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2221
Prediction method of TBM excavation axis deviation for small turning tunnels based on LSTM neural network
Published 2024-12-01“…Firstly, the data is preprocessed, including binary discriminant function and other methods, and the 24 dimensional tunneling parameters are selected by Pearson analysis method as the input of prediction model. …”
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2222
PBMC-Humanized Mouse Model for Multiple Sclerosis: Studying Immune Changes and CNS Involvement
Published 2025-05-01“…Humanized immune system (HIS) mice are powerful tools for studying human immune system function and dysfunction and developing human-specific immunotherapeutics. …”
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2223
A Novel Multi-Image Encryption Scheme Using Generalized Rectangular Transform and Advanced 5-D Hyperchaotic Map
Published 2025-01-01“…In the pixel diffusion phase, a bit-level random permutation (BLRP) technique is employed alongside a Penta-Hyperchaotic Map (PHM), an advanced 5-D discrete memristor and meminductor-based hyperchaotic map, integrated with the SHA-512 hashing function. Unlike traditional pixel-based diffusion methods, BLRP shuffles bits, achieving finer confusion and making structural inference significantly more difficult for attackers. …”
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2224
Prevalence of daily family meals among children and adolescents from 43 countries
Published 2025-01-01“…The meta package was utilized for conducting a meta‐analysis of single proportions, specifically applying the metaprop function. The analysis involved pooling the data using a random‐effects model and presenting the outcomes through a forest plot generated using the inverse variance method. …”
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2225
Muscarinic acetylcholine receptor activated effectors in principal neurons of the rat basolateral amygdala
Published 2025-07-01“…Improved understanding of these effectors will provide potentially valuable new insights on the wide range of mechanisms through which cholinergic system dysfunction can lead to impaired executive function.…”
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2226
A quasi affine transformation evolution algorithm with evolution matrix selection operation for parameter estimation of proton exchange membrane fuel cells
Published 2025-01-01“…It was also computationally more efficient, cutting runtime in half compared to other methods. …”
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2227
A reappraisal of cell cycle phase enrichment in synchronized estrogen receptor-positive cell models derived from breast adenocarcinomas
Published 2025-02-01“…Abstract 17β-estradiol (E2), the main circulating estrogen hormone, is a critical signaling factor for the growth, differentiation, and function of breast epithelial cells. The effects of E2 on the breast tissue are primarily mediated by the estrogen receptor α (ERα). …”
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2228
Application of the U-Net Deep Learning Model for Segmenting Single-Photon Emission Computed Tomography Myocardial Perfusion Images
Published 2024-12-01“…The best results were achieved with the holdout split and cross-entropy loss function, yielding a test accuracy of 98.9%, a test IOU of 89.6%, and a test Dice coefficient of 94%. …”
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2229
Improved Artificial Bee Colony Optimization Underwater Localization Algorithm by Logistic Chaos Mapping and Differential Evolution
Published 2025-01-01“…The chaotic sequence generated by the mapping function was employed as a replacement for the random number generator, with the objective of achieving a more uniform distribution of the population during the initial distribution phase. …”
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2230
Exploring district implementation of national guidelines and maintenance of essential health services during the COVID-19 pandemic in Uganda
Published 2025-05-01“…Future emergency responses should consider how to balance local adaptations with central support by identifying which health system functions districts can more easily manage and adjust independently.…”
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2231
Heavy Metal Immobilization by Phosphate-Solubilizing Fungus and Phosphogypsum Under the Co-Existence of Pb(II) and Cd(II)
Published 2025-07-01“…The functional group analysis of ATR-IR also confirmed the phenomenon. …”
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2232
Novelle approach to simulating spinal cord stimulation during tSCS using CT images and FEM
Published 2024-12-01“…Later versions of FEM models incorporated more organs and had improved on previous mesh generation flaws, but encountered new mesh generation errors which could not be rectified before the conclusion of the master’s project. …”
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2233
HyQ2: A Hybrid Quantum Neural Network for NextG Vulnerability Detection
Published 2024-01-01“…As fifth-generation (5G) and next-generation communication systems advance and find widespread application in critical infrastructures, the importance of vulnerability detection becomes increasingly critical. …”
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2234
Characteristic analysis of N 6-methyladenine in different parts of yak epididymis
Published 2025-05-01“…Conclusions In summary, we generated the m6A profile of the yak epididymis, which will aid in further elucidating the maturation process of sperm and reveal more information related to male infertility.…”
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2235
Preclinical platform for long-term evaluation of immuno-oncology drugs using hCD34+ humanized mouse model
Published 2020-10-01“…We proved the development of functional T cells by demonstrating the anticancer effect of the programmed cell death-1 (PD-1) inhibitor in our humanized mice but not in non-humanized NSG mice. …”
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2236
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2237
Type 1 diabetes prevention clinical trial simulator: Case reports of model‐informed drug development tool
Published 2024-08-01“…We then applied trial‐specific inclusion/exclusion criteria, sample sizes in treatment and placebo arms, trial duration, assessment interval, and dropout rate. We implemented a function for presumed drug effects. To increase the size of the population pool, we generated virtual populations using multivariate normal distribution and ctree machine learning algorithms. …”
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2238
Subcooled flow boiling in diamond/Cu microchannel heat sinks for near-junction chip cooling
Published 2025-05-01“…In this study, three structurally functional integrated open microchannel heat sinks (DC60, DC75, and MoCu50) were innovatively created using low-linear-expansion materials such as DC and molybdenum-copper as the substrates. …”
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2239
Treatment of bacterial biothreat agents with a novel purified bioactive lactoferrin affects both growth and biofilm formation
Published 2025-06-01“…Lactoferrin is known to exhibit broad spectrum activity against a multitude of bacteria, fungi, and viruses due to its multi-functional mode of action. Recently, Lactea Therapeutics and its affiliates have developed a novel, patent-pending technology to purify naturally derived bovine lactoferrin (Lactea Lf) for use as a medical countermeasure that was not previously available. …”
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2240
Differences in neuronal ciliation rate and ciliary content revealed by systematic imaging-based analysis of hiPSC-derived models across protocols
Published 2025-04-01“…Interestingly, we found that while GPR161 signal almost completely disappeared from cilia upon Sonic hedgehog (SHH) stimulation in NSCs and immature neurons, this was not the case in more mature neurons, suggesting a possible developmental time window for cilia-dependent SHH signaling.ConclusionTaken together, our results provide a systematic description of cilia in hiPSC-derived neuronal cells generated with different protocols, underscoring the importance of selecting the optimal model system and controls for investigating primary cilia in hiPSC-derived neuronal cells.…”
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