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  1. 4141

    Experimental studies of natural material-based coatings for thermal protection of metallic surfaces by Alexander A. Genbach, David Yu. Bondartsev, Natalia A. Genbach, Ekaterina A. Genbach

    Published 2025-03-01
    “…The thermodynamic characteristics of thermal tools have been established in the model and experimentally; the granulometric composition of materials has been obtained; the hydrodynamic operating modes of the burners have been selected (fuel combustion method, jet length, jet angle). …”
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  2. 4142

    Distribution of vehicle speeds in traffic flow on multilane roads approaching major and metropolitan cities by Oksana Hulchak, Stanislav Popov, Liudmyla Nahrebelna, Alina Korchevska

    Published 2025-06-01
    “…Specifically, the investigation focused on assessing the conformity of empirical data to the normal distribution model, establishing characteristic speed ranges by vehicle type, and evaluating the influence of traffic volume and traffic flow composition on speed parameters. …”
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  3. 4143

    Research on Rotary Magnetorheological Finishing of the Inner Surface of Stainless Steel Slender Tubes by Zhaoyang Luo, Chunya Wu, Ziyuan Jin, Bing Guo, Shengdong Gao, Kailei Luo, Huiyong Liu, Mingjun Chen

    Published 2025-06-01
    “…This method does not require frequent replacement of the polishing medium during the processing, which helps to simplify the processing technology. …”
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  4. 4144

    Closed-eye intraocular pressure and eye movement monitoring via a stretchable bimodal contact lens by Xingyi Gan, Guang Yao, Cunbo Li, Yufeng Mu, Maowen Xie, Chenzheng Zhou, Peisi Li, Qiwei Dong, Ke Chen, Kangning Zhao, Min Gao, Taisong Pan, Fang Lu, Dezhong Yao, Peng Xu, Yuan Lin

    Published 2025-05-01
    “…Ex vivo and in vivo MEM monitoring, based on composition-optimized magnetic interlayer film, demonstrated exceptional accuracy (≥97.25%) with eyes open and closed, surpassing existing methods. …”
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  5. 4145

    Novel molecular mechanisms of immune evasion in hepatocellular carcinoma: NSUN2‐mediated increase of SOAT2 RNA methylation by Jinhua Jiang, Feng Liu, Dan Cui, Caixia Xu, Jiachang Chi, Tinghua Yan, Fang Guo

    Published 2025-07-01
    “…This study aimed to examine the molecular mechanisms underlying the involvement of NSUN2 in immune evasion and metabolic reprogramming of HCC. Methods Single‐cell transcriptomic sequencing was applied to examine cellular composition changes, particularly immune cell dynamics, in HCC and adjacent normal tissues. …”
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  6. 4146

    Gender and cultural aspects of brucellosis transmission and management in Nakasongola cattle corridor in Uganda. by Christine Tricia Kulabako, Stella Neema, Lesley Rose Ninsiima, Jörn Klein, Lydia Namakula Nabawanuka, James Muleme, Javier Sánchez Romano, Peter Atekyereza

    Published 2025-01-01
    “…Data were collected using face -to -face interviews with an interview guide that was structured using the Socio Ecological Model of Human Behaviour framework (SEMHB) constructs. …”
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  7. 4147

    Gut virome dysbiosis impairs antitumor immunity and reduces 5-fluorouracil treatment efficacy for colorectal cancer by Hui Huang, Hui Huang, Ying Yang, Xiaojiao Wang, Xiaojiao Wang, Biao Wen, Biao Wen, Xianglan Yang, Wei Zhong, Wei Zhong, Qiurong Wang, Qiurong Wang, Feng He, Feng He, Jun Li, Jun Li

    Published 2024-12-01
    “…In this study, we investigated the impact of antiviral (AV) drug-induced gut virome dysbiosis on the efficacy of 5-FU in CRC treatment.MethodsUsing a subcutaneous CRC mouse model, we assessed tumor growth and immune responses following AV treatment, fecal microbiota transplantation (FMT), and 5-FU administration.ResultsAV therapy reduced the abundance of gut DNA and RNA viruses, leading to accelerated tumor growth, shortened survival, and diminished chemotherapy efficacy. …”
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  8. 4148

    Houttuynia cordata-Derived Exosome-Like Nanoparticles Mitigate Colitis in Mice via Inhibition of the NLRP3 Signaling Pathway and Modulation of the Gut Microbiota by Li JH, Xu J, Huang C, Hu JX, Xu HM, Guo X, Zhang Y, Xu JK, Peng Y, Zhang Y, Zhu MZ, Zhou YL, Nie YQ

    Published 2024-12-01
    “…A dextran sulfate sodium (DSS)-induced colitis mouse model was utilized to assess the therapeutic potential of HELNs in UC. …”
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  9. 4149

    Comparison of the Blood–Brain Barrier Penetration Ability and Anti-Neuroinflammatory Activity of Chromones in Two Types of Agarwood by Mengyuan Yang, Yanan Yuan, Jingfan Wei, Yifei Pei, Yuanfei Niu, Yifan Zhao, Xiangying Kong, Zhijie Zhang

    Published 2025-03-01
    “…Subsequently, an in vitro neuroinflammatory model was established via lipopolysaccharide (LPS)-stimulated BV-2 cells to evaluate the anti-neuroinflammatory activity of differential chromones. …”
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  10. 4150

    Analysis of the spatiotemporal evolution and driving factors of land use change in Jinan springs area of the Northern Karst region, China from 1986 to 2022 by Shenting Gang, Xiaoyun Kong, Tao Jia, Minghui Lv, Lixia Li

    Published 2025-04-01
    “…To explore the land-use change characteristics and their driving mechanisms, six periods of Landsat series land-use data were collected for the years 1986, 1995, 2000, 2009, 2016 and 2022. A Random Forest model was employed for classifying the remote sensing data, while the land use dynamic and land use transfer matrix were used to analyse the scale, composition, morphology, pattern and spatial and temporal characteristics of land use changes from 1986 to 2022. …”
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  11. 4151

    Ginsenoside Reshapes Intestinal Microecology to Alleviate Microgravity Stress by Wang Y, Chen T, Shi Z, Dong L, Li M, Peng B, Li Q, Pan R, Xiao S, Yang Q, Jiang N, Liu X, Hu Q, Chen Y

    Published 2025-02-01
    “…This study focused on the regulation of GTSs in intestinal homeostasis imbalance caused by microgravity.Methods: A hindlimb suspension (HLS) rat model was established to evaluate the intestinal protective effects of GTSs. …”
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  12. 4152

    Adjuvanticity of Tannic Acid-Modified Nanoparticles Improves Effectiveness of the Antiviral Response by Janicka M, Chodkowski M, Osinska A, Bylinska K, Obuch-Woszczatyńska O, Patrycy M, Chodaczek G, Ranoszek-Soliwoda K, Tomaszewska E, Celichowski G, Grobelny J, Cymerys J, Krzyżowska M

    Published 2025-04-01
    “…HSV-1 also invades the nervous system where it establishes a lifelong latency-making infection poorly treatable We previously showed that both tannic acid-modified silver and gold nanoparticles (TA-Ag/AuNPs) inhibit HSV-1 infection in vitro.Methods: We used an in vitro and in vivo model of HSV-1 infection to study how metal type, size and tannic acid modification of nanoparticles can influence development of the early innate response and the mounting of specific anti-HSV-1 response upon treatment of the nasal mucosa.Results: We found that tannic acid is necessary for binding with HSV-1, with smaller sizes independent of the NPs composition, whereas for larger NPs, only TA-AgNPs can inhibit HSV-1 infection. …”
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  13. 4153

    Small intestinal bacterial overgrowth and metabolic dysfunction-associated steatotic liver disease by Ziteng Wang, Ziteng Wang, Wentao Tan, Jiali Huang, Qian Li, Jing Wang, Hui Su, Chunmei Guo, Hong Liu

    Published 2024-12-01
    “…For heterogeneity >50%, a random effects model was used. There was a clear association between SIBO and MASLD (OR = 3.09; 95% CI 2.09–4.59, I2 = 66%, p < 0.0001). …”
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  14. 4154

    Progression to fibrosis and hepatocellular carcinoma in DEN CCl4 liver mice, is associated with macrophage and striking regulatory T cells infiltration by Ananya Ajith, Jonathan Evraerts, Caroline Bouzin, Davide Brusa, Makram Merimi, Mehdi Najar, Mehdi Najar, Françoise Smets, Etienne Sokal, Mustapha Najimi

    Published 2025-07-01
    “…This study investigates immune dysregulation that occurs during the progression of CLD to HCC by delineating changes in immune cell composition and distribution within the liver microenvironment.MethodsMice were injected with Diethylnitrosamine (DEN) at 4 weeks of age, followed by continuous tri-weekly injections of carbon tetrachloride (CCl4) for 6 and 21 weeks to induce liver fibrosis and HCC. …”
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  15. 4155

    Gut microbiota metabolite acetate mediates free fatty acid receptor 2 expression to alleviate atopic dermatitis by Siqi Ye, Siqi Ye, Jingwen Wang, Jingwen Wang, Feng Luo, Feng Luo, Jinjing Jia, Jinjing Jia, Xiumei Mo, Xiumei Mo, Dacan Chen, Dacan Chen

    Published 2025-08-01
    “…However, their potential associations and mechanisms remain unclear.MethodsThis study used antibiotics to construct a mouse model to analyze the performance of AD mice after gut microbiota destruction. 16S rRNA amplicon sequencing combined with HM700 high-throughput metabolomics was used to characterize differential microbial components and key metabolites in fecal specimens of AD murine models. …”
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  16. 4156
  17. 4157

    Characteristics of the gut virome in patients with premalignant colorectal adenoma by Pan Zhang, Xiaofeng Tuo, Jiong Jiang, Yue Zhang, Juhui Zhao, Chengzhao Deng, Gang Zhao, Yan Cheng, Lingqin Song, Yan Yang, Ruochun Guo, Huan Zhang, Hongli Zhao, Shiyang Ma, Lu Li, Haitao Shi

    Published 2025-05-01
    “…., bacteriome, mycobiome, and virome) characteristics of colorectal cancer have been extensively studied, yet there is still an insufficient description of the microbiota features in its early-stage, colorectal adenoma, particularly in the gut virome aspect. Methods Based on the Metagenomic Gut Virus catalogue (MGV) containing 54,118 non-redundant gut viral genomes, this study characterized the virome composition and diversity using publicly available metagenomic sequencing data from 419 individuals with premalignant colorectal adenoma and 552 healthy controls. …”
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  18. 4158
  19. 4159

    Sex-Dependent Effects of Body Fat on Cardiac Function and Outcomes in Community-Dwelling Older Adults by Haowen Jiang, MBBS, Jie Jun Wong, MBBS, Glades H.M. Tan, BEng, Louis L.Y. Teo, MBBS, See Hooi Ewe, MBBS, PhD, Ru-San Tan, MBBS, Fei Gao, PhD, Angela S. Koh, MBBS, MPH, PhD

    Published 2025-09-01
    “…Objectives: The authors aimed to study the effects of sex on body fat composition and aging-related diastolic function, as well as their longitudinal changes. …”
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  20. 4160

    Fecal profiling reveals a common microbial signature for pancreatic cancer in Finnish and Iranian cohorts by Heidelinde Sammallahti, Sama Rezasoltani, Satu Pekkala, Arto Kokkola, Hamid Asadzadeh Agdaei, Mehdi Azizmohammad Looha, Reza Ghanbari, Farhad Zamani, Amir Sadeghi, Virinder Kaur Sarhadi, Marja Tiirola, Pauli Puolakkainen, Sakari Knuutila

    Published 2025-04-01
    “…The inadequacy of current screening methods has prompted investigations into stool-based assays and microbial classifiers as potential early detection markers. …”
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