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1901
Trends and predictions of the global burden of ischemic heart disease in women of childbearing age attribute to high body mass index and hypertension,1990–2021: a systematic analys...
Published 2025-05-01“…To assess the contribution of epidemiological changes, population growth, and population ageing, a decomposition analysis was used. Exponential Smoothing (ES) modeling and the Autoregressive Integrated Moving Average (ARIMA) model were used to predict the global ASDR (age-standardized DALYs rate), ASMR (age-standardized mortality rate) attributed to the 2 risk factors from 2022 to 2050. …”
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1902
Single-cell and spatial atlas of glioblastoma heterogeneity: characterizing the PCLAF+ subtype and YEATS4’s oncogenic role
Published 2025-07-01“…Therefore, multi-dimensional therapeutic strategies targeting GBM-specific molecular features, its intrinsic properties, and microenvironmental regulatory networks were considered to potentially provide new breakthroughs for overcoming treatment resistance in GBM.MethodsWe analyzed single-cell RNA sequencing (scRNA-seq) data processed with the Seurat package to accurately identify cell types. …”
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1903
A Hybrid STL-Deep Learning Framework for Behavioral-Based Intrusion Detection in IoT Environments
Published 2025-06-01“…Effective intrusion detection systems (IDSs) are crucial for securing IoT environments, requiring high detection accuracy while efficiently handling large data volumes and critically minimizing both false negatives (FNR), which miss real attacks, and false positives (FPR), which cause unnecessary alarms. Traditional methods and standalone deep learning models often struggle to achieve an optimal balance between these requirements. …”
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1904
Global burden and trends of musculoskeletal disorders in postmenopausal elderly women: a 1990–2021 analysis with projections to 2045
Published 2025-06-01“…Bayesian Age-Period-Cohort (BAPC) models projected trends to 2045. Health inequalities were analyzed using the Slope Index of Inequality (SII) and the Concentration Index, with decomposition methods identifying the drivers of burden changes. …”
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1905
An analysis of trends in the burden of ischemic stroke caused by air pollution in China between 1990 and 2021
Published 2025-04-01“…To assess historical trends and project disease burden from 2022 to 2036, Joinpoint regression modeling and decomposition analysis were employed. …”
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1906
Global, Regional, and National Temporal Trends in Incidence for Type 2 Diabetes Mellitus Related Chronic Kidney Disease from 1992 to 2021
Published 2025-07-01“…The impact of macro-factors (demographic change, age, period, and birth cohort) on CKD-T2DM incidence trends was assessed using decomposition analyses and age-period-cohort modeling, highlighting opportunities to improve incidence and reduce regional disparities. …”
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1907
Global, regional and country burden of high BMI-related liver cancer among individuals aged above 70: trends from 1990 to 2021 and projections to 2044
Published 2025-03-01“…Joinpoint regression and age-period-cohort models were used to analyze DALY trends and demographic influences, and decomposition analysis assessed the effects of population aging, growth, and epidemiological shifts.ResultsOur findings revealed significant geographical disparities in HB-LC mortality, with East Asia, Southeast Asia, and parts of West Africa showing the highest rates. …”
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1908
Effects of Short-Term Straw Return and Manure Fertilization on Soil Microorganisms and Soybean Yield in Parent Material of Degraded Black Soil in Northeast China
Published 2025-05-01“…This study provides scientific methods to improve the fertility of degraded black soil and increase soybean production in the short term.…”
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1909
Global trends in chronic kidney disease mortality and disability-adjusted life years attributable to low physical activity (1990–2021): a growing public health challenge
Published 2025-04-01“…This study focused on trends from 1990 to 2021 across the globe, China, five SDI regions, and four continents. Decomposition analysis, frontier analysis, and forecasting models were employed to explore changes in these indicators and their influencing factors. …”
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1910
Global, regional, and national burden of tuberculosis due to smoking, 1990-2021: analysis for the Global Burden of Disease study
Published 2025-07-01“…Recent studies have shown that smoking is an important risk factor for the development of TB and advances the progression of TB through multiple mechanisms that affect the body’s immune function.MethodsA multidimensional analytical approach was taken to gain a comprehensive understanding of the burden of disease. …”
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1911
Global burden and health inequality of atrial fibrillation/atrial flutter from 1990 to 2021
Published 2025-05-01“…Age-standardized rates were calculated at global, regional, and country-specific levels. Decomposition and Bayesian age-period-cohort models were used to explore trends and forecast future disease burdens.ResultsIn 2021, AF/AFL contributed to 4.48 million new cases globally, with an age-standardized incidence rate (ASIR) of 52.1 per 100,000. …”
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1912
Global, regional, and national esophageal cancer deaths and DALYs attributable to diet low in vegetables and fruits, 1990–2019: analysis for the global burden of disease study
Published 2025-01-01“…BackgroundThis study aimed to comprehensively assess the global, regional, and national burden of esophageal cancer (EC) attributable to inadequate vegetable and fruit intake from 1990 to 2019 and explore the potential impact of existing dietary intervention programs on EC prevention.MethodsUsing the Global Burden of Disease Study 2019 (GBD 2019) database, we conducted descriptive analyses stratified by age, sex, Socio-demographic Index (SDI), and regional levels. …”
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1913
Global, regional, and national burden of uterine cancer among women aged 50 years and older from 1990 to 2021: a systematic analysis for the global burden of disease study 2021
Published 2025-06-01“…This study aimed to evaluate its disease burden across regions and nations. Methods Using Global Burden of Disease 2021 data, we analyzed the incidence, mortality, disability-adjusted life years (DALYs), and trends via estimated annual percentage change (EAPC), decomposition, inequality analyses, and Bayesian Age-Period-Cohort modeling for 2022–2040 projections. …”
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1914
The influence of social class of origin on labor market entry and the mediating role of education in Italy
Published 2025-06-01“…This study aims to analyze how social origin influences transition to the first job across different birth cohorts, gender groups, and macro-region of residence while also assessing the mediating role of education.MethodsUsing Event History Analysis, we estimate labor market entry timing via survival models and discrete-time logistic regression, accounting for social background effects. …”
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1915
Taphonomy and whale-fall analysis of the Tortonian baleen whales from the Stirone river, Emilia Romagna (northern Italy)
Published 2025-04-01“…The diversity of the trace fossils and the broad stratigraphic context in which the assemblages are included are investigated in order to investigate into the origin and evolution of the specialized whale fall communities since the Neogene.MethodsMacrophotographs, three-dimensional modeling from photogrammetry and laser scanner examinations of the specimens were used to analyze the diversity of trace fossils observed on the bones of the balaenopterids. …”
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1916
Global, regional, and national burden of idiopathic epilepsy in older adults, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021
Published 2025-07-01“…Additionally, we performed a decomposition analysis to determine the contributions of population growth, aging, and epidemiological changes, and used Bayesian age-period-cohort (BAPC) modeling to project future burden through 2035. …”
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1917
Psychosocial determinants of adherence to public health and social measures (PHSMs) in 18 African Union Member States during the early phase of the COVID-19 pandemic: results of a...
Published 2022-06-01“…Factors affecting adherence were ranked using the Shapley regression decomposition method.Results Adherence to PHSMs was high, with better adherence to personal than community PHSMs (65.5% vs 30.2%, p<0.05). …”
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1918
The influence of compost humic acid quality and its ability to alleviate soil salinity stress
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1919
Global burden, temporal trends, and health workforce correlations of gallbladder and biliary tract cancer: a comprehensive analysis from 1990 to 2021 with projections to 2046
Published 2025-08-01“…Advanced statistical approaches included age-period-cohort modeling, decomposition analysis, health inequality assessment, frontier analysis, and novel correlations between 22 health workforce categories and disease burden. …”
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1920
Evolution of the burden of disease for high BMI-associated colorectal cancer, 1990–2021: Global trends, regional heterogeneity, and population risk stratification
Published 2025-09-01“…Calculated estimated annual percentage change (EAPC) for trends. Demographic decomposition models quantified the contributions of population aging, epidemiological changes, and growth. …”
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