Bedaquiline, pretomanid, linezolid, and moxifloxacin (BPaLM) for multidrug- or rifampin-resistant tuberculosis: a systematic review by Denise Rossato Silva, Flávia Fonseca Fernandes, Juliana Carvalho Ferreira, Wanderley Bernando, Margareth Maria Pretti Dalcolmo, Fernanda Dockhorn Costa Johansen, Fernanda Carvalho de Queiroz Mello

“…Conclusions: This systematic review of the use of BPaLM in patients with MDR/RR-TB, although it included only one study, showed that BPaLM is more effective than is the standard of care and has a better safety profile. …”
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Pubertal timing: A life course pathway linking early life risk to adulthood cardiometabolic health. by Maria E Bleil, Bradley M Appelhans, Steven E Gregorich, Robert A Hiatt, Glenn I Roisman, Cathryn Booth-LaForce

“…These findings have important implications for novel opportunities for increased surveillance and potential intervention focusing on pubertal development as a target to improve health more broadly.…”
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Factors influencing the self-management ability among older adults experiencing intrinsic capacity decline: a cross-sectional study by Qingcai Liu, Xiaoyang Li, Mingyue Hu, Yinan Zhao, Shuang Wu, Hui Feng

“…There were significant associations between age, perceived social support, and intrinsic ability composite score with self-management abilities (Age: β = −0.263; p < 0.001; social support: β = 0.291; p < 0.001; intrinsic capacity composite score: β = 0.179; p < 0.001). …”
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Enhanced external counterpulsation in the management of patients with ischemic heart failure: long-term impact on clinical outcomes by A. S. Lishuta, E. V. Privalova, Yu. N. Belenkov

“…The odds ratio for primary and composite endpoint in group 1 was 0,207 (95% confidence interval: 0,090-0,475; p<0,001) and 0,032 (95% confidence interval 0,002-0,553; p=0,018).Conclusion. …”
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Superior cardiovascular protection with GLP-1 RAs over SGLT2 inhibitors in DM and HFpEF: A propensity score matching study. by Allen Cheng-Wei Li, Yang-Chi Lin, Jing-Yang Huang, Lung-Ching Chen, Su-Kiat Chua

“…Outcomes assessed over three years were a composite of all-cause mortality and progression to systolic heart failure, acute myocardial infarction, or stroke.…”
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Selection of In Vivo Relevant Dissolution Test Parameters for the Development of Cannabidiol Formulations with Enhanced Oral Bioavailability by Nathan Koch, Quentin Bourcy, Olivier Jennotte, Patrice Chiap, Anna Lechanteur, Jean-Michel Cardot, Brigitte Evrard

“…Neutral media enabled a relatively good prediction of the extent of absorption observed in vivo, whereas the rate of absorption was more complicated to predict. <b>Conclusions:</b> FeSSIF media, and FaSSIF sink media to a lesser extent, were the only compositions enabling predictions of both extent and rate, indicating that emulsification is possibly a major contributor to the in vivo availability of the drug.…”
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A 48-month clinical performance of hybrid ceramic fragment restorations manufactured in CAD/CAM in non-carious cervical lesions: case report by Michael Willian Favoreto, Gabriel David Cochinski, Eveline Claudia Martini, Thalita de Paris Matos, Matheus Coelho Bandeca, Alessandro Dourado Loguercio

“…From the restorative perspective, various methods are available to prevent the progression of non-carious cervical lesions. …”
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Stackable 3D-printed core-shell nozzle system for multi-shell fiber and microdroplet generation by Jianfeng Li, Peer Fischer

“…Microfluidics is increasingly utilized in biofabrication to create more complex fiber and droplet structures, including those that involve multiple materials. …”
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Multi-Indicator Comprehensive Quality Evaluation of <i>Turpinia arguta</i> (Lindl.) Seem Herbs at Different Harvesting Periods by Jiangmei Hu, Junhuo Cai, Qiangqiang Cheng, Lijun Wang, Xinrui Hu, Wenzhao Wang, Zhifeng Liao, Xiuhua Tao

“…This study aimed to investigate differences in the leaf biomasses, chemical compositions, and pharmacological activities of <i>Turpinia arguta</i> histocultured seedlings and live seedlings at different harvesting periods (S1, S2, S3, and S4) in order to determine the optimal harvesting period. …”
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Optimization of Extraction Parameters for Phenolics Recovery from Avocado Peels Using Ultrasound and Microwave Technologies by Lorena Martínez-Zamora, María Carmen Bueso, Mathieu Kessler, Rosa Zapata, Perla A. Gómez, Francisco Artés-Hernández

“…This study optimized the extraction parameters of phenolics using ultrasound- (UAE) and microwave-assisted technologies (MAE) with a Central Composite Design (CCD). Methods: The extraction variables included EtOH concentration (0–100%), temperature (13–47 °C for UAE and 55–95 °C for MAE), and time (3–37 min for UAE and 3–27 min for MAE). …”
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Associations between new-onset postoperative atrial fibrillation and changes in left ventricular mass index in patients undergoing transcatheter aortic valve replacement by Hua-Jie Zheng, Jun Li, Ling-Feng Tang, Mei Guo, Ya-Nan Wei, Wei Cheng

“…Therefore, clinicians should be more proactive in monitoring and treating POAF after TAVR.…”
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Transcatheter Aortic Valve Replacement and Surgical Aortic Valve Replacement Outcomes in Left Ventricular Assist Device Patients with Aortic Insufficiency by Aniket S Rali, Siva S Taduru, Lena E Tran, Sagar Ranka, Kelly H Schlendorf, Colin M Barker, Ashish S Shah, JoAnn Lindenfeld, Sandip K Zalawadiya

“…We observed a significantly higher prevalence of the primary composite outcome in patients undergoing SAVR (30%) compared with TAVR (14.3%; p=0.001). …”
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Structure and mineralization potential of the southwestern part of Sokoto Basin in Nigeria by U. Z. Magawata, U. Z. Magawata, N. K. Olasunkanmi, G. B. Egbeyale, A. Saleh

“…The integration of geophysical and remote sensing methods provides a more detailed and spatially extensive understanding of the subsurface geology compared to traditional field-based mapping, offering valuable insights for future mineral exploration and a refined geological interpretation of the Sokoto Basin.…”
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A Prospective double-blind, randomised controlled trial comparing angiotensin II to norepinephrine to reduce length of hospital stay in cardiac surgery patients (the PORTHOS study... by Rinaldo Bellomo, Eldho Paul, David Pilcher, Silvana F Marasco, Lachlan F Miles, Tim G Coulson, Daniel Frei

“…Furthermore, hyperreninaemic patients were more sensitive to angiotensin II. These findings support the need for a larger RCT to determine whether angiotensin II is superior to norepinephrine as a first-line treatment for low blood pressure after cardiac surgery.Methods and analysis We will conduct a double-blind RCT comparing an infusion of either angiotensin II or norepinephrine intraoperatively and for up to 48 hours after the start of surgery. …”
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A Review of the Application of Poly (Lactic-Co-Glycolic Acid) Copolymers in Bone Tissue Regenerative Medicine by Alireza Davaripour, Mohsen Shahrousvand, Jamshid Mohammadi-Rovshandeh, Seyed Mohammad Davachi

“…However, in cases where the damage is extensive or there is no possibility of spontaneous repair, the need for more advanced methods becomes necessary. Bone tissue engineering is proposed as a new approach for repairing damaged bones and includes material science, biomechanics, immunology, and biology. …”
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The effect of platinum-aluminide coating features on high-temperature fatigue life of nickel-based superalloy Rene®80 by Barjesteh M.M., Zangeneh-Madar K., Abbasi S.M., Shirvani K.

“…The results of microstructure investigations performed by scanning electron microscope and X-ray diffraction phase analysis indicated a three-layer structure for the coating (bi-phase (Ni,Pt)Al+PtAl2, single-phase (Ni,Pt)Al and interdiffusion zone) with different chemical compositions at both thicknesses of the platinum layer and using both aluminizing methods. …”
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A sustainable delamination approach for simultaneous separation and leaching of cathodes from end-of-life Li ion batteries by Pietro Cattaneo, Daniele Callegari, Fiorenza D'Aprile, Eliana Quartarone

“…A more refined approach to LIBs recycling includes the dismantling and the sorting of their components, allowing for a targeted extraction.The spent cathodes recycling process here presented involves the simultaneous delamination from the current collector and the leaching (>95 %) of the cathode active material (CAM) in a citric acid solution, enabling also the recovery of Polyvinylidene fluoride (PVDF) and Carbon filler as unleached residues, which can be used as a composite binder for new electrodes manufacturing. …”
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Review and application prospect of natural gas pipeline network system resilience research by Zhaoming YANG, Qi XIANG, Huai SU, Jinjun ZHANG

“…Additionally, the research progress and existing issues in the determination of NGPNS resilience indicators, modeling and solution methods were summarized and analyzed, and the optimization and improving methods of NGPNS resilience were discussed. …”
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Educational Attainment and the Effect of Intensive Blood Pressure Reduction: A Post Hoc Analysis of the SPRINT Study by Joshua Garfein, Akira Sekikawa, Andrew Mrkva, Djhenne Dalmacy, Jarett D. Berry, Yordanos M. Tiruneh, Jared W. Magnani

“…Those with higher education were more likely to be older, men, and White race. During follow‐up, SBP was nearly identical across categories of education. …”
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Association between different proportions of crescents and adverse renal outcomes in immunoglobulin a nephropathy: a systematic review and meta-analysis by Zhiyun Zang, Kewei Fang, Niya Ma, Yunyun Zhang, Ying Shu, Zi Li

“…Compared to the C0 or C1 group, the C2 group was more likely to have composite kidney endpoint and ESRD. …”
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