Effect of a clinical decision support system for non-valvular atrial fibrillation on improving appropriate anticoagulation treatment in China’s primary care: a cluster randomized c... by Xueying Ru, Tianhao Wang, Jian Gao, Junling Gao, Bin Kong, Qian Du, Yunhui Ma, Zhigang Pan

“…The intervention group showed a tendency of less bleeding and composite adverse outcomes. Conclusions The utilization of GP-CDSS-2.0 in primary care had the potential to raise the proportion of appropriate anticoagulation among patients with AF. …”
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Spatial transcriptomic analysis across histological subtypes reveals molecular heterogeneity and prognostic markers in early‐stage lung adenocarcinoma by Hua Geng, Wenhao Zhou, Haitao Luo, Jiaqian Wang, Shixiong Li, Congcong Song, Yujie Zhao, Meilin Xu

“…We integrated these pathways to develop a composite molecular signature that strongly correlate with adverse prognosis. …”
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Contribution of cardio-ankle vascular index to prediction of cardiovascular events in the adult urban population: data from the ESSE-RF study (Tomsk) by A. R. Zairova, A. N. Rogoza, E. V. Oshchepkova, E. B. Yarovaya, V. A. Kutsenko, S. A. Shalnova, I. A. Trubacheva, V. S. Kaveshnikov, V. N. Serebryakova, S. A. Boytcov

“…We revealed that prior myocardial infarction or stroke (n=52) is associated with an increase in CVE incidence from 2,3 to 11,5% (p=0,0003) and from 5% to 23% (p<0,001) for primary and secondary composite endpoints, respectively. In a group of 1290 people (without prior MI or stroke), CAVI was significantly higher in men than in women: 7,4±1,4 vs 7,1±1,3 (p=0,002), despite more young age: 45,4±11,8 vs 48,0±11,3 years (p<0,001). …”
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Assessing intrinsic capacity for person‐centred HIV care: a cross‐sectional study in ageing populations in Malaysia and Hong Kong by Reena Rajasuriar, Syaza Hisham, John Son Lim, Jean Yi Cheong, Wen Ying Ho, Siew Hwei Yap, Nurul Syuhada Zulhaimi, Malinee Neelamegam, Catherine Cheung, Vivian Wong, Ruhana Che Yusof, Kejal Hasmukharay, Shahrul Bahyah Kamaruzzaman, Sharifah Faridah Syed Omar, Meng Li Chong, Pui Li Wong, Grace Chung‐Yan Lui

“…IC scores performed well in identifying PWH with frailty (AUC‐ROC ≥ 0.80) in the HK and Malaysian cohorts but more modestly (AUC‐ROC ≥ 0.64) for IADL deficits. …”
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Features of short-term heart rate variability in internally displaced people with type 2 diabetes mellitus by V.A. Serhiyenko, V.B. Sehin, V.I. Pankiv, A.A. Serhiyenko

“…The data obtained can become the basis for the development of effective prevention strategies, as well as new methods of timely diagnosis and therapy of IDP with T2DM.…”
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Tumor mutational burden and survival on immune checkpoint inhibition in >8000 patients across 24 cancer types by Vivek Subbiah, Samuel J Klempner, Neeraj Agarwal, David P Carbone, Amit Mahipal, Shilpa Gupta, David Fabrizio, Jeffrey S Ross, Gerald Li, David R Gandara, Miles C Andrews, Jonathan W Riess, Ramez N Eskander, Ryon P Graf, Geoffrey R Oxnard, Sarah Sammons, Jeremy Snider, Lilia Bouzit, Cheryl Cho-Phan, Megan Price, Julia C F Quintanilha, Richard Sheng Poe Huang

“…Exploratory assessments of patients receiving ICI+chemotherapy (n=4369) observed more favorable rwOS only in TMB≥20.Conclusions Across >8000 patients treated with single-agent ICI, and within individual cancer types with sufficient power, elevated TMB based on the FDA-approved CDx was associated with more favorable rwOS compared with similar patients with lower TMB levels. …”
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Cardiac arrest while using the toilet: not uncommon and associated with adverse resuscitation profile by Elizabeth D. Paratz, Carl Johann Hansen, Andre La Gerche, Dion Stub, Ziad Nehme, Ashanti Dantanarayana, Kelila Freedman, Andreas Pflaumer, Jodie Ingles, Bo Gregers Winkel, Jacob Tfelt-Hansen

“…Australians experienced toilet-associated OHCA 1.7 times more frequently than Danes (4.1 % vs 2.4 %, p = 0.016). …”
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Identifying high-risk Fontan phenotypes using K-means clustering of cardiac magnetic resonance-based dyssynchrony metrics by Addison Gearhart, Sunakshi Bassi, Rahul H. Rathod, Rebecca S. Beroukhim, Stuart Lipsitz, Maxwell P. Gold, David M. Harrild, Audrey Dionne, Sunil J. Ghelani

“…Clusters were compared for demographic, anatomical, and composite outcomes of death, or heart transplantation. …”
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Simulated Cam Morphology of the Hip Changes Sacroiliac Motion During Hip Motion and Loading in a Cadaveric Model by Mason E. Uvodich, M.D., Alex W. Hooke, M.A., Zachary V. Braig, M.D., Micah J. Nieboer, M.D., Evan M. Dugdale, M.D., William W. Cross, M.D., Aaron J. Krych, M.D., Mario Hevesi, M.D., Ph.D.

“…Outcomes included translational and rotational movement about 3 axes and composite (total) translational motion at the ipsilateral sacroiliac (SI) joint. …”
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Biventricular longitudinal strain analysis using cardiovascular magnetic resonance feature-tracking: Prognostic value in Eisenmenger syndrome by Chao Gong, Chen Chen, Xuhan Liu, Ke Wan, Jiajun Guo, Juan He, Lidan Yin, Bi Wen, Shoufang Pu, Yucheng Chen

“…Kaplan–Meier analysis indicated that patients with both lower absolute values of LV GLS and RV FWLS were more likely to be at an even higher risk of composite endpoints (p <0.001). …”
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Evaluation of Silk Fibroin-RGD-Stem Cell Factor Scaffold Effect on Adhesion, Migration, and Proliferation of Stem Cells of Apical Papilla by Jie Wei, Xiao-Qiang Sun, Ben-Xiang Hou

“…Furthermore, the numbers of SCAPs on the scaffolds were counted by a digestion counting method to evaluate their proliferation. Cells on the SF-RGD-SCF scaffold proliferated more than those on the other scaffolds and showed a more obvious tendency to migrate to the scaffold’s deep porous structure after 7 d seeding. …”
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ROS‐Activated Nanohydrogel Scaffolds with Multi‐Factors Controlled Release for Targeted Dual‐Lineage Repair of Osteochondral Defects by Xiuhui Wang, Shunli Wu, Ruiyang Li, Huijian Yang, Yue Sun, Zijie Cao, Xiao Chen, Yan Hu, Hao Zhang, Zhen Geng, Long Bai, Zhongmin Shi, Ke Xu, Hongbo Tan, Jiacan Su

“…Herein, ROS‐activated nanohydrogels composite bilayer scaffolds with multi‐factors controlled release are rationally designed using the combination of 3D printing and gelatin placeholder methods. …”
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Stabilization effect and mechanism of heavy metals by microbial consortium of phosphate-solubilizing bacteria and urease-producing bacteria by Xuezhe Zhu, Xuezhe Zhu, Xuezhe Zhu, Xuezhe Zhu, Xuezhe Zhu, Xuezhe Zhu, Yupin Zhou, Yupin Zhou, Yupin Zhou, Yupin Zhou, Yupin Zhou, Yupin Zhou, Zhenghao Yan, Yongfang Yan, Shuangquan Li, Shuangquan Li, Shuangquan Li, Shuangquan Li, Shuangquan Li, Mingjiao Yu, Mingjiao Yu, Mingjiao Yu, Mingjiao Yu, Mingjiao Yu, Xiao Yan, Xiao Yan, Xiao Yan, Xiao Yan, Xiao Yan, Mingjiang Zhang, Mingjiang Zhang, Mingjiang Zhang, Mingjiang Zhang, Mingjiang Zhang

“…The microstructural and compositional changes during the biostabilization process were more deeply analyzed using XRD, FT-IR and SEM-EDS.Results and discussionThe precipitation of heavy metals could be promoted effectively when soluble starch (10.2 g/L) was used as carbon source and urea (7.8 g/L) as nitrogen source. …”
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Immune-neuroendocrine crosstalk in mood and psychotic disorders: A meta-analysis and systematic review by Minne Van Den Noortgate, Filip Van Den Eede, Violette Coppens, Erik J. Giltay, Livia De Picker, Manuel Morrens

“…Our objective was to perform an up to date systematic review and meta-analysis of the association between hypothalamic-pituitary-adrenal (HPA) axis and immune system functioning in mood and psychotic disorders. Methods: We searched the Pubmed, Web of Science and Embase databases for studies reporting correlations between one or more HPA- and immune markers (IM) in patients with mood or psychotic disorders. …”
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Fixed-Bed Adsorption of an Azo Dye (Methyl Orange) onto Chemically and Thermally Regenerated Activated Carbons by Idriss Kamdem Taquieteu, Hermann Tamaguelon Dzoujo, Victor Odhiambo Shikuku, Charles Banenzoué, Daniel David Joh Dina

“…In this study, the effectiveness of the recovery method for spent granular activated carbon (SGAC) for application in dye removal was evaluated. …”
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Synthesis, spectroscopic characterization and biological applications of some novel Schiff base transition metal (II) complexes derived from curcumin moiety by T.J. Saritha, P. Metilda

“…Result found that the metal complexes were more active than the ligand. Also anti-inflammatory activity of Schiff base complexes were studied by protein denaturation method and result reveals that Zn(II) complex shows more activity.…”
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Anisotropic flexible stress sensors based on Loofah/CN/MWCNTs by 刘璐, 贾晓丽, 黄书童, 张景龙, 李守宝, 柯燎亮

“…Nine groups of MWCNTs/CN suspensions, each with a volume of 500 ml, were prepared according to the compositions listed in Table 2. Figure 2 illustrates the preparation of Loofah/CN/MWCNTs composites through a simple dipping-drying method. …”
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A blood‐based nutritional risk index explains cognitive enhancement and decline in the multidomain Alzheimer prevention trial by Gene L. Bowman, Hiroko H. Dodge, Sophie Guyonnet, Nina Zhou, Juliana Donohue, Aline Bichsel, Jeroen Schmitt, Claudie Hooper, Tamas Bartfai, Sandrine Andrieu, Bruno Vellas, MAPT/DSA Study Group, Bruno Vellas, Sophie Guyonnet, Isabelle Carrié, Lauréane Brigitte, Catherine Faisant, Françoise Lala, Julien Delrieu, Hélène Villars, Emeline Combrouze, Carole Badufle, Audrey Zueras, Sandrine Andrieu, Christelle Cantet, Christophe Morin, Gabor Abellan Van Kan, Charlotte Dupuy, Yves Rolland, Céline Caillaud, Pierre‐Jean Ousset, Françoise Lala

“…Abstract Introduction Multinutrient approaches may produce more robust effects on brain health through interactive qualities. …”
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Assessment of Organic Matter Influence on the Ecological Integrity of Poyang Lake Using O/E Model and Chemical–Biological Indices over the Past Two Decades by Jindong Wang, Wenjie Huang, Chenglian Feng, Hongyang Wang

“…The results showed that the benthic community structure is simple, and the biodiversity is low, which is mainly dominated by Insecta in Arthropoda and Oligochaeta in Oroidea, accounting for 84.3% and 42.4%, respectively; the results of the O/E index evaluated under the threshold of probability of capture ≥ 0.5 showed that the health grade of all sections was sub-healthy or average, which was consistent with the results of the chemical–biological composite index evaluation. The dual evaluation method of the O/E model and chemical–biological composite index adopted in this study integrates more than twenty years of long-time scale data; this method combined with long time scale data has not been studied before, and its advantage is that it can more objectively show the change in the ecological situation of Poyang Lake for many years. …”
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The effect of pre- and post-harvesting techniques on phenolics, antioxidant activities and key enzyme inhibitions of commercially available ready-to-drink teas by Chanakan Khemthong, Sirinapa Thangsiri, Wimonphan Chathiran, Woorawee Inthachat, Chaowanee Chupeerach, Piya Temviriyanukul, Nattira On–Nom, Warangkana Srichamnong, Uthaiwan Suttisansanee

“…However, knowledge about the impact of these processing methods on the phenolic compositions and health properties of commercially available ready-to-drink teas is limited. …”
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