RNA mis‐splicing in children with congenital myotonic dystrophy is associated with physical function by Julia M. Hartman, Kobe Ikegami, Marina Provenzano, Kameron Bates, Amanda Butler, Aileen S. Jones, Kiera N. Berggren, Jeanne Dekdebrun, Marnee J. McKay, Jennifer N. Baldwin, Kayla M. D. Cornett, Joshua Burns, Michael Kiefer, Nicholas E. Johnson, Melissa A. Hale, the DMCRN Consortium

“…The strength of these correlations and the development of predictive models will assist in designing efficacious clinical trials for individuals with DM1, particularly CDM.…”
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Predicting Transvaginal Surgical Mesh Exposure Outcomes Using an Integrated Dataset of Blood Cytokine Levels and Medical Record Data: Machine Learning Approach by Mihyun Lim Waugh, Tyler Mills, Nicholas Boltin, Lauren Wolf, Patti Parker, Ronnie Horner, Thomas L Wheeler II, Richard L Goodwin, Melissa A Moss

“…ConclusionsSupervised machine learning models demonstrated improved prediction accuracy when trained using a composite dataset that combined patient medical record data and biomaterial-induced blood cytokine levels, surpassing the performance of models trained with either dataset in isolation. …”
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Preparation of Magnetic Photocatalyst Fe₃O₄@SiO₂@Fe-TiO₂ and Photocatalytic Degradation Performance of Methyl Orange in Na₂SO... by Li Sun, Zilong Li, Zhigang Yuan, Ying Liu, Shunqi Mei, Fanhe Meng, Xingyu Ouyang, Yi Xiong, Ke Zhang, Zhen Chen

“…In this study, Fe₃O₄@SiO₂@TiO₂ (FS-FT (0 g)) photocatalysts, featuring a magnetic core–shell structure, and Fe-doped Fe₃O₄@SiO₂@Fe-TiO₂ (FS-FT (x g)) photocatalysts, were fabricated via the sol–gel method. Structural and compositional analyses of the processed samples were systematically conducted through X-ray diffraction (XRD), transmission electron microscopy (TEM) with selected area electron diffraction (SAED), surface-sensitive X-ray photoelectron spectroscopy (XPS), and optical property assessment via UV-Vis diffuse reflectance spectroscopy (UV-DRS). …”
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Nutritional status and systemic inflammation in COPD: prognostic value of the advanced lung cancer inflammation index by Jun Yao, Peng Wu, Zhishu Li, Lingyan Zhao, Ziqiao Fu, Ping Shi, Xiaomin Xiong, Xuping Chen, Bin Yu, Yan He, Tong Feng, Jia Zeng, Ran Duan, Ran Duan

“…Survival analyses, including Kaplan–Meier curves, Cox proportional hazards models, and restricted cubic splines, were used to assess the association between ALI and mortality outcomes, exploring non-linear trends and thresholds.ResultsHigher ALI levels were significantly associated with reduced risks of all-cause and cardiovascular mortality in COPD patients. …”
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Interplay between worsening kidney function and cardiovascular events in patients with type 2 diabetes: an analysis from the ACCORD trial by João Pedro Ferreira, Patrick Rossignol, Faiez Zannad, Abhinav Sharma, Diana Ferrao, Francisco Vasques-Novoa, Adelino Leite-Moreira

“…We have used a large population of patients with T2D and a high cardiovascular risk enrolled in the Action to Control Cardiovascular Risk in Diabetes Study.Research design and methods Time-updated, joint, and multistate modeling were used. …”
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Relationship between kidney function and healthy life expectancy: A historical cohort study by Hisayuki Ogura, Tadashi Toyama, Hikaru Samuta, Kohei Hirako, Tomoya Itatani, Shiori Nakagawa, Megumi Oshima, Shinji Kitajima, Akinori Hara, Norihiko Sakai, Miho Shimizu, Tomoyuki Takura, Takashi Wada, Yasunori Iwata

“…The primary endpoint was a composite of becoming a care level ≥ 2 or death. Multivariable Cox proportional hazards models were used to calculate the risk regarding time to the primary endpoint. …”
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Associations of frailty and cognitive impairment with all-cause and cardiovascular mortality in older adults: a prospective cohort study from NHANES 2011–2014 by An-Bang Liu, Yan-Xia Lin, Guan-Ying Li, Ting-Ting Meng, Peng Tian, Jian-Lin Chen, Xin-He Zhang, Wei-Hong Xu, Yu Zhang, Dan Zhang, Yan Zheng

“…Frailty was quantified using a 49-item frailty index, while pMCI was determined by three composite cognition scores one standard deviation (SD) below the mean. …”
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Reduced sensitivity to thyroid hormones is associated with differentiated thyroid cancer in the euthyroid thyroidectomy population by Huaijin Xu, Huaijin Xu, Hongzhou Liu, Xiaodong Hu, Xiaomeng Jia, Zhe Xue, Anning Wang, Shaoyang Kang, Shaoyang Kang, Zhaohui Lyu, Zhaohui Lyu

“…BackgroundThe inconclusive associations between thyroid-related hormones and differentiated thyroid cancer (DTC) suggest complex pathophysiologic processes, for which thyroid hormone sensitivity may provide new insights.MethodsWe retrospectively analyzed preoperative clinical data and postoperative pathological data of 9,515 euthyroid adults who underwent thyroidectomy for thyroid nodules pathologically confirmed as benign nodules or DTC. …”
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Intraoperative hemodynamics in prediction of postoperative kidney injury after type a aortic dissection surgery: a retrospective cohort study by Lihai Chen, Yi Cheng, Xinyi Bu, Chen Zhang, Jie Sun, Xuesheng Liu, Siyu Kong, Yali Ge, Hongwei Shi, Jifang Zhou

“…Secondary outcomes included death, stroke and composite outcome. Patients were divided into four groups: AKI only, AKD only, AKI and AKD, Non-AKI or AKD. …”
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Physical activity and mortality in the general population with and without major depression by Vagner Deuel de O. Tavares, Jeanne V. A. Williams, Vandad Sharifi, Andrew Bulloch, Gina Dimitropoulos, Nicole Leite Galvão-Coelho, Scott Patten

“…Major depression was assessed using a fully structured diagnostic instrument, the Composite International Diagnostic Interview. Mortality data was obtained through data linkage. …”
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A comprehensive review of silicon anodes for high-energy lithium-ion batteries: Challenges, latest developments, and perspectives by Ebrahim Feyzi, Anil Kumar M R, Xia Li, Sixu Deng, Jagjit Nanda, Karim Zaghib

“…Furthermore, the review discusses innovative solutions to address these challenges, such as utilizing novel binders, electrolyte additives, structural, interfacial, composite engineering techniques, and prelithiation methods. …”
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Sex Differences in the Association Between Lipoprotein(a) and Cardiovascular Outcomes: The MGB Lp(a) Registry by Gurleen Kaur, Adam N. Berman, David W. Biery, Stephanie A. Besser, Wanda Y. Wu, Brittany Weber, Michael C. Honigberg, Khurram Nasir, Martha Gulati, Marcelo F. Di Carli, Leslee J. Shaw, Deepak L. Bhatt, Ron Blankstein

“…Cox proportional hazard modeling was used to assess the association of lipoprotein(a) with the primary outcome. …”
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The temporal onset of associations of cortical proteins with cognitive resilience vary during late life by Andrea R. Zammit, Tianhao Wang, Lei Yu, Shahram Oveisgharan, Vladislav A. Petyuk, Philip L. De Jager, Julie A. Schneider, David A. Bennett, Aron S. Buchman

“…Cognition was assessed using a composite derived from 19 tests. We first used linear mixed-effects models to identify cortical proteins associated with cognitive resilience. …”
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Land use change has profoundly altered the process of bacterial community assembly in the northeastern black soil zone by Ning Sun, Xu Zhao, Xu Zhao, Fangyuan Liu, Fangyuan Liu, Ge Song, Mengmeng Zhang, Fuqiang Song

“…Using random forest classification modeling, we identified several rare bacterial genera, including Rhodomicrobium, Amycolatopsis, and Clostridium, which, despite each representing less than 1% of the community, played critical roles in shaping microbial community structure. …”
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Healthy lifestyle factors and combined macrovascular and microvascular events in diabetes patients with high cardiovascular risk: results from ADVANCE by Shoujiang You, Danni Zheng, Yanan Wang, Qiang Li, Tu N. Nguyen, Ruth Peters, Xiaoying Chen, Xia Wang, Yongjun Cao, Diederick E. Grobbee, Stephen Harrap, Giuseppe Mancia, Bryan Williams, Neil R. Poulter, Liu Lisheng, Michel Marre, Pavel Hamet, Craig S. Anderson, Mark Woodward, John Chalmers, Katie Harris

“…Multivariable Cox models were used to determine associations of 0, 1, 2, and ≥ 3 HLFs with vascular events and all-cause mortality. …”
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Plasma microRNA signatures of aging and their links to health outcomes and mortality: findings from a population-based cohort study by Lieke M. Kuiper, Michelle M. J. Mens, Julia W. Wu, Jaap Goudsmit, Yuan Ma, Liming Liang, Albert Hofman, Trudy Voortman, M. Arfan Ikram, Jeroen G. J. van Rooij, Joyce B. J. van Meurs, Mohsen Ghanbari

“…Next, elastic net models were employed to construct composite microRNA-based aging biomarkers predicting chronological age (mirAge), PhenoAge (mirPA), frailty index (mirFI), and mortality (mirMort). …”
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Association between energy intake and prognosis in Chronic Kidney Disease (CKD) stages 3–5: an ambispective cohort study by Di Yang, Huifen Chen, Yan Han, Yuhan Shen, Guixin Liang, Tao Zhou, Fang Tang, Lizhe Fu, Yifan Wu, Meizhu Ding

“…Kaplan–Meier analysis, restricted cubic splines, and Cox regression models were performed to assess the association.Results 85 (36.3%) individuals reached the endpoint with a median follow-up of 33 months. …”
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Effects of School‐Based Lifestyle Interventions on Cardiovascular Health in Chinese Children and Adolescents: A Post Hoc Analysis of a National Multicenter Study by Pengfei Guo, Yueqin Zhou, Zhiyong Zou, Yajun Chen, Jin Jing, Yinghua Ma, Yi Song, Wenhua Ling, Jun Ma, Yanna Zhu

“…The primary outcomes were these 3 composite scores and high CVH (CVH score≥80). All analyses applied a likelihood‐based random‐effects regression modeling following the intention‐to‐treat. …”
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Efficacy of a Blended Low-Intensity Internet-Delivered Psychological Program in Patients With Multimorbidity in Primary Care: Randomized Controlled Trial by Alicia Monreal-Bartolomé, Adoración Castro, M Ángeles Pérez-Ara, Margalida Gili, Fermín Mayoral, María Magdalena Hurtado, Esperanza Varela Moreno, Cristina Botella, Azucena García-Palacios, Rosa M Baños, Yolanda López-Del-Hoyo, Javier García-Campayo, Jesus Montero-Marin

“…Differences between the groups were estimated using mixed effects linear regression models, and mediation evaluations were conducted using path analyses to evaluate the potential mechanistic role of positive and negative affectivity and openness to the future. …”
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Relationship Among Macronutrients, Dietary Components, and Objective Sleep Variables Measured by Smartphone Apps: Real-World Cross-Sectional Study by Jaehoon Seol, Masao Iwagami, Megane Christiane Tawylum Kayamare, Masashi Yanagisawa

“…Models were adjusted for age, sex, and BMI. …”
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