, Gabriel G. Malouf, Virginie Verkarre, Salma Kotti, Fangrong Yan, Yann-Alexandre Vano, Wolf Herve Fridman, Cheng-Ming Sun, Xiaofan Lu, Wenxuan Cheng

Get full text

Revealing electron transport connectivity as an important factor influencing stability of organic solar cells by Haixia Hu, Rui Zhang, Dongcheng Jiang, Xinyu Mu, Jicheng Yi, Han Yu, Lik-Kuen Ma, Bin Li, Lingxin Cao, Mengzhen Sha, Jiangkai Sun, Ruohua Gui, Wei Liu, Shijie Liang, Longlong Li, Shufen Huang, Jianyu Yuan, Chengwang Niu, Cunquan Qu, Jun Yuan, Rongkun Zhou, Chen Zhang, Lin Lu, Xiaoyan Du, Kun Gao, Weiwei Li, Shu Kong So, Yingping Zou, Yanming Sun, Xiaotao Hao, Feng Gao, He Yan, Hang Yin

Get full text

Significantly enhanced electrocaloric effect by composition modulation in lead-free BaTiO3-based ceramics by Yingzhi Meng, Silin Tang, Zhaojie Wang, Xiang Niu, Hongfang Zhang, Dingyuan Wang, Yisong Bai, Biaolin Peng, Sheng-Guo Lu, Qingqing Ke, Laijun Liu

Get full text

Prevalence, spectrum, and the relations between short-term and long-term post-acute sequelae of COVID-19 in children by Elena R. Meskina, Marima K. Khadisova, Anna Y. Ushakova, Elena E. Tselipanova, Lidiya A. Galkina

“…It is important to study the association between PCC, previous functional disorders, and any events in the post-acute period of COVID-19 to estimate the true burden of PCC in children. …”
Get full text