Severity of native pulmonary annular hypoplasia and late outcomes of tetralogy of Fallot: retrospective cohort study by Tugba Erdil, Klaus Steigmiller, John Ethan Rampa, Martin Christmann, Ulrike Held, Hitendu Dave

“…This retrospective study aimed to analyse factors affecting contemporary long-term outcomes with a focus on pulmonary annular growth and function over time. METHODS: 131 consecutive isolated tetralogy of Fallot repairs performed between 2004 and 2014 at University Children’s Hospital Zurich were included. …”
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Rationale and Design of the ORCCA (Outcomes Registry for Cardiac Conditions in Athletes) Study by Nathaniel Moulson, Bradley J. Petek, Michael J. Ackerman, Timothy W. Churchill, Sharlene M. Day, Jonathan H. Kim, Stephanie A. Kliethermes, Rachel Lampert, Benjamin D. Levine, Matthew W. Martinez, Manesh R. Patel, Dermot Phelan, Kimberly G. Harmon, Aaron L. Baggish, Jonathan A. Drezner

“…Recent guidelines have taken a more permissive approach, using a shared decision‐making model. …”
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Long-Term Nonprogression Is a Form of Response to Cardiac Resynchronization Therapy by Sander Trenson, MD, PhD, Peter C. Kahr, MD, Bert Vandenberk, MD, PhD, Matthias Schindler, PhD, Alexander Breitenstein, MD, Ardan M. Saguner, MD, Andreas J. Flammer, MD, Frank Ruschitzka, MD, Firat Duru, MD, Jan Steffel, MD, Stephan H. Winnik, MD, PhD

“…After a mean follow-up of another 57 months, progressors were significantly more likely to reach the composite endpoint of death, ventricular assist device implantation, or heart transplantation compared to nonprogressors (adjusted HR: 2.26 [95% CI: 1.35-3.78]; P = 0.002). …”
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Impact of Left Ventricular Diastolic Pressure Changes on Clinical Outcomes After Transcatheter Aortic Valve Replacement by Jiwon Seo, Ah‐Ram Kim, Iksung Cho, Chi Young Shim, Geu‐Ru Hong, Eui‐Young Choi, Se‐Joong Rim, Young‐Guk Ko, Myeong‐Ki Hong, Jae‐Kwan Song, Jong‐Won Ha

“…The primary outcome was a composite of all‐cause death and rehospitalization for heart failure. …”
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Use of Population-Based Compartmental Modeling and Retinol Isotope Dilution to Study Vitamin A Kinetics and Total Body Stores among Ghanaian Women of Reproductive Age by Michael H Green, Veronica Lopez-Teros, Joanne Balmer Green, Georg Lietz, Sika M Kumordzie, Anthony Oxley, Ahmed D Fuseini, K Winifred Nyaaba, Emily Becher, Jennie N Davis, K Ryan Wessells, Seth Adu-Afarwuah, Reina Engle-Stone, Marjorie J Haskell

“…Composite data (plasma retinol fraction of dose; FDp) were analyzed using Simulation, Analysis and Modeling software to obtain kinetic parameters, TBS, and other state variables as well as model-derived values for the RID composite coefficient FaS. …”
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Protocol for a multicentre, randomised, parallel-control, superiority trial comparing administration of clotting factor concentrates with a standard massive haemorrhage protocol in... by Neil Parry, Andrew Beckett, Jo Carroll, Homer Tien, Jeannie Callum, Andrew Petrosoniak, Damon Scales, Luis Teodoro da Luz, Keyvan Karkouti, Paul T Engels, Hans-Peter Hucke, Deep Grewal, Bruce Schwartz, Henry Peng

“…However, there is a knowledge gap on their use compared with the standard of care, the transfusion of plasma.Methods and analysis The factors in the initial resuscitation of severe trauma 2 trial is a multicentre, randomised, parallel-control, single-blinded, phase IV superiority trial. …”
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Association of body mass index and outcomes in surgical and transcatheter aortic valve replacement by Bennet S. Cho, MD, Troy N. Coaston, BS, Amulya Vadlakonda, BS, Sara Sakowitz, MPH, MS, Syed Shaheer Ali, Esteban Aguayo, MD, Peyman Benharash, MD

“…This study assessed the nuanced relationship between BMI and clinical outcomes in a nationally representative cohort undergoing aortic valve replacement. Methods: Adult (≥18 years) admissions for elective SAVR or TAVR from the 2016–2021 National Inpatient Sample were analyzed. …”
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The perceived workload of first-line healthcare professionals during neonatal resuscitation by Hai-Bo Huang, Kui Sang, Ming Zhou, Lin Yi, Jiang-Qin Liu, Chuan-Zhong Yang, Brenda H.Y. Law, Georg M. Schmölzer, Po-Yin Cheung

“…We aimed to characterize and compare the perceived workload between MDs and nurses/midwives who provided neonatal resuscitation. Methods: In a prospectively designed, cellphone-based surveillance, perceived workload and stress of MDs and nurses/midwives during neonatal resuscitation was evaluated using a modified multi-dimensional NASA-TLX survey in three tertiary Neonatal Intensive Care Units in China. …”
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Sex differences in the prevalence and survival of pulmonary hypertension in obstructive hypertrophic cardiomyopathy following septal myectomy by Changrong Nie, Yifeng Zhu, Minghu Xiao, Changsheng Zhu, Yanhai Meng, Zhengyang Lu, Qiulan Yang, Shuiyun Wang

“…Herein, we investigated sex differences in the prevalence and survival of pH in oHCM following septal myectomy. Methods: We consecutively enrolled 1491 patients diagnosed with oHCM. …”
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A Review of Multidisciplinary Evidence on the Role of Urban Green Space in Improving the Sleep Quality of the Elderly by Ning KANG, Han XIE, Tao JIANG

“…The elderly with genetically susceptible gut microbiota may experience distinct sleep improvement effects from green spaces compared to those with more stable gut microbiota compositions. Additionally, culturally-specific lifestyle patterns and attitudes toward nature may lead to variations in sleep improvement outcomes among the elderly from diverse cultural backgrounds when they use green spaces.ConclusionResearch on improving sleep health of the elderly must transcend single-discipline limitations, integrating theories and research methods from multiple fields including geriatrics and gerontology, neuroscience and neurology, psychiatry, psychology, behavioral science, sociology, rehabilitation medicine, exercise science, and environmental science and ecology. …”
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Outpatient acute kidney disease detection by national and institutional health data by Hsiu-Yin Chiang, Hung-Chieh Yeh, Zi-Han Lin, Bradley Chen, David Ray Chang, I-Wen Ting, Jie-Sian Wang, Yun-Lun Chang, Hung-Lin Chen, Yu-Chih Liu, Mei-Chuan Hsieh, Tzu-Ling Karen Tzeng, Chin-Chi Kuo

“…In this retrospective cohort study, the associations between AKDOPT and composite kidney outcome (CKO; e.g., end-stage kidney disease, a >40% drop in estimated glomerular filtration rate, or a 2-fold or more increase in serum creatinine), all-cause mortality, and de novo non-dialysis chronic kidney disease (CKD-ND) were evaluated using multivariable Cox proportional hazards models. …”
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Analysis of microstructure properties of Ni-Fe MOFs and their influence on selective recognition of single and binary dye systems by Dan Xu, Xiaolin Cao, Jie Zhou, Zhihao Lin, Jing Wang, Jiatong Han, Ge Chen, Guangyang Liu, Xiaomin Xu, Yanguo Zhang, Donghui Xu

“…In this study, five types of Ni/Fe-MOFs were synthesized via a one-pot solvothermal method by varying the Ni/Fe molar ratio. Their physicochemical structures, surface morphologies, and compositions were characterized through a series of techniques, and their adsorption performances for different dyes were preliminarily investigated. …”
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Dental Students’ Perception and Self-Perceived Confidence Level in Key Dental Procedures for General Practice and the Impact of Competency Implementation on Their Confidence Level,... by Wijdan R. Elmanaseer, Salah A. Al-Omoush, Rasha A. Alamoush, Rawan Abu Zaghlan, Firas Alsoleihat

“…The same applies to 6 out of 16 conservative dentistry procedures: placing anterior composite (4.41 vs. 4.12), placing posterior composite (4.43 vs. 3.88), placing posterior amalgam (4.29 vs. 4.02), placing matrix band for Class II restorations (4.24 vs. 3.71), placing a prefabricated post (3.34 vs. 2.88), and placing fiber post (3.45 vs. 3.34). …”
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Impact of antihypertensive drug classes on cardiovascular outcomes: insights from the STEP study by Xinyi Peng, Michael Hecht Olsen, Manan Pareek, Jingjing Bai, Yang Liu, Qirui Song, Jun Cai

“…Conclusions This post hoc analysis suggested that ARBs and CCBs might be more favourable for composite cardiovascular outcomes than diuretics and beta-blockers. …”
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Obstructive sleep apnea syndrome in polycystic ovary syndrome: a systematic review and meta-analysis by Nur K. Abdul Jafar, Afra Al Balushi, Anuradhaa Subramanian, Siang Ing Lee, Christie J. Bennett, Lisa J. Moran, Aya Mousa, Chau Thien Tay, Helena J. Teede, Darren R. Mansfield

“…Compared with non-PCOS, those with PCOS showed higher risk for composite OSA (odds ratio (OR): 9.52; 95% CI: 3.90 to 23.26; I2 = 54.5%; 8 studies, n=942; P<0.001) and more pronounced OSAS risk with increasing symptom severity in PCOS (AHI≥5 OR: 3.90; 95% CI: 1.63 to 9.34; AHI≥5 with symptoms OR: 17.95; 95% CI: 6.17 to 52.22; AHI≥10 with symptoms OR: 30.61; 95% CI: 7.99 to 117.25, all P ≤ 0.0023). …”
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Relationship between cognitive impairments and psychopathological symptoms in female schizophrenia subsequent to 8 weeks treatment with antipsychotic drugs by Shuzhan Gao, Qing Xu, Yanlin Han, Jing Jiang, Fan Wu, Ting Peng, Chenxi Ling, Sulin Ni, Rongrong Zhang, Yidan Ming, Xuzhen Liu, Xijia Xu

“…Further exploration of the characteristics of female schizophrenia patients can offer valuable sex-related considerations for clinicians in diagnosis and interventions. Methods Our study involved 94 female patients with drug-naïve or drug-withdrawal schizophrenia who received antipsychotic drug for 8 weeks, along with 71 age-matched female healthy controls. …”
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Exopolysaccharide (EPS) Production by Endophytic and Basidiomycete Fungi by Wai Prathumpai, Umpawa Pinruan, Sujinda Sommai, Somjit Komwijit, Kwanruthai Malairuang

“…The selected fungal isolate of <i>S. commune</i> LF01962 was used for further optimization of different medium compositions affecting exopolysaccharide production using statistical methods. …”
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Changes in unhealthy food consumption among vulnerable elementary-aged children in the United States during the COVID-19 pandemic: a serial cross-sectional analysis by Nivedhitha Parthasarathy, Nalini Ranjit, Ru-Jye Chuang, Christine Markham, Mike Pomeroy, Jacqueline Noyola, Deepali K. Ernest, Shreela V. Sharma

“…ObjectiveSeveral studies suggest that during the early pandemic, amidst socioeconomic instability, children from underserved families were more likely to resort to consuming cheaper, lower-quality foods with longer shelf lives. …”
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The effect of α-lipoic acid treatment on plasma asymmetric dimethylarginine, a biomarker of endothelial dysfunction in diabetic neuropathy by Ferenc Sztanek, Hajnalka Lőrincz, Ágnes Molnár, Anita Szentpéteri, Eszter Zöld, Ildikó Seres, Dénes Páll, Mariann Harangi, Péter Kempler, György Paragh

“…The change in ADMA level was more pronounced in responder patients based on both CPT and CAS. …”
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Comparative assessment of line probe assays and targeted next-generation sequencing in drug-resistant tuberculosis diagnosisResearch in context by Giovanna Carpi, Marva Seifert, Andres De la Rossa, Swapna Uplekar, Camilla Rodrigues, Nestani Tukvadze, Shaheed V. Omar, Anita Suresh, Timothy C. Rodwell, Rebecca E. Colman

“…Comparative evaluations of molecular diagnostic assays in high-burden settings are essential for informing clinical decision-making for DR-TB treatment. Methods: The Seq&Treat clinical study previously evaluated the performance of two targeted next-generation sequencing (tNGS) workflows, GenoScreen Deeplex Myc-TB and Oxford Nanopore Technologies Tuberculosis Drug Resistance Test, on direct sediment samples from persons at risk for DR-TB. …”
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