Screen Time Is Associated With Cardiometabolic and Cardiovascular Disease Risk in Childhood and Adolescence by David Horner, Marie Jahn, Klaus Bønnelykke, Bo Chawes, Trine Flensborg‐Madsen, Ann‐Marie Malby Schoos, Jakob Stokholm, Morten Arendt Rasmussen

“…A predicted cardiovascular risk score, derived from Cox models trained on UK Biobank data, was also assessed as an outcome. …”
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Long-term exposure to multiple air pollutants and multi-level socioeconomic status: joint effects on age-related macular degeneration, subsequent ocular comorbidity, and death in m... by Yang Yang, Liangkai Chen, Qichen Liu, Min Mu, Jing Huang, Guangming Zhang, Qianqian Song

“…However, no study has explored the combined effects of air pollutants and SES on (1) age-related macular degeneration (AMD) incidence; (2) trajectories from baseline to AMD, subsequent ocular comorbidity (OCMD), and mortality; and (3) life expectancy in middle-aged and older adults. Methods Using UK Biobank data, we created two composite air pollution scores (APS) and assessed SES at individual and neighborhood levels. …”
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Baseline type 2 biomarker levels and clinical remission predictors in children with asthma by Mengmeng Chen, Mengmeng Chen, Congcong Li, Qiuyan Yang, Huijie Zhang, Yanli Zhang, Na Wang, Na Wang, Jingcheng Dong, Jingcheng Dong

“…Integration with lung function and IgE may form a composite biomarker panel for remission evaluation. …”
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Protocol for an observational study to assess the impact of pharmacogenetics on outcomes in vascular surgery (PROSPER) by John H McDermott, William G Newman, Stuart Wright, Kerry Anne Burke, Selman Mirza, Nicholas S Greaves

“…Secondary outcomes are risk of MALE at 1 year, risk of major adverse cardiovascular events (MACE) or death from any cause at 1 year, death within 30 days of revascularisation, minor re-interventions at 1 year, total number of re-interventions at 1 year and rate of systemic or gastrointestinal bleed at 1 year.Risk of amputation, MALE and MACE will be analysed using Cox models. All remaining outcomes will be analysed using negative binomial models. …”
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IL-17A Levels and Progression of Kidney Disease Following Hospitalization with and without Acute Kidney Injury by Jason A. Collett, Alexander H. Flannery, Lucas J. Liu, Tomonori Takeuchi, David P. Basile, Javier A. Neyra

“…In adjusted multivariable models, IL-17A levels were not independently associated with progression of kidney disease. …”
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Association of urbanization-related factors with tuberculosis incidence among 1992 counties in China from 2005 to 2019: a nationwide observational study by Yaping Wang, Xiaoqiu Liu, Yuhong Li, Min Liu, Yiheng Wang, Hongliang Zhang, Jue Liu, Yanlin Zhao

“…We aimed to assess the association between urbanization factors and TB incidence in China. Methods We evaluated urbanization at the county level in China from 2005 to 2019 using a composite index integrating population density, gross domestic product (GDP, per capita), hospital beds per 1000 population, nighttime light (NTL), and normalized difference vegetation index (NDVI). …”
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Interplay between worsening kidney function and cardiovascular events in patients with type 2 diabetes: an analysis from the ACCORD trial by João Pedro Ferreira, Patrick Rossignol, Faiez Zannad, Abhinav Sharma, Diana Ferrao, Francisco Vasques-Novoa, Adelino Leite-Moreira

“…We have used a large population of patients with T2D and a high cardiovascular risk enrolled in the Action to Control Cardiovascular Risk in Diabetes Study.Research design and methods Time-updated, joint, and multistate modeling were used. …”
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AI-powered EFL pedagogy: Integrating generative AI into university teaching preparation through UTAUT and activity theory by Muhammad Zaim, Safnil Arsyad, Budi Waluyo, Havid Ardi, Muhd. Al Hafizh, Muflihatuz Zakiyah, Widya Syafitri, Ahmad Nusi, Mei Hardiah

“…The study is particularly relevant as generative AI offers significant potential to improve teaching efficiency and content personalization, yet its adoption presents challenges in aligning outputs with educational standards and maintaining meaningful teacher-student interaction. Using a mixed-methods approach, the research combined quantitative data from structured questionnaires with qualitative insights from reflective compositions, where lecturers critically evaluated their experiences with generative AI. …”
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Legume-based rotation alters soil eukaryotic community and improves soil multifunctionality by Tingwei Meng, Yi Fan, Yiheng Tao, Yi Wu, Shuang Pang, Wei Yang, Xiaoyu Guo, Ximei Zhang

“…Structural equation modeling (SEM) analysis revealed that the maize-soybean rotation improved soil multifunctionality by increasing fungal richness and complicating protistan community structure. …”
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Park quality and chronic disease: A city-level analysis by Lauren S. Pongetti, OTR/L, Fazlay S. Faruque, PhD, Benjamin H. Walker, PhD

“…Methods: Using mixed-effects regression models with repeated measures nested within cities, we examined associations between ParkScore and age-adjusted prevalence of high blood pressure, cancer, coronary heart disease, chronic obstructive pulmonary disease, diabetes, chronic kidney disease, obesity, and stroke. …”
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Valuing health-related quality of life among the Indian population: a protocol for the Development of an EQ-5D Value set for India using an Extended design (DEVINE) Study by Atul Sharma, Manmeet Kaur, Shankar Prinja, Gaurav Jyani, Sitanshu Sekhar Kar, Mayur Trivedi, Binod Patro, Fredrick Purba, Star Pala, Swati Raman, Shalu Jain

“…The aim of this paper is to describe the methods for the Development of an EQ-5D Value set for India using an Extended design (DEVINE) Study. …”
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Oxidative balance score and mortality: mediating role of insulin resistance across age strata in the NHANES cohort by Lin Zhang, Lin Zhang, Heming Zhang, Heming Zhang, Hongxia Xiang, Jiachen Zhang, Wei Gong, Junjie Xv, Xue Yu

“…BackgroundThis study examined the association between oxidative balance score (OBS), a composite measure of oxidative/antioxidative factors, and mortality, while investigating insulin resistance (IR) indices as potential mediators using a nationally representative cohort.MethodsA cohort of 11,849 U. …”
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Computerized cognitive testing to capture cognitive decline in Alzheimer's disease: Longitudinal findings from the ARMADA study by Roos J. Jutten, Emily H. Ho, Tatiana Karpouzian‐Rogers, Carol van Hulle, Cynthia Carlsson, Hiroko H. Dodge, Cindy J. Nowinski, Richard Gershon, Sandra Weintraub, Dorene M. Rentz

“…Linear mixed‐effect models correcting for demographics were used to examine cross‐sectional and longitudinal NIHTB‐CB scores in individuals across the clinical AD spectrum. …”
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Healthy lifestyle factors and combined macrovascular and microvascular events in diabetes patients with high cardiovascular risk: results from ADVANCE by Shoujiang You, Danni Zheng, Yanan Wang, Qiang Li, Tu N. Nguyen, Ruth Peters, Xiaoying Chen, Xia Wang, Yongjun Cao, Diederick E. Grobbee, Stephen Harrap, Giuseppe Mancia, Bryan Williams, Neil R. Poulter, Liu Lisheng, Michel Marre, Pavel Hamet, Craig S. Anderson, Mark Woodward, John Chalmers, Katie Harris

“…Multivariable Cox models were used to determine associations of 0, 1, 2, and ≥ 3 HLFs with vascular events and all-cause mortality. …”
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Acceptability of a 250 mg levofloxacin formulation in children receiving TB preventive treatment by S.E. Purchase, J. Brigden, J.A. Seddon, N.A. Martinson, L. Fairlie, S. Staples, A. Poswa, T. Duong, H.S. Schaaf, A.C. Hesseling

“…Likert scales were used to grade 6 domains of acceptability, and a composite acceptability (CA) outcome was generated. …”
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Protocol for a multisite randomised controlled trial assessing the effect of the Telehealth for Early Developmental Intervention in babies born very preterm (TEDI-Prem) programme o... by Alicia J Spittle, Peter J Anderson, Angela T Morgan, Rachel Schembri, Li Huang, Kim Dalziel, Rod W Hunt, Katherine Lee, Anne E Holland, Karli Treyvaud, Abbey L Eeles, Stacey Dusing, Shaaron Brown, Susan M Fehring, Gillian Henty, Elizabeth Kozaris

“…Here we present the protocol outlining a multicentre, pragmatic, parallel-group, randomised controlled trial to determine the efficacy of TEDI-Prem plus usual care, compared with usual care alone.Methods and analysis We will recruit 466 VPT infants from the neonatal units of five hospitals in Victoria, Australia. …”
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Passive immunotherapy for adults hospitalized with COVID-19: An individual participant data meta-analysis of six randomized controlled trials. by Kirk U Knowlton, Lianne K Siegel, Christina E Barkauskas, Sanjay Bhagani, Nila J Dharan, Edward M Gardner, Robert L Gottlieb, Marie Helleberg, Helene C Highbarger, Thomas L Holland, Christian Kjer Heerfordt, Susana Lazarte, Lindsey M Leither, Joseph Lutaakome, Magdalena Ardelt, Eleftherios Mylonakis, Sean W X Ong, Jeffrey Scott Overcash, Hassan Taha, Phyllis C Tien, Barbara W Trautner, David Vallee, Amy C Weintrob, Giota Touloumi, Abdel G Babiker, STRIVE ACTIV-3/TICO Study Group

“…Within each trial, three major outcomes (sustained recovery, mortality, and a composite safety outcome) were compared between treatment and placebo using Fine-Gray and Cox proportional hazards models. …”
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Transdiagnostic mechanisms of mental health during the COVID-19 pandemic: associations of childhood trauma, maladaptive personality traits, emotion regulation, mentalizing, and pan... by Julia Holl, Julia Holl, Anna Berning, Laura Kling, Svenja Taubner, Anna K. Georg, Jana Volkert

“…The aim of this study is to examine the associations with these transdiagnostic factors in relation to PR distress and psychopathological symptoms.Materials and methodsUsing a cross-sectional study design, we investigated a convenience sample of 6,451 adults (mean age = 44.1; SD = 11.8; 69.1% female, 30.3% male, 0.01% diverse) recruited via social media platforms in German-speaking countries (August 2020 – February 2021) by utilizing self-report instruments (PID5BF+, MentS, DERS-SF, PHQ-9, GAD-7, a composite PR distress score). …”
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Assessment of Digitalization of Interaction Between the State and Citizens by E. I. Dobrolyubova, A. N. Starostina

“…To achieve the objective, theoretical methods (comparative analysis, synthesis, and generalization), modelling, and correlation analysis were used. …”
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Brain Amyloid Deposition and Longitudinal Cognitive Decline in Nondemented Older Subjects: Results from a Multi-Ethnic Population. by Yian Gu, Qolamreza R Razlighi, Laura B Zahodne, Sarah C Janicki, Masanori Ichise, Jennifer J Manly, D P Devanand, Adam M Brickman, Nicole Schupf, Richard Mayeux, Yaakov Stern

“…<h4>Objective</h4>We aimed to whether the abnormally high amyloid-β (Aβ) level in the brain among apparently healthy elders is related with subtle cognitive deficits and/or accelerated cognitive decline.<h4>Methods</h4>A total of 116 dementia-free participants (mean age 84.5 years) of the Washington Heights Inwood Columbia Aging Project completed 18F-Florbetaben PET imaging. …”
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