An analysis of trends in the burden of ischemic stroke caused by air pollution in China between 1990 and 2021 by Zhengfeng Yu, Xiuyun Zhang, Xiaomei Fu, Xuemin Jia, Mingyan Ju, Yuxuan Zhang, Yuying Li, Ying Yin, Fanjie Liu

“…To assess historical trends and project disease burden from 2022 to 2036, Joinpoint regression modeling and decomposition analysis were employed. …”
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Numerical Prediction of Fatigue Life for Landing Gear Considering the Shock Absorber Travel by Haihong Tang, Panglun Liu, Jianbin Ding, Jinsong Cheng, Yiyao Jiang, Bingyan Jiang

“…On the basis of the whole geometric model of a large passenger aircraft’s main landing gear (MLG), the quasi-static finite element model (FEM) of the whole MLG is established, and the high-cycle fatigue issue of the Main Fitting (MF) is studied by considering the variation in shock absorber travel (SAT). …”
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Evolution of the burden of disease for high BMI-associated colorectal cancer, 1990–2021: Global trends, regional heterogeneity, and population risk stratification by Guangyi zhu, Yilan Sun, Dongbo Lian, Buhe Amin, Guangzhong Xu, Jing Wang, Nengwei Zhang, Dezhong Wang

“…Calculated estimated annual percentage change (EAPC) for trends. Demographic decomposition models quantified the contributions of population aging, epidemiological changes, and growth. …”
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Novel insights into the kinetics, bio-based chemicals and mechanisms for tobacco industry waste pyrolysis by Xing Fan, Boyu Li, Yu Xi, Junping Bian, Wenhua Zi

“…The kinetics of the devolatilisation stage were determined using isoconversional methods, and the potential of TIW as a bio-based chemical feedstock was evaluated. …”
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The Burden of Esophageal Cancer in Five East Asian Countries From 1990 to 2021 and Its Prediction Until 2036: An Analysis of the Global Burden of Diseases Study 2021 by Tianhao Guo, Yumo Yuan, Tingting Zhou, Yifan Hui, Yuhan Wang, Wenjian Zhu, Weixing Shen, Liu Li, Yu Yang, Haibo Cheng

“…The epidemiological characteristics of EC were analyzed by joinpoint regression, age‐period‐cohort analysis, and decomposition analysis. The burden of EC until 2036 was estimated using autoregressive integrated moving average and Bayesian age‐period‐cohort models. …”
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Divergent trajectories in pancreatic cancer burden among older adults (55+): a GBD 2021 analysis revealing China’s dual epidemic of aging and population growth (1990–2045) by Hui Dong, Heng Wang, Wenping Han, Haigang Niu

“…Joinpoint regression identified temporal trends (1990–2021), while Bayesian Age-Period-Cohort (BAPC) modeling projected future burden. Socioeconomic disparities were assessed via the Socio-demographic Index (SDI), and risk factor contributions were quantified using decomposition analysis.ResultsIn 2021, Finland, Germany, and Japan exhibited the highest age-standardized PC prevalence (ASPR: 64.42–66.17 per 100,000 population), contrasting sharply with Mozambique (ASPR: 2.85 per 100,000 population). …”
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Global, Regional, and National Burden of Breast Cancer, 1990–2021, and Projections to 2050: A Systematic Analysis of the Global Burden of Disease Study 2021 by Tong Deng, Hao Zi, Xing‐Pei Guo, Li‐Sha Luo, Ya‐Long Yang, Jin‐Xuan Hou, Rui Zhou, Qian‐Qian Yuan, Qing Liu, Qiao Huang, Gao‐Song Wu

“…ABSTRACT Background This study analyzes the global burden of breast cancer (BC) over the past 30 years, identifies key risk factors, and projects future incidence and mortality through 2050. Methods Data were sourced from the 2021 Global Burden of Disease (GBD) database. …”
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Association of prior tuberculosis with cardiovascular status in perinatally HIV-1-infected adolescents by Mpiko Ntsekhe, Landon Myer, Ntobeko Ntusi, Heather Zar, Emma Carkeek, Katalin A Wilkinson, Robert J Wilkinson, Jennifer Jao, Itai M Magodoro, Carlos Eduardo Guerrero-Chalela, Nana Akua Asafu-Agyei, Nomawethu Jele, Lisa J Frigati

“…Ventriculoarterial coupling (VAC) was estimated as the ratio of arterial elastance (Ea) to ventricular end-systolic elastance (Ees). Regression models were applied to estimate cross-sectional associations between Ea/Ees ratio and TB status, with decomposition of these associations into direct and mediated effects of hsCRP, FPG and dyslipidaemia, if any, attempted.Results We enrolled 43 APHIV with prior TB and 23 without TB of mean (SD) age 15.0 (1.5) and 15.4 (1.7) years, respectively. …”
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Vascular-related biological stress, DNA methylation, allostatic load and domain-specific cognition: an integrated machine learning and causal inference approach by Reem Waziry, Olajide A Williams, Henning Tiemeier, Caleb Miles

“…Four-way decomposition modeling approach was used to calculate the natural direct and indirect effects in the relationship between vascular disease and major cognitive domains. …”
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Mineralogy and sulfide mineral chemistry of Khabr iron ore, Southwest of Baft (Southeast of Sanandaj-Sirjan Zone) by Mohammad Boomeri, Habib Biabangard, Somayeh Dehghani Soltani, Azadeh Bordbar

“…The sulfide minerals are analyzed by the Electron Probe Micro Analyze (EPMA) model of JEOL. JXA-8600 with an accelerator voltage of 15kv and current of 2×10-8 A in Yamagata University.  …”
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Discovery of Novel CRK12 Inhibitors for the Treatment of Human African Trypanosomiasis: An Integrated Computational and Experimental Approach by Qin Li, Jiayi Luo, Chenggong Fu, Wenqingqing Kang, Lingling Wang, Henry Tong, Zhaorong Lun, Qianqian Zhang, Dehua Lai, Huanxiang Liu

“…Cell division cycle-2-related kinase 12 (CRK12), a pivotal protein involved in the cell cycle regulation of <i>T. brucei</i>, has emerged as a promising therapeutic target for HAT, yet effective CRK12 inhibitors remain lacking. <b>Methods:</b> An integrated strategy combining computational modeling, virtual screening, molecular dynamics (MD) simulations, and experimental validation was adopted to discover potential inhibitors against CRK12. …”
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Polydopamine Nanoparticle-Integrated Smart Bletilla striata Polysaccharide Hydrogel: Photothermal-Triggered CO2 Release for Diabetic Wound Microenvironment Modulation by Wang X, Ma Z, He Y, Sun Y, Peng Q, Zhao M, Huang X, Lei L, Gu H, Gou K, Zeng R

“…The improvement effect of CO2@PDA Hydrogel on the diabetes wound microenvironment was comprehensively evaluated by promoting L929 cell proliferation, inhibiting bacterial growth (Staphylococcus aureus and Escherichia coli), and treating diabetes wound infection in rat models.Results: Under 808 nm near-infrared laser irradiation, the embedded CO2@PDA NPs convert light into heat, triggering the decomposition of HCO3− and releasing a substantial amount of CO2 locally at the diabetic wound site. …”
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Association Between Visual Acuity and Incident Atherosclerotic Cardiovascular Disease: A Longitudinal Test of Mediators by Zijing Du, Xiayin Zhang, Gabriella Bulloch, Feng Zhang, Yu Huang, Yaxin Wang, Yingying Liang, Guanrong Wu, Zhuoting Zhu, Xianwen Shang, Yijun Hu, Xiaohong Yang, Honghua Yu

“…The longitudinal association between VA and ASCVD was examined using Cox proportional hazards models. A four-way decomposition mediation analysis was performed to quantify the indirect effects of hypertension, diabetes, depression, and socioeconomic status in mediating the relationship between VA and ASCVD. …”
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Global burden and trends of high BMI-attributable chronic kidney disease: a comprehensive analysis from 1990 to 2021 and projections to 2035 by Huifang Tan, Zhifu Liu, Yongjie Zhang, Kehao Yang, Yiming Zeng, Guoli Li, Zheng Xiao, Yuanwei Li, Yinyin Chen

“…Age-standardized mortality rate (ASMR) and age-standardized disability-adjusted life years rate (ASDR) were assessed using percentage change (PC) and estimated annual percentage change (EAPC). Decomposition analysis quantified drivers of mortality and DALYs changes, while Bayesian age-period-cohort models projected future trends.FindingsFrom 1990 and 2021, the ASMR of CKD attributable to high BMI increased from 2.69 (95% UI: 1.37–4.14) to 5.06 (95% UI: 2.7–7.5) per 100,000, and the ASDR rose from 69.13 (95% UI: 35.06–106) to 122.08 (95% UI: 66.25–180.18) per 100,000. …”
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Inequities in the continuum of maternal care in Mexico: trends before and after COVID-19 by Edson Serván-Mori, Rocio Garcia-Diaz, Sergio Meneses-Navarro, Octavio Gómez-Dantés, Diego Cerecero-García, Arachu Castro, Rafael Lozano

“…We used multiple regression models to assess factors influencing the likelihood of receiving comprehensive antenatal care, skilled delivery care and postpartum care interventions, both pre-and post-COVID-19. …”
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Interpretable Multi-Sensor Fusion of Optical and SAR Data for GEDI-Based Canopy Height Mapping in Southeastern North Carolina by Chao Wang, Conghe Song, Todd A. Schroeder, Curtis E. Woodcock, Tamlin M. Pavelsky, Qianqian Han, Fangfang Yao

“…We evaluated four machine learning algorithms, K-nearest neighbors (KNN), random forest (RF), support vector machine (SVM), and eXtreme gradient boosting (XGB), and found consistent accuracy across all models. Our evaluation highlights our method’s robustness, evidenced by closely matched R² and RMSE values across models: KNN (R² of 0.496, RMSE of 5.13 m), RF (R² of 0.510, RMSE of 5.06 m), SVM (R² of 0.544, RMSE of 4.88 m), and XGB (R² of 0.548, RMSE of 4.85 m). …”
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Assessing spatial variability of soil macro fauna and tree canopy using fractal theory (Case study: Riparian Forest of Maroon River) by Shaieste Gholami, ehsan sayad, Hamid Taleshi

“…In spite of this, within spatial ecology, empirical and modeling studies have concentrated on aboveground biota, limiting belowground detail, if any, to abiotic properties of soil. …”
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Unraveling key environmental drivers of spatial variation in plant functional traits: Insights from Dacrydium pectinatum de Laub. in natural communities on Hainan Island, China by Haodong Liu, Gaoqiang Zhang, Tianqi Li, Siyuan Ren, Baihua Chen, Kaibin Feng, Shanshan Wang, Xiaoqing Zhao, Xingxing Rong, Pengyao Qin, Junpeng Zhao, Wei Li

“…Nine functional traits were measured at the species level, and their variation patterns and sources were analyzed using linear mixed-effects models and variance decomposition methods. Our findings reveal that environmental pressures cause variations in trait relationships across different site conditions at the species level. …”
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Integrating GIS and remote sensing for soil attributes mapping in degraded pastures of the Brazilian Cerrado by Rômullo Oliveira Louzada, Ivan Bergier, Édson Luis Bolfe, Jayme Garcia Arnal Barbedo

“…Results showed that Boruta-enhanced models (T2 + T4) improved performance in 89 % of cases. …”
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