State-of-the-art: Insights from the Ross RegistryCentral Message by Buntaro Fujita, MD, Anas Aboud, MD, Hans-Hinrich Sievers, MD, Stephan Ensminger, MD, DPhil

“…The Ross procedure uses the autologous pulmonary valve as an aortic valve substitute and aims to improve valve durability while avoiding anticoagulation and therefore achieve a sustained long-term result with regard to survival, valve functionality, and quality of life. However, this procedure is technically demanding and only performed at a low frequency. …”
Get full text

Assessment of Quality of Life and Stomatognathic Dysfunction in Patients with Maxillofacial Defects Before Orthognathic Surgery by Magdalena Gębska, Zuzanna Sobczyk, Łukasz Pałka, Dorota Margula-Jaśkowska, Konrad Olszewski, Łukasz Kołodziej, Katarzyna Weber-Nowakowska, Robert Kowalczyk, Piotr Seweryn, Bartosz Dalewski

“…Results: Significant differences were observed between the study groups regarding all quality-of-life indicators for orthodontic and orthognathic patients. Patients in the SG more frequently reported difficulties in the specified stomatognathic system functions compared to those in the CG. …”
Get full text

Alzheimer’s disease diagnosis using rhythmic power changes and phase differences: a low-density EEG study by Juan Wang, Juan Wang, Jiamei Zhao, Xiaoling Chen, Xiaoling Chen, Bowen Yin, Xiaoli Li, Xiaoli Li, Ping Xie, Ping Xie

“…Notably, decreased theta band functional connectivity within the fronto-central lobe and increased frequency coupling in frontal region were found in AD group from EC to EO. …”
Get full text

Investigating the temperature-dependent selectivity of CO2 reduction on Ru-cluster catalysts supported by MXene by Yueying Liu, Xiang Li, Yi Li, Rong Wei, Hongwei Tan, Xichen Li, Guangju Chen

“…This work also highlights that the impact of temperature on the catalytic activity and selectivity of catalysts comprising metal clusters should be subjected to more rigorous investigation.…”
Get full text

DeSa COVID-19: Deep salient COVID-19 image-based quality assessment by Risnandar

“…The DeSa COVID-19 more superior the recommended DCNN and also the other recent full-reference medical image quality assessment methods.…”
Get full text

Beyond inflammation: the molecular basis of bone remodeling in axial spondyloarthritis and psoriatic arthritis by Giuseppe Lopalco, Andrea Cito, Florenzo Iannone, Torsten Diekhoff, Denis Poddubnyy, Denis Poddubnyy, Fabian Proft

“…It aims to enhance the understanding of these processes to support the development of more precise and effective therapeutic approaches tailored to axSpA and PsA.…”
Get full text

Temporal profiling of M‐TEER‐related complications by Jafer Haschemi, Hanna Schrameck, Jean Marc Haurand, Daniel Oehler, Maximilian Spieker, Fabian Voss, Malte Kelm, Amin Polzin, Patrick Horn

“…Results The median age was 80 (74, 84) years, and the EuroScore II was high (6.5 [4.0, 12.0] %). Functional mitral regurgitation (MR) was more common than degenerative or mixed MR (69% vs. 20%. respectively; 11%). …”
Get full text

Potential effect of Irisin on sarcopenia: a systematic review by Yixiao Chen, Min Qian, Feng Gao, Guoqing Li, Kangzu Peng, Qingnan Sun, Yifei Sun, Gang Liu, Yufeng Ge, Minghui Yang, Xinbao Wu

“…This condition significantly increases the risk of debilitating consequences including functional impairment, diminished life quality, and increased mortality. …”
Get full text

Physical symptoms distress and demoralization among haemodialysis patients; the mediating effect of spirituality and self-compassion. A cross-sectional questionnaire survey by Chia-Hui Lin, Yi-Chien Chiang, Wen-Yi Li, Tsung-Lan Chu, Ya-Chu Hsiao

“…Methods: Self-report questionnaires were the Physical Symptom Distress Scale, Demoralization Scale, Functional Assessment of Chronic Illness Therapy-Spiritual Well-Being Scale-12, and Self-Compassion Scale. …”
Get full text

ROC analysis determines optimal cutoff and doubtable interval of the Bath ankylosing spondylitis metrology index in a multicenter case control study by Genggeng Guo, Juanjuan He, Jianwen Liu, Xiaoye Yan, Meng Zhou, Chenmin Wu, Diantian Lin, Zhihan Chen, Qing Yan, Fei Gao, Zugang Xie, Feng Huang, Shengli Zhang

“…Abstract In clinical practice, the Bath Ankylosing Spondylitis Metrology Index (BASMI) score of healthy individuals is more than zero. However, the lower limit of the BASMI score range for patients with ankylosing spondylitis (AS) is 0, which is inconsistent with that observed in actual clinical settings. …”
Get full text

Computed tomography-derived quantitative imaging biomarkers enable the prediction of disease manifestations and survival in patients with systemic sclerosis by Gabriela Riemekasten, Felix Nensa, Hanna Grasshoff, René Hosch, Malte Maria Sieren, Lennart Berkel, Jörg Barkhausen, Roman Kloeckner, Franz Wegner

“…These parameters were analysed with regard to various clinical, laboratory, functional parameters and survival. Phenotypes were identified performing K-means cluster analysis. …”
Get full text

Available Nitrogen as the Determinant of Variability in Soil Microbial Communities Throughout <i>Lycium chinense</i> Growth Zones in the Qaidam Basin, Qinghai, China by Qianqian Su, Jie Li, Jingui Wang, Gang Li, Yang Sun, Xiaoqin Liu, Lan Luo, Xinrui Wang, Guilong Zhang

“…Understanding the compositional and functional dynamics of soil microbial communities is crucial for optimizing soil fertility and promoting agricultural sustainability. …”
Get full text

Immune-related gene SOX10 affects ferroptosis in pancreatic cancer and facilitates tumor progression by targeting CMTM7-mediated Wnt/β-catenin signaling pathway by Guixing Jiang, Bicheng Wu, Kaikai Wang, Xiaofan Pu, Senhao Zhou, Xin Zhong, Xiaolong Liu, Suihan Wang, Tianyu Lin

“…The expression of SOX10 and CMTM7 was analyzed using quantitative real-time polymerase chain reaction and western blot. To assess cell functions, cell counting kit-8, flow cytometry, scratch test, and Transwell assays were performed. …”
Get full text

Oncologic outcomes with and without amniotic membranes in robotic-assisted radical prostatectomy: A propensity score matched analysis by Jonathan Noël, Daniel Stirt, Marcio Covas Moschovas, Sunil Reddy, Abdel Rahman Jaber, Marco Sandri, Seetharam Bhat, Travis Rogers, Subuhee Ahmed, Anya Mascarenhas, Ela Patel, Vipul Patel

“…Cumulative incidence functions for BCR did not show a difference between the groups (p=0.3). …”
Get full text

Enhancing the selectivity and conditional sensitivity of an antimicrobial peptide through cleavage simulations and homoarginine incorporation to combat drug-resistant bacteria by Keyi Yao, Jiachen Liu, Ruize Sun, Yun Wang, Yangyang Jiang, Tao Wang, Xiaoling Chen, Chengbang Ma, Tianbao Chen, Chris Shaw, Mei Zhou, Lei Wang

“…This approach may help address some key challenges in peptide-drug development, paving the way for more effective antimicrobial therapies.…”
Get full text

Injection of human umbilical cord mesenchymal stem cells exosomes for the treatment of knee osteoarthritis: from preclinical to clinical research by Yuzhong Wang, Yajie Kong, Jiejie Du, Lifei Qi, Meiling Liu, Siyi Xie, Jianghui Hao, Ming Li, Shuxing Cao, Huixian Cui, Aijing Liu, Jun Ma, Yongzhou Song

“…Abstract Background Background: Exosomes (Exos) derived from mesenchymal stem cells (MSCs) share similar biological functions with MSCs but are more stable under various pathophysiological conditions, with a lower risk of immune rejection. …”
Get full text

Disentangling the gut microbiota of Aldabra giant tortoises of different ages and environments by Douaa Zakaria, Camillo Sandri, Monica Modesto, Caterina Spiezio, Donatella Scarafile, Allen Cedras, Luigimaria Borruso, Paolo Manghi, Paolo Trevisi, Nicola Segata, Paola Mattarelli, Masanori Arita

“…Background The gut microbiota plays a pivotal role in regulating the physiological functions of its host, including immunity, metabolism, and digestion. …”
Get full text

A brief exploration of the physical properties of single living cells under dynamic loading conditions by Dasen Xu, Chongyu Zhang, Ruining Peng, Ruining Peng, Ru Zhang, Haoyu Chen, Yulong Li, Yulong Li, Hui Yang, Hui Yang

“…Introduction:Single living cells exhibit both active biological functions and material-like mechanical behaviors. While extensive research has focused on static or quasi-static loading, the purely mechanical properties under high-rate impact remain underexplored. …”
Get full text

Heterogeneous expression of long noncoding RNA RP11-109D20.2: Insights into regulatory gene expression roles in colon cancer by Sara Chitgaran, Reihaneh Alsadat Mahmoudian, Seyed Saeed Khatami, Fatemeh Nasrabadi, Ehsan Soltani, Amirnader Emami Razavi, Fatemeh Kamali, Ahmad Reza Bahrami, Maryam Moghaddam Matin, Moein Farshchian

“…Objective(s): Colorectal cancer is one of the deadliest cancers worldwide, which can be prevented and even cured by early diagnosis and more efficient treatment modalities. Comprehensive transcriptional analysis has highlighted the importance of lncRNAs in CRC tumorigenesis. …”
Get full text

scRNA-Seq reveals age-dependent microglial evolution as a determinant of immune response following spinal cord injury by Lufei Shao, Yueliang Chang, Jinfang Liu, Leilei Lin, Long Chang, Jialin Zhang, Zhibin Lan, Honglai Zhang, Xiaolei Chen

“…Spinal cord injury (SCI) is a debilitating condition of the central nervous system (CNS) that leads to severe impairments in sensory and motor functions. Previous studies have pointed out that patient age is a critical factor influencing SCI prognosis. …”
Get full text