-
1581
The sarcoma ring trial: a case-based analysis of inter-center agreement across 21 German-speaking sarcoma centers
Published 2025-01-01“…Methods In this cross-sectional case-based survey study, 5 anonymized patient cases with imaging data of localized STS were presented to MTBs of 21 German-speaking tertiary referral hospitals. …”
Get full text
Article -
1582
Development of quality indicators for hand osteoarthritis care – Results from an European consensus study
Published 2025-03-01“…A European expert panel, comprising researchers, clinicians, and patient research partners, participated in online meetings to discuss adaptation and suggest new QIs based on treatment recommendations for hand OA, and anonymously rated each suggested QI regarding its importance, validity, usefulness, and feasibility. …”
Get full text
Article -
1583
Assessment of patient preferences for assisted reproductive technology in China: a discrete choice experiment
Published 2025-02-01“…Patients were asked to choose between two scenarios that differed in participation in treatment decision-making (TDM), clinical pregnancy rate, live birth rate, risk of maternal and neonatal complications, and out-of-pocket cost.Setting Jiangsu province, China. The anonymous survey was carried out between December 2022 and February 2023.Participants Female patients aged 20–45 years, with low fertility or experience of ART treatment. …”
Get full text
Article -
1584
The Feasibility and Acceptability of an HIV Web- Based Screening Program in Iran
Published 2025-01-01“…This study aimed to evaluate the feasibility and acceptability of a web-based HIV screening program for identifying individuals with high-risk HIV behaviors in Iran.Methods: A cross-sectional study was conducted using an educational website where individuals could anonymously complete a risk assessment questionnaire. …”
Get full text
Article -
1585
The effects of psychosocial and economic factors on the quality of life of patients with end-stage renal disease and their caregivers in Klang Valley, Malaysia: protocol for a mixe...
Published 2022-06-01“…Informed consent of the participants will be obtained beforehand, and no personal identifiers will be obtained from the participants to protect their anonymity. The findings will be published in peer-reviewed scientific journals and presented at national or international conferences with minimal anonymised data.…”
Get full text
Article -
1586
Preferences and access to community-based HIV testing sites among men who have sex with men (MSM) in Côte d’Ivoire
Published 2022-06-01“…MSM who preferred undifferentiated HIV testing sites mentioned the lack of discretion and anonymity of community-based sites and the desire to avoid the gaze of others.Conclusion Community-based HIV testing is well suited for MSM who identify as homosexual and those close to the MSM community, while maintaining undifferentiated HIV testing is essential for others. …”
Get full text
Article -
1587
RNA editing-based biomarker blood test for the diagnosis of bipolar disorder: protocol of the EDIT-B study
Published 2025-02-01“…Any publication will use fully anonymized data. Publications with the final study results will be disseminated in international peer-reviewed journals and presented at international conferences. …”
Get full text
Article -
1588
Perceptions and future perspectives of medical students on the use of artificial intelligence based chatbots: an exploratory analysis
Published 2025-01-01“…The students were invited to complete a specific questionnaire anonymously and voluntarily, which they could respond to using their mobile devices by scanning a QR code projected on the classroom screen, we used Microsoft Forms to perform the survey.ResultsOut of the 61 students enrolled in the subject, 34 (56%) attended the seminar, of whom 29 (85%) completed the questionnaire correctly. …”
Get full text
Article -
1589
Contemporary Management of Patients With Chagas Cardiomyopathy in Bolivia
Published 2025-03-01“…The Qualtrics survey was distributed anonymously. Survey questions were developed by Bolivian and U.S. researchers with extensive Chagas disease experience. …”
Get full text
Article -
1590
Effects of Mating and Social Exposure on Cell Proliferation in the Adult Male Prairie Vole (Microtus ochrogaster)
Published 2020-01-01“…Microtus ochrogaster is a rodent with a monogamous reproductive strategy characterized by strong pair bond formation after 6 h of mating. …”
Get full text
Article -
1591
Genomic characterization of three marine fungi, including Emericellopsis atlantica sp. nov. with signatures of a generalist lifestyle and marine biomass degradation
Published 2021-08-01“…The Pezizellaceae genome and the genome of the monotypic Amylocarpus genus represent the first published genomes of filamentous fungi that are restricted in their occurrence to the marine habitat and form thus a valuable resource for the community that can be used in studying ecological adaptions of fungi using comparative genomics.…”
Get full text
Article -
1592
Transcription factor RUNX1 regulates coagulation factor XIII-A (F13A1): decreased platelet-megakaryocyte F13A1 expression and clot contraction in RUNX1 haplodeficiency
Published 2025-01-01“…FXIII-A is synthesized by hematopoietic cells, megakaryocytes, and monocytes. Objectives: To understand RUNX1 regulation of F13A1 expression in platelets/megakaryocytes and the mechanisms and consequences of decreased F13A1 in RHD. …”
Get full text
Article -
1593
Deep immunophenotyping of circulating immune cells in major depressive disorder patients reveals immune correlates of clinical course and treatment response
Published 2025-02-01“…Multiparametric analysis was performed on the peripheral blood of 60 MDD patients using flow cytometry to identify lymphocytes (naïve/effector, memory, regulatory) and myeloid cells (dendritic cells, monocytes). We studied the associations between immunophenotype and depressive symptoms, social and working functioning, and subjective quality of life during the acute phase and after three months of treatment. …”
Get full text
Article -
1594
Effect of rhGH treatment on lipidome and brown fat activity in prepuberal small for gestational age children: a pilot study
Published 2025-02-01“…Elevated levels of 1a,1b-dihomo-PGJ2 and adrenic acid suggested potential aging markers. rhGH treatment also significantly reduced meteorin-like (METRNL) and monocyte chemoattractant protein-1 (MCP1) serum levels to control levels. rhGH influences the serum lipidome, promoting changes in maturation and metabolism. …”
Get full text
Article -
1595
The Fabrication and Evaluation of a Potential Biomaterial Produced with Stem Cell Sheet Technology for Future Regenerative Medicine
Published 2020-01-01“…Compared with porcine small intestinal submucosa (SIS) in vivo, the homogeneous decellularized ADSC sheets had less monocyte-macrophage infiltrating in vivo implantation. …”
Get full text
Article -
1596
Immune responses in rodent whole eye transplantation: elucidation and preliminary investigations into rejection diagnosis and monitoring
Published 2025-01-01“…These methodologies collectively contribute to the development of non-invasive diagnostic and monitoring strategies for WET.ResultsOur study revealed a rapid and acute immune response following WET, characterized by an early innate immune response dominated by complement involvement, and infiltration of neutrophils and monocytes by post-operative day (POD) 2. This was succeeded by an acute T-cell-mediated immune reaction, predominantly involving T helper 1 (Th1) cells and cytotoxic T lymphocytes (CTLs). …”
Get full text
Article -
1597
The effect of meningococcal vaccines on new generation of systemic inflammatory markers in children
Published 2025-01-01“…Neutrophil, lymphocyte, monocyte, platelet counts, C-reactive protein (CRP), neutrophil-to-lymphocyte ratio (NLR), derived NLR (dNLR), platelet-to-lymphocyte ratio (PLR), systemic inflammation response index (SIR-I), and systemic immune inflammation index (SII) were evaluated. …”
Get full text
Article -
1598
Identification and validation of glycolysis-related diagnostic signatures in diabetic nephropathy: a study based on integrative machine learning and single-cell sequence
Published 2025-01-01“…GScore was significantly associated with neutrophils and non-classical monocytes. Potential agents including esmolol, estradiol, ganciclovir, and felbamate, targeting the 12 diagnostic signatures were identified. …”
Get full text
Article -
1599
Sickle Cell Anemia Patients Display an Intricate Cellular and Serum Biomarker Network Highlighted by TCD4+CD69+ Lymphocytes, IL-17/MIP-1β, IL-12/VEGF, and IL-10/IP-10 Axis
Published 2020-01-01“…High expression of TLR2 in monocytes and VLA-4 in TCD8+ lymphocytes and high levels of MIP-1β and RANTES appear to be relevant in high death risk conditions. …”
Get full text
Article -
1600
Increased pro-SFTPB in HDL promotes the pro-inflammatory transition of HDL and represents a sign of poor prognosis in ARDS patients
Published 2025-01-01“…Furthermore, the in vitro studies confirmed that the pro-SFTPB enriched HDL significantly promoted M1 polarization of monocyte-derived macrophages. Conclusions The increase of HDL-pro-SFTPB promotes HDL pro-inflammatory transition during septic ARDS, leading to exacerbated progression of ARDS through enhancing M1 macrophage polarization. …”
Get full text
Article