Therapeutic alliance impact on analgesic outcomes in a real-world clinical setting: An observational study by Barrachina Jordi, Margarit César, Andreu Blanca, Zandonai Thomas, Ballester Pura, Muriel Javier, Cutillas Esperanza, Peiró Ana M.

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New Data on Migration Time, Breeding Phenology, and Breeding Success of European Turtle Doves in Their Highest Breeding Habitats in North Africa by Ismail Mansouri, Driss Ousaaid, Wafae Squalli, Abdelbari El Agy, Abderahim EL-Hassani, Mohamed Mounir, Lahsen Elghadraoui, Mohamed Dakki

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Transcriptomic Analysis of Macrophages Infected with <i>Mycobacterium smegmatis</i> by Hong Sun, Yue Hou, Wenzhao Xu, Wenjing Wang, Na Tian, Dingyi Liu, Zhaogang Sun

“…Transcriptomics is an emerging research tool in recent years, which can deeply explore the relevant molecules inside a cell and explore the possible regulatory mechanisms more comprehensively. In this study, we first constructed an in vitro model of <i>M. smeg</i>-infected macrophages, collected RNA extracted from the infected cells, performed transcriptome sequencing using the Illunima platform, and verified the expression levels of the main markers related to phenotypic or functional changes in macrophages by qPCR and ELISA. …”
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Genetically Engineered IL12/CSF1R‐Macrophage Membrane‐Liposome Hybrid Nanovesicles for NIR‐II Fluorescence Imaging‐Guided and Membrane‐Targeted Mild Photothermal‐Immunotherapy of G... by Pengfei Chen, Yue Liu, Haiyan Huang, Menglong Li, Hui Xie, Shubham Roy, Jingsi Gu, Jian Jin, Kai Deng, Lixin Du, Bing Guo

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Cembranoid Diterpenes from South China Sea Soft Coral <i>Sarcophyton crassocaule</i> by Hanyang Peng, Yanbo Zeng, Rui Zhang, Li Yang, Fei Wu, Cuijuan Gai, Jingzhe Yuan, Wenjun Chang, Haofu Dai, Xiachang Wang

“…Overall, our research results have enriched the library of secondary metabolites from soft corals, providing more molecular entities for subsequent research and development of related compounds.…”
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Mental health care cascade performance and associated factors: longitudinal analyses of routine Ministry of Health services in Mozambique by Kenneth Sherr, Bradley H Wagenaar, Monisha Sharma, Bryan J Weiner, Morgan Turner, Alberto Muanido, Vasco Cumbe, João Nhalimue Jala, Ernesto Eusébio Armando, Eduarte Mambuque, Flávia Faduque, Ernesto Rodrigo Xerinda, Brian P Flaherty

“…Compared with single persons, those in a domestic union had 3.3 times higher odds of demonstrating functional improvement or low functional impairment (95% CI: 1.8, 6.1). …”
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Heterogeneity of CD8αα intraepithelial lymphocytes is transcriptionally conserved between TCRαβ and TCRγδ cell lineages by Kaito A. Hioki, Kaito A. Hioki, Kaito A. Hioki, Xueting Liang, Xueting Liang, Adam C. Lynch, Adam C. Lynch, Adam C. Lynch, Ravi Ranjan, Elena L. Pobezinskaya, Leonid A. Pobezinsky, Leonid A. Pobezinsky

“…Using CD160 and CD122 as markers of memory-like and effector-like cells, respectively, we found that while effector-like cells dominated the small intestine, memory-like IELs were more prevalent in the large intestine, suggesting a functional specialization of immune responses along the gut. …”
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Gut Microbiota and Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD): Emerging Pathogenic Mechanisms and Therapeutic Implications by Farah Abdelhameed, Attia Mustafa, Chris Kite, Lukasz Lagojda, Alexander Dallaway, Nwe Ni Than, Eva Kassi, Ioannis Kyrou, Harpal S. Randeva

“…Characterized by excessive hepatic fat accumulation, this disease encompasses a spectrum from simple steatosis to more severe forms, including steatohepatitis, fibrosis, and cirrhosis. …”
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Impact of interstitial elements on the stacking fault energy of an equiatomic CoCrNi medium entropy alloy: theory and experiments by Igor Moravcik, Martin Zelený, Antonin Dlouhy, Hynek Hadraba, Larissa Moravcikova-Gouvea, Pavel Papež, Ondřej Fikar, Ivo Dlouhy, Dierk Raabe, Zhiming Li

“…Both N and C in solid solution increase the SFE of the face-centered cubic (FCC) alloy matrix at room temperature, with the former having a more significant effect by 240% for 0.5 at % N. Total energy calculations based on density functional theory (DFT) as well as thermodynamic modeling of the Gibbs free energy with the CALPHAD (CALculation of PHAse Diagrams) method reveal a stabilizing effect of N and C interstitials on the FCC lattice with respect to the hexagonal close-packed (HCP) CoCrNi-X (X: N, C) lattice. …”
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Gut microbiota as a biomarker and modulator of anti-tumor immunotherapy outcomes by Jiexi Yan, Lu Yang, Qingmiao Ren, Chan Zhu, Haiyun Du, Zhouyu Wang, Yaya Qi, Xiaohong Xian, Dongsheng Chen

“…The gut microbiota, through its production of metabolites and regulation of immune cell functions, plays a vital role in maintaining immune balance and influencing the response to cancer immunotherapies. …”
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Flow-induced mechano-modulation of intestinal permeability on chip by Raffaele Mennella, Sara Sibilio, Francesco Urciuolo, Giorgia Imparato, Paolo A. Netti

“…This is an indispensable feature for designing more biorelevant organ-on-chip models. Here, an intestine-on-chip platform is conceived to mechanically stimulate cells with three different fluid shear stresses and investigate the relative flow-induced changes of molecule transport alongside the resulting epithelial architecture and barrier functionality. …”
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Investigation of rs4994 polymorphism of the β3-adrenergic receptor gene in children with asthma associated with obesity by G. P. Evseeva, E. N. Suprun, R. S. Telepneva, E. B. Nagovitsina, A. E. Poltavchenko, E. V. Rakitskaya, S. V. Suprun, V. K. Kozlov, O. A. Lebed’ko

“…The examination included general clinical, functional, instrumental methods. The study of gene polymorphisms was carried out by the polymerase chain reaction method in real time.Results. …”
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Natural Products from Herbal Medicine Self‐Assemble into Advanced Bioactive Materials by Xiaohang Guo, Weikang Luo, Lingyu Wu, Lianglin Zhang, Yuxuan Chen, Teng Li, Haigang Li, Wei Zhang, Yawei Liu, Jun Zheng, Yang Wang

“…Abstract Novel biomaterials are becoming more crucial in treating human diseases. However, many materials require complex artificial modifications and synthesis, leading to potential difficulties in preparation, side effects, and clinical translation. …”
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Rapid Blood Clot Removal via Remote Delamination and Magnetization of Clot Debris by Qinglong Wang, Ben Wang, Kai Fung Chan, Xin Song, Qianqian Wang, Fengtong Ji, Lin Su, Bonaventure Yiu Ming Ip, Ho Ko, Philip Wai Yan Chiu, Thomas Wai Hong Leung, Li Zhang

“…Here a programmable colloidal microswarm capable of rapidly detaching blood clots from the vessel wall is developed, enabling swift recanalization without the need for complete clot degradation. More importantly, the detached clot debris, despite their random shapes, functions as magnetic “debris‐robots” and can be efficiently propelled through helical swimming within flowing vessels, followed by retrieval using catheter suction. …”
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Assessment of CPME as Sustainable Low VOC Alternative to Hexane: Optimization of Extraction Efficiency and Bioactive Compound Yield from Fenugreek Seed Oil Using Computational and... by Ameni Ben Abdennebi, Emna Chaabani, Mariem Ben Jemaa, Majdi Hammami, Saber Khammassi, Salma Nait Mohamed, Wissem Aidi Wannes, Ibtissem Hamrouni Sellami, Anne-Sylvie Fabiano Tixier, Iness Bettaieb Rebey

“…Importantly, CPME’s low volatile organic compound (VOC) emissions further establish it as a more sustainable and environmentally friendly alternative to hexane, aligning with contemporary goals of reducing harmful emissions in extraction processes. …”
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Differential susceptibility and role for senescence in CART cells based on costimulatory domains by Ismail Can, Elizabeth L. Siegler, Olivia L. Sirpilla, Claudia Manriquez-Roman, Kun Yun, Carli M. Stewart, Jennifer M. Feigin, Makena L. Rodriguez, Omar L. Gutierrez-Ruiz, Ekene J. Ogbodo, Truc N. Huynh, Brooke L. Kimball, Long K. Mai, Mehrdad Hefazi, Lionel Kankeu Fonkoua, Hong Xia, Imene Hamaidi, Berke Alkan, Fatih Sezer, H. Atakan Ekiz, R. Leo Sakemura, Saad S. Kenderian

“…Using CD19-targeted CART cells with costimulation via 4-1BB-CD3ζ (BBζ) or CD28-CD3ζ (28ζ), we showed that CART cells undergo functional, phenotypical, and transcriptomic changes of senescence, which is more prominent in BBζ. …”
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Advanced characterization of biodiesel from Podocarpous falcatus oil via spectroscopy and DFT-based approaches: Thermal degradation kinetics and stability assessment by Serges Bruno Lemoupi Ngomade, Cyrille Donlifack Atemkeng, Aymard Didier Tamafo Fouegue, Cyrille Ghislain Fotsop, Hilaire Tendongmo, Théophile Kamgaing, Solomon Gabche Anagho, Neeraj Atray

“…In contrast, the negative standard entropy (ΔS) indicated a more ordered process. Using density functional theory (DFT) in conjunction with the M05–2X hybrid functional, the computing study was conducted on the two most abundant FAMEs (Fatty acid methyl ester) to achieve the optimum geometry, topology analysis, and electronic properties. …”
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Identification of Immune Related LRR-Containing Genes in Maize (Zea mays L.) by Genome-Wide Sequence Analysis by Wei Song, Baoqiang Wang, Xinghua Li, Jianfen Wei, Ling Chen, Dongmin Zhang, Wenying Zhang, Ronggai Li

“…The identified gene sequences would assist in the study of their functions in maize.…”
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Graham Roberts Study protocol: first ‘trials within cohort study’ for bladder cancer by Mieke Van Hemelrijck, Clare Relton, Harriet Wylie, Fidelma Cahill, Aida Santaolalla, Charlotte Louise Moss, Deborah Enting, Suzanne Amery, Kathryn Chatterton, Muhammad Shamim Khan, Richard T Bryan, Cheryl Gillett, Debra Josephs, Simon Chowdhury, Sarah Rudman, Simon Hughes

“…The following questionnaires will be collected at baseline and every 12 months subsequently: Functional Assessment of Chronic Illness Therapy for Bladder Cancer, the Functional Assessment of Chronic Illness Therapy-Fatigue, the Patient Heath Questionnaire-9, the standardised instrument for a generic health status (EQ-5D-5L), a Short Questionnaire to Assess Health-Enhancing Physical Activity and the Hertfordshire Short Questionnaire to Assess Diet Quality.Ethics and dissemination Due to the nature of this study, we obtained full ethical clearance from the London—Fulham Research Ethics Committee (17/LO1975). …”
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All-dielectric coding metasurface designs for spin-selective beam shaping and multichannel optical vortex beam manipulation by Naeem Ullah, Ata Ur Rahman Khalid, Shahid Iqbal, Muhammad Imran, Muhammad Ismail Khan, Vijay Laxmi, Yibin Tian, Xiaoqing Tian

“…In addition, the convolution operations further augment the functionality of all-dielectric coding metasurfaces, enabling more complex and multichannel manipulations. …”
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