iGPCR-drug: a web server for predicting interaction between GPCRs and drugs in cellular networking. by Xuan Xiao, Jian-Liang Min, Pu Wang, Kuo-Chen Chou

“…In the predictor, the drug compound is formulated by a 2D (dimensional) fingerprint via a 256D vector, GPCR by the PseAAC (pseudo amino acid composition) generated with the grey model theory, and the prediction engine is operated by the fuzzy K-nearest neighbour algorithm. …”
Get full text

Replenishment of intracellular magnesium deficiency in cardiac arrhythmias: focus on the physicochemical properties of complex compounds by Ya. G. Bozhko, N. A. Belokonova, O. M. Medvedeva, K. A. Butova, M. V. Arkhipov

“…To identify the most promising drug composition for replenishing intracellular magnesium deficiency by eveluating the physicochemical properties of magnesium complex compounds and conducting experiments on isolated rat atrial cardiomyocytes.Materials and methods. …”
Get full text

A promising approach to diabetic osteoporosis: oxymatrine’s effects on gut microbiota and osteoblasts by Yang Zhang, Yiwen Zhu, Mengying Li, Minjie Zhang, Dan Shou, Peijian Tong

“…This study aimed to investigate its effects on diabetic osteoporosis (DOP) and explore the underlying mechanisms involving gut microbiota and osteogenic regulation. Methods In a rat model of T2DM, intragastric Oxymatrine was used to study trabecular bone repair through bone microstructure and histopathology analyses. …”
Get full text

Clinically applicable antibiotic modification of ready-to-use calcium phosphate cement pastes by Alicia Zeiner, Johannes K. Konrad, Sandra Hinderer, Andreas Hoess, Sascha Heinemann, Uwe Gbureck

“…While the modification of classical aqueous powder/liquid cement pastes with antibiotics has been extensively investigated, only a few studies previously published aimed at drug modification of premixed cement pastes. Methods A simple method for modifying such ready-to-use pastes with the model antibiotic vancomycin is described. …”
Get full text

Life Cycle Assessment of Municipal Solid Waste Management Strategies in Babolsar: Evaluating Environmental Impacts and Energy Consumption by Babak Sheydaei, Gholamreza Nabi, Fatemeh Yazdian

“…This study aims to evaluate the environmental impacts of various MSWM scenarios using the Life Cycle Assessment (LCA) methodology with the IWM-2 model. Seven scenarios were examined, ranging from landfilling without energy recovery to advanced combinations incorporating composting, recycling, and energy recovery. …”
Get full text

Development and validation of the Meiji Nutritional Profiling System for children by Ryota Wakayama, Tao Yu, Adam Drewnowski, Satoshi Takasugi, Tomohito Horimoto, Chiharu Tsutsumi

“…BackgroundThe Meiji Nutritional Profiling System (Meiji NPS) takes into account life-stage differences and addresses specific health challenges in different age groups in Japan.ObjectivesThis study aimed to develop the Meiji NPS for younger (3–5 years) and older (6–11 years) children to encourage product reformulation and promote proper growth and development.MethodsMeiji NPS scores for 1,091 foods listed in the Japanese Food Standard Composition Table were calculated and compared with nutrient profiles (NPs) for children developed by the WHO Regional Office for the Western Pacific or Nutrient-Rich Foods Index 9.3 (NRF9.3).ResultsFor younger children, the Meiji NPS scores ranged from −442.3 to 423.9, and for older children, the Meiji NPS scores ranged from −265.5 to 386.5. …”
Get full text

Research progress in near-infrared spectroscopy for detecting the quality of potato crops by Wenjing Ren, Qingqing Jiang, Wenliang Qi

“…The technique facilitates the assessment of the composition and characteristics of the materials being analysed. …”
Get full text

Framework for Groove Rating in Exercise-Enhancing Music Based on a CNN–TCN Architecture with Integrated Entropy Regularization and Pooling by Jiangang Chen, Junbo Han, Pei Su, Gaoquan Zhou

“…Our method also surpasses the performance of CNN and other machine-learning models, including long short-term memory (LSTM) networks and support vector machine (SVM) variants. …”
Get full text

Clostridium Butyricum 337279 shapes the gut microbiota to attenuate metabolic disorder in diet-induced obese mice by Xuejiao Zhang, Zhiyu Li, Junjun Cao, Haipeng Sun, Wenyan Niu

“…The effect of C.B on obese mice remains unclear.MethodsA high fat diet (HFD)-induced mouse model of obesity was constructed, and the mice were treated with C.B to examine their role on obesity and related metabolic disorder. …”
Get full text

Comparative analysis of the fecal microbiota in Père David's deer and five other captive deer species by Caiquan Zhao, YuChen Yang, Peng Zhao, LiGe Bai

“…Various factors influence the composition and function of the gut microbial community. …”
Get full text

OPTIMIZATION OF INCOME OF THE PERSONNEL OF THE ENTERPRISES OF THE FOOD INDUSTRY by G.M. Tarasiuk, T.P. Ostapchuk, T.V. Musiiets, Ya.M. Laguta, S.Yu. Biriuchenko

“…The article proves that the successful operation of the enterprise is impossible without the coordination of the interests of the employer and its staff in the field of income generation, so this process needs to be optimized using mathematical modeling methods. Since the income of personnel, first of all, belongs to the sphere of personnel management of the enterprise, the indicators of the goal are indicators of the effectiveness of the use of labor resources. …”
Get full text

LoRA Fusion: Enhancing Image Generation by Dooho Choi, Jeonghyeon Im, Yunsick Sung

“…This method ensures stability when merging multiple LoRA modules and performs comparably to fully retrained LoRA models. …”
Get full text

Parameters of a robotic loading device for selection seeder by A. S. Chulkov, L. S. Shibryaeva

“…(Research purpose) The research aims to calculate the geometric parameters and identify the cassette material in the development of a robotic cassette loading device for the selection seeder. (Materials and methods) The geometric parameters of the cassettes are determined based on the existing cassette loading device of the model SSS-2-6 selection seeder and the selection sowing specifi cations. …”
Get full text

Examining the Correlations Between Industry 4.0 Assets, External and Internal Risk Factors and Business Performance Among Hungarian Food Companies by Erdei, E., Kossa, G., Kovács, S., Popp, J., Oláh, J

“…The data were then analysed using a number of statistical methods: Cronbach's alpha index, factor analysis, PLS pathway analysis, indicator reliability index, composition reliability index, mean explained variance index, Fornell-Larcker criterion, heterotrait-monotrait ratio, magnitude of effect, fit goodness, predictive relevance, and road model coefficients. …”
Get full text

Overview on the subsurface structure-tectonic controls in the northwest Bahariya, Western Desert, Egypt by Ahmad A. Azab, Mohamed H. Saad, Marwa Z. Elsawy

“…The basement is generally of acidic composition with some basic intrusions penetrate the boundary faults.…”
Get full text

Music-stylized hierarchical dance synthesis with user control by Yanbo Cheng, Yichen Jiang, Yingying Wang

“…We use a high-level choreography module built as a Transformer-based sequence model to predict the long-term structure of a dance genre and a low-level realization module that implements dance stylization and synchronization to match the musical input or user preferences. …”
Get full text

Independent association of weight-adjusted waist index with asthma in U.S. adolescents: Mediating roles of eosinophil percentage, total cholesterol, and HDL cholesterol. by Lei He, Yingxia Deng, Xiaohua Liu, Yao Wang, Jing Tang

“…<h4>Methods</h4>WWI was calculated based on waist circumference (cm) divided by the square root of weight (kg). …”
Get full text

Determinants of COVID-19 Case Fatality Rate in the United States: Spatial Analysis Over One Year of the Pandemic by Niranjan J. Kathe, Rajvi J. Wani

“…**Conclusion:** The spatial models identified percent positive for COVID-19, stringency index, elderly, college education, race/ethnicity, residential segregation, premature mortality, income inequality, workforce composition, and rurality as important ecological determinants of the geographic disparities in COVID-19 CFR.…”
Get full text

Predicting the frost heaving of bottom ash value for road design by A. A. Lunev, D. A. Razuvaev, V. V. Golubenko, M. G. Chakhlov

“…This makes it possible to determine the degree of frost heaving of ash and slag systems based on the grain size composition and the calculated characteristics of the subgrade.…”
Get full text

Integrated hydrogeochemical and spatial assessment of groundwater quality using multivariate statistics and GIS: a case study from northeastern Iran by Maryam Tajbakhshian

“…The integrated approach provides a replicable model for groundwater quality monitoring and decision-support in data-scarce arid environments. …”
Get full text