A High-Throughput, Three-Dimensional Multiple Myeloma Model Recapitulating Tumor-Stroma Interactions for CAR-Immune Cell-Mediated Cytotoxicity Assay by Luanpitpong S, Janan M, Poohadsuan J, Rodboon N, Samart P, Rungarunlert S, Issaragrisil S

“…Through this assay, we demonstrated that CAF-like stromal cells impaired NK cell effector function in 2D culture and 3D spheroids, likely via paracrine signaling and physical barrier function. …”
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Stimulus representation in human frontal cortex supports flexible control in working memory by Zhujun Shao, Mengya Zhang, Qing Yu

“…Here, we tested the hypothesis that stimulus representation persists in the frontal cortex to facilitate flexible control demands in WM. During functional MRI, participants flexibly switched between simple WM maintenance of visual stimulus or more complex rule-based categorization of maintained stimulus on a trial-by-trial basis. …”
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Autophagic flux-lipid droplet biogenesis cascade sustains mitochondrial fitness in colorectal cancer cells adapted to acidosis by Xiaojie Liu, Xue Sun, Wenqing Mu, Yanan Li, Wenqing Bu, Tingting Yang, Jia Zhang, Rui Liu, Jiayu Ren, Jin Zhou, Peishan Li, Yufang Shi, Changshun Shao

“…Here, we show that colorectal cancer cells adapted to acidic microenvironment (CRC-AA) are more reliant on oxidative phosphorylation than their parental cells, and the acetyl-CoA in CRC-AA cells are generated from fatty acids and glutamine, but not from glucose. …”
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IMDM-20 enhances neutrophilic features during 1.3 % DMSO-mediated differentiation of HL-60 cells by Jorge Andrés Cázares-Preciado, José Antonio Cruz-Cárdenas, Alejandra López-Arredondo, Marco V. Gallardo-Camarena, Marion E.G. Brunck

“…Multiple differentiation protocols have been reported to generate neutrophil-like HL-60 cells, with limited consideration of how methodological variations might influence cell identity and functions. …”
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Analysis of the VIT1 Promoter Activity in Developing Arabidopsis thaliana Plants by Seckin Eroglu

“…Iron (Fe) deficiency in plants is one of the widespread problems limiting agricultural production. Generating crops more tolerant to Fe deficiency by genetic engineering or breeding is of great interest but challenging due to the knowledge gaps in general plant Fe homeostasis. …”
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The study of synchronization accuracy of ENMU devices according to the PTPv2 protocol in laboratory conditions by Yu. G. Kononov, P. A. Zvada, E. G. Zelenskii, R. A. Zvezdilin, D. A. Turchenko

“…The study was performed in laboratory conditions using a time correction unit, an industrial switchboard and a media converter, a bay with an 8 km long OKP-K-8 fiber-optic cable, a reference signal generator and a backup measuring system based on National Instruments measuring devices implementing the PMU functionality.Results and discussion. …”
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De l’obsolescence dans la médiation by Véronique Dagues

“…But if “the learner is thought of as a social actor with his own personal identity and learning a form of social mediation” (Dictionary of French didactic as foreign and second Language), one would neither be able to reduce the learner to a function nor assign the learner to the role of an actor without denying what the learner is above all else: a subject, capable of speech (Anderson).Is language reducible to a sort of machinery of which it is a question of learning the manipulations, uses, modes, and functions; a tool for knowing how to say, do and be and learn for learning’s sake, a form of transport, a vehicle-language? …”
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Ultrastructural changes in the common carotid artery in terms of age and gender-related in Rat model by Nejat Ünlükal

“…Although the pathologies observed in the vessels are commonly attributed to the generation of atheromas, it has been recognised in recent years that changes in the tunica intima and tunica media lead to impaired vascular function without the formation of atheromas. …”
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A machine-learning approach for predicting butyrate production by microbial consortia using metabolic network information by Claudia Silva-Andrade, Sergio Hernández, Pedro Saa, Ernesto Perez-Rueda, Daniel Garrido, Alberto J. Martin

“…Despite its importance, there is a lack of computational methods capable of predicting its production as a function of the consortium composition. Here, we present a novel machine-learning approach leveraging automatically generated genome-scale metabolic models to tackle this limitation. …”
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ScreenSafeFuture: A parent-empathetic and pragmatic mhealth application for toddlers' brain development addressing screen-addiction challenges by Nafisa Anjum, Md. Mehedi Hasan, Syeda Umme Salma, Liang Zhao, Maria Valero de Clemente, Nazmus Sakib

“…These development phases will utilize the Delphi panel consensus for a more reliable and robust outcome, ensuring its effectiveness in addressing screen addiction challenges and supporting younger generations' healthy development.…”
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Integrating patient metadata and pathogen genomic data: advancing pandemic preparedness with a multi-parametric simulator by Bonjean Maxime, Ambroise Jérôme, Orchard Francisco, Sentis Alexis, Hurel Julie, Hayes Jessica S., Connolly Máire A., Jean-Luc Gala

“…Abstract Stakeholder training is essential for handling unexpected crises swiftly, safely, and effectively. Functional and tabletop exercises simulate potential public health crises using complex scenarios with realistic data. …”
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Precipitation–Flotation Process for Molybdenum and Uranium Separation from Wastewater by Yanfang Huang, Sa Yue, Aohua Li, Hu Sun, Yizhuang Wang, Qunzhen Bu, Bingbing Liu, Guihong Han

“…The mining of molybdenum and uranium ores inevitably results in the generation of large volumes of wastewater containing low concentrations of metals, which poses significant threats to the environment. …”
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Multi-fusion strategy network-guided cancer subtypes discovering based on multi-omics data by Jian Liu, Xinzheng Xue, Pengbo Wen, Qian Song, Jun Yao, Shuguang Ge

“…IntroductionThe combination of next-generation sequencing technology and Cancer Genome Atlas (TCGA) data provides unprecedented opportunities for the discovery of cancer subtypes. …”
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Looking into New Sources of Bioactives: Seasonal Variation in Bioactive Compounds and Dietary Fiber of Agave Bagasse from Mezcal Production by Jimena Álvarez-Chávez, Elisa Dufoo-Hurtado, Liliana Santos-Zea, Aurea K. Ramírez-Jiménez

“…Some studies have begun to demonstrate that agave bagasse has the potential to be recycled as a source of functional ingredients due to its dietary fiber and bioactive compound content. …”
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Development and Analysis of a Non-Resonant Wide-Band Tri-Axial Electromagnetic Energy Harvester by Hamid Khan, Farid Ullah Khan

“…Additionally, experimental results show that the developed harvester can generate much more power than single-coil energy harvesters. …”
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Elevating larval source management as a key strategy for controlling malaria and other vector-borne diseases in Africa by Fredros Okumu, Sarah J. Moore, Prashanth Selvaraj, Arnon Houri Yafin, Elijah O. Juma, GloriaSalome G. Shirima, Silas Majambere, Andy Hardy, Bart G. J. Knols, Betwel J. Msugupakulya, Marceline Finda, Najat Kahamba, Edward Thomsen, Ayman Ahmed, Sarah Zohdy, Prosper Chaki, Peter DeChant, Kimberly Fornace, Nicodem Govella, Steven Gowelo, Emmanuel Hakizimana, Busiku Hamainza, Jasper N. Ijumba, William Jany, Hmooda Toto Kafy, Emmanuel W. Kaindoa, Lenson Kariuki, Samson Kiware, Eliningaya J. Kweka, Neil F. Lobo, Dulcisária Marrenjo, Damaris Matoke-Muhia, Charles Mbogo, Robert S. McCann, April Monroe, Bryson Alberto Ndenga, Halfan S. Ngowo, Eric Ochomo, Mercy Opiyo, Richard Reithinger, Chadwick Haadezu Sikaala, Allison Tatarsky, David Takudzwa, Fedra Trujillano, Ellie Sherrard-Smith

“…In this paper, we argue that the heavy reliance on large-scale cluster-randomized controlled trials (CRTs) to generate evidence on epidemiological endpoints restricts the recommendation of approaches to only those interventions that can be measured by functional units and deliver relatively uniform impact and, therefore, are more likely to receive financial support for conducting these trials. …”
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A Comparative Crash-Test of Manual and Semi-Automated Methods for Detecting Complex Submarine Morphologies by Vasiliki Lioupa, Panagiotis Karsiotis, Riccardo Arosio, Thomas Hasiotis, Andrew J. Wheeler

“…The analysis reveals that the semi-automated methods provided more efficient results in comparison with the time-consuming manual mapping. …”
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Optimal sizing and placement of STATCOM, TCSC and UPFC using a novel hybrid genetic algorithm-improved particle swarm optimization by Urbanus Mwanzia Ngei, Abraham Mutunga Nyete, Peter Musau Moses, Cyrus Wekesa

“…In this paper, a multi-objective function comprising of minimization of power loss (PL), voltage deviation (VD) and operational cost (OC) was formulated and solved using a novel algorithm. …”
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Modal Shift in Public Transport Under Fiscal-Based Policies Scenarios for Jakarta by Alfa Adib Ash Shiddiqi, Dwita Sutjiningsih, Tri Tjahjono, Linda Darmajanti, Gede B. Suprayoga

“…A stated preference survey was conducted, and a binomial logit model and standard utility function were developed for analysis. Diagrams showing commuters' willingness to shift to public transport were then generated from the analysis. …”
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PATH PLANNING AND OBSTACLE AVOIDANCE METHODS FOR AUTONOMOUS MOBILE ROBOTS by Ihor Berizka

“…The modification of the classical artificial potential field method using the Gaussian function to describe repulsive forces is an example of optimizing the method for systems with constrained resources. …”
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