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3761
Self-Nanoemulsifying Drug Delivery System of Morin: A New Approach for Combating Acute Alcohol Intoxication
Published 2024-10-01“…In this study, our aim was to develop a self-nanoemulsifying drug delivery system (SNEDDS) to enhance MOR’s solubility and bioavailability, evaluate its anti-AAI effects, and investigate the underlying mechanism.Methods: The composition of MOR-loaded self-nanoemulsifying drug delivery system (MOR-SNEDDS) was determined by constructing pseudo-ternary phase diagrams, and its formulation proportion was optimized using the Box-Behnken design. …”
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3762
Mesalazine: a novel therapeutic agent for periodontitis via regulation of periodontal microbiota and inhibiting Porphyromonas gingivalis
Published 2025-01-01“…The data also suggested that mesalazine could disrupt the integrity of the P. gingivalis cell membrane and inhibit the expression of virulence factors. An animal model of periodontitis in rats was successfully constructed in vivo. …”
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3763
Approaches to discern if microbiome associations reflect causation in metabolic and immune disorders
Published 2022-12-01“…Furthermore, we addressed the impact of the gut morphology, physiology as well as diet on the microbiota composition in various models and resulting species specificities. …”
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3764
Synergistic treatment of sodium propionate and Sishen Pill for diarrhea mice with kidney-yang deficiency syndrome
Published 2025-06-01“…ObjectiveThis study aimed to investigate the therapeutic effects of sodium propionate in combination with Sishen Pill in the treatment of diarrhea with kidney-yang deficiency syndrome in mice, with a focus on its influence on intestinal microbiota, enzyme activity, and associated therapeutic outcomes.MethodsA model of diarrhea with kidney-yang deficiency syndrome was established via adenine combined with Folium sennae administration. …”
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3765
Diagnostic potential of salivary microbiota in persistent pulmonary nodules: identifying biomarkers and functional pathways using 16S rRNA sequencing and machine learning
Published 2024-11-01“…Results The salivary microbial composition in pPNs group showed significantly lower α- and β-diversity compared to healthy controls. …”
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3766
The dietary inflammation index and body mass index mediate the association between the dietary index for gut microbiota and sarcopenia in older women: evidence from NHANES 2011–201...
Published 2025-08-01“…BackgroundThe dietary index of gut microbiota (DI-GM) was developed to assess dietary quality by reflecting the diversity of the gut microbiota composition. This study examined the relationship between DI-GM and sarcopenia risk and evaluated the potential moderating effects of diet-related factors on sarcopenia risk in adult individuals.MethodsThis cross-sectional study included 8,872 adults from the National Health and Nutrition Examination Survey (NHANES) database between 2011 and 2018. …”
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3767
Association between endometriosis and gut microbiota: systematic review and meta-analysis
Published 2025-05-01“…Future research should focus on standardizing reporting methods to facilitate deeper quantitative analyses.Systematic Review RegistrationPROSPERO (registration number RD42024611701).…”
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3768
Areas of energy advantage for flowsheets of separation modes for mixtures containing components with similar volatilities
Published 2020-07-01“…Sharp distillation is not suitable for the separation of a mixture containing a pair of components exhibiting relative unity volatility with medium boiling points.Methods. The mathematical modeling in the Aspen Plus V.10.0 software package was chosen as the research method. …”
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3769
Estimating Carbon Biomass Using DNA: Phytoplankton as a Case Study
Published 2025-03-01“…DNA analysis has the potential to profile species composition and estimate species-specific carbon biomass simultaneously. …”
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3770
On possible petrol ignition on М<sub>1</sub>, М<sub>1</sub>G car catalyst converters surface
Published 2023-11-01“…An elemental composition of a film formed on a hot steel surface upon contact with petrol has been determined with the use of a scanning electron microscopeResults. …”
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3771
APOE ε4 and exercise interact in a sex‐specific manner to modulate dementia risk factors
Published 2022-01-01“…Longitudinal and cross‐sectional phenotyping were performed on the periphery and the brain, assessing markers of risk for dementia such as weight, body composition, circulating cholesterol composition, murine daily activities, energy expenditure, and cortical and hippocampal transcriptional profiling. …”
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3772
Biosorption of Chromium(III) and Copper(II) Ions onto Marine Alga sp. in a Fixed-bed Column
Published 2010-06-01“…The partial differential equations for the system were solved numerically by the finite volume method. The proposed mathematical model for the biosorption process provided a satisfactory description of the dynamics of metal ion removal in the column relative to the experimental data obtained. …”
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3773
Proglacial lake sediments – a basis for uninterrupted chronicles of the Holocene glacier variations
Published 2015-03-01“…The article covers the origin of paleolimnological method in glaciology, concerns the theoretical background of the approach, and focuses on the principal methods of analysis of the lake sediments and creating the sedimentary age-depth models. …”
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3774
Enhancing photovoltaic efficiency in Half-Tandem MAPbI3/ MASnI3 Perovskite solar cells with triple core-shell plasmonic nanoparticles
Published 2025-01-01“…Consequently, this research has conducted a two-dimensional (2D) perovskite solar cells (PSCs) simulation to develop an accurate model. The approach utilized in this study is based on the finite element method (FEM). …”
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3775
Criteria for predicting the initiation of rolling contact fatigue damage in the railway wheels and rails
Published 2019-07-01“…The methods of modeling allow predict the possibility of initiation of the fatigue cracks during operation with the sufficient accuracy in the short time. …”
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3776
Algorithmization of the problem of videoscopic evaluation of the steel ropes state
Published 2023-03-01“…The paper presents the results of preliminary testing of the developed algorithms and programs, the composition and methods for determining the main indicators for evaluating their effectiveness are proposed.…”
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3777
Focusing on scRNA-seq-Derived T Cell-Associated Genes to Identify Prognostic Signature and Immune Microenvironment Status in Low-Grade Glioma
Published 2023-01-01“…Subsequently, according to the T cell marker genes, we screened six genes for constructing the model, namely, RTN1, HERPUD1, MX1, SEC61G, HOPX, and CHI3L1. …”
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3778
Advancing Real-World Evidence Through a Federated Health Data Network (EHDEN): Descriptive Study
Published 2025-08-01“…ObjectiveThis study aims to describe the composition and characteristics of the databases harmonized within EHDEN as of September 2024. …”
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3779
The Problem of Mycotoxins and Approaches to Its Solution
Published 2025-02-01“…The main investigated methods of physical and chemical effects on mycotoxins in media of various chemical composition are noted. …”
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3780
Optimization of the Predicting of the Influenza Vaccine Strains
Published 2019-03-01“…WHO recommends the composition of the vaccine strain for each influenza season. …”
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