Liver-Targeting Nanoparticles GA-MSe@AR Treat NAFLD Through Dual Lipid-Lowering and Antioxidant Efficacy by Lei S, Wu Q, Zhang B, Lu M, Xia Y, Li N

“…In both in vitro and in vivo NAFLD models, GA-MSe@AR demonstrated more pronounced lipid-lowering and antioxidant properties than AR and GA-MSe. …”
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Bifidobacterium animalis BD400 protects from collagen-induced arthritis through histidine metabolism by Yang Yang, Yang Yang, Qing Hong, Qing Hong, Xuehong Zhang, Zhenmin Liu, Zhenmin Liu

“…This research aims to restore intestinal microbiota to a healthy state through the oral administration of Bifidobacterium in the early stages with the goal of delaying the onset and progression of RA.MethodsCollagen-induced arthritis (CIA) rat model was constructed to assess the development of RA using arthritis clinical scores, paw thickness, pathological analysis of knee joint. …”
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Ameliorative Effect of Lacticaseibacillus paracasei Combined with Aerobic Exercise on Obesity in Mice by ZHAO Hanyi, CAO Sijia, QI Jianing, BIAN Yanqing, ZHANG Jiaqi, GAO Yuqi, FENG Zhaoyang, SUN Wenjing, XUE Yuling, WANG Yanhong, PENG Liping

“…Objective: To investigate the effect of Lacticaseibacillus paracasei N1115 combined with aerobic exercise on improving glucose and lipid metabolism, inflammatory response, learning and memory capacity, intestinal morphology and intestinal flora diversity in obese mice. Methods: C57BL/6 mice were used to establish an obese mouse model by feeding them a high-fat diet. …”
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Host-specific effects of Eubacterium species on Rg3-mediated modulation of osteosarcopenia in a genetically diverse mouse population by Soyeon Hong, Bao Ngoc Nguyen, Huitae Min, Hye-Young Youn, Sowoon Choi, Emmanuel Hitayezu, Kwang-Hyun Cha, Young Tae Park, Choong-Gu Lee, GyHye Yoo, Myungsuk Kim

“…This study investigated the interplay between host genetics, gut microbiota, and musculoskeletal health in a mouse model of osteosarcopenia, exploring the therapeutic potential of gut microbiota modulation. …”
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New bitongling regulates gut microbiota to predict angiogenesis in rheumatoid arthritis via the gut-joint axis: a deep neural network approach by Yin Guan, Xiaoqian Zhao, Yun Lu, Yue Zhang, Yan Lu, Yue Wang

“…Recent research indicates that gut microbiota might be pivotal in RA development through the “gut-joint axis,” presenting novel therapeutic possibilities.PurposeThis study seeks to explore the therapeutic potential of the traditional Chinese medicine (TCM) compound new bitongling (NBTL) for RA, with an emphasis on its capacity to regulate gut microbiota and suppress angiogenesis via the vascular endothelial growth factor (VEGF) signaling pathway.MethodsWe utilized a collagen-induced arthritis (CIA) rat model to assess the impact of NBTL. …”
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Combination ATR-FTIR with Multiple Classification Algorithms for Authentication of the Four Medicinal Plants from <i>Curcuma</i> L. in Rhizomes and Tuberous Roots by Qiuyi Wen, Wenlong Wei, Yun Li, Dan Chen, Jianqing Zhang, Zhenwei Li, De-an Guo

“…Then, t-distributed stochastic neighbor embedding (t-SNE) was applied to visualize the results, and seven kinds of classification models were constructed. The results showed that support vector machine (SVM) modeling was superior to other models and the accuracy of validation and prediction was preferable, with a modeling time of 127.76 s. …”
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Exposure to diverse airborne bacterial communities following Klebsiella pneumoniae infection elicits distinct host response mechanisms in mice by Chenchen Song, Li Zhou, Lianlian Zhao, Zhi Guo, Lifang Zhang, Hu Yang, Yuhan Lei, Yunlin Han, Yanfeng Xu, Zhiguang Xiang, Baicun Li, Jianguo Guo

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Therapeutic effects of raw rhubarb on gastrointestinal complications in ischemic stroke: An integrated analysis of gut microbiota, metabolomics, and network pharmacology by Zhanhao Ye, Dongmin Cao, Wenxing Ao, Ting Li, Minghua Xian, Shumei Wang

“…The rats were divided into six groups: sham, model, nimodipine-treated, and three different dose groups for RR. …”
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Taltirelin induces TH expression by regulating TRHR and RARα in medium spiny neurons by Kedong Zhu, Lanxia Meng, Jiaying Luo, Tingting Wen, Liang Dan, Zhihao Wang, Xuebing Cao, Zhaohui Zhang, Guiqin Chen

“…In this study, a variety of in vivo and in vitro methods, including transcriptomic analysis, were employed to elucidate the effects of Taltirelin on cellular composition and signaling pathways in the striatum of hemi-PD rats. …”
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Core thermal profiling application in additional geology structure appraisal of Permian-Carboniferous deposits at Usinsk oil field by E. Yu. Popov, E. M. Chekhonin, S. S. Safonov, S. O. Ursegov, I. P. Gurbatova

“…The data are necessary for the hydrodynamic modeling of the heat and mass transfer processes in reservoirs at the thermal methods of the enhanced oil recovery. …”
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Cabin dynamics simulation of “Rope Metro” transport system by I. A. Lagerev, A. V. Lagerev, A. V. Panfilov, E. V. Marchenko

“…This model should be integrated into the composite mathematical model of the transport system using part of its output capacity. …”
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A proof-of-concept study of personalized dosimetry for targeted radioligand therapy using pre-treatment diagnostic dynamic PET/CT and Monte Carlo simulation by Thanh Tai Duong, Danny De Sarno, Hatim Fakir, Glenn Bauman, Martin Martinov, Rowan M. Thomson, Ting-Yim Lee, Ting-Yim Lee, Ting-Yim Lee

“…Here we establish a proof-of-concept framework using pre-treatment PET/CT to predict TRT doses via graphical analysis and Monte Carlo modeling, eliminating the need for serial imaging. …”
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Estimation of the water content of needles under stress by Erannis jacobsoni Djak. via Sentinel-2 satellite remote sensing by Jiaze Guo, Xiaojun Huang, Xiaojun Huang, Xiaojun Huang, Debao Zhou, Junsheng Zhang, Gang Bao, Gang Bao, Siqin Tong, Siqin Tong, Yuhai Bao, Yuhai Bao, Dashzebeg Ganbat, Dorjsuren Altanchimeg, Davaadorj Enkhnasan, Mungunkhuyag Ariunaa

“…Its damage predominantly affects pine species, resulting in significant changes to the biochemical composition of needle leaves. Needle leaf water content exhibits a clear response to these changes and is highly sensitive in reflecting the degree of tree damage.MethodsIn this work, we combine vegetation indices with machine learning algorithms to estimate the water content of needles at a large scale. …”
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Dynamic monitoring of Staphylococcus epidermidis biofilm formation using a microfluidic approach by Sahra Fonseca, Jonathan Robidoux, Marie-Pierre Cayer, Jolianne Matte, Steve J. Charette, Danny Brouard

“…This study evaluated the performance of different methods for assessing biofilm formation under various growth conditions, using Staphylococcus epidermidis as a model bacterium. …”
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Assessment of serological tests for antibodies to different antigens of the SARS-CoV-2 virus: comparison of six immunoassays by V. V. Belyakova, O. A. Maiorova, N, V. Ivanova, I. E. Stepanova, M. A. Smerdova, A. P. Obryadina, A. P. Toptygina

“…ROC analysis revealed a high diagnostic value of all tested kits (AUC from 0.908 to 0.998), which indicates a high quality of the separation model of positive and negative samples (p &lt; 0.001). …”
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Nighttime Pistachio Consumption Alters Stool Microbiota Diversity and Taxa Abundance Compared with Education to Consume 1–2 Carbohydrate Exchanges (15–30 grams) over 12 Weeks in Ad... by Terrence M Riley, Justin Wright, Regina Lamendella, Jordan E Bisanz, Jeremy Chen See, Khushi Kanani, Penny M Kris-Etherton, Kristina S Petersen

“…Taxonomic diversity was tested with linear mixed models (LMMs) and permutational analysis of variance of Bray–Curtis and weighted Unifrac dissimilarity indices. …”
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Methylation-based biological age and cardiotoxicity risk in breast cancer patients treated with trastuzumab by Jamila Mammadova, Alicia Richards, Adriana Gonzalez-Torriente, Evan R. Adler, Rachel J. Cruz, Stefanie Palfi, Dae Hyun Lee, Christine Sam, Mohammed Al-Jumayli, Anders Berglund, Jong Y Park, Mohammed Alomar, Jacob K. Kresovich

“…Methods Among a retrospective cohort of HER2-positive breast cancer patients treated with trastuzumab at Moffitt Cancer Center, we profiled blood DNA methylation and genetic profiles. …”
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Management and Operation Transformation of Urban Park Green Spaces from the Perspectives of Public Goods Provision and Fiscal Sustainability by Peiyi JIA

“…The research also raises the perspective that the sustainable financial model for park green spaces is important. Considering that the current project-based investment model for public infrastructure often creates conflicts between short-term incentives and sustainability goals, the life-cycle financial assessment framework must be taken as the foundation of the financial model. …”
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High level of soluble tumor necrosis factor receptors is associated with lower residual diuresis volume in patients on hemodialysis: An exploratory study. by Gabriele Teixeira Gonçalves, Luciana Martins de Mello Santos, Pedro Henrique Scheidt Figueiredo, Jaqueline de Paula Chaves Freitas, Jousielle Márcia Santos, Joyce Noelly Vitor Santos, Fidelis Antônio da Silva Junior, Frederico Lopes Alves, Vanessa Gomes Brandão, Emílio Henrique Barroso Maciel, Maria Cecília S M Prates, Borja Sañudo, Redha Taiar, Mario Bernardo-Filho, Danúbia da Cunha de Sá-Caputo, Vanessa Pereira Lima, Henrique Silveira, Victor Lacerda Gripp, Vanessa Amaral Mendonça, Ana Cristina Rodrigues Lacerda

“…Data analyses were conducted using both single and multiple regression models, adjusted for the confounding parameters.<h4>Results</h4>Of the total sixty participants, 27 (45%) were classified as anuric, and 33 (55%) as non-anuric. …”
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Tephrostratigraphy of Jurassic-Cretaceous boundary beds of Western Siberia by Panchenko Ivan Vladimirovich, Rogov Mikhail, Sobolev Ivan Dmitrievich, Latyshev Anton, Zakharov Victor

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