Exploring Two Modified Ali-Mikhail-Haq Copulas and New Bivariate Logistic Distributions by Christophe Chesneau

“…The second copula offers another modeling option; it is exchangeable like the Ali-Mikhail-Haq copula, but it benefits from a broader range of negative dependence correlations and more adaptable tail dependence properties. For the two proposed copulas, we investigate their main characteristics, including quadrant dependence, copula density function, conditional copulas, couples of value generation, extended variants via standard copula schemes, comprehensive copula orders, and weighted harmonic mean copula transformations. …”
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A novel approach on laplacian energy of -dominating complex spherical fuzzy graph structures and with application by S. N. Suber Bathusha, S. Angelin Kavitha Raj, Mufti Mahamud, Sowndharya Jayakumar

“…Due to its coverage in three directions: complex membership functions, complex abstinence membership function, and complex non-membership functions, CSFS has more flexibility than CFSs, CIFSs, CPFSs, and CPicFS. …”
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The vascular endothelium as decision maker in lung injury by Diana Klein

“…When the endothelium fails to perform these functions adequately, leading to endothelial dysfunction, pathological conditions are more likely to develop. …”
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Microbial metabolism in laboratory reared marine snow as revealed by a multi-omics approach by Lei Hou, Zihao Zhao, Barbara Steger-Mähnert, Nianzhi Jiao, Gerhard J. Herndl, Yao Zhang

“…Abstract Background Marine snow represents an organic matter-rich habitat and provides substrates for diverse microbial populations in the marine ecosystem. However, the functional diversity and metabolic interactions within the microbial community inhabiting marine snow remain largely underexplored, particularly for specific metabolic pathways involved in marine snow degradation. …”
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Clinical implications, safety, efficacy of Recombinant Human Granulocyte Colony-Stimulating Factors and Pegylated Equivalent by Silvia Bolis, Emilia Cocorocchio, Consuelo Corti, Andrés J M Ferreri, Niccolò Frungillo, Giovanni Grillo, Emanuela Salè Omodeo, Lucilla Tedeschi, Vittorio Ruggero Zilioli

“…For instance, lenograstim binds to receptors in the same way of endogenous ligand, and neutrophils obtained from stimulation with this G-CSF have a physiological activity profile similar to neutrophils normally generated in humans. Conversely, the different interaction between filgrastim and G-CSF receptor is more frequently associated with morphological abnormalities, reduced motility and chemotaxis and a reduced response to bacterial stimuli in induced neutrophils.…”
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The extracellular loop 2 (ECL2) of the human histamine H4 receptor substantially contributes to ligand binding and constitutive activity. by David Wifling, Günther Bernhardt, Stefan Dove, Armin Buschauer

“…To study the role of the FF motif in ECL2, we generated the hH4R-F168A mutant. The receptor was co-expressed in Sf9 insect cells with the G-protein subunits Gαi2 and Gβ1γ2, and the membranes were studied in [3H]histamine binding and functional [35S]GTPγS assays. …”
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A comparative survey of the influence of small self-cleaving ribozymes on gene expression in human cell culture by Dennis Kläge, Elisabeth Müller, Jörg S. Hartig

“…We were able to identify functional structures suited for aptazyme design and generated highly efficient hammerhead ribozyme variants originating from the human genome. …”
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Phenotypic mutation rates and the abundance of abnormal proteins in yeast. by Martin Willensdorfer, Reinhard Bürger, Martin A Nowak

“…In our model, genes are regulated to synthesize a certain number of functional proteins. During this process, depending on the phenotypic mutation rate, abnormal proteins are generated. …”
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Vibroacoustic monitoring of bearing points failures in the driving system of the mining main ventilation fans by T. ZAKRZEWSKI

“…Here, such diagnosis estimates were selected that their values determined at the moment of checking, allowed to draw conclusions on the functional characteristics of the bearing points.…”
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Early manifestations of replicative aging in the yeast Saccharomyces cerevisiae by Maksim I. Sorokin, Dmitry A. Knorre, Fedor F. Severin

“…Looking into the mechanism, we found that knockouts of genes responsible for mitochondriato-nucleus (retrograde) signaling, RTG1 or RTG3, significantly decrease the resistance of cells that generated more than four daughters, but not of the younger ones. …”
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Adopting activated carbons on the PET depolymerization for purifying r-TPA by Cho Woo Seok, Lee Joon Hyuk, Na Da Yun, Choi Sang Sun

“…Furthermore, the r-TPA exhibited comparable thermal properties and functional groups to virgin terephthalic acid, demonstrating that the purification process did not compromise its inherent characteristics. …”
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Design of smart agriculture based on big data and Internet of things by Chunling Li, Ben Niu

“…The algorithm in this article can realize the functions of real-time data communication and information processing more efficiently, and has a significant role in promoting agricultural informatization and improving the level of agricultural modernization.…”
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DEVELOPMENT OF AN AUTOMATED FLUORESCENCE MICROSCOPY ASSAY FOR QUANTIFYING FACTORS AFFECTING RED BLOOD CELL (RBC) SICKLING IN SICKLE CELL DISEASE (SCD) by ML Arrojo, ACS Pinto, SK Haddad, RA Panepucci

“…However, the lack of straightforward functional assays to quantitate how these factor affect cell sickling, hamper a more profound understanding of SCD physiopathology. …”
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Study on Conventional and Rheological Properties of Corn Stalk Bioasphalt/PPA Composite Modified Asphalt by Fuhai Wang, Tuo Huang, Gongfeng Xin, Minghao Mu, Quanjun Shen

“…The bioasphalt did not affect the chemical structure of asphalt. However, PPA generated new functional groups (P-O single bond, phosphate (RO)3P = O, and P=O double bond) causing a chemical modification in the asphalt binder. …”
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Highly Uniform White Light-Based Visible Light Communication Using Red, Green, and Blue Laser Diodes by Jie Yang, Zhe Liu, Bin Xue, Zhou Liao, Liangsen Feng, Ning Zhang, Junxi Wang, Jinmin Li

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Xuebijing alleviates high-voltage electrical burn-induced acute kidney injury by inhibiting neutrophils and inflammation by Xiaopei He, Na Li, Leilei Ma, Meng Yang, Liqing Ren, Jiawen Hao, Xin Xue, Yinghui Pang

“…While it improves kidney function and reduces inflammation, its effects on SOD and MDA levels suggest a complex interaction with the oxidative stress system that requires further investigation, as the observed changes in these markers (decreased SOD, increased MDA) in the Xuebijing group were more pronounced than in the control group. …”
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The SARS-CoV-2 main protease causes mitochondrial dysfunction in a yeast model by Wojciech Grabiński, Anna Kicińska, Karolina Funtowicz, Tomasz Skrzypczak, Andonis Karachitos

“…Abstract Saccharomyces cerevisiae has proven to be an invaluable model organism for studying mitochondrial function owing to its genetic tractability and the high conservation of mitochondrial processes among eukaryotes, including humans. …”
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Real-Time, Risk-Based Clinical Trial Quality Management in China: Development of a Digital Monitoring Platform by Min Jiang, Shuhua Zhao, Yun Mei, Zhiying Fu, Yannan Yuan, Jie Ai, Yuan Sheng, Ying Gong, Jingjing Chen

“…The warning thresholds were applied to 211 QC reports generated in 2023, of which 19.9% (n=42) triggered warnings. …”
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CO40 | The co-inheritance of two ITGB3 variants exerting additive detrimental effects on platelets leads to variant Glanzmann thrombasthenia

“…When both variants were co-expressed, the combined defect was more severe, with further reduced receptor surface expression and significantly impaired cell functions. …”
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Tremor and its duration‐amplitude distribution at Popocatépetl volcano, Mexico by R. Arámbula‐Mendoza, C. Valdés‐González, N. Varley, T. A. Reyes‐Pimentel, B. Juárez‐García

“…Abstract The duration‐amplitude distribution was calculated for the tremor observed at Popocatépetl volcano during episodes of activity in 2000 and 2012–2014. An exponential function was used to obtain a good fit for the duration‐amplitude distribution, and the source of volcanic tremor is probably generated by the transportation of magmatic fluids and its coupling with the host rock within the volcanic conduit. …”
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