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1721
Model of the DGEBA-EDA Epoxy Polymer: Experiments and Simulation Using Classical Molecular Dynamics
Published 2019-01-01“…Polyepoxy samples are synthesized from diglycidylether of bisphenol A (DGEBA) and ethylene diamine (EDA) monomers at a stoichiometric ratio of 2 DGEBA : 1 EDA in model conditions in order to promote a high degree of polymerization and a low density of defects and to try to approach the ideal models obtained by simulation. …”
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1722
The mitochondrial genome of <i>Dendrobaena tellermanica</i> Perel, 1966 (Annelida: Lumbricidae) and its phylogenetic position
Published 2023-04-01“…The control region contained multiple hairpins, as well as tandem repeats of the AACGCTT monomer. Phylogenetic analysis based on the complete mitochondrial genomes indicated that the genus Dendrobaena occupied the basal position within Lumbricidae. …”
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1723
Screening potential antileukemia ingredients from sweet potato: integration of metabolomics analysis, network pharmacology, and experimental validation
Published 2025-01-01“…Subsequently, based on the results of metabolomics analysis and network pharmacology, cynaroside, nepitrin, and yuanhuanin were identified as potential antileukemia agents present in sweet potato for the first time; while CASP3, KDR, EGFR, and SRC were recognized as pivotal targets of these three monomers against AML. Finally, the antileukemia effects of cynaroside, nepitrin, and yuanhuanin were confirmed through in vitro and in vivo experimental validation.ConclusionIn summary, sweet potato leaves extract possesses an antileukemic effect while cynaroside, nepitrin, and yuanhuanin demonstrate potential as treatments for AML.…”
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1724
Concentrations of Blood Serum and Urinal Ellagitannin Metabolites Depend Largely on the Post-Intake Time and Duration of Strawberry Phenolics Ingestion in Rats
Published 2019-11-01“…The fraction contained monomers and dimers of ellagitannins as well as proanthocyanidins. …”
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1725
Excessive copper induces lignin biosynthesis in the leaves and roots of two citrus species: Physiological, metabolomic and anatomical aspects
Published 2025-01-01“…Besides, 300 µM Cu stress increased the accumulation of three lignin monomers of citrus species. The metabolomic profile indicated that Cu toxicity altered the lignin components of citrus species. …”
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1726
Study of the Interplay Among Melt Morphology, Rheology and 3D Printability of Poly(Lactic Acid)/Poly(3-Hydroxybutyrate-Co-3-Hydroxyvalerate) Blends
Published 2025-01-01“…As a result, its application in FDM has not yet attained mainstream adoption. Introducing a monomer with higher excluded volume, such as hydroxyvalerate, in the PHB primary structure, as in poly(hydroxybutyrate-co-valerate) (PHBV) copolymers, reduces the degree of crystallinity and the melting temperature, hence improving the PHA printability. …”
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1727
A new scheme for boosting in situ Fenton-like reaction in plant pathogenic tissues for selective structural degradation of capsid proteins
Published 2025-02-01“…Our research demonstrated that tCuinter-bCDs possessed functional activity to specifically recognize and proximally degrade CP. tCuinter-bCDs form complexes with CP monomers through supramolecular bonds characterized by significant electrostatic components. …”
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1728
MCU complex: Exploring emerging targets and mechanisms of mitochondrial physiology and pathology
Published 2025-02-01“…In addition, we conducted an in-depth analysis of the regulatory effects of agonists, inhibitors, and traditional Chinese medicine (TCM) monomers on the MCU complex and their application prospects in disease treatment. …”
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1729
Rapid and Efficient Purification of Functional Collectin-12 and Its Opsonic Activity against Fungal Pathogens
Published 2019-01-01“…Purified recombinant CL-12 adopted an oligomeric structure with monomers, dimers, and trimers and retained its binding capacity towards the A. fumigatus strain that has been described before. …”
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1730
Large-scale prospective serum metabolomic profiling reveals candidate predictive biomarkers for suspected preeclampsia patients
Published 2025-02-01“…Moreover, a panel of seven predictive biomarkers including 2-methyl-3-hydroxy-5-formylpyridine-4-carboxylate, gamma-glutamyl-leucine, 2-hydroxyvaleric acid, LysoPC(16:1(9Z)/0:0), PC(DiMe(13,5)/MonoMe(13,5)), ADP-D-glycero-beta-D-manno-heptose and phenylalanyl-tryptophan were identified for PE development by performing multiple statistical analysis and LASSO regression analysis. …”
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1731
Contribution of cuproptosis and immune-related genes to idiopathic pulmonary fibrosis disease
Published 2025-02-01“…The expression of the CTSG showed statistically significant differences in monocyte macrophages.ConclusionThe research methodically depicted the intricate interplay among five cuproptosis-related genes, four immune-related hub genes, and IPF, offering new ideas for diagnosing and treating patients with IPF.…”
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1732
Genetic Variation Analysis of Hsp101 Gene in Common Wild Rice and Asian Cultivated Rice Germplasm Resources
Published 2024-11-01“…【Results】A total of 471 genetic mutations were identified in the region of the Hsp101 gene, among which 94 non-synonymous variation sites resulted in amino acid coding changes. …”
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1733
Extracellular HMGB1 blockade inhibits tumor growth through profoundly remodeling immune microenvironment and enhances checkpoint inhibitor-based immunotherapy
Published 2021-03-01“…Indeed, without affecting the global number of (CD45+) immune cells, drastic reductions of monocytic/granulocytic myeloid-derived suppressor cells (MDSC) and regulatory T lymphocytes, a higher M1/M2 ratio of macrophages as well as an increased activation of both DC and pDC were continually observed following HMGB1 inhibition. …”
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1734
Associations between Children’s Exposure to PM2.5 and their Serum Inflammatory Responses in Taiwan
Published 2022-11-01“…Schoolchildren (n = 183) between the ages of 6 and 12 years living in southern Taiwan were recruited to measure their serum inflammation including interferon-γ (IFN-γ), IFN-α2, interleukin 1b (IL-1b), IL-2, IL-6, IL-10, IL-13, IL-17, monocyte chemotactic protein (MCP)-l, and tumor necrosis factor (TNF-α). …”
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1735
Prevalence of insomnia symptoms and the use of benzodiazepines and Z-drugs for their treatment among medical students
Published 2020-12-01“…From December 2019 to April 2020, 321 medical students from Vilnius University (VU) (138 students) and Lithuanian University of Health Sciences (LUHS) (183 students) participated in an anonymous online survey including 28 multiple choice questions. …”
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1736
Are noise and air pollution related to the incidence of dementia? A cohort study in London, England
Published 2018-09-01“…All exposure measures were linked anonymously to clinical data via residential postcode. …”
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1737
Socio-demographic portrait of the applicant and the main motives for choosing the "Therapy and rehabilitation" speciality
Published 2024-10-01“…To achieve this goal, a voluntary anonymous survey of 39 domestic applicants enrolled to complete the bachelor's degree program in speciality 227 "Therapy and rehabilitation" at Dnipro State Medical University was conducted. …”
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1738
Suicidal ideation and suicide attempt among pregnant adolescent girls in Ghana: a cross-sectional study
Published 2025-01-01“…However, there is a growing concern that suicide research has paid little attention to pregnant adolescent girls, particularly in low-income and middle-income countries, including Ghana, where nearly one in seven adolescents experiences (unwanted) pregnancy.Aims To assess the prevalence and correlates of suicidal ideation and suicide attempt and the self-reported reasons for attempted suicide among pregnant adolescent girls in Ghana.Methods We collected cross-sectional data (between August 2022 and December 2023) using structured anonymous questionnaires from a sample of 449 pregnant adolescent girls (aged 14–19 years) drawn from the three geographical zones of Ghana. …”
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1739
„... nenábožnost nynějšího věku ...“ Proměny zbožnosti ve druhé polovině 19. století očima katolických kněží
Published 2011-01-01“…It was very hard for them to keep track of their parishioners who lived in towns, especially in emerging workers’ settlements, where, due to large fluctuation and anonymity of believers, it was not within priests’ powers to have an awareness of all their flock. …”
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1740
Evidence-informed language: interpretation and impact on intentions to treat – results of an online survey of medical students and specialists in German-speaking countries
Published 2025-02-01“…We explored differences between medical specialists and undergraduate medical students.Design Cross-sectional, anonymous online survey. Assessment was based on publicly available proposals for wording to characterise strength of evidence from randomised versus non-randomised trials and of clinical practice recommendations, respectively.Setting The online survey was conducted between September 2021 and March 2022 and promoted by several professional organisations in German-speaking European countries (Germany, Austria and Switzerland).Participants Medical students, trainees and medical specialist (open to all medical specialties).Outcome The survey was composed of two sections: (1) Aim of the first survey section was to assess if the linguistic differentiation between results from randomised versus non-randomised studies is correctly understood as put forward by the proponents. …”
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