A blood‐based nutritional risk index explains cognitive enhancement and decline in the multidomain Alzheimer prevention trial by Gene L. Bowman, Hiroko H. Dodge, Sophie Guyonnet, Nina Zhou, Juliana Donohue, Aline Bichsel, Jeroen Schmitt, Claudie Hooper, Tamas Bartfai, Sandrine Andrieu, Bruno Vellas, MAPT/DSA Study Group, Bruno Vellas, Sophie Guyonnet, Isabelle Carrié, Lauréane Brigitte, Catherine Faisant, Françoise Lala, Julien Delrieu, Hélène Villars, Emeline Combrouze, Carole Badufle, Audrey Zueras, Sandrine Andrieu, Christelle Cantet, Christophe Morin, Gabor Abellan Van Kan, Charlotte Dupuy, Yves Rolland, Céline Caillaud, Pierre‐Jean Ousset, Françoise Lala

“…The primary outcome in MAPT was a cognitive composite Z score within each participant that was fit with linear mixed‐effects models. …”
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Protocol for an observational study to assess the impact of pharmacogenetics on outcomes in vascular surgery (PROSPER) by John H McDermott, William G Newman, Stuart Wright, Kerry Anne Burke, Selman Mirza, Nicholas S Greaves

“…Secondary outcomes are risk of MALE at 1 year, risk of major adverse cardiovascular events (MACE) or death from any cause at 1 year, death within 30 days of revascularisation, minor re-interventions at 1 year, total number of re-interventions at 1 year and rate of systemic or gastrointestinal bleed at 1 year.Risk of amputation, MALE and MACE will be analysed using Cox models. All remaining outcomes will be analysed using negative binomial models. …”
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IL-17A Levels and Progression of Kidney Disease Following Hospitalization with and without Acute Kidney Injury by Jason A. Collett, Alexander H. Flannery, Lucas J. Liu, Tomonori Takeuchi, David P. Basile, Javier A. Neyra

“…In adjusted multivariable models, IL-17A levels were not independently associated with progression of kidney disease. …”
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Association of urbanization-related factors with tuberculosis incidence among 1992 counties in China from 2005 to 2019: a nationwide observational study by Yaping Wang, Xiaoqiu Liu, Yuhong Li, Min Liu, Yiheng Wang, Hongliang Zhang, Jue Liu, Yanlin Zhao

“…We aimed to assess the association between urbanization factors and TB incidence in China. Methods We evaluated urbanization at the county level in China from 2005 to 2019 using a composite index integrating population density, gross domestic product (GDP, per capita), hospital beds per 1000 population, nighttime light (NTL), and normalized difference vegetation index (NDVI). …”
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Iranian university students’ alcohol-related knowledge, attitude, and practice questionnaire (ISKAP alcohol Q): development and psychometric properties by Mahsa Janati, Nouzar Nakhaee, Ali Karamoozian, Somayeh Alizadeh, Mostafa Yazdani, Hamid Sharifi, Abedin Iranpour

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Association between lower geriatric nutritional risk index and low cognitive functions in United States older adults: a cross-sectional study by Jiuling Liu, Melysze Deanne Oorloff, Adithya Nadella, Ning Zhou, Min Ye, Yifeng Tang, Yuanwei Wang

“…Weighted multiple logistic regression models were used to evaluate the association between GNRI and cognitive function. …”
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Optimal timing of anticoagulation after acute ischaemic stroke with atrial fibrillation (OPTIMAS): statistical analysis plan for a randomised controlled trial by Norin Ahmed, Hakim-Moulay Dehbi, Nick Freemantle, Jonathan Best, Philip S. Nash, James K. Ruffle, David Doig, David J. Werring

“…Here, we describe in detail the statistical aspects of OPTIMAS, including outcome measures, sample size calculation, general analysis principles, descriptive statistics, statistical models, and planned subgroup analyses. Study outcomes The primary outcome is a composite of recurrent stroke (ischaemic stroke or symptomatic intracranial haemorrhage) and systemic arterial embolism within 90 days. …”
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Advances and trends of non-marine shale sedimentology: A case study from Gulong Shale of Daqing Oilfield, Songliao Basin, NE China by Longde SUN, Rukai ZHU, Tianshu ZHANG, Yi CAI, Zihui FENG, Bin BAI, Hang JIANG, Bo WANG

“…Such research will focus on eight aspects: lithofacies and organic matter distribution prediction under a sequence stratigraphic framework for non-marine shale strata; lithofacies paleogeography of shale strata based on the forward modeling of sedimentation; origins of non-marine shale lamina and log-based identification of lamina combinations; source of organic matter in shale and its enrichment process; non-marine shale lithofacies classification by rigid particles + plastic components + pore-fracture system; multi-field coupling organic-inorganic interaction mechanism in shale diagenesis; new methods and intelligent core technology for shale reservoir multi-scale characterization; and quantitative evaluation and intelligent analysis system of shale reservoir heterogeneity.…”
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Longitudinal Lipid Trajectories and Progression of CKD in Children by Uwe Querfeld, Marietta Kirchner, Francesca Mencarelli, Karolis Azukaitis, Aysun Bayazit, Ali Duzova, Anke Doyon, Nur Canpolat, Ipek Kaplan Bulut, Lukasz Obrycki, Justine Bacchetta, Rukshana Shroff, Dusan Paripovic, Cengiz Candan, Jerome Harambat, Alev Yilmaz, Harika Alpay, Jun Oh, Hakan Erdogan, Claus P. Schmitt, Anette Melk, Franz Schaefer

“…By semiparametric group-based trajectory modeling (GBTM), 2 trajectories were defined for each lipid, termed “high” and “low.” …”
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Hydrophilic and superoleophobic GO-TiO2 PVDF/PEI membrane with antifouling properties for efficient oil-water separation by Mitushi Agrawal, Triparna Chakraborty, Dharmveer Yadav, Sumit Saxena, Shobha Shukla

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Computerized cognitive testing to capture cognitive decline in Alzheimer's disease: Longitudinal findings from the ARMADA study by Roos J. Jutten, Emily H. Ho, Tatiana Karpouzian‐Rogers, Carol van Hulle, Cynthia Carlsson, Hiroko H. Dodge, Cindy J. Nowinski, Richard Gershon, Sandra Weintraub, Dorene M. Rentz

“…Linear mixed‐effect models correcting for demographics were used to examine cross‐sectional and longitudinal NIHTB‐CB scores in individuals across the clinical AD spectrum. …”
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Acceptability of a 250 mg levofloxacin formulation in children receiving TB preventive treatment by S.E. Purchase, J. Brigden, J.A. Seddon, N.A. Martinson, L. Fairlie, S. Staples, A. Poswa, T. Duong, H.S. Schaaf, A.C. Hesseling

“…Likert scales were used to grade 6 domains of acceptability, and a composite acceptability (CA) outcome was generated. …”
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Burden of Coronary Artery Disease as a Predictor of New Vascular Events and Mortality in Patients With Ischemic Stroke: Insights From the Norwegian Stroke in the Young Study by Khuluud Abdi Jibril, Kier Jan Kuiper, Beenish Nawaz, Halvor Naess, Annette Fromm, Halvor Øygarden, Kristin Modalsli Sand, Rudy Meijer, Abukar Mohamed Ali, Terje H. Larsen, Øyvind Bleie, Elisabeth Skaar, Ulrike Waje‐Andreassen, Sahrai Saeed

“…In the multivariable Cox regression models, CAD was a strong and independent predictor of all‐cause mortality (hazard ratio [HR], 2.20 [95% CI, 1.05–4.60]; P=0.037) and the composite end point of death or recurrent ischemic stroke (HR, 3.24 [95% CI, 1.46–7.20]; P=0.004). …”
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Social Vulnerability and Long‐Term Cardiovascular Outcomes After COVID‐19 Hospitalization: An Analysis of the American Heart Association COVID‐19 Registry Linked With Medicare Clai... by Reza Fakhraei, Yang Song, Dhruv S. Kazi, Rishi K. Wadhera, James A. de Lemos, Sandeep R. Das, David A. Morrow, Issa J. Dahabreh, Christine M. Rutan, Kathie Thomas, Robert W. Yeh

“…We evaluated the association between social vulnerability and a composite of myocardial infarction, stroke, heart failure, venous thromboembolism, cardiogenic shock, cardiac arrest, and death, following discharge, using Cox regression models. …”
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Prognostic Value of Biomarkers in Cancer Patients Treated With Immune Checkpoint Inhibitor Therapy by Christopher Mann, MD, Ulrike Pailer, MSc, Andreas Spannbauer, MD, Fardin Hamidi, MD, Aliza Veronika Braser, Martin Hülsmann, MD, Christian Gerges, MD, PhD, Michael Gottsauner-Wolf, MD, Mariann Gyöngyösi, MD, Markus Raderer, MD, Martin Riesenhuber, MD, PhD, Christian Hengstenberg, MD, Jutta Bergler-Klein, MD, Thomas A. Zelniker, MD, MSc

“…The primary outcome of interest was the composite of acute cardiovascular hospitalization heart failure or death. …”
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From fragmented to integrated: Advancing surface water quality assessment through WQPI in the upper Medjerda River, Northeastern Algeria by Benacherine Mostefa, Lyazid Mohamed Nadjib, Allaoua Noua, Soualah Alila Hana, Satour Abd El Latif, Chouiter Norhane, Debassi Bouchra, Zineb Chetouh, Md Galal Uddin

“…In this study, we evaluated the surface water quality of the upper Medjerda River in northeastern Algeria by integrating traditional indices, the Organic Pollution Index (OPI) and the Weighted Arithmetic Water Quality Index (WA_WQI), with advanced multivariate analyses including Principal Component Analysis (PCA) and Generalized Linear Models (GLMs). To overcome the limitations of conventional methods, we developed a new composite metric, the Water Quality Pollution Index (WQPI), synthesizing both general physicochemical conditions and organic pollution. …”
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Tocilizumab modulates the activity of the classical and alternative complement pathways in rheumatoid arthritis patients by Iván Ferraz-Amaro, Iván Ferraz-Amaro, Sergio Santos-Concepción, Javier Castro-Hernández, Maria Vanesa Hernández-Hernández, Beatriz Tejera Segura, Cristina Luna, Esmeralda Delgado-Frias, Federico Díaz-González, Federico Díaz-González, Federico Díaz-González

“…Multivariable linear mixed models were used to determine changes in the complement system cascades over time.ResultsAfter adjustment for disease activity, basal levels of the classical and alternative pathways decreased significantly after TCZ treatment. …”
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Control Indicators for Typical Persistent Organic Pollutants in Lake Sediments by LUO Xi, XIE Xiao-jing, XU Cheng-jian, ZHANG Lu, YAN Dan, TANG Qiang

“…[Objective] Focusing on the composite-polluted sediments of Ya’er Lake in the Yangtze River Basin, this study aims to address the lack of control indicators for persistent organic pollutants (POPs) in environmental dredging projects. …”
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TreatmENT of AnastomotiC LeakagE after colon cancer resection: the TENTACLE – Colon study by Jobbe M. G. Lemmens, Sander Ubels, Nynke G. Greijdanus, Kiedo Wienholts, Marleen M. H. J. van Gelder, Albert Wolthuis, Jérémie H. Lefevre, Kilian Brown, Matteo Frasson, Nicolas Rotholtz, Quentin Denost, Rodrigo O. Perez, Tsuyoshi Konishi, Martin Rutegård, Susan L. Gearhart, Thomas Pinkney, Muhammed Elhadi, Roel Hompes, Pieter J. Tanis, Johannes H. W. de Wilt

“…Methods The TENTACLE – Colon is an international multicentre retrospective cohort study. …”
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Heterogeneous Effects of Intensive Glycemic and Blood Pressure on Cardiovascular Events Among Diabetes by Living Arrangements by Kanta Kiyohara, Naoki Kondo, Taku Iwami, Yuichiro Yano, Akira Nishiyama, Koichi Node, Nobuya Inagaki, O. Kenrik Duru, Kosuke Inoue

“…Cox proportional hazard models were used to estimate the joint effect of intensive glycemic and BP control on the composite cardiovascular outcome according to living arrangements. …”
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