Total and regional fat-to-muscle mass ratio and risks of pan-cancer: a prospective cohort study by Ruizhi Wang, Yudi Xu, Yuyuan Zhang, Yushuai Wu, Anning Zuo, Shutong Liu, Yuhao Ba, Hui Xu, Siyuan Weng, Zhaokai Zhou, Hongxuan Ma, Peng Luo, Quan Cheng, Xinwei Han, Zaoqu Liu

“…Multivariable Cox proportional hazards models, along with Cox models incorporating restricted cubic splines (RCS) function, were employed to examine both linear and non-linear associations between FMR and cancer risk in men and women. …”
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Tumor associated neutrophils promote prostate cancer progression by mediating neutrophil trap secretion through PSMA1- NF-κB-HIF-1α signaling axis by Qian Dai, Qian Dai, Hua Wang, Hua Wang, Fang Li, Fang Li, Runchun Huang, Runchun Huang, Chenjun Jiang, Chenjun Jiang, Liuya Yuan, Liuya Yuan, Yayun Wang, Yayun Wang, Xun Li, Xun Li

“…Notably, the deconvolution algorithm revealed different compositions of the tumor microenvironment, with a greater proportion of neutrophils observed in the high-risk group. ③ Finally, we conducted single-cell sequencing analysis and established a prostate cancer organoid model to confirm that TANs may exacerbate the TME in PCa via neutrophil trap formation, which is mediated by the PSMA1-NF-κB-HIF-1α signaling axis. …”
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ASPECTS OF ASSESSING AESTHETIC PARAMETERS IN PATIENTS by P.Z. Ozhohan, Z.R. Ozhogan

“…To study the state of the maxillofacial system , we have created the “Map of determining the level of aesthetics” , which includes an analysis of the shape and colour of the teeth , the condition of the gums , the presence of restorations , the state of occlusal relationships and oral hygiene. 230 people aged 18-45 were examined, intraoral scanning and model scanning were used. General clinical examination methods were carried out, radiological methods were used. …”
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Chronotope of Russian Works about Robinson by T. V. Shvetsova, V. E. Shakhova

“…The relevance of the study is due to the appeal to the universal of the chronotope, which contains an exhaustive toolkit for the artistic embodiment of images of space and time; as well as the search for new methods of literary analysis of the text. It is shown that in the analyzed texts, a kind of fusion of Russianlanguage compositions with a foreigncultural text in the aspect of a chronotope is realized. …”
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Classification of transaction costs of rent business entities by S.V. Bardash, Т.S. Osadcha

“…The methodological basis of the study is the dialectical method of knowing the essence of rent relations and measures to improve them; bibliographic method for identification of transaction costs in the context of theories of ownership, institutionalism, agency relations and collaboration alliances as a theoretical basis for the implementation of rent relations; comparative analysis of the economic essence, causes and classification of transaction costs; abstract-logical method for substantiation of basic theoretical positions, formulation of conclusions; modeling method for constructing the classification of transaction costs of rent business entities. …”
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Parameter optimization for multistage horizontal well fracturing based on multi-cluster perforation for deep coal measure gas: A case study of the Jurassic Baijiahai area in the Ju... by Bo WANG, Chenghong JIN, Jiang LIU, Zhiwei WANG, Shenjian LI, Mao SHENG

“…As a result, existing fracturing experience cannot be directly applied, highlighting the investigation of fracturing parameter optimization tailored for deep CMG production.MethodsFocusing on deep CMG reservoirs in the Baijiahai area within the Junggar Basin, this study constructed a model of multistage horizontal well fracturing based on multi-cluster perforation for a composite geological structure composed of a roof, a floor, gangue, and coals. …”
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Shramahara Mahakasya, a traditional polyherbal formulation, induces anti-anxiety activity in hippocampal neurons by effectuating SOD2-mediated protection against oxidative stress by Saakshi Saini, Viney Kumar, Swati Haldar, Samrat Chauhan, Pratibha Demiwal, Souvik Ghosh, Sumeet Gupta, Debabrata Sircar, Bidhan Mahajon, Partha Roy

“…In this study, we investigated the intricate mechanisms through which SM polyherbal extract exerts neuroprotective and anxiolytic effects in cultured HT-22 cells and rodent models. Method: In this study, the chemical composition of SM was first identified using gas chromatography-mass spectrometry (GC-MS) and liquid chromatography-mass spectrometry (LC-MS). …”
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Photodynamic therapy with a novel photosensitizer inhibits DSS-induced ulcerative colitis in rats via the NF-κB signaling pathway by Yumei Rong, Yumei Rong, Yumei Rong, Yumei Rong, Yumei Rong, Minghui Zhu, Minghui Zhu, Minghui Zhu, Minghui Zhu, Nan Wang, Nan Wang, Nan Wang, Nan Wang, Feiyu Zhang, Feiyu Zhang, Feiyu Zhang, Feiyu Zhang, Tianjun Liu

“…IntroductionUlcerative colitis (UC) is an inflammatory bowel disease characterized by inflammation and ulceration of the digestive tract.MethodsPhotodynamic therapy (PDT) with a novel photosensitizer LD4 was used to treat UC rat models to explore the therapeutic effect and mechanism of LD4-PDT on UC. 16S ribosomal RNA was used to detect the composition of Gut microbiota.ResultsOur findings indicate that LD4-PDT could protect the integrity of the colonic mucosa, alleviate the inflammatory response and promote the healing of colonic mucosa. …”
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Machine learning prediction of obesity-associated gut microbiota: identifying Bifidobacterium pseudocatenulatum as a potential therapeutic target by Hao Wu, Yuan Li, Yuxuan Jiang, Xinran Li, Shenglan Wang, Changle Zhao, Changle Zhao, Ximiao Yang, Baocheng Chang, Juhong Yang, Juhong Yang, Jianjun Qiao, Jianjun Qiao

“…We assessed the anti-obesity effects of Bifidobacterium pseudocatenulatum through experimentation with Caenorhabditis elegans and C3H10T1/2 cells.ResultsOur analysis revealed a significant correlation between gut bacterial composition and body weight. The top 40 bacterial species were utilized to develop ML models, with XGBoost demonstrating the highest predictive accuracy. …”
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A BOX-YOLOv8 framework for automated hyperspectral core analysis by Hongyan Zhu, Anjie Li, Chengzhi Lin, Shuai Qin, Junhao Xie, Jackey J.K. Chai, Russell Rogers, Jun-Li Xu

“…This framework leverages a synergistic integration of deep learning models—specifically BOX-YOLOv8, SAM2, and a custom MLP—to achieve efficient, automated end-to-end processing. …”
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Finite Element and Vulnerability Analyses of a Building Failure due to Landslide in Kaithakunda, Kerala, India by Rajkumar Andrewwinner, Sembulichampalayam Sennimalai Chandrasekaran

“…The original slope before the vertical cut was modelled as the first stage. The vertical cut was modelled in the second stage to study the actual site condition before failure. …”
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Optimization of microencapsulation of green tea extract for functional beverage development by Elizaveta Kochubei, Igor Lomovskiy, Oleg Lomovsky, Jibek Baktybekova, Vyacheslav Koptev, Anastasia Andreeva, Anna Matveeva, Alexander Vorobyov, Aml A. Tantawy, Mohamed Hamdy Eid, Tamer M. El-Messery, Elena Bychkova

“…Based on the analysis of rheological properties, the optimal ratio of hydrocolloids was established as 40:60 (gum arabic:maltodextrin). Mathematical modeling was used to optimize the ingredient composition of the additive, revealing that the optimal ratio of shell material to core material was 80:20.In the development of functional beverages using the additive, various liquid food bases were tested, including neutral (water, apple juice) and tart berry beverages. …”
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Crohn’s disease therapeutic dietary intervention (CD-TDI): study protocol for a randomised controlled trial by Subrata Ghosh, Levinus A Dieleman, Christopher Ma, Ian Lewis, Herman W Barkema, Humberto Jijon, Kathy D McCoy, Georgios V Gkoutos, Maitreyi Raman, Lorian M Taylor, Jeff K Vallance, Derek M McKay, David M Mutch, Deanna Gibson, Marcus Rauch

“…Predictive models of clinical response to a CD-TDI will be investigated.Ethics and dissemination The research protocol was approved by the Conjoint Health Research Ethics Board at the University of Calgary (REB19-0402) and the Health Research Ethics Board—Biomedical Panel at the University of Alberta (Pro00090772). …”
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Prognostic impact of coronary microvascular dysfunction in patients with myocardial infarction evaluated by new angiography-derived index of microvascular resistance by Benoit Caullery, Laurent Riou, Stephanie Marliere, Estelle Vautrin, Nicolas Piliero, Olivier Ormerzzano, Helene Bouvaist, Gerald Vanzetto, Gilles Barone-Rochette

“…Background: Several methods for measuring IMR derived from angiography have been developed. …”
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Zero-Shot Remote Sensing Scene Classification Based on Automatic Knowledge Graph and Dual-Branch Semantic Correlation Supervision by Chao Wang, Jiajun Yang, Tanvir Ahmed, Yang Zhao, Tong Zhang, Bing Sun, Tao Xie, Jie Wang, Tianyu Chen

“…To address these limitations, this article proposes the “zero-shot remote sensing scene classification via automatic knowledge graph and dual-branch semantic correlation supervision (AKG-DBSS).” This method starts with the scenes and automates the construction of a knowledge graph, “scene-landscape-ground objects” (ASLG-KG), by analyzing the composition and spatial distribution of ground objects in local regions. …”
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The deficiency of chymase mast cell protease 4 exacerbates dextran sulfate sodium salt-induced colitis in mice and is associated with altered microbiota and metabolome profiles by Zhiqiang Li, Zhiqiang Li, Zhiqiang Li, Xiaoyuan Kuang, Dashuang Mo, Magnus Åbrink, Ge Shan, Jin-ping Li, Can Yang, Yuexi Wang, Tao Shen, Weiwei Yu

“…Furthermore, the Mcpt-4∆Cre colitis mice displayed a distinct shift in colonic microbiota composition, notably with significantly increased abundance of bacteria (Akkermansia and Turicibacter), associated with potentially worsened inflammation in colitis models. …”
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Magnetically Active GO-Fe₃O₄ Nanocomposite for Enhanced Rhodamine B Removal Efficiency by Alexander Souhuat, Henry Fonda Aritonang, Harry Steven Julius Koleangan

“…The adsorption followed the pseudo-second-order kinetics model with 0.00016 mg/g min adsorption rate while the adsorption isotherm followed the Langmuir model where adsorbent surfaces are spread homogeneously by forming a monolayer.…”
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Research on evaluation of basic railway safety management capability based on combination weighting – TOPSIS by Yankun Qi, Xiaoyu Li, Jinghui Liu, Hanqiu Li, Chen Yang

“…Game theory combination weighting is utilized to integrate subjective and objective weight values derived using AHP and CRITIC methods and further combined using the TOPSIS method in order to construct a comprehensive basic railway safety management capability evaluation model. …”
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Harvesting decellularized liver extracellular matrix from rodents for 3D scaffold fabrication by Meghana Kasturi, Kirthanashri S. Vasanthan

“…In this study, we report an injection-based decellularization method, without perfusion setup. This study also compares the efficiency of the proposed protocol in the two animal models viz rat and mice. …”
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Development of snow-blowing structures for protection roads from snow drifts by D. N. Sannikov, V. V. Servatinsky

“…The article discusses the use of the snow blowing method and the possibility of installing snowblowing structures on highways to protect against snow drifts. …”
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