Short‐chain fatty acids enhance muscle mass and function through the activation of mTOR signalling pathways in sarcopenic mice by Chaoran Liu, Pui Yan Wong, Qianjin Wang, Hei Yuet Wong, Tao Huang, Can Cui, Ning Zhang, Wing Hoi Cheung, Ronald Man Yeung Wong

“…This study aimed to determine whether the use of SCFAs as a supplement can be a therapeutic strategy of sarcopenia in a pre‐clinical model. Methods Seven‐month‐old pre‐sarcopenic senescent accelerated mouse prone 8 (SAMP8) mice received daily SCFAs cocktail (acetate, butyrate, and propionate) for 3 months. …”
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Healthy Cardiovascular Status Attenuates the Detrimental Association Between Osteosarcopenic Adiposity and Alzheimer's Disease‐Related Dementia: A UK Biobank Cohort Study by Wenxu Wang, Rui Ren, Honghao Yang, Jinguo Jiang, Xingyue Ye, Chenying Wang, Xiang Ji, Wen Li, Yuhong Zhao, Yang Xia, Difei Wang

“…Background Body composition abnormalities are associated with the risk of Alzheimer's disease‐related dementia (ADRD). …”
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Skin Microbiome alterations in heroin users revealed by full-length 16S rRNA sequencing by Ruiyang Tao, Xiang Wang, Xiaoyuan Zhen, Ruocheng Xia, Kaiqin Chen, Han Zhang, Yu Deng, Suhua Zhang

“…Notably, bacterial composition differences were more pronounced in OrE and PaS than in NaS, with genus-level variations being more significant than those at the phylum level. …”
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Optimal design of high‐performance rare‐earth‐free wrought magnesium alloys using machine learning by Shaojie Li, Zaixing Dong, Jianfeng Jin, Hucheng Pan, Zongqing Hu, Rui Hou, Gaowu Qin

“…The SVR model combined with multi‐objective genetic algorithm are successfully used to optimize mechanical properties of four extruded alloys from Mg‐Ca, Mg‐Ca‐Zn, Mg‐Ca‐Mn‐Sn, and Mg‐Ca‐Al‐Zn‐Mn series alloys, respectively, and the corresponding experimental results are in good agreement with the designed ones. …”
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Gut Microbiota and Metabolic Dysfunction-Associated Steatotic Liver Disease by Emidio Scarpellini, Marialaura Scarcella, Jan F. Tack, Giuseppe Guido Maria Scarlata, Michela Zanetti, Ludovico Abenavoli

“…Thus, there is a pathophysiological link between gut dysbiosis and MASLD. <b>Aims and Methods:</b> We aimed to review the literature data on the composition of the human bacterial gut microbiota and its dysbiosis in MASLD and describe the concept of the “gut–liver axis”. …”
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Impact of Co-Spray Drying with Leucine or Trileucine on Aerosol Performance, In Vitro Dissolution, and Cellular Uptake of Colistin Powder Formulations for Inhalation by Yijing Huang, Kinnari Santosh Arte, Chanakya D. Patil, Qi Zhou, Li Qu

“…Various solid-state characterizations, including particle size, particle morphology, crystallinity, water sorption/desorption, and surface composition, were conducted to evaluate the properties of spray-dried colistin with/without leucine or trileucine. …”
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Morinda officinalis oligosaccharides alleviate chronic unpredictable mild stress-induced depression through the BDNF/TrkB/CREB pathway and symptoms of sexual dysfunction in mice by Mengjie He, Mengying Hu, Tingqiao Wang, Zeping Zuo, Hongkai Li, Zhiwei Zhao, Yunwen Hao, Xueling Dai, Jianfang Wang, Yaxuan Sun

“…The aim of this study was to investigate the potential effects of Morinda officinalis oligosaccharides (MOO) on depression and its concomitant symptom, sexual dysfunction.MethodsChronic unpredictable mild stress (CUMS)-induced depression model was constructed, and the effects of MOO on depression and sexual abilities were evaluated.ResultsThe results revealed that MOO was able to alleviate CUMS-induced depression-like behavior in mice, to inhibit hippocampal neuron apoptosis, to reverse monoamine neurotransmitter imbalance, increase Brain-derived neurotrophic factor (BDNF) expression levels in the hippocampus, to modulate the composition and distribution of gut microbiota, and to increase the abundance of probiotics after continuous gavage of MOO for 28 days. …”
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Application of Combined Dietary and Exercise Intervention in Pediatric Obesity and Its Impact on Anthropometric Measurements and Blood Lipid Parameters by Nie Y, Xiong F, Wang H, Yang F, Chen J

“…This comprehensive model may be an effective, non-pharmacological strategy for promoting healthy growth and managing childhood obesity.Keywords: obese children, combined diet and exercise intervention, physical measurements, blood lipid levels…”
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Valorization of wood waste for enhanced polyhydroxybutyrate production by Klebsiella sp. MK3 by Mukesh Kumar, Rohan Samir Kumar Sachan, Arun Karnwal, Dharmesh Sur, Rahul Thakur, Abhinav Kumar, Sathiyamoorthy Manickkam, Abinet Gosaye Ayanie, Hamad Almujibah

“…Media optimization using Design Expert 12.0 utilized a quadratic model, achieving a robust fit with an R² value of 98.6%. …”
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Heterogeneity of Biofilm Formation Among <i>Staphylococcus aureus</i> and Coagulase-Negative <i>Staphylococcus</i> Species in Clinically Relevant Intravenous Fat Emulsions by Gustavo R. Alvira-Arill, Oscar R. Herrera, Jeremy S. Stultz, Brian M. Peters

“…<b>Background</b>: Compared to soybean oil intravenous fat emulsion (SO-IFE), use of mixed-oil IFE (MO-IFE) is associated with reduced rates of catheter-related bloodstream infections caused by coagulase-negative <i>Staphylococcus</i> species (CoNS) in pediatric patients receiving parenteral nutrition. <b>Methods</b>: Using an in vitro biofilm model, this study aimed to assess the impact of IFEs on biofilm formation among <i>Staphylococcus</i> species. …”
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Beta-Catenin Mutations Can Impact on the Interplay Between Tumor and Immune Cells and Hepatic Microbiota in Hepatocellular Cancer by Ota Y, Driscoll J, Hill AR, Yan IK, Patel T

“…We hypothesized that β-catenin could modulate the immune microenvironment through alterations in the secretome and release of extracellular vesicles (EV) that mediate tumor and immune cell interactions and increase tumor growth within regions with attenuated immune activity and reduced microbial diversity.Methods: We used a synthetic transgenic murine model of β-catenin-driven hepatocarcinogenesis to analyze microbiome composition, diversity, and immune cell profiles in vivo. …”
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Antioxidant Activity of <i>Radix Cyathula officinalis</i> Kuan Polysaccharides and Their Modulatory Effects on the Gut Microbiota of <i>Caenorhabditis elegans</i> by Rui Li, Xinyue Chen, Lijuan Wu, Lei Xie, Mengqiu Chen, Yujie Qiu, Fan Liu, Ji Chen, Mengliang Tian

“…Their efficacy varies according to their geographic origin and processing methods. However, the systemic anti-aging mechanisms and antioxidant efficacy of RCP have not yet been comprehensively characterized. …”
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ELEMENTS OF SPORTS GYMNASTICS AS A MEANS OF IMPROVING HEALTH‐RELATED AND SKILL‐RELATED COMPONENTS OF FITNESS by Gorana Tešanović, Sasa Jovanovic, Goran Pašić, Vladimir Jakovljević, Milinko Dabović, Goran Bošnjak

“…After analysing the data obtained by statistical methods, it was found that a statistically significant change was observed after the training programme in terms of improvement in all tested components of health‐related components of fitness: cardiorespiratory fitness, strength endurance and body composition and all tested components of skill-related components of fitness: explosive strength, speed and agility. …”
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Mechanical–electric dual characteristics solid–liquid interfacing sensor for accurate liquid identification by Lingjie Xie, Bohan Lu, Zhengdi Sima, Yina Liu, Haifeng Ji, Zhenqiu Gao, Peng Jiang, Harm Van Zalinge, Ivona Z. Mitrovic, Xuhui Sun, Zhen Wen

“…With the integration of a gated recurrent unit (GRU) model, intelligent identification of ten liquids has reached an ultrahigh accuracy of 99%, opening up a pathway for portable liquid monitoring.…”
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Integration of Pseudotargeted Metabolomics and Microbiomics Reveals That Hugan Tablets Ameliorate NASH with Liver Fibrosis in Mice by Modulating Bile Acid Metabolism via the Gut Mi... by Wenran Dong, Ying Wang, Huajinzi Li, Huilin Ma, Yingxi Gong, Gan Luo, Xiaoyan Gao

“…The underlying mechanism of HGTs was investigated by the integration of microbiomics, a pseudo-sterile model, untargeted followed by pseudotargeted metabolomics, and molecular docking. …”
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Features of the implementation of the financial and legal status of municipalities, included in urban agglomerations by Svetlana M. Mironova

“…The formation of urban agglomerations is called one of the possible forms of regulation of intergovernmental relations.  The Russian model for the development of agglomerations so far follows the path of allocating inter-budget transfers from the federal budget.Agglomeration development is possible only with the interaction of all municipalities included in its composition, and the coordination of their actions, coordination of the regulatory framework of municipalities, including those aimed at optimizing budget expenditures. …”
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A triterpene-enriched natural extract from Eucalyptus tereticornis modulates the expression of genes involved in adipogenesis, lipolysis, and extracellular matrix remodeling in a p... by Sergio Acin, Alejandro Mejia-Garcia, Geysson Javier Fernandez, Norman Balcazar

“…(Myrtaceae), with ursolic acid, oleanolic acid, and ursolic acid lactone mixed with minor metabolites, provided a superior antiobesity effect than reconstituted triterpenoid mixtures in adipocyte cell lines and a pre-diabetic mouse model. Further identification of the molecular mechanisms of action of this mixture of triterpenes is required.Objective This study analyzes the effect of the natural extract and its components on early RNA expression profiles in human primary cultured adipocytes and a mouse cell line.Materials and methods RNA was sequenced using the DNBseq platform and the EnrichR software to perform gene enrichment analysis using the Gene Ontology database, Kyoto Encyclopedia of Genes and Genomes, and Reactome. …”
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Disruption of Gut Microbiota and Associated Fecal Metabolites in Collagen-Induced Arthritis Mice During the Early Stage by Wu D, Yin M, Cao D, Zhang X, Zhu Y, Wei Y, Li Y, Wen C, Zhou J

“…Further revealing the microbiota and related metabolic disorders in the preclinical stage of RA (pre-RA) is of great significance for exploration of disease mechanisms.Methods: DBA/1 mice were injected with type II collagen on days 0 and 21 to establish collagen-induced arthritis (CIA) mouse model. …”
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Randomised controlled trial of the effects of kefir on behaviour, sleep and the microbiome in children with ADHD: a study protocol by Philippa Fibert, Paul D Cotter, Alice M Gregory, Kate Lawrence, Kyriaki Myrissa, Jemima Hobbs, Miguel A Toribio-Mateas, Frits Quadt

“…Interaction between time (preintervention/postintervention) and group (probiotic/placebo) is to be analysed using a Mixed Model Analysis of Variances.Ethics and dissemination Ethical approval for the study was granted by St Mary’s University Ethics Committee. …”
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Contextual Factors, Health History, and Daily Living Activities for Ovarian Cancer Risks: A Case-Control Study in Indonesia by Restuning Widiasih, Windy Natasha, Tosin Popoola, Katherine Nelson

“…Methods: This retrospective case-control study included 408 women with a 1:1 balanced composition: 204 women diagnosed with ovarian cancer and 204 without. …”
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