The Effect of Hydrogen Peroxide on Biogas and Methane Produced from Batch Mesophilic Anaerobic Digestion of Spent Coffee Grounds by Siham Sayoud, Kerroum Derbal, Antonio Panico, Ludovico Pontoni, Massimiliano Fabbricino, Francesco Pirozzi, Abderrezzaq Benalia

“…Further, while previous research has established oxidative pretreatment efficacy, this study uniquely combines the empirical analysis of H₂O₂ pretreatment with a detailed kinetic modeling approach using the modified Gompertz (MG) and logistic function (LF) models to estimate kinetic parameters and determine the accuracy of fit. …”
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Sepsis beyond bundles: contextualising paediatric care in resource-limited settings through situational analysis by John Adabie Appiah, Leah Ratner, Sheila Agyeiwaa Owusu, Ahmet Uluer, Gustav Nettey, Allysa Warling, Charles Martyn-Dickens, Emma Otchere, R. Elaine Cagnina, Maame Fremah Kotoh- Mortty, Eugene Martey

“…Paediatric sepsis bundles, which include prompt administration of antibiotics, fluid resuscitation and continuous organ function monitoring, are crucial for improving outcomes, especially when initiated within the first ‘golden hour’ of sepsis recognition. …”
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Biomarkers for neurodegenerative diseases in regulatory decision‐making by the European Medicines Agency by Audrey M. M. Hermans, Elisabeth Bakker, Viktoriia Starokozhko, Loes den Otter, André J. A. Elferink, Angela Bradshaw, Lorenzo Guizzaro, Peter G. M. Mol, Anna M. G. Pasmooij

“…BMs were categorized based on both nature and function. RESULTS In total, 105 procedures that discussed BMs were analyzed, 57 SAs (January 2020 to December 2022), 19 QAs/QOs (January 2008 to December 2023), and 29 MAAs (January 1995 to December 2023). …”
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Prediction of dam deformation using adaptive noise CEEMDAN and BiGRU time series modeling by WANG Zixuan, OU Bin, CHEN Dehui, YANG Shiyong, ZHAO Dingzhu, FU Shuyan

“…【Method】The model uses sample entropy reconstruction and the K-means clustering algorithm to optimize the adaptive noise complete ensemble empirical mode decomposition with adaptive noise (CEEMDAN) process, generating multiple intrinsic mode functions (IMF). …”
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Mental Health in the Age of Hyperconnectivity: A Crisis Hidden in Plain Sight by Sitara Ejaz, Hafiz Muhammad Haseeb Khaliq

“…Data indicates that individuals who spend more than three hours daily on social media face a 60% higher likelihood of developing anxiety or depressive symptoms 5. …”
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TODAY'S CONSUMERS ON THE MARKET IN CSÍKSZEREDA (MIERCUREA CIUC) by Emőke Katalin Péter, László Illyés

“… Due to the geographical situation of Harghita County, farming mostly in small agricultural areas encourages farmers to engage in more integrated agricultural activities. As a result, more and more farmers who are open to development are starting to appear on local markets with processed products. …”
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Epidemiology and hospitalization costs of chronic kidney disease in Romania by Ildiko Aliz Bradacs, László-István Bába, László Lorenzovici, Andreea Mihaela Precup, Szabolcs Farkas- Ráduly, Gyongyi Tar, Vasile Nastase, Lucia Georgeta Daina, Raul Bozu, Gyula Jozsef Nagy, Dimitrie Cristian Siriopol, Dorel Sandesc, Ovidiu Horea Bedreag, Florin Buicu, Gabriel Mircescu, Gener Ismail

“…Abstract Background Chronic kidney disease or chronic renal failure is a progressive condition defined as abnormalities of kidney structure or function, present for longer than 3 months. It is estimated to affect more than 10% of the general population worldwide. …”
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RNA interference of Aspergillus flavus in response to Aspergillus flavus partitivirus 1 infection by Yinhui Jiang, Yinhui Jiang, Xiang Liu, Xiang Liu, Xun Tian, Xun Tian, Jianhong Zhou, Jianhong Zhou, Qinrong Wang, Qinrong Wang, Bi Wang, Bi Wang, Wenfeng Yu, Wenfeng Yu, Yanping Jiang, Tom Hsiang, Xiaolan Qi, Xiaolan Qi

“…These results provide a better understanding of the functional role of RNAi in the impact of AfPV1 on the hypovirulence of A. flavus.…”
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LcIMT1, a litchi inositol methyl transferase gene, is responsible for d-bornesitol biosynthesis and confers drought tolerance by Liang-Liang Huang, Xin-Ying Li, Fang-Fang Liu, Xu-Ming Huang, Ren-Fang Zeng, Farhat Abbas, Hui-Cong Wang

“…l-quebrachitol, also known as 2-O-methyl-l-chiro-inositol, is a common form of methylated cyclitol found in Litchi chinensis, accounting for more than half of the soluble sugars. Nonetheless, the biological function of l-quebrachitol is somewhat restricted. …”
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Fusion of RetinaFace and improved FaceNet for individual cow identification in natural scenes by Lingling Yang, Xingshi Xu, Jizheng Zhao, Huaibo Song

“…FaceNet's core feature network was enhanced through MobileNet integration, and the loss function was jointly optimized with Cross Entropy Loss and Triplet Loss to achieve a quicker and more stable convergence curve. …”
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AI in Home Care—Evaluation of Large Language Models for Future Training of Informal Caregivers: Observational Comparative Case Study by Clara Pérez-Esteve, Mercedes Guilabert, Valerie Matarredona, Einav Srulovici, Susanna Tella, Reinhard Strametz, José Joaquín Mira

“… BackgroundThe aging population presents an accomplishment for society but also poses significant challenges for governments, health care systems, and caregivers. Elevated rates of functional limitations among older adults, primarily caused by chronic conditions, necessitate adequate and safe care, including in-home settings. …”
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Unique target binding by the C-terminal region of FHR1 provides a new perception of aHUS pathology by Luce Perie, Selina Stippa, Christoph Saffer, Christoph Saffer, Andrea Hartmann, Mathias Mörgelin, Svante L. H. Zipfel, Marc Thilo Figge, Marc Thilo Figge, Thorsten Wiech, Christine Skerka, Peter F. Zipfel, Peter F. Zipfel

“…The action profiles of FHR1 and Factor H were calculated and compared.ResultsFunctional data revealed that residues YVQ vs HLE in SCR3 and LA vs SV in SCR5 altered ligand binding and surface interaction, influenced target recognition and complement control. …”
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Smartphone-based Monitoring and cognition Modification Against Recurrence of Depression (SMARD): An RCT of Memory Bias Modification Training vs. Cognitive Control Training vs. Atte... by N. Ikani, A. Tyborowska, N. Kohn, N. Günther, G J. Siegle, A. H. Schene, J. A. S. Vorstman, C. J. Harmer, M. J. Kas, J. N. Vrijsen, H. G. Ruhé

“…Abstract Background Major Depressive Disorder (MDD) has a 50–80% recurrence rate highlighting the urgent need for more efficient recurrence prevention programs. Currently, recurrences are often identified too late, while existing preventive strategies may not sufficiently address ethio-patho-physiological mechanisms for recurrence. …”
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In Silico and In Vitro Studies of the Approved Antibiotic Ceftaroline Fosamil and Its Metabolites as Inhibitors of SARS-CoV-2 Replication by Cássia Delgado, Pablo Andrei Nogara, Milene Dias Miranda, Alice Santos Rosa, Vivian Neuza Santos Ferreira, Luisa Tozatto Batista, Thamara Kelcya Fonseca Oliveira, Folorunsho Bright Omage, Flávia Motta, Izabela Marques Bastos, Laura Orian, João Batista Teixeira Rocha

“…The 1,2,4-thiadiazole functional group is an inhibitor of cysteine proteases, such as papain and cathepsins. …”
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Caged-hypocrellin mediated photodynamic therapy induces chromatin remodeling and disrupts mitochondrial energy metabolism in multidrug-resistant Candida auris by Xinyao Liu, Yiran Tao, Linwan Zhang, Yuzhou Liu, Dongmei Shi, Jiao Wang, Peng Xue, Bin Xu, Wenjie Fang, Yuping Ran

“…Confocal imaging confirmed that high-dose COP1T-HA-mediated PDT induces localized ROS accumulation near the nucleus and a temporally ordered cellular stress response. Furthermore, functional validation through QCR10, NDUFA5, and MP knockouts confirmed the essential roles of these genes in mitochondrial integrity, ATP synthesis, ROS homeostasis, and biofilm formation. …”
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Sensing of Liver‐Derived Nicotinamide by Intestinal Group 2 Innate Lymphoid Cells Links Liver Cirrhosis and Ulcerative Colitis Susceptibility by Jing Shen, Zhen Li, Xiaoyu Liu, Mengqi Zheng, Peng Zhang, Yatai Chen, Qiuheng Tian, Wenyu Tian, Guanjun Kou, Yanyan Cui, Bowen Xu, Yunjiao Zhai, Weijia Li, Xiaohuan Guo, Ju Qiu, Chunyang Li, Ran He, Lixiang Li, Chunhong Ma, Yanqing Li, Xiuli Zuo, Detian Yuan, Shiyang Li

“…Mechanistically, the NAD+ salvage pathway regulates gut ILC2s in a cell‐intrinsic manner by supporting the generation of succinate, which fuels the electron transport chain to sustaining ILC2s function. …”
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The Ethical Significance of Brain-Computer Interfaces as Enablers of Communication by Toma Gruica

“…Much of the public discourse surrounding BCIs has centered on high-profile commercial ventures—such as Elon Musk’s Neuralink—and the controversies these projects generate. These controversies include the ethics of animal testing protocols, speculative claims regarding human enhancement and human-AI symbiosis, and the broader societal implications of merging minds with machines.[1] While these debates are significant, there is a more fundamental ethical dimension inherent to BCIs. …”
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Experimental Study on Hydraulic Characteristics of Fish-friendly Culverts with Baffles by MAO Jing-qiao, LU Peng, GONG Yi-qing, GAO Huan, DAI Jie

“…The transient vortices formed had planes parallel to the fish’s spine and body axis, reducing energy loss during upstream movement and improving swimming efficiency through vortex energy transfer. This provided a more favorable flow environment for weak-swimming fish species. …”
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Proses Kreatif Komposisi Karawitan “Gesang” Sebagai Wujud Representasi Sosial by Vivi Euis Susanti, Tri Suhatmini

“…The findings indicate that Gesang achieves an aesthetically rich musical form and exemplifies how karawitan can function as an expressive medium responsive to contemporary cultural developments. …”
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HEMOPHILIA: ADVANCES IN TREATMENTS by Nurgül Karakaya

“…Another method is PEGylation, where one or more PEG chains are covalently linked to rFVIII or rFIX. …”
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