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1121
Sirtuin1 Targeting Reverses Innate and Adaptive Immune Tolerance in Septic Mice
Published 2018-01-01“…Pharmacologically inhibiting SIRT1 deacetylase activity in septic mice reverses monocyte immune tolerance, clears infection, rebalances glycolysis and glucose oxidation, resolves organ dysfunction, and prevents most septic deaths. …”
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1122
To describe the subsets of malignant epithelial cells in gastric cancer, their developmental trajectories and drug resistance characteristics
Published 2025-01-01“…This study employed single-cell RNA sequencing, using the 10 × Genomics platform, to analyze 262,532 cells from gastric cancer samples, identifying 32 distinct clusters and 10 major cell types, including immune cells (e.g., T cells, monocytes) and epithelial subpopulations. Among 27 epithelial subgroups, five malignant subpopulations were identified, each defined by unique marker gene expressions and playing diverse roles in tumor progression. …”
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1123
Pretreatment Pan-Immune-Inflammation Value Efficiently Predicts Survival Outcomes in Glioblastoma Multiforme Patients Receiving Radiotherapy and Temozolomide
Published 2022-01-01“…Each eligible patient’s PIV was calculated using the findings of peripheral blood platelet (P), monocyte (M), neutrophil (N), and lymphocyte (L) counts obtained on the first day of therapy: PIV=P×M×N÷L. …”
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1124
Legal regime of business partnership property (considering international experience)
Published 2023-06-01“…In this sense, property is an economic category and synonymous with the economic concept of “ownership”. …”
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1125
Risk Factors Analysis of Cutaneous Adverse Drug Reactions Caused by Targeted Therapy and Immunotherapy Drugs for Oncology and Establishment of a Prediction Model
Published 2025-01-01“…Nine risk factors were eventually identified: age, treatment modality, cancer types, history of allergies, age‐corrected Charlson comorbidity index, percentage of eosinophils, absolute number of monocytes, Eastern Cooperative Oncology Group Performance Status, and C‐reactive protein. …”
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1126
Genetic tracking of Crimean-Congo haemorrhagic orthonairovirus in Hyalomma population infesting cattle in Nigeria.
Published 2025-01-01“…Additionally, compared to CCHFV isolate IbAr10200 (KY484036), sequences from this study exhibited 9-23 nucleotide variable positions with 3-4 non-synonymous amino acid replacements. Phylogenetic analysis revealed clustering of these strains around IbAr10200, suggesting ongoing circulation. …”
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1127
Polymorphism of the cold receptor gene TRPM8 in native populations of Siberia: putative selective role of rs11563208 polymorphism in Northeast Asia
Published 2017-05-01“…One of them characterized by derived allele T at rs11563208 locus is very interesting because it is spread at the frequency of 14 % only in Northeast Asia (in Koryaks and Chukchi). A synonymous substitution at rs11563208 locus may have a functional role because the amino acid residue (isoleucine at position 1016 of TRPM8 protein) corresponding to this locus is located in functionally important TRP-domain and, hence, it can influence thermoreception processes. …”
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1128
Ecolinguistic dynamics of English loanwords in Chinese: a case study on terms for cement
Published 2024-10-01“…Intense competition arises due to multiple synonyms for the same entity, and adaptation challenges occur when the loanwords do not precisely fit the entity. …”
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1129
Design and Optimization of the Circulatory Cell-Driven Drug Delivery Platform
Published 2021-01-01“…This review specifically covers (a) the properties of red blood cells, monocytes, macrophages, neutrophils, natural killer cells, T lymphocytes, and mesenchymal stem cells; (b) the loading strategies to balance cargo amounts and cell function balance; (c) the cascade strategies to improve cell-driven targeting delivery efficiency; and (d) the features and applications of cell membranes, artificial cells, and extracellular vesicles in cancer treatment.…”
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1130
Kolaviron Improved Resistance to Oxidative Stress and Inflammation in the Blood (Erythrocyte, Serum, and Plasma) of Streptozotocin-Induced Diabetic Rats
Published 2014-01-01“…Serum levels of proinflammatory cytokines and growth factor: interleukin- (IL-) 1, monocyte chemotactic protein-1 (MCP-1), and vascular endothelial growth factor (VEGF), respectively, were also analyzed. …”
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1131
Therapeutic anti-inflammatory immune potentials of some seaweeds extracts on chemically induced liver injury in mice
Published 2025-02-01“…Pre-treatment and post-treatment of P. pavonia and J. rubens extracts in CCL4/mice increased WBCs count and lymphocytes relative numbers and reduced the neutrophils and monocytes relative numbers. Pre-treatment and post-treatment of CCL4/mice with P. pavonia and J. rubens extracts significantly reduced the release amounts of pro-inflammatory cytokines TNF-α and IL-6 and significantly inhibited the increased CRP level. …”
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1132
Good practices for dialysis education, treatment, and eHealth: A scoping review.
Published 2021-01-01“…<h4>Methods</h4>Embase, Pubmed, the Cochrane Library, CINAHL databases and Web of Science were searched for relevant articles using all synonyms for the words 'kidney failure', 'dialysis', and 'good practice'. …”
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1133
A systematic in vitro study of the effect of normoglycaemic and hyperglycaemic conditions on the biochemical and cellular interactions of clinically-available wound dressings with...
Published 2025-01-01“…Dressings presenting absorbent layers made of synthetic, non-woven fibres supported the adhesion of monocytes macrophages and stimulate the release of factors known to play a role in the chronic inflammation. …”
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1134
Examining the Effect of Consuming C8 Medium-Chain Triglyceride Oil for 14 Days on Markers of NLRP3 Activation in Healthy Humans
Published 2022-01-01“…However, consumption of C8 MCT oil for 14 days did not impact markers of monocyte NLRP3 inflammasome activation compared to baseline. …”
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1135
The Effect of Chronic Candesartan Therapy on the Metabolic Profile and Renal Tissue Cytokine Levels in the Obese Zucker Rat
Published 2010-01-01“…An ELISA-based cytokine array revealed that candesartan normalized elevated renal interleukin (IL) 1-β and monocyte chemoattractant protein-1 (MCP-1) levels in OZ. …”
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1136
Adipose-Derived Mesenchymal Stem Cells Promote M2 Macrophage Phenotype through Exosomes
Published 2019-01-01“…In this study, adipose-derived MSCs (AdMSCs) and human peripheral blood monocytes (PBMCs) were isolated and cultured to examine the effects of MSC-induced macrophages (iMΦ) on inflammation and immune modulation. …”
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1137
GGT5 Is an Independent Prognostic Biomarker in Stomach Adenocarcinoma
Published 2022-01-01“…The high-expression GGT5 group had higher concentrations of M2 macrophages, T cell regulators, and monocytes, but the contents of plasma cells and M1 macrophages were higher in the low-expression GGT5 group. …”
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1138
Multiple machine learning-based integrations of multi-omics data to identify molecular subtypes and construct a prognostic model for HNSCC
Published 2025-02-01“…The PRG-based signature stratified patients into low- and high-risk groups, with the low-risk group showing prolonged survival, enhanced immune cell infiltration (B cells, T cells, monocytes), and activated immune functions (cytolytic activity, T cell co-stimulation). …”
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1139
Information and knowledge management: dimensions and approaches
Published 2005-01-01“…The reading of the literature on knowledge management reveals, that this term is either used synonymously for information management or for the management of work practices with the goal to improve the generation of new knowledge and the sharing of existing knowledge. …”
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1140
Implementation Nutrigenomic of Vitamin D in Periodontitis
Published 2022-07-01“…The anti-microbial effect of vitamin D results from the binding of 1,25(OH)2D3 with VDR which then induces cAMP, b-def-2 and b-def-3 peptides by macrophages, monocytes, gingival epithelium and periodontal ligament epithelium. …”
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