High-Risk Consult Multidisciplinary Team in a Tertiary Maternity Unit: Changing Prevalence of Cases by Ng YHG, Wright A, Ng YYV, Kavalloor NV, Tan LK, Quek BH, Tan KH

“…The High-Risk Consult (HRC) brings together a multidisciplinary team of specialists, including maternal–fetal medicine specialists, neonatologists, anaesthesiologists, and relevant subspecialities to provide comprehensive, individualized care for these complex pregnancies. While this model of care delivery is increasingly adopted worldwide, data on the prevalence and patterns within such multidisciplinary services remains limited.Objective: To describe the types of high-risk antenatal cases managed by an HRC and compare the prevalence of these conditions across two distinct time periods.Methods: This retrospective observational study analyzed all cases discussed at the HRC of a single tertiary center, KK Women’s and Children’s Hospital (KKH), in Singapore. …”
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Investigating male factors and their relationships with reproductive health outcomes: a case-control study protocol for Towards Optimal Fertility, Fathering, and Fatherhood studY (... by Fabian Yap, See Ling Loy, Yin Bun Cheung, Jerry Kok Yen Chan, Keith Godfrey, Chee Wai Ku, Jun Wei Pek, Melissa D/O Tharmalingam Durgahshree, Melinda Chan, Yie Hou Lee

“…Predictive male factors will be identified using the least absolute shrinkage and selection operator method, accounting for female factors. We will construct a logistic regression model incorporating both male and female factors to derive a fertility index, which will be evaluated using cross-validation on subsets of the study population. …”
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Innovative Resource-Saving Equipment for Safflower Processing to Improve Oil Quality by Maigul Mursalykova, Gulnara Kokayeva, Mukhtarbek Kakimov, Bożena Gajdzik, Radosław Wolniak, Damian Dzienniak, Michał Bembenek

“…A comparative analysis of the physicochemical and fatty acid profiles of safflower oil produced using traditional and combined grinding-pressing methods confirmed the superiority of the new approach. …”
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Non-Invasive Multiclass Diabetes Classification Using Breath Biomarkers and Machine Learning with Explainable AI by Alberto Gudiño-Ochoa, Julio Alberto García-Rodríguez, Raquel Ochoa-Ornelas, Eduardo Ruiz-Velazquez, Sofia Uribe-Toscano, Jorge Ivan Cuevas-Chávez, Daniel Alejandro Sánchez-Arias

“…This study presents a breath-based multiclass diabetes classification system leveraging only three gas sensors (CO, alcohol, and acetone) to analyze exhaled breath composition. <b>Methods</b>: Breath samples were collected from 58 participants (22 healthy, 7 prediabetic, and 29 diabetic), with blood glucose levels serving as the reference metric. …”
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Biostimulant-Based Molecular Priming Improves Crop Quality and Enhances Yield of Raspberry and Strawberry Fruits by Petar Kazakov, Saleh Alseekh, Valentina Ivanova, Tsanko Gechev

“…Background/Objectives: The biostimulant SuperFifty, produced from the brown algae <i>Ascophyllum nodosum</i>, can improve crop quality and yield and mitigate stress tolerance in model and crop plants such as <i>Arabidopsis thaliana</i>, pepper, and tomato. …”
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Correction of Batch Effect in Gut Microbiota Profiling of ASD Cohorts from Different Geographical Origins by Matteo Scanu, Federica Del Chierico, Riccardo Marsiglia, Francesca Toto, Silvia Guerrera, Giovanni Valeri, Stefano Vicari, Lorenza Putignani

“…The ASD GM markers were identified by the random forest (RF) model. Results: We observed a different GM profile in patients with ASD compared with NC subjects. …”
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A randomized controlled trial utilizing an interactive accelerometer linked to a smartphone application for enhancing physical activity and health among military employees by Emilia Pietiläinen, Emilia Pietiläinen, Heikki Kyröläinen, Heikki Kyröläinen, Kai Parkkola, Kai Parkkola, Tiina Luukkaala, Tiina Luukkaala, Tommi Vasankari, Tommi Vasankari

“…The effect of the intervention on primary and secondary outcomes was analyzed using unadjusted generalised linear mixed model, accounting for a group-by-time interaction effect in all models.ResultsThere was no statistically significant group-by-time interaction regarding the measured parameters. …”
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Perivascular Lymphocyte Clusters Induced by Gastric Subserous Layer Vaccination Mediate Optimal Immunity against Helicobacter through Facilitating Immune Cell Infiltration and Loca... by Chupeng Hu, Wei Liu, Ningyin Xu, An Huang, Zhiqin Zeng, Shuanghui Luo, Zhenxing Zhang, Menghui Fan, Feng Ye, Tao Xi, Yingying Xing

“…The composition of the gastric lymphocyte clusters was analyzed by immunofluorescence staining. …”
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Actions of annatto-extracted tocotrienol supplementation on obese postmenopausal women: study protocol for a double-blinded, placebo-controlled, randomised trial by Rui Wang, JaeHoon Lee, Amir Aryaie, Grant Tinsley, Bruce A Watkins, Lane Moore, Adel Alhaj-Saleh, Kartik Shankar, Sarah R Wood, Chwan-Li Shen

“…Cellular studies and high-fat-diet-induced obese mouse model mimicking obesity show the antiobesity effect of annatto-extracted tocotrienols (TT) with antioxidant capability. …”
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Modulating ultrasound-assisted extraction of polysaccharide-protein complexes from β-glucan-rich medicinal mushrooms for enhanced antioxidant activity by Emily Wan Ting Tam, Yi Ching Cheung, Wesley Chin Ho Lung, Ching Ching Hui, William W.Y. Lam, Stella Siu Mui Ng, Franklin Wang Ngai Chow

“…The growing nutraceutical interest in polysaccharide-protein complexes (PSPs) from β-glucan-rich medicinal mushrooms necessitates efficient extraction methods. This study examined the impact of various ultrasound-assisted extraction (UAE) parameters, including ultrasound power, temperature, mushroom particle size, and solid-to-liquid ratio, on the composition and antioxidant activities of PSPs extracts from Lentinula edodes (L. edodes) and Grifola frondosa (G. frondosa). …”
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Simulation and optimization of heat transfer in underground in-situ shale upgrading by LI Yuan, ZHONG Anhai, QIAN Qin, YU Denglang, ZHANG Yuzhe, ZHONG Yanlei, WANG Dan

“…A three-dimensional fracture-network heat transfer model was established. Combined with the finite element fluid simulation technology， the heat transfer law of the fracture-network was systematically simulated and analyzed， and the influence law of fracturing， gas injection volume， gas injection temperature， rock layer heating methods， and insulation on the heating effect of in-situ upgrading was explored. …”
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Reduced synaptic tagging by complement protein C3 is associated with elevated extracellular matrix in the middle-aged cerebellum of mice by Henning Peter Düsedau, Carla Cangalaya, Stoyan Stoyanov, Alexander Dityatev, Alexander Dityatev, Alexander Dityatev, Ildiko Rita Dunay, Ildiko Rita Dunay, Ildiko Rita Dunay, Ildiko Rita Dunay, Ildiko Rita Dunay

“…While the aging process affects all brain compartments at different velocities and one of the particularly affected regions is the cerebellum (CB), the underlying effects remain elusive.MethodsIn the present study, we harnessed a murine model of natural aging in males combined with orthogonal experimental approaches comprising of cytokine gene expression analysis, flow cytometry, immunohistochemistry, and flow synaptometry.ResultsWe report age-dependent morphological and phenotypic changes in microglia that are distinct in the cortex (CTX) and CB. …”
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Mobile-Based Platform With a Low-Calorie Dietary Intervention Involving Prepackaged Food for Weight Loss for People With Overweight and Obesity in China: Half-Year Follow-Up Result... by Xi Wang, Suyuan Wang, Lingyu Zhong, Chenghui Zhang, Yanhong Guo, Mingxia Li, Li Zhao, Shuming Ji, Junjie Pan, Yunhong Wu

“…Dual-energy x-ray absorptiometry and quantitative computed tomography were used to assess body fat. A multilevel model for repeated measurements was used to compare differences between the 2 groups. …”
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Linking Creatinine‐to‐Body Weight Ratio With Diabetes Incidence: A Multiethnic Malaysian Cohort Study by Noraidatulakma Abdullah, Ying‐Xian Goh, Aisyatul Najihah Khuzaimi, Azwa Shawani Kamalul Arifin, Nurul Ain Mhd Yusuf, Nazihah Abd Jalal, Norliza Ismail, Nurul Faeizah Husin, Mohd Arman Kamaruddin, Rahman Jamal

“…The Cox proportional hazards model evaluated the effect of Cre/BW ratio on developing incident diabetes. …”
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Time Course of Changes in Extravascular Water of the Lung After Pneumonectomy According to the Data of Transpulmonal Thermodilution by V. V. Kuzkov, Ye. V. Suborov, V. N. Kuklin, M. Sobkhez, M. Yu. Kirov, L. Ya. Bjertnes

“…Objective: to study the accuracy of pulmonary extravascular water (PEVW) measurement by thermochromodilution (TCD) and isolated thermodilution (ITD) on a model of pneumonectomy and subsequent ventilator-induced lung lesion (VILL) in sheep.Materials and methods: the study was conducted at the Research Laboratory of University of Tromse. …”
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Lipid accumulation inhibition strategies alleviate Fusobacterium nucleatum-infected colorectal cancer by Zhongkun Zhou, Yuqing Niu, Yunhao Ma, Dekui Zhang, Yiqing Wang, Rui Ji, Jianfang Zhao, Chi Ma, Hongmei Zhu, Yingqian Liu, Lixue Tu, Juan Lu, Baizhuo Zhang, Hua Zhang, Xin Ma, Peng Chen

“…Furthermore, the effects of Bifidobacterium animalis (B. animalis) on F. nucleatum and CRC were assessed in vitro and in vivo. Using a mouse CRC model, the function of bile salt hydrolase (BSH) in B. animalis was verified through heterologous expression in Escherichia coli (E. coli). …”
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Artificial intelligence–based diabetes risk prediction from longitudinal DXA bone measurements by Sulaiman Khan, Zubair Shah

“…To handle class imbalance, we augmented our data using Synthetic Minority Over-sampling Technique (SMOTE) and SMOTEENN (SMOTE with Edited Nearest Neighbors), and to further investigated the association between bones data features and diabetes status, we employed ANOVA analytical method. For diabetes onset prediction, we employed both conventional and deep learning (DL) models to predict risk factors associated with diabetes in Qatari adults. …”
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Activated Biocarbons Based on <i>Salvia officinalis</i> L. Processing Residue as Adsorbents of Pollutants from Drinking Water by Joanna Koczenasz, Piotr Nowicki, Karina Tokarska, Małgorzata Wiśniewska

“…Sage stems were chemically activated with two activating agents of different chemical natures—H₃PO₄ and K₂CO₃—and subjected to two thermal treatment methods: conventional and microwave heating. The effect of the activating agent type and heating method on the basic physicochemical properties of the resulting activated biocarbons was investigated. …”
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Atmospheric Cold Plasma Technology Enabling Scalable Surface‐Independent Protein Immobilization for Biosensing Applications by Lieze Dankers, Bernard Nisol, Derick Yongabi, Tom Van der Donck, Jesús Gándara Loe, Patrick Wagner, Jin Won Seo, Rob Ameloot, Karen Leirs, Jeroen Lammertyn

“…Enzyme‐linked immunosorbent assay (ELISA)‐based model bioassays demonstrate protein‐independent functionalization and linker‐layer stability of at least one month (stored in air). …”
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Spectrum of γ-Secretase dysfunction as a unifying predictor of ADAD age at onset across PSEN1, PSEN2 and APP causal genes by Sara Gutiérrez Fernández, Cristina Gan Oria, Dieter Petit, Wim Annaert, John M. Ringman, Nick C. Fox, Natalie S. Ryan, Lucía Chávez-Gutiérrez

“…Understanding this clinical variability is crucial for understanding disease mechanisms, developing predictive models and tailored interventions in ADAD, with potential implications for sporadic AD. …”
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