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32501
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32502
SaGP: identifying plant saline-alkali tolerance genes based on machine learning techniques
Published 2025-07-01“…Wet experiments are the main methods to uncover genes with target functions but are expensive and time-consuming. Machine learning, in contrast, can accelerate the gene discovery process by learning from accumulated data, making it more efficient and cost-effective. …”
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32503
Regulatory mechanisms of the Hippo/YAP axis by G-protein coupled estrogen receptor in gastric signet-ring cell carcinoma
Published 2025-09-01“…In this study, we integrated in vitro cytological functional assays with GSRC cell lines and in vivo xenograft nude mice models to elucidate the functional implications of GPER in GSRC. …”
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32504
Robotic Rehabilitation Devices in the Philippines: A Review of Recent Advancements
Published 2025-04-01“…Results: Findings indicate that the Philippines is becoming more receptive to rehabilitation robotics, as evidenced by increasing recognition of its relevance and the procurement of foreign-developed technologies. …”
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32505
SGK1 drives hippocampal demyelination and diabetes-associated cognitive dysfunction in mice
Published 2025-02-01“…Here, we performed single-nucleus RNA sequencing (snRNA-seq) to demonstrate unique cellular and molecular patterns of the hippocampus from a mouse model of diabetes. More in-depth analysis of oligodendrocytes (OLs) distinguished five subclusters, indicating different functional states of OLs and transcriptional changes in each subcluster. …”
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32506
Deletion of the African Swine Fever Virus Gen <i>I196L</i> in the Georgia2010 Isolate Genome Does Not Affect Virus Replication or Virulence in Domestic Pigs
Published 2025-04-01“…The ASFV genome encodes for more than 160 proteins; however, the functions of most of them are still in the process of being characterized. …”
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32507
Modification of Spanish Mackerel (<i>Scomberomorus niphonius</i>) Surimi Gels by Three Anionic Polysaccharides
Published 2025-07-01“…This study will demonstrate the effectiveness of KC, IC, and GG in improving the texture and functionality as well as expanding the application of surimi products.…”
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32508
Thio-ProTide strategy: A novel H2S donor–drug conjugate (DDC) alleviates hepatic injury via innate lysosomal targeting
Published 2024-12-01“…These findings provided a novel pattern for the design of optimally therapeutic H2S DDC and organelle-targeting functional molecules.…”
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32509
Re-use of Building Products in the Netherlands
Published 2019-01-01“… Over the years, the consumption of materials for construction exceeded more than half of the total materials consumed in the Netherlands, and construction waste exceeded the volume of solid waste produced by households. …”
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32510
Impact on Outcome of Different Mechanisms, Baseline Degree and Changes of Mitral Regurgitation in Patients With Aortic Stenosis Who Underwent Transcatheter Aortic Valve Replacement
Published 2024-07-01“…The study population was divided into 4 groups according to MR mechanism: Group I: fibro‐calcific leaflet degeneration; Group II: prolapse/flail; Group III: ventricular secondary MR (functional MR); and Group IV: atrial functional MR. …”
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32511
Mixed Systems of Quaternary Ammonium Foam Drainage Agent with Carbon Quantum Dots and Silica Nanoparticles for Improved Gas Field Performance
Published 2024-10-01“…Carbon quantum dots were then prepared and functionalized with dodecylamine. Finally, carbon quantum dots were incorporated into the mesopores of silica nanoparticles to enhance stability. …”
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32512
Cathepsin G promotes arteriovenous fistula maturation by positively regulating the MMP2/MMP9 pathway
Published 2024-12-01“…However, the low maturation rate of AVF severely affects its use in patients. A more comprehensive understanding and study of the mechanisms of AVF maturation is urgently needed.Methods and results In this study, we downloaded the publicly available datasets (GSE119296 and GSE220796) from the Gene Expression Omnibus (GEO) and merged them for subsequent analysis. …”
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32513
Acupuncture promotes muscle cells ATP metabolism in ST36 acupoint local exerting effect by activating TRPV1/CaMKII/AMPK/PGC1α signaling pathway
Published 2025-07-01“…Further analysis revealed that this analgesic effect was closely related to the up-regulation of local TRPV1 expression at ST36, and its deletion or functional inhibition would significantly weaken the analgesic effect of acupuncture. …”
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32514
ROC analysis data and predictors of rehabilitation effectiveness in patients with type 2 diabetes mellitus
Published 2025-05-01“…Effective rehabilitation for such patients contributes to the improvement of their functional status, reduces the risk of complications, and enhances the overall prognosis. …”
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32515
Comparison of the inflammatory biomarkers IL- 6, TNF-α, and CRP to predict the effect of nutritional therapy on mortality in medical patients at risk of malnutrition
Published 2025-04-01“…Methods This is a secondary analysis of the Swiss-wide, multicenter, randomized controlled Effect of early nutritional therapy on Frailty, Functional Outcomes, and Recovery of malnourished medical inpatients Trial (EFFORT) trial comparing individualized nutritional support with usual care nutrition in medical inpatients. …”
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32516
The Analysis and the Optimizat ion of an Auto nomous Mobile Plat form Equipped with a Manipulator Arm for Sample Retrieval in Rough Terrain
Published 2025-06-01“…It provides operators with a visual perspective that surpasses mere data points, enabling more informed decision-making and better situational awareness. …”
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32517
Two-stage strategic optimal planning of distributed generators and energy storage systems considering demand response program and network reconfiguration
Published 2024-10-01“…Subsequently, the backward reduction algorithm (BRA) is employed to streamline the resulting scenarios into a more feasible and representative subset, therefore mitigating excessive computational effort. …”
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32518
Prognostic importance of the Controlling Nutritional Status (CONUT) score in patients undergoing cardiac resynchronisation therapy
Published 2021-12-01“…The primary endpoint was all-cause mortality.Results The moderate or severe malnutrition group had a lower body mass index, more advanced New York Heart Association functional class, higher Clinical Frailty Scale score, lower levels of haemoglobin and higher levels of N-terminal probrain natriuretic peptide (all p<0.05). …”
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32519
AlphaMissense Predictions and ClinVar Annotations: A Deep Learning Approach to Uveal Melanoma
Published 2025-05-01“…We explore the use of a novel deep learning tool to assess the functional impact of genetic mutations in UM. Design: A cross-sectional bioinformatics exploratory data analysis of genetic mutations from UM cases. …”
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32520
Health status biomarkers and hemato-biochemical indices in Nile tilápia
Published 2024-12-01“…For all hematological parameters we found a difference between the lack and presence of the anticoagulants, being the lack and heparin the conditions that presented more stability of the cell numbers along the time. …”
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