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3281
Identification of a PANoptosis-related gene signature reveals therapeutic potential of SFRP2 in pulmonary arterial hypertension
Published 2025-04-01“…The immune landscape in PAH was characterized using the CIBERSORT algorithm, providing insights into immune cell composition and its role in disease progression. Gene expression was further validated using a rat PAH model and pulmonary artery fibroblasts (PAAFs), while hub gene functions were investigated at the cellular level through Western blot, CCK-8, and flow cytometry assays.ResultsThrough integrated transcriptomic analysis, SFRP2 was identified as a feature gene related to PAH and PANoptosis. …”
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3282
Single‐Cell Transcriptomics Reveals a Pivotal Role of DOCK2 in Sjögren Disease
Published 2024-12-01“…We further determined the therapeutic effect of inhibiting dedicator of cytokinesis 2 (DOCK2) shared by novel clusters of CD8+ T cells in an SjD mouse model. Methods This study employed single‐cell RNA sequencing to examine the composition and dynamics of immune cells in the salivary glands of SjD mice. …”
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3283
Artificial Soil Environment Justification for Laboratory Studies of Wear and Traction Characteristics of Soil-Cutting Working Bodies
Published 2020-09-01“…(Materials and methods) An artificial soil environment was developed by introducing filamentous components 5-25 millimeters long into its composition.…”
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3284
THE IMPACT OF GENDER DIVERSITY ON EARNINGS QUALITY OF LISTED FINANCIAL SERVICES FIRMS IN NIGERIA: ANALYSIS OF TWO-STAGE LEAST SQUARES
Published 2025-01-01“…Earnings quality was measured using the accruals quality model, evaluating the reliability of reported earnings. …”
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3285
Restoring Technology and a Seeding Unit for Recovering Mountain Meadow and Pasture Ecosystems
Published 2023-06-01“…It is established that the laboratory model of the unit complies with the agrotechnical requirements and terms of reference. …”
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3286
Tips and tricks for gut microbiota investigation using scanning electron microscopy (SEM): going from sample preparation to imaging and landscape analysis
Published 2025-12-01“…This study introduces a novel rapid technique using tabletop scanning electron microscopy (SEM) for investigating GM composition, focusing on Clostridioides difficile infection (CDI) as a representative model for dysbiosis-related diseases. …”
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3287
Dynamics of recurrent neural networks with piecewise linear activation function in the context-dependent decision-making task
Published 2025-03-01“…Additionally, it seeks to develop a methodology for analyzing such models based on dynamical systems theory. Methods. …”
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3288
Magnetohydrodynamic Blood-Carbon Nanotube Flow and Heat Transfer Control via Carbon Nanotube Geometry and Nanofluid Properties for Hyperthermia Treatment
Published 2025-03-01“…The central idea is that by adjusting the concentration, shape, and size of CNTs, as well as the strength of an external magnetic field, heat transfer can be controlled for targeted treatment. A theoretical model is developed to analyze laminar natural convection within a simplified rectangular porous enclosure resembling a tumor, considering the composition of blood, and the geometric characteristics of CNTs, including the interfacial nanolayer thickness. …”
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3289
Simulación del vaciado continuo de perfiles de aceros al carbono de baja aleación//Simulation of the continuous casting of low carbon steel profiles
Published 2012-12-01“…</p><p>_______________________________________________________________________________</p><p><strong>Abstract</strong><br /><br />In this paper an algorithm to simulate the process of continuous casting based on a physical – mathematical model using finite element methods was presented. …”
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3290
Predicting mechanical properties of low-alloy steels using features extracted from Electron Backscatter Diffraction characterization
Published 2024-11-01“…However, the complexities of microstructure pose challenges for straightforward modeling, thereby complicating research efforts. This study introduces a series of multi-parametric quantification methods based on Electron Backscatter Diffraction (EBSD) data tailored to the microstructural characteristics of low-alloy steels. …”
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3291
Skin microbiome differences in pancreatic adenocarcinoma, other cancers, and healthy controls: a pilot study
Published 2025-02-01“…While recent studies have explored the microbiome’s role in various types of cancer compared to healthy patients, this pilot study is the first to investigate differences in the skin microbiome composition among pancreatic adenocarcinoma patients, individuals with other cancers, and cancer-free controls.MethodsThe study characterizes the skin microbiome’s potential associations with cancer status by analyzing skin swabs from the forehead and cheek of 58 participants using Next Generation Sequencing (NGS), differential abundance analysis, and machine learning techniques.ResultsThe study results indicated that the cancer group displayed a significantly higher mean alpha diversity compared to the control group. …”
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3292
Development and testing of platform-based aviation gravity instrument
Published 2024-11-01“…Taking a certain type of domestically produced aviation gravity meter as an example, this paper introduces the working principle, equipment composition, and field performance testing methods of the three-axis inertial stabilizer platform aviation gravimeter. …”
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3293
Thermogravimetric Assessment and Kinetic Analysis of Forestry Residues Combustion
Published 2025-06-01“…For this, the complexity of kinetic study is addressed in this paper by using different approaches: isoconversional and model-fitting methods. However, the use of isoconversional methods proved ineffective for determining reliable kinetic parameters, due to their sensitivity to particle conversion. …”
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3294
Determination of Biochemical and Metabolomic Characteristics of Sheep Blood Serum and Their Application in Clinical Practice
Published 2025-07-01“…Reliable and reproducible preclinical testing is essential before any diagnostic method can be introduced into clinical use. A thorough understanding of the safety and efficacy of such methods in animal models is a prerequisite for initiating human trials. …”
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3295
A.C. ELECTRIC DRIVE WITH PULSE-WIDTH MODULATION CONTROL
Published 2014-02-01“…The method makes it possible to improve harmonic composition of the voltage. …”
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3296
Optimal Network Design for Municipal Waste Management: Application to the Metropolitan City of Rome
Published 2024-08-01“…The mathematical model was also used for evaluating strategic scenarios in a “what-if” analysis, allowing the municipal collection company to assess location options for depots, waste treatment facilities, and transshipment points, as well as to optimize the fleet composition and driver allocation during work shifts. …”
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3297
Visible and Near-Infrared Reflectance Spectroscopy for Investigating Soil Mineralogy: A Review
Published 2018-01-01“…We further critically review applications of chemometric methods and related model building in spectroscopic soil mineral studies. …”
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3298
Action Mechanism and Simulation Research on Collaborative Knowledge Management Capability to Innovate Smart Services of New Think Tanks
Published 2024-06-01“…Through system dynamics simulation, it is possible to observe which key factors should be emphasized in long-term development, providing reference basis for organizational development. [Method/Process] This article takes knowledge ecology as the theoretical support, analyzes the composition of collaborative knowledge management capability and its mechanism of action on innovative smart services in new think tanks, and uses system dynamics methods to construct a model of the effect of collaborative knowledge management capability on innovative smart services in new think tanks. …”
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3299
A systematic approach to the quality assessment of printed products
Published 2024-08-01“…To create one or another model of the system, it is first necessary to carry out its verbal and informational description and tuple recording. …”
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3300
Determination of Folic Acid in Multivitamin Preparations by Reversed Phase HPLC
Published 2021-10-01“…Materials and methods: The Agilent 1260 Infinity II LC system with a diode array detector (280 nm), isocratic elution mode, C8- and C18-bonded silica gel chromatographic columns, model mixtures containing folic acid, cyanocobalamin, ferrous sulfate, and potassium iodide, were used in the study.Results: The lowest relative standard deviation of the folic acid peak area (RSD=0.09%), and the lowest asymmetry factor (As=1.04) for folic acid were observed for the model mixture “ferrous sulfate+folic acid+cyanocobalamin” and the following test conditions. …”
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