T cell epitope mapping reveals immunodominance of evolutionarily conserved regions within SARS-CoV-2 proteome by Cansu Cimen Bozkus, Matthew Brown, Leandra Velazquez, Marcus Thomas, Eric A. Wilson, Timothy O’Donnell, Anna Kaminska, Denis Ruchnewitz, Douglas Geertz, Yonina Bykov, Julia Kodysh, Kasopefoluwa Y. Oguntuyo, Vladimir Roudko, David Hoyos, Komal D. Srivastava, Giulio Kleiner, Hala Alshammary, Neha Karekar, Christopher McClain, Ramya Gopal, Kai Nie, Diane Del Valle, Daniela Delbeau-Zagelbaum, Denise Rodriguez, Jessica Setal, Emily Carroll, Margrit Wiesendanger, Percio S. Gulko, Alexander Charney, Miriam Merad, Seunghee Kim-Schulze, Benhur Lee, Ania Wajnberg, Viviana Simon, Benjamin D. Greenbaum, Diego Chowell, Nicolas Vabret, Marta Luksza, Nina Bhardwaj

“…Collectively, these findings identify immunodominant T cell epitopes across the SARS-CoV-2 proteome that may enhance immune surveillance against emerging variants and inform next-generation vaccine designs providing broader and more durable protection.…”
Get full text

Climate and aging. Selected aspects from the psychological perspective by Henryk Olszewski

“…I wrote an article about climate change and its relationship to the psychological functioning of people in old age. As we enter adulthood, the new generation will severely experience increasingly extreme weather events. …”
Get full text

Grid-Based Hole Recovery Mechanism Using Virtual Force in Hybrid WSNs by Kuo-Feng Huang, Shih-Jung Wu

“…Sensor nodes are typically empowered with scarce energy resources and limited computing functionality in wireless sensor networks. However, nonuniform random deployment, depletion, and failure of sensor nodes will lead to generating coverage hole in the entire network. …”
Get full text

Integrated Reporting: Problems of Formation by N. A. Mislavskaya

“…The latter are interesting in the symbiosis of criticism and constructivism because against the lack of objective reasons for the introduction of integrated reporting in Russia, there are questions raised about the need to generate a unified theory that underlies the functioning of accounting systems as well as the economic consciousness development of our society and implementation of business ethics. …”
Get full text

Research on a Service Touchpoint Design Model Driven by Smart Technology Based on Kano–Failure Modes and Effects Analysis by Jian Chen, Zhihan Li, Weiwei Wang, Yi Wang, Zhaoxuan He

“…The Kano model is employed in the user requirement identification phase to provide more precise user requirement parameters, while FMEA is employed in the failure risk analysis phase to generate more accurate failure risk assessments. …”
Get full text

Association mapping of lignin response to Verticillium wilt through an eight-way MAGIC population in Upland cotton by Xiao-min TIAN, Peng HAN, Jing WANG, Pan-xia SHAO, Qiu-shuang AN, Nurimanguli AINI, Qing-yong YANG, Chun-yuan YOU, Hai-rong LIN, Long-fu ZHU, Zhen-yuan PAN, Xin-hui NIE

“…Three stable quantitative trait loci (QTLs), qLRVW-A04, qLRVW-A10, and qLRVW-D05, were identified in more than two environments. Two key candidate genes, Ghi_D05G01046 and Ghi_D05G01221, were selected within the QTLs through the combination of variations in the coding sequence, induced expression patterns, and function annotations. …”
Get full text

Effects of Land Fragmentation on Productivity in Northwestern Ethiopia by Gashaw Tenna Alemu, Zewdu Berhanie Ayele, Assefa Abelieneh Berhanu

“…Hence, the government should come up with land use policy and population growth controlling program, which enables determining minimum economic farmland size, improving land productivity, and finding ways to strengthen off-farm activities and livestock sector to absorb more labor and enhance means of generating more income so as to decrease minimum farmland size required.…”
Get full text

Improved multi-objective decision-making in manufacturing processes through uncertainty quantification and robust pareto front modelling by Arne De Temmerman, Mathias Verbeke

“…We investigate the impact of aleatoric uncertainty on multi-objective optimization, demonstrating enhanced Pareto front creation and improved decision-making under non-linear process functions. The methodology is applied to a continuous manufacturing case, where probabilistic surrogate sampling generates a more conservative setpoint. …”
Get full text

Sustainability and Resilience in the Rehabilitation of Road Infrastructures After an Extreme Event: An Integrated Approach by Marinella Giunta

“…For road infrastructures, the concepts of sustainability and resilience are becoming more and more relevant. The sustainability is closely linked with the concept of development that meets the needs of the present without compromising the ability of future generations to meet their own needs. …”
Get full text

The Impact of Government Subsidies on Income Inequality Among Farm Households in China: Evidence from CFPS Panel Data by Leyi Wang, Li Deng, Shi Zheng

“…Our study found that the following results: (1) The mechanism of subsidy action combines the functions of increasing income and regulating income distribution. …”
Get full text

MicroRNA-665 and its potential role in drug response and survival outcomes in multiple myeloma: a preliminary study by Rui Bergantim, Rui Bergantim, Rui Bergantim, Rui Bergantim, Sara Peixoto da Silva, Sara Peixoto da Silva, Sara Peixoto da Silva, Vanessa Pinto, Vanessa Pinto, Joana M. Pereira, Joana M. Pereira, Diana Sousa, Diana Sousa, Diana Sousa, Fernanda Trigo, Rune Matthiesen, José E. Guimarães, José E. Guimarães, José E. Guimarães, José E. Guimarães, José E. Guimarães, M. Helena Vasconcelos, M. Helena Vasconcelos, M. Helena Vasconcelos

“…In silico analysis for target-prediction and gene ontology (GO) enrichment was performed to explore the potential biological and functional role of the identified miRNAs.ResultsNGS profiling revealed several miRNAs differently expressed between treatment-refractory and sensitive patients, as well as between PB and BM. …”
Get full text

Partial depletion of circulating neutrophil granulocytes in mice exacerbates the inflammatory response and hypothermia during LPS induced severe systemic inflammation by Jessica Hernandez, Fabian Johannes Pflieger, Julia Schäffer, Leona Bähr, Jenny Schneiders, Thomas Reichel, Marita Meurer, Marita Meurer, Benjamin Lamp, Natali Bettina Bauer, Karsten Krüger, Lois Harden, Maren von Köckritz-Blickwede, Maren von Köckritz-Blickwede, Christoph Rummel, Christoph Rummel, Christoph Rummel

Get full text

The Great Disruption: How Machine Intelligence Will Transform the Role of Lawyers in the Delivery of Legal Services by J. O. Mcginnis, R. G. Pearce

“…Eventually, machine intelligence will prove faster and more efficient than many lawyers in providing those services. …”
Get full text

Smart CAR-T Nanosymbionts: archetypes and proto-models by Juan C. Baena, Juan C. Baena, Juan Sebastián Victoria, Juan Sebastián Victoria, Alejandro Toro-Pedroza, Alejandro Toro-Pedroza, Cristian C. Aragón, Cristian C. Aragón, Joshua Ortiz-Guzman, Joshua Ortiz-Guzman, Joshua Ortiz-Guzman, Juan Esteban Garcia-Robledo, Juan Esteban Garcia-Robledo, David Torres, Lady J. Rios-Serna, Lady J. Rios-Serna, Ludwig Albornoz, Joaquin D. Rosales, Joaquin D. Rosales, Carlos A. Cañas, Carlos A. Cañas, Carlos A. Cañas, Gustavo Adolfo Cruz-Suarez, Gustavo Adolfo Cruz-Suarez, Gustavo Adolfo Cruz-Suarez, Gustavo Adolfo Cruz-Suarez, Felipe Ocampo Osorio, Felipe Ocampo Osorio, Felipe Ocampo Osorio, Tania Fleitas, Ivan Laponogov, Alexandre Loukanov, Alexandre Loukanov, Alexandre Loukanov, Kirill Veselkov, Kirill Veselkov

“…Engineered nanoparticles can improve gene delivery, target tumors more precisely, enhance immune cell function, and enable in vivo CAR-T production, reducing the need for labor-intensive ex vivo processes. …”
Get full text

RENEWABLES IN DEVELOPMENT OF THE ARAB EAST (CASE OF SOLAR ENERGY) by A. O. Filonik, V. A. Isaev, V. M. Morozov

“…Insufficient experience and lack of competence are followed by more serious factors seeing in bureaucratic hurdles, passivity of national capital, incorrect distribution of functions among administrative bodies, etc. …”
Get full text

The potential of Logistics 4.0 technologies: a case study through business intelligence framing by applying the Delphi method by Joaquim Jorge Vicente, Joaquim Jorge Vicente, Lurdes Neves, Inês Bernardo

“…IntroductionThe growing competitiveness and the importance of data availability for organizations have created a demand for intelligent information systems capable of analyzing data to support strategy and decision-making. Organizations are generating more and more data due to new technologies associated with Industry 4.0 and Logistics 4.0, making it essential to transform this data into relevant information to streamline decision-making processes. …”
Get full text

IGF2BP2 binding to CPSF6 facilitates m6A‐mediated alternative polyadenylation of PUM2 and promotes malignant progression in ovarian cancer by Xin Luo, Qinglv Wei, Lingcui Xie, Ningxuan Chen, Bin Gu, Jiani Xu, Xiaoyan Jiang, Xinzhao Zuo, Hongyan Zhao, Xiaoyi Liu, Yu Yang, Tao Liu, Yong Zhu, Ping Yi, Jing Xu

“…PUM2 was carried m6A and recognized by IGF2BP2, and CPSF6 was recruited at the proximal polyadenylation signal (pPAS) to generate the short‐3′UTR transcript. The short PUM2 transcript was more stable than the long transcript, which promoted the malignant progression of OC. …”
Get full text

Interpréter dans la grosseur du trait by François-Joseph Daniel

“…On the other hand, when the models are used to evaluate the nuisance, in the context of an already established and functioning facility, the discrepancies between the model results and the local residents’ experiential perceptions create a need for model validation in context. …”
Get full text

Polishing inner wall of crossed deep micropores using magnetic microabrasive jet technology by Zezhi WANG, Jie WANG, Xiaogang MA, Fan LI, Xinya FAN, Yan CHEN

“…In view of the problems of conventional finishing processing of cross deep micro-holes being limited by size, uneven processing, and poor quality, and combined with the characteristics of a stable removal function and strong adaptability of the abrasive jet, the magnetic micro-abrasive jet technology finishing processing method is proposed to improve the quality of the inner wall of cross deep micro-holes.MethodsAn independent magnetic abrasive jet device was used to carry out finishing tests on the cross deep micro-holes, and an electromagnetic device was used to generate a focusing magnetic force near the nozzle outlet. …”
Get full text

Assessment of Thermodynamic Efficiency of the Belarusian Energy System. Part 2 by V. N. Romaniuk, A. A. Bobich, T. V. Ryzhova, T. V. Bubyr, V. V. Yanchuk, Y. S. Yatsukhna

“…More than half of the annual consumption of thermal energy in Belarus is accounted for by heat-generating sources, while thermal power plants provide up to 88 % of heat output. …”
Get full text