PO09 | Comparison of different aggregometry methods for evaluation of platelet function in patients with myeloproliferative neoplasms

“…Current literature on platelet function in MPN reports conflicting results, mainly due to differences in aggregometry techniques and analytical conditions. …”
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Major nuclear locales define nuclear genome organization and function beyond A and B compartments by Omid Gholamalamdari, Tom van Schaik, Yuchuan Wang, Pradeep Kumar, Liguo Zhang, Yang Zhang, Gabriela A Hernandez Gonzalez, Athanasios E Vouzas, Peiyao A Zhao, David M Gilbert, Jian Ma, Bas van Steensel, Andrew S Belmont

“…Together, our results underscore the importance of considering genome organization relative to nuclear locales for a more complete understanding of the spatial and functional organization of the human genome.…”
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Dairy intake and cognitive function in older adults in three cohorts: a mendelian randomization study by Natalia Ortega, Nick J. Mueller, Abbas Dehghan, Tosca O. E. de Crom, Armin von Gunten, Martin Preisig, Pedro Marques-Vidal, Marco Vinceti, Trudy Voortman, Nicolas Rodondi, Patricia O. Chocano-Bedoya

“…Abstract Background Meta-analyses of observational studies on the effect of dairy on cognitive function have yielded inconclusive results, potentially due to unmeasured confounding. …”
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Mechanical properties and energy absorption of CoCrNi functionally graded TPMS cellular structures by Zhaoyi Wang, Junxian Zhou, Yunzhuo Lu, Dongming Li, Deyu Yue, Xu Zhang, Bingzhi Chen

“…Functionally gradient triply periodic minimal surface (TPMS) structures are found widespread applications in fields such as aerospace and defense engineering, owing to flexible modulation of lightweight and energy-absorbing properties. …”
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Characterization of Arabidopsis thaliana thylakoid lumen 7.6 protein functions in photosystem II assembly by Pan Ren, Ruizi Li, Kai Chen, Chenchen Zheng, Zitian Li, Tao Wang, Cong Ma, Bingyao Li, Xu Wang, Fei Sun, Tengyue Zhang, Yike Xie, Xiaonuan Hao, Huiwen Li, Wenqiang Yang, Aigen Fu, Yaqi Hao

“…Altogether, these results highlight the role of TLP7.6 as an assistive factor in CYP38-mediated PSII assembly, and provide insights into thylakoid lumen protein function in photosynthesis.…”
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Distinct lung function and bronchodilator responses between term and preterm young children with recurrent wheezing by Shen-Hao Lai, Ming-Han Tsai, Man-Chin Hua, Kuo-Wei Yeh, Tsung-Chieh Yao, Jing-Long Huang, Sui-Ling Liao

“…Methods: Children under 2 years of corrected age were enrolled if they had 3 or more wheezing episodes during the enrollment period. …”
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Sex differences in the association between episodic memory residual reserve index and change in executive function by Cheyenne Chooi, Brandon E. Gavett, David Ames, Paul Maruff, Vincent Doré, Victor L. Villemagne, Pierrick Bourgeat, Ying Xia, Colin L. Masters, Ralph N. Martins, Kevin Taddei, Christopher C. Rowe, Michael Weinborn, Stephanie R. Rainey-Smith

“…A three-way interaction was observed between cognitive reserve, brain integrity, and sex on the EF slope. Females benefitted more than males from the protective effects of cognitive reserve at low levels of brain integrity. …”
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Environmental enrichment is associated with favorable memory-related functional brain activity patterns in older adults by Simon Hass, Maxie Liebscher, Anni Richter, Anni Richter, Anni Richter, Klaus Fliessbach, Klaus Fliessbach, Christoph Laske, Christoph Laske, Sebastian Sodenkamp, Sebastian Sodenkamp, Oliver Peters, Oliver Peters, Oliver Peters, Julian Hellmann-Regen, Julian Hellmann-Regen, Julian Hellmann-Regen, Ersin Ersözlü, Ersin Ersözlü, Ersin Ersözlü, Josef Priller, Josef Priller, Josef Priller, Josef Priller, Eike Jakob Spruth, Eike Jakob Spruth, Slawek Altenstein, Slawek Altenstein, Sandra Röske, Anja Schneider, Anja Schneider, Hartmut Schütze, Annika Spottke, Annika Spottke, Anna Esser, Stefan Teipel, Stefan Teipel, Ingo Kilimann, Ingo Kilimann, Jens Wiltfang, Jens Wiltfang, Jens Wiltfang, Ayda Rostamzadeh, Wenzel Glanz, Enise I. Incesoy, Enise I. Incesoy, Enise I. Incesoy, Falk Lüsebrink, Peter Dechent, Stefan Hetzer, Klaus Scheffler, Michael Wagner, Michael Wagner, Frank Jessen, Frank Jessen, Frank Jessen, Emrah Düzel, Emrah Düzel, Franka Glöckner, Björn Hendrik Schott, Björn Hendrik Schott, Björn Hendrik Schott, Miranka Wirth, Olga Klimecki, Olga Klimecki, for DELCODE study group

“…This positive association was observed most strongly in participants with subjective cognitive decline (SCD, n = 199, β = 0.20, p = 0.006).ConclusionMore frequent participation in a variety of leisure activities in early life and midlife is associated with more successful aging of functional brain activity patterns in the memory network of older adults, including participants at increased risk for dementia. …”
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Advances in ethological approaches to explore rodent vocal communication by Ali Abud, Ali Abud, Yihan Wang, Yihan Wang, Yihan Wang, Rechuma Hafter, Ehsan Tavakoli, Christina Wu, Senadee Atapattu, Ahmed Raza, Mohammad Ali, Ali Al-Hadi, Hamza Khalid, Rehmat K. Sukhija, Tobias Stoodley, Alisha Joshi, Samar Joshi, Samar Joshi, Morgan L. Gustison

“…Naturalistic environments were common in function and evolution studies. Adult males were used more often than any other sex and age groups. …”
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MANAGEMENT OF INVESTMENT PROJECTS AS AN IMPORTANT COMPONENT OF ENTERPRISE MANAGEMENT IN THE GLOBAL SPACE by A. V. Nikitina, O. Shersheniuk, I. Kyrchata, K. Popkova, O. Khrystoforova

“…It was emphasized that for the steady positive development of industrial enterprises in a competitive and rapidly changing environment, effective management of investment activity of enterprises is a necessary condition for functioning. In addition, it is proved that in the context of the limited financial and other types of resources, the use of an integrated approach to investing is one more major area for improving the efficiency of management of investment processes at the macro level, and an integrated investment design is a system-integrated process of management of a set of investment projects that are subordinated to a single strategic plan focused on the successful implementation of the enterprise investment program. …”
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Preliminary Test of Source Parameters of M_wp6 Italian Earthquakes: Revisiting Kinematic Function Method by Paolo Harabaglia, Massimiliano Iurcev, Denis Sandron, Teresa Tufaro, Marco Vona, Franco Pettenati

“…The 1928 event is located a few tens of kilometers west of the more destructive M_w6.5 of 6 May 1976 and northeast of the subsequent earthquake M_wp6.1 of 18 October 1936. …”
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Variation in near‐surface soil temperature drives plant assemblage differentiation across aspect by Elizabeth G. Simpson, Ian Fraser, Hillary Woolf, William D. Pearse

“…In contrast, we found more functionally dispersed assemblages, that were taller and more resource‐acquisitive on north‐facing slopes where intra‐annual temperature was cooler and less variable. …”
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Evaluation of phenotypic and functional stability of RAW 264.7 cell line through serial passages. by Bartłomiej Taciak, Maciej Białasek, Agata Braniewska, Zuzanna Sas, Paulina Sawicka, Łukasz Kiraga, Tomasz Rygiel, Magdalena Król

“…The monocyte/macrophage-like cell line RAW 264.7 has been one of the most commonly used myeloid cell line for more than 40 years. Despite its phenotypic and functional stability is often discussed in literature or at various scientific discussion panels, their stability during the consecutive passages has not been confirmed in any solid study. …”
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Proximal tubular deletion of superoxide dismutase-2 reveals disparate effects on kidney function in diabetes by Inez A. Trambas, Lilliana Bowen, Vicki Thallas-Bonke, Matthew Snelson, Karly C. Sourris, Adrienne Laskowski, Michel Tauc, Isabelle Rubera, Guoping Zheng, David C.H. Harris, Phillip Kantharidis, Takahiko Shimizu, Mark E. Cooper, Sih Min Tan, Melinda T. Coughlan

“…We hypothesized that maintenance of MnSOD function in the proximal tubules would be critical to maintain kidney health in diabetes. …”
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Biochar and Kitchen Stove Ash for Improving Nutrient Availability and Microbial Functions of Tropical Acidic Soil by Isaac Asirifi, Lars Makarowsky, Stefanie Heinze, Michael Herre, Steffen Werner, Kwame Agyei Frimpong, Robin Pierburg, Bernd Marschner

“…The ash supplied minerals (P, K, and Mg) provided a more beneficial effect on the soil’s nutrient content and microbial functions than the calcium carbonate. …”
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Intestinal microbiota in obese children with non-alcoholic fatty liver disease depending on the gallbladder function by Yu. M. Stepanov, N. Yu. Zavhorodnia, O. M. Tatarchuk, I. A. Klenina, O. I. Hrabovska, E. V. Zyhalo, O. P. Petishko, N. S. Vishnarevska, V. V. Dolhopolova

“…To determine the features of the intestinal microbiota in obese children with non-alcoholic fatty liver disease (NAFLD) depending on the functional state of the gallbladder. Materials and methods. …”
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Dynamics of Kidney Function in Patients with Chronic Kidney Disease and Atrial Fibrillation Who Receive Dabigatran by N. A. Novikova, Z. K. Salpagarova, M. I. Chashkina, A. A. Bykova, Z. A. Alimova, А. S. Yadykina, D. F. Mesitskaya, N. A. Babakova, D. A. Andreev

“…Changes in the renal function shall mean a decrease or increase in GFR by ≥5 ml/min.Results. …”
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Integration and functionality of human iPSC-derived microglia in a chimeric mouse retinal model by Chun Tang, Qi-Qi Zhou, Xiu-Feng Huang, Ya-Yi Ju, Bi-Lin Rao, Zhi-Cong Liu, Yi-An Jia, Zhan-Pei Bai, Qing-Yang Lin, Lin Liu, Jia Qu, Jun Zhang, Mei-Ling Gao

“…Our approach achieved over 86% integration of human microglia, which maintained key functions including proliferation, immune responsiveness, and synaptic pruning over a 14-day culture period. scRNA-seq of xMG revealed a shift in microglial signatures compared to monoculture iMG, indicating a transition to a more in vivo-like phenotype. …”
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Identification, Characterization, Expression Profiling and Functional Analysis of Tobacco <i>CalS</i> Gene Family by Hong Wang, He Meng, Xiaohan Qi, Yi Pan, Bailu Ji, Liuying Wen, Yanjun Zan, Huan Si, Yuanying Wang, Dan Liu, Aiguo Yang, Zhengwen Liu, Lirui Cheng

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Taxonomic and functional β-diversity of Collembola across elevational and seasonal gradients on a temperate mountain by Zhijing Xie, Jian Zhang, Yuhao Zhao, Dingliang Xing, Yunga Wu, Johannes Lux, Liang Chang, Kangle Lu, Xin Sun, Donghui Wu, Stefan Scheu

“…The turnover components dominated taxonomic β-diversity across seasons, whereas the nestedness component contributed more to functional β-diversity. Furthermore, the local contribution to overall incidence-based taxonomic β-diversity followed a pronounced U-shaped pattern, indicates that lower and higher elevations significantly contribute to the biodiversity of Collembola communities. …”
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