235 Root cause analysis of barriers and facilitators to accrual to a pragmatic, EHR-embedded clinical trial by Lindsay Lennox, Bethany M Kwan, Adit A Ginde, Thomas W. Flaig, Sarah V Kautz, Matthew Mimnall, Andrew Nicklwsky, Goldie Komaie, Christine Velez, Aaron Babour, Laurie Blmberg-Romero, Cecilia C. Low Wang

“…We summarized data from the EHR by eligibility, provider encounters, and alerts, and generated CONSORT diagrams and tables to trace the enrollment pathway. …”
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Linear Active Disturbance Rejection Control-Based Voltage Controller for Buck and Boost DC/DC Converters in DC Distribution Grids by Asimenia Korompili, Oemer Ekin, Marija Stevic, Veit Hagenmeyer, Antonello Monti

“…In addition, the physical significance of the converter’s states allows the integration of additional control functions, relying on the electrical quantities of the converter, for the enhancement of the performance of the voltage controller. …”
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The sporophytic type of fertility restoration in the A3 CMS-inducing cytoplasm of sorghum and its modification by plant water availability conditions by L. A. Elkonin, V. V. Kozhemyakin, M. I. Tsvetova

“…For the first time, the transgenerational effect of water availability conditions of growing a fertility-restoring line on male fertility of the F2 generation was detected: a pollinator grown in a plot with additional irrigation produced more fertile and less sterile individuals compared to the same pollinator grown under a rainfall shelter (p < 0.01), and the segregation pattern changed from digenic to monogenic, indicating heritable inhibition of the expression of one of the fertility-restoring genes (kind of “grandfather effect”). …”
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Reactive Oxygen Species: A Double-Edged Sword in the Modulation of Cancer Signaling Pathway Dynamics by Manisha Nigam, Bajrang Punia, Deen Bandhu Dimri, Abhay Prakash Mishra, Andrei-Flavius Radu, Gabriela Bungau

“…By systematically integrating data on ROS source-specific functions and redox-sensitive signaling pathways, the complex interplay between ROS concentration, localization, and persistence is elucidated, revealing how these factors dictate the paradoxical support of tumor progression or induction of cancer cell death. …”
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Revisiting Cosa (Ansedonia, Italy): contributions of SAR-X images from the PAZ satellite to non-invasive archaeological prospecting by José Ignacio Fiz Fernández, Pere Manel Martín Serrano, Maria Mercè Grau Salvat, Antoni Cartes Reverté

“…As an addition, the Digital Terrain Model (DTM) Light Detection And Ranging (LiDAR) of the Region of Tuscany was used, on which various functions of the Relief Visualization Tool (RVT) programme have been applied, complementing or contrasting the results. …”
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Mucosal microbiota signatures reveal diagnostic insights in chronic liver disease by Sadık Dinçer, Yakup Ülger, Anıl Delik

“…The intestinal microbiota acts as a bioreactor for autonomous metabolic and immunological functions in regulating the host’s response to external stimuli in the intestinal microbiota. …”
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ENERGY EFFICIENCY OF DIFFERENT WAYS OF CENTRAL HEATING by A. E. Piir, V. B. Kuntysh, A. Yu. Vereshchagin

“…Universal electric power plant is comparable in effi- ciency with heat pump system, but outperforms it due to its multi-functionality.…”
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Selisistat, a SIRT1 inhibitor, enhances paclitaxel activity in luminal and triple-negative breast cancer: in silico, in vitro, and in vivo studies by Anna Wawruszak, Jarogniew Luszczki, Damian Bartuzi, Joanna Kalafut, Estera Okon, Arkadiusz Czerwonka, Andrzej Stepulak

“…Accumulative evidence suggests that each sirtuin possesses individual character, implicating its role in the regulation of multifaceted biological functions leading to BC initiation, progression and metastasis. …”
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Cation-induced topical disordered niobium nickel oxide for robust hydrogen storage in magnesium hydride by Shuai Li, Liuting Zhang, Fuying Wu, Qian Li

“…Herein, efficient regulation of electronic and structural rearrangements in niobium-rich nickel oxides was achieved through precise compositional design and niobium cation functionalized doping, thereby greatly enhancing its intrinsic catalytic activity in hydrogen storage systems. …”
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Vitamin C, Sugar Content, Color Intensity and Some Physicochemical Properties of Watermelon and Orange Peels by Selvican Gökçe, İsa Arslan Karakütük, Memnune Şengül

“…Objective: Peels generated as waste during the consumption and processing of fruits and vegetables contribute to both nutritional losses and environmental pollution. …”
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SOCIAL COMPETENCE FORMATION AMONG TEENAGERS FROM HUMANIST TREND MULTIPLE-AGED GROUPS by Larisa A. Krapivina

“…Based on the Children and Youth Public Centre «Carabela» that has been working in Yekaterinburg for more than fifty years, the author discloses how to use the technology of inter-age communication and interaction to provide the continuity of traditions, to preserve historical memory, to transfer humanistic ideas in the chain of generations, and to create personality with sound emotional and moral compass. …”
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Structural barriers and facilitators to accessing postsurgical rehabilitation in adults who were treated with surgery for low back pain: protocol for a scoping review by Jessica J. Wong, Jen Rinaldi, Paulo Pereira, Silvano Mior, Lauren Ead, Alanna Veitch, Kent Murnaghan, Pierre Côté

“…A proportion of patients with LBP undergo surgery and require postsurgical rehabilitation to optimize functioning. However, many encounter barriers to accessing rehabilitation due to structurally generated inequities linked to socioeconomic position. …”
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JAUNOSIOS KARTOS KATALIKŲ INTELEKTUALŲ POŽIŪRIS Į FAŠIZMĄ IR NACIONALSOCIALIZMĄ TARPUKARIO LIETUVOJE by Valdas Pruskus

“…Exactly here the new standpoint on democracy, a state and its functioning was being formed. Trying to understand more deeply the origin and character of this phenomenon, the intellectual Catholic youth singled out two expressions of it - fascism and national-socialism. …”
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JAUNOSIOS KARTOS KATALIKŲ INTELEKTUALŲ POŽIŪRIS Į FAŠIZMĄ IR NACIONALSOCIALIZMĄ TARPUKARIO LIETUVOJE by Valdas Pruskus

“…Exactly here the new standpoint on democracy, a state and its functioning was being formed. Trying to understand more deeply the origin and character of this phenomenon, the intellectual Catholic youth singled out two expressions of it - fascism and national-socialism. …”
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JAUNOSIOS KARTOS KATALIKŲ INTELEKTUALŲ POŽIŪRIS Į FAŠIZMĄ IR NACIONALSOCIALIZMĄ TARPUKARIO LIETUVOJE by Valdas Pruskus

“…Exactly here the new standpoint on democracy, a state and its functioning was being formed. Trying to understand more deeply the origin and character of this phenomenon, the intellectual Catholic youth singled out two expressions of it - fascism and national-socialism. …”
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Targeting key angiogenic pathways with a bispecific CrossMAb optimized for neovascular eye diseases by Jörg T Regula, Peter Lundh von Leithner, Richard Foxton, Veluchamy A Barathi, Chui Ming Gemmy Cheung, Sai Bo Bo Tun, Yeo Sia Wey, Daiju Iwata, Miroslav Dostalek, Jörg Moelleken, Kay G Stubenrauch, Everson Nogoceke, Gabriella Widmer, Pamela Strassburger, Michael J Koss, Christian Klein, David T Shima, Guido Hartmann

“…Modification of RG7716's FcRn and FcγR binding sites disabled the antibodies' Fc‐mediated effector functions. This resulted in increased systemic, but not ocular, clearance. …”
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Interventions to improve mental health and well-being in care-experienced children and young people aged less than 25: the CHIMES systematic review by Rhiannon Evans, Sarah MacDonald, Robert Trubey, Jane Noyes, Michael Robling, Simone Willis, Soo Vinnicombe, Maria Boffey, Charlotte Wooders, Asmaa El-Banna, GJ Melendez-Torres

“…This is in contrast to a more comprehensive, if equivocal, evidence base internationally, particularly in the USA. …”
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A glyco-engineering approach for site-specific conjugation to Fab glycans by Maria L. Jaramillo, Traian Sulea, Yves Durocher, Mauro Acchione, Melissa J. Schur, Anna Robotham, John F. Kelly, Marie-France Goneau, Alma Robert, Yuneivy Cepero-Donates, Michel Gilbert

“…In conventional ADCs, the drug molecules are chemically attached randomly to antibody surface residues (typically Lys or Cys), which can interfere with epitope binding and targeting, and lead to overall product heterogeneity, long-term colloidal instability and unfavorable pharmacokinetics. Here, we present a more controlled process for generating ADCs where drug is specifically conjugated to only Fab N-linked glycans in a narrow ratio range through functionalized sialic acids. …”
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The role of epigenetics in male and female infertility by D. A. Egorova, V. V. Derezina, M. V. Chebanyan, M. B. Sultonova, T. V. Ishmuratov, M. M. Gasanov, A. Z. Chipchikova, S. A. Paksileva, S. S. Mitkina, R. R. Khamidullina, A. Sh. Kutueva, A. A. Anikeeva

“…Despite that epigenetic mechanisms, genes, nutrition and dietary supplements discussed here affect infertility, while a relevant recommended dose has not yet been determined, it was noted that such parameters may positively influence fertility. However, more comprehensive and longitudinal human studies are required to examine their relationship to male and female reproductive functions.…”
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Optimized Nitrogen Foam Flooding System for Enhanced Oil Recovery: Development and Field Test in Mu146 Block Medium-High Permeability Reservoir, China by Jia-Yang Luo, Zhen-Jun Wang, Xin-Yuan Zou, Quan Xu, Bo Dong, Song-Kai Li, Zhu-Feng Wang, Jie-Rui Liu, Xian-Feng Wang, Xiao-Hu Xue

“…The validity period of the NSSNFHF field test is more than 12 months. The technology demonstrates dual functionality in conformance control and enhanced recovery, effectively improving both oil productivity and ultimate recovery factors.…”
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