The Design of a Randomized Controlled Active Comparator Strategy Trial for Gout: Treat to Target Serum Urate Versus Treat to Avoid Symptoms by Daniel H. Solomon, Misti Paudel, Shravani Chitineni, Ana Fernandes, Tammy Pham, Shreya Billa, Chio Yokose, Kiara Tan, Julien J. Dedier, Maureen D. Dubreuil, John D. Fitzgerald, Sally L. Hodder, Tuhina Neogi, Michael H. Pillinger, Kevin R. Riggs, Kenneth G. Saag, Paul G. Shekelle, Zoe Tseng, Michael Toprover, David S. Wei, Michael J. Barry, Hyon K. Choi

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Healthcare needs, care use and health status outcomes in adults with Bardet-Biedl syndrome: a cross-sectional study in Norway by Cecilie Fremstad Rustad, Ragnheidur Bragadottir, Hilde Nordgarden, Jeanette Ullmann Ullmann Miller, Mina Susanne Weedon-Fekjær, Shahrzad Arfa, Pamela Marika Åsten, Kristian Tveten, Charlotte von der Lippe, Solrun Sigurdardottir

“…Compared with those in the general population, adults with BBS reported significantly more problems (EQ-5D-5L) with mobility, self-care, and usual activities (all p<0.001).Conclusions Most adults with BBS have unmet physical, social and medical needs, with the majority having unmet rehabilitation needs that require special attention. …”
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Longitudinal Observational Study on Quality of Life in Patients with Chronic Wounds Using DLQI and EQ-5D by David Palomar-Albert, Jorge Zamora-Ortiz, Federico Palomar-Llatas, Marta Escudero-Martínez, Alba Naranjo-Cuellar, Maria Isabel Pastor-Orduña

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Temperature compensated crystal oscillator design in Keysight ADS by A. N. Lyashuk, A. V. Kosykh

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Brainwave Activity Localization, Mood Symptoms, and Balance Impairment in a Male South African Rugby Player With Persisting Symptoms After Concussion: A Case Report by M. J. Lumb, N. Snegireva, A. M. Coetzee, K. E. Welman

“…The protocol provides a framework for clinicians to monitor a patient's recovery progress in terms of brainwave activity, general cognition, moods, and motor control. Objective data obtained through the protocol may assist in developing personalized treatment plans, improving follow‐up care, and identifying residual brain function deficits that may be missed in standardized clinical exams. …”
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Global thrombosis test for assessing thrombotic status and efficacy of antithrombotic diet and other conditions by Masahiro Murakami, Kazunori Otsui, Yoshinobu Ijiri, Muneshige Shimizu, Hideo Ikarugi, Wataru Shioyama, Junichiro Yamamoto, Kjell S Sakariassen

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The main trends of dynamics of incomes of Russians in times of economic crisis by O. L. Petryakova

“…The majority of families in Russia, according to sociological researches, don’t hope for bystry improvement of an economic situation (both own, and the countries in general), are afraid of further deterioration in a situation that, in turn, breaks psychological climate in a family, affecting performance of the functions by her. …”
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Preserved Ratio Impaired Spirometry in US Primary Care Patients Diagnosed with Chronic Obstructive Pulmonary Disease by Evans A, Tarabichi Y, Pace WD, Make B, Bushell N, Carter V, Chang KL, Fox C, Han MK, Kaplan A, Kocks JWH, Le Lievre C, Roussos A, Skolnik N, Soriano JB, Yawn BP, Price D

“…Multivariable logistic regression was performed to assess whether PRISm predicts lung function decline.Results: Prevalence of PRISm within a primary care population clinically diagnosed with COPD was 23.6% (678/2866, 95% CI 22.0– 25.1). …”
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Integrative spatial and single-cell transcriptomics elucidate programmed cell death-driven tumor microenvironment dynamics in hepatocellular carcinoma by Kai Lei, Kai Lei, Yutong Zhao, Shumin Li, Jiawei Liu, Wenhao Chen, Caihong Zhou, Yi Zhang, Jinmei Tan, Jian Wu, Qi Zhou, Qi Zhou, Jiehui Tan

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Comprehensive analysis through multi-omics integration to compare and elucidate the specific substances in milk of donkey、horse、camel、human and pig by Qiu Zhang, Qian Li, Xiaowei Wang, Yanzhi Wu, Rui Chen, Yinggang Sun, Yuan Pan, Siyi Li, Zeying Wang

“…Featured milk generally refers to less common dairy products with unique sources or specific nutritional components and functional characteristics. …”
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Vision-related Quality of Life (VRQOL) and its determinants among the Elderly in rural blocks of Haryana, India by Mona Duggal, Ankita Kankaria, Latika Rohilla, Harashish Jindal, Limalemla Jamir, Parul Chawla Gupta, Debarati Sarkar, Vaibhav Miglani, Akash Kumar, Drishti Sharma, Neha Dahiya, Siddhartha Sharma, Sandeep Grover

“…The study found higher VR-QOL scores in General Health, Distance activities, and Near activities, while lower scores were observed in Mental health, Dependency, Social functioning, Ocular pain, General vision, and Role difficulties. …”
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Reshaping the experience of topical skincare products: A multisensory approach for promoting loyalty and adherence by Brayan Rodríguez, Ana Arboleda, Felipe Reinoso-Carvalho

“…The increasingly competitive skincare market demands more engaging consumer experiences to foster loyalty and adherence. …”
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Role of Iron in Children With Immunoglobulin A Nephropathy and Macrohematuria-Induced Acute Kidney Injury by Shingo Ishimori, Tomoko Horinouchi, Tomohiko Yamamura, Junya Fujimura, Naohiro Kamiyoshi, Hiroshi Kaito, Yuriko Tanaka, Hiroyoshi Matsukura, Wataru Shimabukuro, Yuko Shima, Azusa Kawaguchi, Yoshinori Araki, Koichi Nakanishi, Shigeo Hara, Kandai Nozu

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Exosomes as Emerging Regulators of Immune Responses in Type 2 Diabetes Mellitus by Wei Zheng, Xin Ji, Qiao qiao Yin, Chensi Wu, Chengan Xu, Hongying Pan, Chun Wu

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Epidemiologic threats and outcome of evolving COVID-19-associated mucormycosis from a referral hospital in Egypt by Safaa Elserougy, Muhammad Abdel-Ghaffar, Eman Medhat, Ahmed Heiba, Weam Shaheen, Elham Mostafa, Hala Mahfouz, Samah Abdel-Hafez, Mohammad S Mahfouz, Shimaa Afify, Omnia Ali, Enass El-Sayed, Ahmed M Mostafa, Ahmed M Salah, Anwar Elbatawy, Hanan M Elghoneimy, Amr A Elshafey, Ahmed Abou-ElFotouh, Tareq Abdul-Ghani, Fatma I Ibrahim, Sarah M Samy, Manal S Elhussini

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A specific microbial consortium enhances Th1 immunity, improves LCMV viral clearance but aggravates LCMV disease pathology in mice by Daphne Kolland, Miriam Kuhlmann, Gustavo P. de Almeida, Amelie Köhler, Anela Arifovic, Alexandra von Strempel, Mohsen Pourjam, Silvia Bolsega, Christine Wurmser, Katja Steiger, Marijana Basic, Klaus Neuhaus, Carsten B. Schmidt-Weber, Bärbel Stecher, Dietmar Zehn, Caspar Ohnmacht

“…Here, we show that a defined, low complex bacterial community (OMM12) but not the general absence of microbes in germ-free mice leads to a more potent immune response compared to the microbiome of specific-pathogen-free (SPF) mice after a systemic viral infection with LCMV Clone-13. …”
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OPTIMIZATION OF IMID-BASED THERAPIES by Murat Çınarsoy

“…Although there are classical findings such as anemia, bone disease, loss of renal function, hypercalcemia, a significant proportion of patients suffer from sleep disorders, anxiety and depression, pain, malnutrition, which are not less common than classical signs and symptoms and lead to serious deterioration in the patient's quality of life.Due to the advanced age of most patients, polypharmacy, defined as the use of 4 or more drugs, can reach 80% in multiple myeloma patients, while inappropriate drug complications can reach 50%.Treatment compliance was 68% and treatment discontinuation rate was 36%. …”
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Characterization of Field of View in Visible Light Communication Systems for Intelligent Transportation Systems by Marco Seminara, Tassadaq Nawaz, Stefano Caputo, Lorenzo Mucchi, Jacopo Catani

“…Our results could be very relevant in the near future to assess a most suited solution in terms of acceptance angle when designing a VLC system for real applications, where angle-dependent misalignment effects play a non-negligible role, and we argue that they could have more general implications with respect to the pristine I2V case mentioned here.…”
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Exploring Motor–Cognitive Interference Effects and the Influence of Self-Reported Physical Activity on Dual-Task Walking in Parkinson’s Disease and Healthy Older Adults by Thomas Jürgen Klotzbier, Nadja Schott, Soo-Yong Park, Quincy J. Almeida

“…More intensive or DT-specific exercise may be required to reduce interference effects. …”
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E3 ubiquitin ligase FBXW11-mediated downregulation of S100A11 promotes sensitivity to PARP inhibitor in ovarian cancer by Ligang Chen, Mingyi Wang, Yunge Gao, Yanhong Lv, Lianghao Zhai, Jian Dong, Yan Chen, Xia Li, Xin Guo, Biliang Chen, Yi Ru, Xiaohui Lv

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