The role of CD47 in immune escape of colon cancer and its correlation with heterogeneity of tumor immune microenvironment by Qiu-Si Tian, ChunMei Zhang, Zhi-Jun Bao, ZhiGang Pei

“…Higher CD47 expression was significantly associated with more advanced tumor stages, including TNM staging, T staging, and N staging (P < 0.05). …”
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Health care professionals intention to use digital health data hub working in East Gojjam Hospitals, Northwest Ethiopia: Technology acceptance modeling. by Ayenew Sisay Gebeyew, Sefefe Birhanu Tizie, Bayou Tilahun Assaye, Afework Edmealem, Temesgen Feyu, Habtamu Mekonen, Tirsit Ketsela Zeleke, Melese Getachew, Andualem Fentahun

“…Structural equation modeling (SEM) was used for the analysis. Because it is a more powerful multivariate technique for testing and evaluating multivariate causal relationships. …”
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Safety and Efficacy of Mirogabalin in Lumbar Spinal Stenosis Patients with Peripheral Neuropathic Pain on NSAIDs: Post Hoc Analysis of the MiroTAS Study by Takuya Nikaido, Shunsuke Tabata, Kazuhito Shiosakai, Taichi Nakatani, Hiroshi Sakoda

“…Abstract Introduction The primary analysis of the MiroTAS study in patients with lumbar spinal stenosis (LSS) taking non-steroidal anti-inflammatory drugs showed that mirogabalin add-on therapy further improved pain and quality of life (QOL) without new safety concerns. Methods This post hoc analysis of the MiroTAS study examined the timing of onset of mirogabalin-related adverse drug reactions (mrADRs) (composite of somnolence, dizziness, edema, and peripheral edema), factors affecting safety and efficacy, and the relationships between baseline numbness severity (by spine painDETECT questionnaire [SPDQ] score), EQ-5D-5L scores, leg pain improvement (by visual analogue scale [VAS]), and patient satisfaction (by Patient Global Impression of Change [PGIC] scores). …”
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Socioeconomic and racial-ethnic disparities in flame retardant exposure and executive function skills in preschool children by Alexis Merculief, Megan McClelland, Stephanie Foster, John Geldhof, Shannon Lipscomb, Kim Anderson, Molly L. Kile

“…Furthermore, socioeconomic disadvantage was more strongly associated with reduced EF than either PBDE or OPFR exposures. …”
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Evaluation of the marginal fit and fracture resistance of interim restorations fabricated using different techniques: an in vitro study by Mostafa Elashkar, Yehia Aboushady, Merna Ihab, Mohamed T. El Halawani

“…Aim The aim of this in vitro study was to investigate the marginal fit and fracture resistance of manually fabricated, computer-aided design and computer-aided manufacturing (CAD/CAM) milled, and CAD/CAM three-dimensionally (3D) printed 3-unit interim fixed dental prostheses (FDPs). Materials and methods Sixty-four 3-unit interim FDPs were fabricated on epoxy resin models using different fabrication techniques: manual fabrication with poly methyl methacrylate (PMMA) (n = 16), manual fabrication with Bis-acrylic composite resin (n = 16), CAD/CAM milling (n = 16), and CAD/CAM 3D-printing with a digital light processing (DLP) printer (n = 16). …”
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Trends in Complications Among Patients Undergoing Aortic Valve Replacement in the United States by James E. Harvey, Samir R. Kapadia, David J. Cohen, Ankur Kalra, William Irish, Candace Gunnarsson, Michael Ryan, Soumya G. Chikermane, Christin Thompson, Rishi Puri

“…These reductions were more pronounced for TAVR (41% to >19%, Δ=22%) than SAVR (51% to >47%, Δ=4%). …”
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Device measured physical activity before pregnancy and the risk of adverse pregnancy outcomes in the HUNT study: a population-based cohort study by Laura Vatn Slapgaard, Signe Nilssen Stafne, Vegar Rangul, Ingrid Aanesland Dahle, Julie Horn

“…We aimed to examine the association between objectively measured physical activity before pregnancy and risk of APOs. Methods The study population consisted of women with one or more singleton births registered in the Medical Birth Registry of Norway (MBRN) after participating in the fourth survey of the Trøndelag Health Study (HUNT4, 2017–2019). …”
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Sex Difference in Coronary Artery Spasm Tested by Intracoronary Acetylcholine Provocation Test in Patients with Nonobstructive Coronary Artery Disease by Ji Young Park, Se Yeon Choi, Seung-Woon Rha, Byoung Geol Choi, Yung-Kyun Noh, Yong Hoon Kim

“…In CAS patients, there was no statistical differences for various individual and composite major outcomes up to five years in either men or women. …”
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A data science pipeline applied to Australia's 2022 COVID-19 Omicron waves by James M. Trauer, Angus E. Hughes, David S. Shipman, Michael T. Meehan, Alec S. Henderson, Emma S. McBryde, Romain Ragonnet

“…These packages can support infectious disease modelling to be more robust, efficient and transparent, which has been particularly important during the COVID-19 pandemic. …”
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Real-World Effectiveness of Bebtelovimab Versus Nirmatrelvir/Ritonavir in Outpatients with COVID-19 by Christopher G. Rowan, Russell M. Nichols, Neil Dhopeshwarkar, Jennifer M. Alyea, Baojin Zhu, Sengwee Toh, K. Arnold Chan, Elsie L. Grace

“…BEB-treated patients were older and had more comorbidities compared to NR-treated patients prior to matching. …”
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Rationale and design of randomized non-inferiority clinical trial to compare the safety and efficacy of ticagrelor monotherapy with dual antiplatelet therapy in chronic coronary sy... by Seyed Alireza Mirhosseini, Mohammadreza Akbari, Davar Aldavood, Hooyar Zarifkar, Armin Attar, Javad Kojuri

“…While current guidelines recommend dual antiplatelet therapy (DAPT) with aspirin and clopidogrel, the development of drug-eluting stents (DES) and more potent agents has sparked interest in shorter DAPT regimens, followed by P2Y12 inhibitor monotherapy, as a potential alternative. …”
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Nanopore Characteristics of the Cambrian Niutitang Formation Organic-Rich Shales in the Middle Yangtze Region and Its Formation Controlling Factors by Jie Xu, Weihua Guo, Bin Yang, Dongxu Ma, Li Zhao, Haotian Liu, Hongjie Ji, Huifei Tao

“…The laser Raman, X-ray diffraction analysis, FE-SEM, and low-pressure N2 and CO2 adsorption methods are used to study the geochemical and mineral compositions of the shales, and the nanopore characteristics and its formation controlling factors of the shales are discussed. …”
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Study on the Cutter–Granite Interaction Mechanism in High-Temperature Geothermal Wells by Yan Yang, Dongdong Song, Kuilin Huang, Haitao Ren, Yingxin Yang, Shunzuo Qiu, Zequan Huang

“…Among them, the interaction between the cutter of the drill bit and the rock is the key factor determining the rock-breaking efficiency of PDC (Polycrystalline Diamond Composite) drill bits. To further explore the rock-breaking mechanism of cutters on granite, this study adopts a combination of experimental and simulation methods to conduct systematic research. …”
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Intrinsic capacity trajectories and cardiovascular disease incidence among Chinese older adults: a population-based prospective cohort study by Zhiting Guo, Yuling Chen, Binu Koirala, Jiaying Li, Yingying Jia, Cheryl R. Dennison Himmelfarb, Jingfen Jin

“…Abstract Background Intrinsic capacity (IC), a composite of physical and mental capacities, is a marker of healthy aging. …”
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Predictive value of systemic immune inflammation index combined with coagulation index in traumatic coagulopathy in patients with severe trauma by Chen Wang, Yongyong Huang, Shiyun Liao, Jiming Song

“…By monitoring these indexes, we can more accurately predict the occurrence of TIC and take effective treatment measures in time.…”
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Designing model of place branding based on brand attachment (Kish Island case study) by khadigeh Ghaemmaghami Tabrizi, Asghar Moshabaki Esfahaniَ, Abdolah Naami, Naser Azad

“…The sense of attachment to Kish Island due to the relaxation and positive energy of Kish Island due to the liveliness of the island soil (being coral), tourists' satisfaction (or a sense of beyond satisfaction with the island) and the desire to continues interactions (as more travel, sightseeing and shopping) to prosper The more tourism on the island.The more famous and attractive a place is, the more it expands the tourism industry, and the island becomes the top tourist destination for travelers. …”
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A survey of pediatric dentists' caries-related treatment decisions and restorative modalities – A web-based survey by Hassan S. Halawany, Fouad Salama, Vimal Jacob, Nimmi Biju Abraham, Tarfa Nasser Bin Moharib, Abdulfatah Samih Alazmah, Jawaher Abdulaziz Al Harbi

“…Esthetic pediatric crowns were more utilized by male compared to female participants. …”
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Adherence to oral anticoagulation in ischemic stroke patients with atrial fibrillation by Paula Tiili, Ioannis Leventis, Janne Kinnunen, Ida Svedjebäck, Mika Lehto, Efstathia Karagkiozi, Dimitrios Sagris, George Ntaios, Jukka Putaala

“…Background Non-vitamin K antagonist oral anticoagulants (NOAC) have superior safety and comparable efficacy profile compared to vitamin-K antagonists (VKAs), with more convenient dosing schemes. However, issues with adherence to the NOACs remain unsolved.Aims We sought to investigate the adherence to oral anticoagulation (OAC) and baseline factors associated with poor adherence after ischaemic stroke in patients with atrial fibrillation (AF).Methods We recruited hospitalised patients (2013–2019) from two prospective stroke registries in Larissa and Helsinki University Hospitals and invited survived patients to participate in a telephone interview. …”
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Effects of Once-Weekly Semaglutide on Kidney Disease Outcomes by KDIGO Risk Category in the SUSTAIN 6 Trial by Katherine R. Tuttle, Stephen C. Bain, Heidrun Bosch-Traberg, Kamlesh Khunti, Søren Rasmussen, Ekaterina Sokareva, David Z. Cherney

“…Participants receiving semaglutide were more likely to move to a lower KDIGO risk category (odds ratio: 1.69; 95% CI: [1.32–2.16]) and less likely to move to a higher KDIGO risk category versus placebo (odds ratio: 0.71; 95% CI: [0.59–0.86]). …”
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Maternal and neonatal outcomes of Group B Streptococcus colonization: a retrospective study by Guixiu Jin, Lanhua Liu, Xiaolong Wang, Junling Fei, Zhenling Zhu, Ziyan Jiang, Min Liu

“…Diabetic pregnant women were more likely to become colonized with GBS. Our research revealed that GBS carriers experienced higher rates of fetal distress and neonatal adverse outcomes than non-GBS carriers. …”
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